KR20190130608A - 면역종양학을 위한 조성물 및 방법 - Google Patents
면역종양학을 위한 조성물 및 방법 Download PDFInfo
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- KR20190130608A KR20190130608A KR1020197030551A KR20197030551A KR20190130608A KR 20190130608 A KR20190130608 A KR 20190130608A KR 1020197030551 A KR1020197030551 A KR 1020197030551A KR 20197030551 A KR20197030551 A KR 20197030551A KR 20190130608 A KR20190130608 A KR 20190130608A
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Mycology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762475024P | 2017-03-22 | 2017-03-22 | |
| US62/475,024 | 2017-03-22 | ||
| PCT/US2018/023631 WO2018175636A2 (en) | 2017-03-22 | 2018-03-21 | Compositions and methods for immunooncology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20190130608A true KR20190130608A (ko) | 2019-11-22 |
Family
ID=61972210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197030551A Withdrawn KR20190130608A (ko) | 2017-03-22 | 2018-03-21 | 면역종양학을 위한 조성물 및 방법 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11851659B2 (enExample) |
| EP (1) | EP3601561A2 (enExample) |
| JP (2) | JP2020513832A (enExample) |
| KR (1) | KR20190130608A (enExample) |
| CN (1) | CN110832075A (enExample) |
| AU (1) | AU2018237159A1 (enExample) |
| BR (1) | BR112019018124A2 (enExample) |
| CA (1) | CA3054621A1 (enExample) |
| EA (1) | EA201992232A1 (enExample) |
| IL (1) | IL268684A (enExample) |
| MX (1) | MX2019011272A (enExample) |
| PH (1) | PH12019502171A1 (enExample) |
| RU (1) | RU2019133280A (enExample) |
| SG (1) | SG11201907434RA (enExample) |
| WO (1) | WO2018175636A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3280729T3 (pl) | 2015-04-08 | 2022-08-22 | Novartis Ag | Terapie cd20, terapie cd22 i terapie skojarzone komórką eksprymującą chimeryczny receptor antygenowy (car) cd19 |
| WO2017093969A1 (en) | 2015-12-04 | 2017-06-08 | Novartis Ag | Compositions and methods for immunooncology |
| AU2017248259A1 (en) * | 2016-04-07 | 2018-10-25 | Bluebird Bio, Inc. | Chimeric antigen receptor T cell compositions |
| JP7467117B2 (ja) | 2016-10-07 | 2024-04-15 | ノバルティス アーゲー | 癌の治療のためのキメラ抗原受容体 |
| MA50849A (fr) * | 2017-10-26 | 2020-09-02 | Vertex Pharma | Substances et procédés pour le traitement d'hémoglobinopathies |
| US20210347851A1 (en) * | 2018-09-28 | 2021-11-11 | Novartis Ag | Cd19 chimeric antigen receptor (car) and cd22 car combination therapies |
| KR102946444B1 (ko) | 2018-11-16 | 2026-04-02 | 라파 쎄라퓨틱스 엘엘씨 | 제조된 t 세포로 암을 치료하는 방법 |
| EP3938510A1 (en) * | 2019-03-11 | 2022-01-19 | Sorrento Therapeutics, Inc. | Improved process for integration of dna constructs using rna-guided endonucleases |
| MX2021013218A (es) * | 2019-05-01 | 2021-12-10 | Pact Pharma Inc | Composiciones y metodos para el tratamiento del cancer usando una terapia con celulas t modificadas con tet2. |
| US12357704B2 (en) | 2019-05-06 | 2025-07-15 | Thomas Malcolm | Tailored hypoimmune nanovesicular delivery systems for cancer tumors |
| WO2021119006A1 (en) * | 2019-12-09 | 2021-06-17 | Caribou Biosciences, Inc. | Crispr abasic restricted nucleotides and crispr accuracy via analogs |
| EP4110356A4 (en) * | 2020-02-28 | 2024-03-27 | Wisconsin Alumni Research Foundation | NON-VIRAL GENERATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS OBTAINED BY GENE EDITING |
| WO2021231806A1 (en) | 2020-05-13 | 2021-11-18 | Rapa Therapeutics, Llc | Antigen presenting t cells, sensitized, manufactured t cells and methods of treatment using the same |
| CN115885038A (zh) * | 2020-06-17 | 2023-03-31 | 国立大学法人京都大学 | 表达嵌合抗原受体的免疫活性细胞 |
| IL300994A (en) * | 2020-08-28 | 2023-04-01 | Arsenal Biosciences Inc | Transgenic immune cells with priming receptors |
| CN114164231B (zh) * | 2020-09-10 | 2024-05-17 | 上海邦耀生物科技有限公司 | 对细胞中的靶位点进行基因编辑的方法 |
| CN114525259B (zh) * | 2020-11-03 | 2025-02-14 | 南京北恒生物科技有限公司 | 靶向cd7的嵌合抗原受体及其用途 |
| WO2022137181A1 (en) * | 2020-12-23 | 2022-06-30 | Crispr Therapeutics Ag | Co-use of lenalidomide with car-t cells |
| WO2023274386A1 (zh) * | 2021-07-01 | 2023-01-05 | 宁波茂行生物医药科技有限公司 | 靶向egfr的通用型car-t细胞及其制备方法 |
| CN113846070B (zh) * | 2021-10-18 | 2023-05-16 | 翌圣生物科技(上海)股份有限公司 | 高活性的mTET2酶突变体、其编码DNA及其应用 |
| KR102521500B1 (ko) * | 2021-12-02 | 2023-04-14 | 한국화학연구원 | 증진된 효능을 갖는 면역세포 |
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| WO2018175636A2 (en) | 2018-09-27 |
| BR112019018124A2 (pt) | 2020-04-07 |
| WO2018175636A3 (en) | 2018-11-22 |
| SG11201907434RA (en) | 2019-10-30 |
| IL268684A (en) | 2019-10-31 |
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