KR20170093988A - Gst-pi 유전자 조정을 위한 rna 제제 - Google Patents

Gst-pi 유전자 조정을 위한 rna 제제 Download PDF

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KR20170093988A
KR20170093988A KR1020177020901A KR20177020901A KR20170093988A KR 20170093988 A KR20170093988 A KR 20170093988A KR 1020177020901 A KR1020177020901 A KR 1020177020901A KR 20177020901 A KR20177020901 A KR 20177020901A KR 20170093988 A KR20170093988 A KR 20170093988A
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synthetic
description
artificial sequence
dna
rna molecule
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웬빈 잉
겐지로우 미노미
옌스 하르보르트
히로카즈 다카하시
에리카 데라다
준 장
모하마드 아흐마디안
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닛토덴코 가부시키가이샤
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KR1020177020901A 2014-12-26 2015-12-28 Gst-pi 유전자 조정을 위한 rna 제제 Withdrawn KR20170093988A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JPJP-P-2014-266198 2014-12-26
JP2014266198 2014-12-26
US201562184239P 2015-06-24 2015-06-24
US62/184,239 2015-06-24
US201562266664P 2015-12-13 2015-12-13
US62/266,664 2015-12-13
PCT/US2015/067561 WO2016106406A2 (en) 2014-12-26 2015-12-28 Rna agents for gst-pi gene modulation

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KR20170093988A true KR20170093988A (ko) 2017-08-16

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Family Applications (4)

Application Number Title Priority Date Filing Date
KR1020177020901A Withdrawn KR20170093988A (ko) 2014-12-26 2015-12-28 Gst-pi 유전자 조정을 위한 rna 제제
KR1020177020894A Withdrawn KR20170098929A (ko) 2014-12-26 2015-12-28 Hsp47 를 표적으로 하는 rnai 분자를 이용하는 악성 종양에 대한 치료적 조성물 및 방법
KR1020177020900A Withdrawn KR20170096199A (ko) 2014-12-26 2015-12-28 Kras 돌연변이와 관련된 악성 종양을 치료하기 위한 방법 및 조성물
KR1020177020898A Active KR102527430B1 (ko) 2014-12-26 2015-12-28 Gst-pi 유전자 조정을 위한 rna 간섭 제제

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KR1020177020894A Withdrawn KR20170098929A (ko) 2014-12-26 2015-12-28 Hsp47 를 표적으로 하는 rnai 분자를 이용하는 악성 종양에 대한 치료적 조성물 및 방법
KR1020177020900A Withdrawn KR20170096199A (ko) 2014-12-26 2015-12-28 Kras 돌연변이와 관련된 악성 종양을 치료하기 위한 방법 및 조성물
KR1020177020898A Active KR102527430B1 (ko) 2014-12-26 2015-12-28 Gst-pi 유전자 조정을 위한 rna 간섭 제제

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US (14) US10264976B2 (enExample)
EP (9) EP3236969A4 (enExample)
JP (10) JP6793649B2 (enExample)
KR (4) KR20170093988A (enExample)
CN (7) CN107108686B (enExample)
AU (4) AU2015369598A1 (enExample)
BR (2) BR112017013597B1 (enExample)
CA (4) CA2972265A1 (enExample)
RU (4) RU2756253C2 (enExample)
WO (7) WO2016106402A1 (enExample)

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US10264976B2 (en) 2014-12-26 2019-04-23 The University Of Akron Biocompatible flavonoid compounds for organelle and cell imaging
US20180002702A1 (en) 2014-12-26 2018-01-04 Nitto Denko Corporation Methods and compositions for treating malignant tumors associated with kras mutation
US10792299B2 (en) 2014-12-26 2020-10-06 Nitto Denko Corporation Methods and compositions for treating malignant tumors associated with kras mutation
ES2789049T3 (es) * 2014-12-26 2020-10-23 Nitto Denko Corp Agentes de interferencia de ARN para modulación génica de GST-pi
US11045488B2 (en) 2014-12-26 2021-06-29 Nitto Denko Corporation RNA interference agents for GST-π gene modulation
CN107708739A (zh) 2015-06-24 2018-02-16 日东电工株式会社 可电离化合物、组合物及它们的用途
KR102740699B1 (ko) 2015-12-13 2024-12-09 닛토덴코 가부시키가이샤 높은 활성 및 감소한 오프 타겟을 위한 sirna 구조
JP7177439B2 (ja) 2016-05-10 2022-11-24 国立大学法人 東京医科歯科大学 炎症促進因子発現抑制剤、その有効成分のスクリーニング方法、該方法に有用な発現カセット、診断薬、及び診断方法
JP2019508379A (ja) * 2017-02-16 2019-03-28 日東電工株式会社 悪性腫瘍に対する治療方法及び治療用組成物
CN111386105B (zh) * 2017-11-06 2023-09-15 日东电工株式会社 用于递送生物活性分子的膜融合化合物
CA3082006A1 (en) * 2017-11-09 2019-05-16 National University Corporation Tokyo Medical And Dental University Inhibitor of the expression of cancer-promoting factors, screening method for active ingredient thereof, expression cassette useful in said method, diagnostic drug, and diagnosticmethod
CN109777798A (zh) * 2017-11-13 2019-05-21 深圳华大生命科学研究院 一种基于CRISPR技术治疗KRAS突变恶性肿瘤的sgRNA及其应用
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