KR20170064550A - 인간화 항-ox40 항체 및 이의 용도 - Google Patents

인간화 항-ox40 항체 및 이의 용도 Download PDF

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KR20170064550A
KR20170064550A KR1020177012413A KR20177012413A KR20170064550A KR 20170064550 A KR20170064550 A KR 20170064550A KR 1020177012413 A KR1020177012413 A KR 1020177012413A KR 20177012413 A KR20177012413 A KR 20177012413A KR 20170064550 A KR20170064550 A KR 20170064550A
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cells
antibody
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스캇 에이 해먼드
마이클 오베스트
퀀 두
멜리싸 담슈로더
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메디뮨 엘엘씨
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
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    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020177012413A 2014-10-10 2015-10-07 인간화 항-ox40 항체 및 이의 용도 Withdrawn KR20170064550A (ko)

Applications Claiming Priority (3)

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US201462062431P 2014-10-10 2014-10-10
US62/062,431 2014-10-10
PCT/US2015/054490 WO2016057667A1 (en) 2014-10-10 2015-10-07 Humanized anti-ox40 antibodies and uses thereof

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US (3) US9738723B2 (enExample)
EP (1) EP3204422B1 (enExample)
JP (2) JP6794348B2 (enExample)
KR (1) KR20170064550A (enExample)
CN (1) CN107074953A (enExample)
AR (1) AR102239A1 (enExample)
AU (1) AU2015328090A1 (enExample)
BR (1) BR112017007170A2 (enExample)
CA (1) CA2963798A1 (enExample)
CL (1) CL2017000885A1 (enExample)
CO (1) CO2017004516A2 (enExample)
ES (1) ES2914177T3 (enExample)
GB (1) GB2536324A (enExample)
IL (1) IL251537A0 (enExample)
MX (1) MX2017004715A (enExample)
RU (1) RU2709742C2 (enExample)
SG (1) SG11201702826XA (enExample)
TW (1) TW201619200A (enExample)
WO (1) WO2016057667A1 (enExample)

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