RU2709742C2 - Гуманизированные антитела к ox40 и способы их применения - Google Patents

Гуманизированные антитела к ox40 и способы их применения Download PDF

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RU2709742C2
RU2709742C2 RU2017115662A RU2017115662A RU2709742C2 RU 2709742 C2 RU2709742 C2 RU 2709742C2 RU 2017115662 A RU2017115662 A RU 2017115662A RU 2017115662 A RU2017115662 A RU 2017115662A RU 2709742 C2 RU2709742 C2 RU 2709742C2
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antibody
seq
cells
fragment
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Скотт А. ХАММОНД
Майкл ОБЕРСТ
Цюнь ДУ
Мелисса ДАМШРОДЕР
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МЕДИММЬЮН, ЭлЭлСи
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
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    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/734Complement-dependent cytotoxicity [CDC]
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Plant Pathology (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2017115662A 2014-10-10 2015-10-07 Гуманизированные антитела к ox40 и способы их применения RU2709742C2 (ru)

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US201462062431P 2014-10-10 2014-10-10
US62/062,431 2014-10-10
PCT/US2015/054490 WO2016057667A1 (en) 2014-10-10 2015-10-07 Humanized anti-ox40 antibodies and uses thereof

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RU2017115662A RU2017115662A (ru) 2018-11-13
RU2017115662A3 RU2017115662A3 (enExample) 2019-05-20
RU2709742C2 true RU2709742C2 (ru) 2019-12-19

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EP (1) EP3204422B1 (enExample)
JP (2) JP6794348B2 (enExample)
KR (1) KR20170064550A (enExample)
CN (1) CN107074953A (enExample)
AR (1) AR102239A1 (enExample)
AU (1) AU2015328090A1 (enExample)
BR (1) BR112017007170A2 (enExample)
CA (1) CA2963798A1 (enExample)
CL (1) CL2017000885A1 (enExample)
CO (1) CO2017004516A2 (enExample)
ES (1) ES2914177T3 (enExample)
GB (1) GB2536324A (enExample)
IL (1) IL251537A0 (enExample)
MX (1) MX2017004715A (enExample)
RU (1) RU2709742C2 (enExample)
SG (1) SG11201702826XA (enExample)
TW (1) TW201619200A (enExample)
WO (1) WO2016057667A1 (enExample)

Cited By (1)

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RU2826983C2 (ru) * 2020-09-10 2024-09-19 Обласов Михаил Викторович Способ лечения covid-19 с помощью применения агонистов рецептора ox40 (cd134)

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