KR20160117614A - Btk 억제제의 염 및 고체 형태 - Google Patents

Btk 억제제의 염 및 고체 형태 Download PDF

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Publication number
KR20160117614A
KR20160117614A KR1020167025774A KR20167025774A KR20160117614A KR 20160117614 A KR20160117614 A KR 20160117614A KR 1020167025774 A KR1020167025774 A KR 1020167025774A KR 20167025774 A KR20167025774 A KR 20167025774A KR 20160117614 A KR20160117614 A KR 20160117614A
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compound
isomer
salt
pharmaceutically acceptable
acceptable salt
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Korean (ko)
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모하매드 레자 마세디자데
스티븐 고어레이
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프린시피아 바이오파마, 인코퍼레이티드
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Priority to KR1020227005455A priority Critical patent/KR20220027271A/ko
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/5395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more nitrogen atoms in the same ring, e.g. oxadiazines
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KR1020167025774A 2014-02-21 2015-02-20 Btk 억제제의 염 및 고체 형태 Ceased KR20160117614A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227005455A KR20220027271A (ko) 2014-02-21 2015-02-20 Btk 억제제의 염 및 고체 형태

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461943262P 2014-02-21 2014-02-21
US61/943,262 2014-02-21
US201461946480P 2014-02-28 2014-02-28
US61/946,480 2014-02-28
US201462096468P 2014-12-23 2014-12-23
US62/096,468 2014-12-23
PCT/US2015/016963 WO2015127310A1 (en) 2014-02-21 2015-02-20 Salts and solid form of a btk inhibitor

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KR1020227005455A Ceased KR20220027271A (ko) 2014-02-21 2015-02-20 Btk 억제제의 염 및 고체 형태

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US (5) US10092569B2 (cg-RX-API-DMAC7.html)
EP (2) EP3795158B1 (cg-RX-API-DMAC7.html)
JP (1) JP6504548B2 (cg-RX-API-DMAC7.html)
KR (2) KR20160117614A (cg-RX-API-DMAC7.html)
CN (2) CN106456652B (cg-RX-API-DMAC7.html)
AU (1) AU2015218713B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016018948B1 (cg-RX-API-DMAC7.html)
CA (1) CA2939186C (cg-RX-API-DMAC7.html)
EA (1) EA033900B1 (cg-RX-API-DMAC7.html)
ES (1) ES2841248T3 (cg-RX-API-DMAC7.html)
IL (2) IL247215B (cg-RX-API-DMAC7.html)
MX (1) MX372673B (cg-RX-API-DMAC7.html)
PT (1) PT3107544T (cg-RX-API-DMAC7.html)
SG (2) SG11201606858RA (cg-RX-API-DMAC7.html)
WO (1) WO2015127310A1 (cg-RX-API-DMAC7.html)
ZA (2) ZA201605933B (cg-RX-API-DMAC7.html)

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GB201410430D0 (en) 2014-06-11 2014-07-23 Redx Pharma Ltd Compounds
US9778212B2 (en) * 2014-10-31 2017-10-03 GM Global Technology Operations LLC Method for determining the lithiation of Li-ion battery electrodes
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JP7784995B2 (ja) * 2019-10-09 2025-12-12 プリンシピア バイオファーマ インコーポレイテッド （ｒ）－２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルを投与することによる天疱瘡を処置する方法
US20210106584A1 (en) 2019-10-14 2021-04-15 Principia Biopharma Inc. Methods for treating immune thrombocytopenia by administering (r)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
BR112022011516A2 (pt) * 2019-12-20 2022-08-23 Principia Biopharma Inc Formas sólidas de 2-[3-[4-amino-3-(2-flúor-4-fenóxi-fenil)pirazol[3,4-d]pirimidin-1-il]piperidina-1-carbonil]-4-metil-4-[4-(oxetan-3-il)piperazin-1-il]pent-2-enenitrila
CA3163278A1 (en) * 2020-01-06 2021-07-15 Philip Nunn Treatment of membranous nephropathy, igg4-related disease, and antiphospholipid syndrome using btk inhibitor 2-[(3r)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitril
MX2022008428A (es) * 2020-01-08 2022-08-08 Principia Biopharma Inc Composiciones farmaceuticas topicas que comprenden 2-[3-[4-amino-3-(2-fluoro-4-fenoxi-fenil)-1h-pirazolo[3,4-d]pirim idin-1-il]piperidina-1-carbonil]-4,4-dimetilpent-2-enonitrilo.
TW202140484A (zh) * 2020-01-22 2021-11-01 美商普林斯匹亞生物製藥公司 ２－［３－［４－胺基－３－（２－氟－４－苯氧基－苯基）－１Ｈ－吡唑并［３，４－ｄ］嘧啶－１－基］哌啶－１－羰基］－４－甲基－４－［４－（氧環丁烷－３－基）哌𠯤－１－基］戊－２－烯腈之晶形
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CN112353806A (zh) 2021-02-12
US11369613B2 (en) 2022-06-28
EP3107544B1 (en) 2020-10-07
WO2015127310A1 (en) 2015-08-27
EP3795158A1 (en) 2021-03-24
BR112016018948B1 (pt) 2023-01-17
US10828307B2 (en) 2020-11-10
IL275170A (en) 2020-07-30
US10092569B2 (en) 2018-10-09
IL247215A0 (en) 2016-09-29
KR20220027271A (ko) 2022-03-07
JP6504548B2 (ja) 2019-04-24
EP3107544A1 (en) 2016-12-28
US10456403B2 (en) 2019-10-29
ZA201905570B (en) 2021-02-24

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