KR20070100299A - 재조합 인간 성장 호르몬의 발현 및 정제 방법 - Google Patents

재조합 인간 성장 호르몬의 발현 및 정제 방법 Download PDF

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Publication number
KR20070100299A
KR20070100299A KR1020077016445A KR20077016445A KR20070100299A KR 20070100299 A KR20070100299 A KR 20070100299A KR 1020077016445 A KR1020077016445 A KR 1020077016445A KR 20077016445 A KR20077016445 A KR 20077016445A KR 20070100299 A KR20070100299 A KR 20070100299A
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South Korea
Prior art keywords
hgh
amino acid
amino acids
encoded amino
naturally encoded
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English (en)
Korean (ko)
Inventor
윙 뷰츨러
리키 리우
마이클 옹
스튜어트 버셀
닉 누센
호성 조
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암브룩스, 인코포레이티드
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Publication of KR20070100299A publication Critical patent/KR20070100299A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020077016445A 2004-12-22 2005-12-21 재조합 인간 성장 호르몬의 발현 및 정제 방법 Ceased KR20070100299A (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US63861604P 2004-12-22 2004-12-22
US60/638,616 2004-12-22
US65574405P 2005-02-23 2005-02-23
US60/655,744 2005-02-23
US68097705P 2005-05-13 2005-05-13
US60/680,977 2005-05-13
US72796805P 2005-10-17 2005-10-17
US60/727,968 2005-10-17

Publications (1)

Publication Number Publication Date
KR20070100299A true KR20070100299A (ko) 2007-10-10

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Family Applications (1)

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KR1020077016445A Ceased KR20070100299A (ko) 2004-12-22 2005-12-21 재조합 인간 성장 호르몬의 발현 및 정제 방법

Country Status (14)

Country Link
US (4) US8080391B2 (https=)
EP (1) EP1836316A4 (https=)
JP (1) JP2008525032A (https=)
KR (1) KR20070100299A (https=)
CN (1) CN103290084A (https=)
AU (2) AU2005323106B2 (https=)
BR (1) BRPI0518661A2 (https=)
CA (1) CA2590462C (https=)
GB (1) GB2438760A (https=)
IL (2) IL183344A (https=)
MX (1) MX2007007591A (https=)
NZ (1) NZ555206A (https=)
SG (1) SG161210A1 (https=)
WO (1) WO2006073846A2 (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
KR20150038715A (ko) * 2010-07-22 2015-04-08 바이오마린 파머수티컬 인크. 고도로 인산화된 활성 인간 n-아세틸갈락토사민-6-설파타제의 제조 및 이것의 용도

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AU2010236095A1 (en) 2010-11-18
EP1836316A4 (en) 2009-07-22
EP1836316A2 (en) 2007-09-26
CN103290084A (zh) 2013-09-11
US20080085538A1 (en) 2008-04-10
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US7959926B2 (en) 2011-06-14
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US8080391B2 (en) 2011-12-20
US20080199909A1 (en) 2008-08-21
US7947473B2 (en) 2011-05-24
US20080050777A1 (en) 2008-02-28
IL184154A0 (en) 2011-08-01

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