KR20070040824A - 아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용방법 - Google Patents

아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용방법 Download PDF

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Publication number
KR20070040824A
KR20070040824A KR1020077004986A KR20077004986A KR20070040824A KR 20070040824 A KR20070040824 A KR 20070040824A KR 1020077004986 A KR1020077004986 A KR 1020077004986A KR 20077004986 A KR20077004986 A KR 20077004986A KR 20070040824 A KR20070040824 A KR 20070040824A
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South Korea
Prior art keywords
antibody
region
peptide
seq
amino acid
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Ceased
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KR1020077004986A
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English (en)
Korean (ko)
Inventor
아논 로젠탈
자우메 폰즈
웨이-시엔 호
얀 마르쿠스 그림
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리나트 뉴로사이언스 코퍼레이션
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Publication of KR20070040824A publication Critical patent/KR20070040824A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020077004986A 2004-07-30 2005-08-01 아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용방법 Ceased KR20070040824A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US59249404P 2004-07-30 2004-07-30
US60/592,494 2004-07-30
US65319705P 2005-02-14 2005-02-14
US60/653,197 2005-02-14
US67609305P 2005-04-29 2005-04-29
US60/676,093 2005-04-29

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020097008841A Division KR101068289B1 (ko) 2004-07-30 2005-08-01 아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용 방법

Publications (1)

Publication Number Publication Date
KR20070040824A true KR20070040824A (ko) 2007-04-17

Family

ID=36010949

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020077004986A Ceased KR20070040824A (ko) 2004-07-30 2005-08-01 아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용방법
KR1020097008841A Expired - Fee Related KR101068289B1 (ko) 2004-07-30 2005-08-01 아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용 방법

Family Applications After (1)

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KR1020097008841A Expired - Fee Related KR101068289B1 (ko) 2004-07-30 2005-08-01 아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용 방법

Country Status (20)

Country Link
US (4) US7927594B2 (cg-RX-API-DMAC7.html)
EP (2) EP2298807A3 (cg-RX-API-DMAC7.html)
JP (2) JP5042828B2 (cg-RX-API-DMAC7.html)
KR (2) KR20070040824A (cg-RX-API-DMAC7.html)
AP (1) AP2007003890A0 (cg-RX-API-DMAC7.html)
AU (2) AU2005290250A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0513959A (cg-RX-API-DMAC7.html)
CA (1) CA2575663C (cg-RX-API-DMAC7.html)
EA (1) EA016357B1 (cg-RX-API-DMAC7.html)
GE (1) GEP20115195B (cg-RX-API-DMAC7.html)
IL (1) IL180364A (cg-RX-API-DMAC7.html)
MA (1) MA28757B1 (cg-RX-API-DMAC7.html)
MX (1) MX2007000998A (cg-RX-API-DMAC7.html)
NI (1) NI200700021A (cg-RX-API-DMAC7.html)
NO (1) NO20066058L (cg-RX-API-DMAC7.html)
NZ (1) NZ552480A (cg-RX-API-DMAC7.html)
SG (1) SG190665A1 (cg-RX-API-DMAC7.html)
TN (1) TNSN07031A1 (cg-RX-API-DMAC7.html)
TW (1) TWI355389B (cg-RX-API-DMAC7.html)
WO (1) WO2006036291A2 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190035948A (ko) * 2011-09-23 2019-04-03 에이씨 이뮨 에스.에이. 백신 요법

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