KR101549296B1 - 고역가 고순도 바이러스 스톡의 생산 방법 및 이의 사용 방법 - Google Patents
고역가 고순도 바이러스 스톡의 생산 방법 및 이의 사용 방법 Download PDFInfo
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- KR101549296B1 KR101549296B1 KR1020127029690A KR20127029690A KR101549296B1 KR 101549296 B1 KR101549296 B1 KR 101549296B1 KR 1020127029690 A KR1020127029690 A KR 1020127029690A KR 20127029690 A KR20127029690 A KR 20127029690A KR 101549296 B1 KR101549296 B1 KR 101549296B1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14351—Methods of production or purification of viral material
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32422010P | 2010-04-14 | 2010-04-14 | |
| US61/324,220 | 2010-04-14 | ||
| PCT/US2011/031747 WO2011130119A2 (en) | 2010-04-14 | 2011-04-08 | Methods of producing high titer, high purity virus stocks and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20130020954A KR20130020954A (ko) | 2013-03-04 |
| KR101549296B1 true KR101549296B1 (ko) | 2015-09-01 |
Family
ID=44148425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127029690A Expired - Fee Related KR101549296B1 (ko) | 2010-04-14 | 2011-04-08 | 고역가 고순도 바이러스 스톡의 생산 방법 및 이의 사용 방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9644187B2 (enExample) |
| EP (1) | EP2377927B1 (enExample) |
| JP (3) | JP2013523175A (enExample) |
| KR (1) | KR101549296B1 (enExample) |
| CN (1) | CN102985536B (enExample) |
| BR (1) | BR112012026095A2 (enExample) |
| ES (1) | ES2736166T3 (enExample) |
| SG (1) | SG184833A1 (enExample) |
| WO (1) | WO2011130119A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012026095A2 (pt) | 2010-04-14 | 2015-09-15 | Emd Millipore Corp | métodos de produção de estoques de vírus de alta pureza e altos títulos e métodos de uso dos mesmos. |
| DE102010046817A1 (de) * | 2010-09-28 | 2012-03-29 | Sartorius Stedim Biotech Gmbh | Verfahren zur Abtrennung von Viren aus einem Kontaminanten enthaltenden flüssigen Medium |
| CN104160019A (zh) * | 2012-03-13 | 2014-11-19 | Emd密理博公司 | 使用离心辅助的感染以增加病毒滴度 |
| CN104812893B (zh) * | 2012-11-22 | 2018-08-03 | 旭化成医疗株式会社 | 高感染滴度的细小病毒的生产方法 |
| EP2958995A4 (en) * | 2013-02-22 | 2016-11-23 | Agency Science Tech & Res | CHROMATOGRAPHIC CLEANING OF VIRUS PREPARATIONS WITH NEGATIVELY LOADED PARTICLES |
| DK3044339T3 (da) | 2013-09-10 | 2019-08-12 | MockV Solutions | Fremgangsmåder og sæt til kvantificering af fjernelsen af falske (MOCK) viruspartikler fra en renset opløsning |
| RU2701948C1 (ru) * | 2015-11-06 | 2019-10-02 | Асахи Касеи Медикал Ко., Лтд. | Способ получения парвовируса, характеризующегося высоким титром инфекционности и высокой чистотой |
| DE102016005049B4 (de) | 2016-04-26 | 2020-06-18 | Sartorius Stedim Biotech Gmbh | Verfahren zur Bestimmung des logarithmischen Reduktionswertes LRV eines Größenausschlussfilters |
| EP3299454A1 (en) * | 2016-09-21 | 2018-03-28 | Deutsches Krebsforschungszentrum | Optimized method for large scale production of parvovirus h-1 in an essentially serum-free medium |
| EP3141611A3 (en) | 2016-10-21 | 2017-05-10 | Bayer Healthcare LLC | Validation of continuous viral clearance |
| US10961512B2 (en) * | 2017-04-17 | 2021-03-30 | Dao-Yao He | Compositions and kits for purification of viral particles from host cells |
| KR102453351B1 (ko) * | 2017-07-05 | 2022-10-07 | 에스케이바이오사이언스(주) | 인플루엔자 백신용 바이러스 씨드 스톡의 제조 방법 |
| EP3446710A1 (en) * | 2017-08-25 | 2019-02-27 | Glenmark Pharmaceuticals S.A. | Methods of inactivating viral contaminants |
| CN108841794B (zh) * | 2018-06-08 | 2021-11-30 | 苏州良辰生物医药科技有限公司 | 一种病毒原液的制备方法 |
| JP7588466B2 (ja) * | 2020-01-22 | 2024-11-22 | 旭化成メディカル株式会社 | パルボウイルスの生産方法 |
| JP7390466B2 (ja) * | 2020-02-28 | 2023-12-01 | 旭化成メディカル株式会社 | ウイルスクリアランス性能の評価方法 |
| US12403428B2 (en) | 2020-06-24 | 2025-09-02 | Asahi Kasei Life Science Corporation | Evaluation method for protein-containing solution |
| CA3195893A1 (en) * | 2020-09-21 | 2022-03-24 | Bayer Healthcare Llc | Pathogen clearance system and method |
| US12203914B2 (en) | 2020-11-12 | 2025-01-21 | Sartorius Bioanalytical Instruments, Inc. | Viral clearance evaluation for biological medical product preparation processes |
| EP4317460A4 (en) | 2021-03-26 | 2024-10-23 | Asahi Kasei Medical Co., Ltd. | Viral clearance test method |
| WO2022252098A1 (zh) * | 2021-05-31 | 2022-12-08 | 中国科学院深圳先进技术研究院 | 噬菌体制剂的制备方法、药物组合物以及应用 |
| JP7665143B2 (ja) * | 2021-06-24 | 2025-04-21 | 株式会社島津製作所 | ウイルス試料の濃縮方法 |
Citations (2)
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|---|---|---|---|---|
| WO2007127264A2 (en) * | 2006-04-28 | 2007-11-08 | The Trustees Of The University Of Pennsylvania | Scalable production method for aav |
| WO2008026225A2 (en) * | 2006-09-01 | 2008-03-06 | Bharat Biotech International Limited | A vaccine for chikungunya virus infection |
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| KR101744430B1 (ko) | 2007-05-04 | 2017-06-20 | 백스터 인터내셔널 인코포레이티드 | 바이러스 정제를 위한 연속 초원심분리용 당 용액의 제조 |
| JP2011511640A (ja) * | 2008-02-12 | 2011-04-14 | サノフィ パストゥール リミテッド | ポックス・ウイルスの精製方法 |
| BR112012026095A2 (pt) | 2010-04-14 | 2015-09-15 | Emd Millipore Corp | métodos de produção de estoques de vírus de alta pureza e altos títulos e métodos de uso dos mesmos. |
| US9651469B1 (en) * | 2016-01-27 | 2017-05-16 | General Electric Company | Electrostatic particle sensor |
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2011
- 2011-04-08 BR BR112012026095A patent/BR112012026095A2/pt not_active IP Right Cessation
- 2011-04-08 WO PCT/US2011/031747 patent/WO2011130119A2/en not_active Ceased
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| WO2007127264A2 (en) * | 2006-04-28 | 2007-11-08 | The Trustees Of The University Of Pennsylvania | Scalable production method for aav |
| WO2008026225A2 (en) * | 2006-09-01 | 2008-03-06 | Bharat Biotech International Limited | A vaccine for chikungunya virus infection |
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| Bio/Technology. 1993, vol. 11, pages 173-178. |
| BioProcess International. 2005, vol. 3, no. 10, Supplement, pages 39-43.* |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6522054B2 (ja) | 2019-05-29 |
| US20120088228A1 (en) | 2012-04-12 |
| JP2013523175A (ja) | 2013-06-17 |
| SG184833A1 (en) | 2012-11-29 |
| JP2015126757A (ja) | 2015-07-09 |
| CN102985536B (zh) | 2017-12-05 |
| US9644187B2 (en) | 2017-05-09 |
| WO2011130119A3 (en) | 2012-03-29 |
| KR20130020954A (ko) | 2013-03-04 |
| WO2011130119A8 (en) | 2011-12-29 |
| EP2377927A1 (en) | 2011-10-19 |
| CN102985536A (zh) | 2013-03-20 |
| BR112012026095A2 (pt) | 2015-09-15 |
| JP6284500B2 (ja) | 2018-02-28 |
| ES2736166T3 (es) | 2019-12-26 |
| EP2377927B1 (en) | 2019-05-22 |
| WO2011130119A2 (en) | 2011-10-20 |
| JP2017195897A (ja) | 2017-11-02 |
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