KR101549296B1 - 고역가 고순도 바이러스 스톡의 생산 방법 및 이의 사용 방법 - Google Patents

고역가 고순도 바이러스 스톡의 생산 방법 및 이의 사용 방법 Download PDF

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KR101549296B1
KR101549296B1 KR1020127029690A KR20127029690A KR101549296B1 KR 101549296 B1 KR101549296 B1 KR 101549296B1 KR 1020127029690 A KR1020127029690 A KR 1020127029690A KR 20127029690 A KR20127029690 A KR 20127029690A KR 101549296 B1 KR101549296 B1 KR 101549296B1
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KR20130020954A (ko
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다몬 알. 아셔
아만다 비. 카츠
나비드 제트. 칸
우쉬마 메타
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이엠디 밀리포어 코포레이션
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice
    • C12N2750/14351—Methods of production or purification of viral material

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  • Life Sciences & Earth Sciences (AREA)
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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
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  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020127029690A 2010-04-14 2011-04-08 고역가 고순도 바이러스 스톡의 생산 방법 및 이의 사용 방법 Expired - Fee Related KR101549296B1 (ko)

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US32422010P 2010-04-14 2010-04-14
US61/324,220 2010-04-14
PCT/US2011/031747 WO2011130119A2 (en) 2010-04-14 2011-04-08 Methods of producing high titer, high purity virus stocks and methods of use thereof

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KR20130020954A KR20130020954A (ko) 2013-03-04
KR101549296B1 true KR101549296B1 (ko) 2015-09-01

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US (1) US9644187B2 (enExample)
EP (1) EP2377927B1 (enExample)
JP (3) JP2013523175A (enExample)
KR (1) KR101549296B1 (enExample)
CN (1) CN102985536B (enExample)
BR (1) BR112012026095A2 (enExample)
ES (1) ES2736166T3 (enExample)
SG (1) SG184833A1 (enExample)
WO (1) WO2011130119A2 (enExample)

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WO2017077804A1 (ja) * 2015-11-06 2017-05-11 旭化成メディカル株式会社 高感染価かつ高純度のパルボウイルスの生産方法
DE102016005049B4 (de) 2016-04-26 2020-06-18 Sartorius Stedim Biotech Gmbh Verfahren zur Bestimmung des logarithmischen Reduktionswertes LRV eines Größenausschlussfilters
EP3299454A1 (en) * 2016-09-21 2018-03-28 Deutsches Krebsforschungszentrum Optimized method for large scale production of parvovirus h-1 in an essentially serum-free medium
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US10961512B2 (en) * 2017-04-17 2021-03-30 Dao-Yao He Compositions and kits for purification of viral particles from host cells
KR102453351B1 (ko) 2017-07-05 2022-10-07 에스케이바이오사이언스(주) 인플루엔자 백신용 바이러스 씨드 스톡의 제조 방법
EP3446710A1 (en) * 2017-08-25 2019-02-27 Glenmark Pharmaceuticals S.A. Methods of inactivating viral contaminants
CN108841794B (zh) * 2018-06-08 2021-11-30 苏州良辰生物医药科技有限公司 一种病毒原液的制备方法
JP7588466B2 (ja) * 2020-01-22 2024-11-22 旭化成メディカル株式会社 パルボウイルスの生産方法
US20230103302A1 (en) * 2020-02-28 2023-04-06 Asahi Kasei Medical Co., Ltd. Method for evaluating viral clearance capability
EP4173696A4 (en) * 2020-06-24 2023-12-20 Asahi Kasei Medical Co., Ltd. METHOD FOR EVALUATING A SOLUTION CONTAINING PROTEINS
JP7756155B2 (ja) * 2020-09-21 2025-10-17 バイエル・ヘルスケア・エルエルシー 病原体クリアランスシステムおよび方法
US12203914B2 (en) 2020-11-12 2025-01-21 Sartorius Bioanalytical Instruments, Inc. Viral clearance evaluation for biological medical product preparation processes
EP4317460A4 (en) 2021-03-26 2024-10-23 Asahi Kasei Medical Co., Ltd. Viral clearance test method
WO2022252098A1 (zh) * 2021-05-31 2022-12-08 中国科学院深圳先进技术研究院 噬菌体制剂的制备方法、药物组合物以及应用
JP7665143B2 (ja) * 2021-06-24 2025-04-21 株式会社島津製作所 ウイルス試料の濃縮方法

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JP2017195897A (ja) 2017-11-02
ES2736166T3 (es) 2019-12-26
CN102985536B (zh) 2017-12-05
SG184833A1 (en) 2012-11-29
JP6284500B2 (ja) 2018-02-28
BR112012026095A2 (pt) 2015-09-15
WO2011130119A2 (en) 2011-10-20
JP6522054B2 (ja) 2019-05-29
KR20130020954A (ko) 2013-03-04
JP2015126757A (ja) 2015-07-09
EP2377927B1 (en) 2019-05-22
US9644187B2 (en) 2017-05-09
EP2377927A1 (en) 2011-10-19
CN102985536A (zh) 2013-03-20
WO2011130119A8 (en) 2011-12-29
JP2013523175A (ja) 2013-06-17
US20120088228A1 (en) 2012-04-12
WO2011130119A3 (en) 2012-03-29

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