KR101442846B1 - 톨 유사 수용체 조절제로서의 8-치환된 벤조아제핀 - Google Patents

톨 유사 수용체 조절제로서의 8-치환된 벤조아제핀 Download PDF

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KR101442846B1
KR101442846B1 KR1020087006590A KR20087006590A KR101442846B1 KR 101442846 B1 KR101442846 B1 KR 101442846B1 KR 1020087006590 A KR1020087006590 A KR 1020087006590A KR 20087006590 A KR20087006590 A KR 20087006590A KR 101442846 B1 KR101442846 B1 KR 101442846B1
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alkyl
phenyl
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KR20080038413A (ko
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조지 에이. 도허티
씨. 토드 얼리
로버트 디. 그로네버그
자카리 존스
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어레이 바이오파마 인크.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
KR1020087006590A 2005-08-19 2006-08-17 톨 유사 수용체 조절제로서의 8-치환된 벤조아제핀 Expired - Fee Related KR101442846B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71000405P 2005-08-19 2005-08-19
US60/710,004 2005-08-19
PCT/US2006/032098 WO2007024612A2 (en) 2005-08-19 2006-08-17 8-substituted benzoazepines as toll-like receptor modulators

Related Child Applications (1)

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KR1020137016949A Division KR20130082182A (ko) 2005-08-19 2006-08-17 톨 유사 수용체 조절제로서의 8-치환된 벤조아제핀

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KR20080038413A KR20080038413A (ko) 2008-05-06
KR101442846B1 true KR101442846B1 (ko) 2014-10-01

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KR1020087006590A Expired - Fee Related KR101442846B1 (ko) 2005-08-19 2006-08-17 톨 유사 수용체 조절제로서의 8-치환된 벤조아제핀
KR1020137016949A Withdrawn KR20130082182A (ko) 2005-08-19 2006-08-17 톨 유사 수용체 조절제로서의 8-치환된 벤조아제핀

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US (2) US8153622B2 (https=)
EP (3) EP3081558A1 (https=)
JP (1) JP5138592B2 (https=)
KR (2) KR101442846B1 (https=)
CN (6) CN104910072A (https=)
AP (1) AP2008004386A0 (https=)
AU (1) AU2006283620B2 (https=)
BR (1) BRPI0614941B8 (https=)
CA (3) CA2619581C (https=)
CR (2) CR9809A (https=)
DK (1) DK1940797T3 (https=)
EA (1) EA018543B1 (https=)
EC (1) ECSP088292A (https=)
ES (1) ES2391031T3 (https=)
HR (1) HRP20120695T1 (https=)
IL (2) IL189467A (https=)
MA (1) MA29838B1 (https=)
MX (1) MX2008002141A (https=)
MY (1) MY146567A (https=)
NO (1) NO342587B1 (https=)
NZ (1) NZ565907A (https=)
PL (1) PL1940797T3 (https=)
PT (1) PT1940797E (https=)
RS (1) RS52447B (https=)
SI (1) SI1940797T1 (https=)
TN (1) TNSN08076A1 (https=)
TW (2) TW201402124A (https=)
UA (1) UA92754C2 (https=)
WO (1) WO2007024612A2 (https=)
ZA (1) ZA200802496B (https=)

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EP2322510A2 (en) 2011-05-18
CN109096193A (zh) 2018-12-28
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SI1940797T1 (sl) 2012-11-30
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RS52447B (sr) 2013-02-28
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