KR101246243B1 - 에틸렌옥사이드 부틸렌옥사이드 블록 코폴리머를 포함하는 안과용 조성물 - Google Patents

에틸렌옥사이드 부틸렌옥사이드 블록 코폴리머를 포함하는 안과용 조성물 Download PDF

Info

Publication number
KR101246243B1
KR101246243B1 KR1020127003060A KR20127003060A KR101246243B1 KR 101246243 B1 KR101246243 B1 KR 101246243B1 KR 1020127003060 A KR1020127003060 A KR 1020127003060A KR 20127003060 A KR20127003060 A KR 20127003060A KR 101246243 B1 KR101246243 B1 KR 101246243B1
Authority
KR
South Korea
Prior art keywords
composition
compositions
guar
block copolymer
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020127003060A
Other languages
English (en)
Korean (ko)
Other versions
KR20120028994A (ko
Inventor
제임스 더블유. 데이비스
하워드 알렌 케텔슨
데이비드 엘. 미도우즈
Original Assignee
알콘 리서치, 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 알콘 리서치, 리미티드 filed Critical 알콘 리서치, 리미티드
Publication of KR20120028994A publication Critical patent/KR20120028994A/ko
Application granted granted Critical
Publication of KR101246243B1 publication Critical patent/KR101246243B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/77Polymers containing oxygen of oxiranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/008Polymeric surface-active agents
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/20Organic compounds containing oxygen
    • C11D3/22Carbohydrates or derivatives thereof
    • C11D3/222Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Eyeglasses (AREA)
KR1020127003060A 2009-07-07 2010-07-07 에틸렌옥사이드 부틸렌옥사이드 블록 코폴리머를 포함하는 안과용 조성물 Expired - Fee Related KR101246243B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22359909P 2009-07-07 2009-07-07
US61/223,599 2009-07-07
PCT/US2010/041218 WO2011005864A2 (en) 2009-07-07 2010-07-07 Ethyleneoxide butyleneoxide block copolymer compositions

Publications (2)

Publication Number Publication Date
KR20120028994A KR20120028994A (ko) 2012-03-23
KR101246243B1 true KR101246243B1 (ko) 2013-03-22

Family

ID=43427630

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127003060A Expired - Fee Related KR101246243B1 (ko) 2009-07-07 2010-07-07 에틸렌옥사이드 부틸렌옥사이드 블록 코폴리머를 포함하는 안과용 조성물

Country Status (15)

Country Link
US (1) US9175249B2 (enExample)
EP (1) EP2451463B1 (enExample)
JP (1) JP5791600B2 (enExample)
KR (1) KR101246243B1 (enExample)
CN (1) CN102548561B (enExample)
AR (1) AR077458A1 (enExample)
AU (1) AU2010270628B2 (enExample)
BR (1) BR112012000506A2 (enExample)
CA (1) CA2767459C (enExample)
CL (1) CL2012000061A1 (enExample)
MX (1) MX2012000456A (enExample)
RU (1) RU2548789C2 (enExample)
TW (1) TWI547522B (enExample)
WO (1) WO2011005864A2 (enExample)
ZA (1) ZA201200255B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2664053T3 (es) * 2012-11-19 2018-04-18 Bausch & Lomb Incorporated Composición líquida acuosa que contiene ácido 2-amino-3-(4-bromobenzoil)fenil-láctico
JP6325657B2 (ja) * 2013-09-27 2018-05-16 ノバルティス アーゲー コンタクトレンズを消毒及び洗浄するための組成物及び方法
US9987581B2 (en) 2015-06-22 2018-06-05 Agco International Gmbh Vehicle filter system
AU2017316997B2 (en) * 2016-08-24 2022-06-30 Royal Melbourne Institute Of Technology Diagnostic methods and device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100379881B1 (ko) * 1997-07-29 2003-04-14 알콘 래보레이토리스, 인코퍼레이티드 하드 콘택트 렌즈 보호용 컨디셔닝 용액
US20080138310A1 (en) * 2006-12-11 2008-06-12 Alcon Manufacturing, Ltd. Use of PEO-PBO block copolymers in ophthalmic compositions

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2174761A (en) * 1935-04-13 1939-10-03 Ig Farbenindustrie Ag Condensation products derived from hydroxy compounds and method of producing them
GB722746A (en) 1952-06-24 1955-01-26 Wyandotte Chemicals Corp Surface active compounds derived from higher ª‡, ª‰ alkylene oxides
US2674619A (en) * 1953-10-19 1954-04-06 Wyandotte Chemicals Corp Polyoxyalkylene compounds
US2828345A (en) * 1955-04-27 1958-03-25 Dow Chemical Co Hydroxypolyoxyethylene diethers of polyoxybutylene glycols
US3050511A (en) * 1958-09-15 1962-08-21 Dow Chemical Co Block copolymers of alkenyl aromatic hydrocarbons and alkylene oxides
US3042668A (en) * 1960-12-02 1962-07-03 American Molasses Company Modified galactomannan gums and method of preparing same
US3829506A (en) * 1971-06-01 1974-08-13 Basf Wyandotte Corp Biodegradable surface active agents having good foam properties and foam stabilizing characteristics
US4130517A (en) * 1973-01-29 1978-12-19 Exxon Research & Engineering Co. Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains
CA1043039A (en) * 1973-01-29 1978-11-21 Robert D. Lundberg Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains
US4104824A (en) * 1975-02-27 1978-08-08 Exxon Research & Engineering Co. Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains
US4218327A (en) * 1976-04-05 1980-08-19 Shell Oil Company Stabilizing the viscosity of an aqueous solution of polysaccharide polymer
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
JPS5594901A (en) 1979-01-11 1980-07-18 Nichiden Kagaku Kk Preparation of modified guar gum
US4360451A (en) * 1981-08-10 1982-11-23 Basf Wyandotte Corporation Amphoteric surfactant gels
US4447336A (en) * 1981-12-18 1984-05-08 Monsanto Company Stabilized galactomannan gum compositions
US4447337A (en) * 1982-02-24 1984-05-08 Monsanto Company Stabiized galactomannan gum compositions
US4606831A (en) * 1985-06-17 1986-08-19 Monsanto Company Stabilized galactomannan gum compositions
SE458576B (sv) * 1985-06-20 1989-04-17 Lejus Medical Ab Foerfarande foer framstaellning av en guar-gum produkt
JPS6335606A (ja) 1986-07-30 1988-02-16 Mitsubishi Acetate Co Ltd ガラクトマンナンの精製方法
JPS63101402A (ja) 1986-10-17 1988-05-06 Mitsubishi Acetate Co Ltd ガラクトマンナンの精製法
DE3701509A1 (de) 1987-01-21 1988-08-04 Henkel Kgaa Verfahren zur herstellung von guar-(misch-)ethern aus guarsplits
EP0323798A3 (en) * 1987-12-02 1991-07-03 Colgate-Palmolive Company Mild cleansing and conditioning composition to yield a soft, smooth skin
JPH01247049A (ja) 1988-03-29 1989-10-02 Sumitomo Chem Co Ltd 溶解性の改良されたガラクトマンナンの製造法
US5037647A (en) * 1988-09-15 1991-08-06 Alcon Laboratories, Inc. Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride
ATE124963T1 (de) * 1988-09-22 1995-07-15 Univ Utah Superoberflächenaktive polymermittel zur verleihung eines widerstandes gegen proteine und zur eliminierung von proteinen.
US5233032A (en) * 1990-06-29 1993-08-03 Stein, Hall & Co., Inc. Hydrophobically modified hydroxybutyl ethers of polygalactomannan
US5077033A (en) * 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
US5376693A (en) * 1990-08-07 1994-12-27 Mediventures Inc. Thermo-irreversible gel corneal contact lens formed in situ
US5346703A (en) * 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
JPH08842B2 (ja) 1991-05-22 1996-01-10 信越化学工業株式会社 多糖類の精製方法
EP0557627A1 (en) 1992-02-24 1993-09-01 TAIYO KAGAKU Co., LTD. Limitedly enzyme-hydrolyzed polysaccharide and method for its production
JP2729722B2 (ja) 1992-03-02 1998-03-18 三菱レイヨン株式会社 精製ガラクトマンナンの製造方法
JPH05239105A (ja) 1992-03-02 1993-09-17 Mitsubishi Rayon Co Ltd 精製ガラクトマンナンの製造方法
US5505953A (en) * 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
DE69333850T3 (de) * 1992-05-06 2011-03-17 Alcon Laboratories, Inc., Fort Worth Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen
CN1128867C (zh) * 1993-06-18 2003-11-26 聚合物技术公司 清洗和润湿隐形眼镜的组合物
US5370744B1 (en) * 1993-08-27 1999-11-09 Alcon Lab Inc Process for cleaning and disinfecting contact lenses
US5631005A (en) * 1994-09-21 1997-05-20 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5489674A (en) * 1994-06-09 1996-02-06 Rhone-Poulenc Inc. Guar gum composition and process for making it
US5536825A (en) * 1994-06-09 1996-07-16 Rhone-Poulenc Inc. Derivatized guar gum composition and process for making it
DE69521170T2 (de) 1994-06-09 2001-10-04 Rhodia Inc., Cranbury Guargummizusammensetzung und Verfahren zur deren Herstellung
ES2163462T3 (es) * 1994-08-22 2002-02-01 Kao Corp Composicion detergente para superficie dura.
US5602241A (en) 1995-03-14 1997-02-11 Shin-Etsu Chemical Co., Ltd. Method for purifying polysaccharides
US6063402A (en) * 1995-06-07 2000-05-16 Venture Lending, A Division Of Cupertino National Bank Purified galactomannan as an improved pharmaceutical excipient
CH691026A5 (de) 1995-09-28 2001-04-12 Meyhall Chemical Ag Rhone Poul Verfahren zur Herstellung von reinem Guarkernmehl.
WO1997016408A1 (de) * 1995-10-27 1997-05-09 Basf Aktiengesellschaft Fettsäurederivate und ihre verwendung als tenside in wasch- und reinigungsmitteln
JP4030603B2 (ja) * 1995-11-02 2008-01-09 ノボザイムス アクティーゼルスカブ アルカリプロテアーゼ、その製造方法、用途及びそのプロテアーゼを生産する微生物
CA2242239A1 (en) 1996-01-05 1997-07-17 Rhone-Poulenc Inc. Modified guar, prepared by high shear treatment under acidic conditions at elevated temperature
US5756720A (en) * 1996-10-25 1998-05-26 Rhodia Inc. Derivatized guar gum composition including nonionic and cationic groups which demonstrate excellent solution clarity properties
ATE230764T1 (de) 1996-10-25 2003-01-15 Rhodia Zusammensetzung auf basis von derivatisiertem guargummi, welche nichtionische und kationische gruppen enthält, und die daraus hergestellten lösungen sehr klar und in reinigungsmitteln verwendbar sind
WO1998025649A1 (en) * 1996-12-13 1998-06-18 Alcon Laboratories, Inc. Use of low molecular weight amino alcohols in ophthalmic compositions
US6214596B1 (en) * 1996-12-18 2001-04-10 Alcon Laboratories, Inc. Liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5997907A (en) * 1997-03-12 1999-12-07 Rhodia Inc. Enhancement of guar solution stability
CN100408100C (zh) * 1997-07-29 2008-08-06 阿尔康实验室公司 含半乳甘露聚糖聚合物和硼酸盐的眼用组合物
ZA9811445B (en) * 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
US6656504B1 (en) * 1999-09-09 2003-12-02 Elan Pharma International Ltd. Nanoparticulate compositions comprising amorphous cyclosporine and methods of making and using such compositions
MY128134A (en) * 2000-09-28 2007-01-31 Novartis Ag Compositions and methods for cleaning contact lenses
EP1390085B1 (en) * 2001-05-01 2009-08-05 A.V. Topchiev Institute of Petrochemical Synthesis Hydrogel compositions
DE10135060A1 (de) 2001-07-18 2003-02-06 Noveon Ip Holdings Corp Galactomannan mit verändertem Mannose zu Galactose Verhältnis
TW200300448A (en) 2001-11-21 2003-06-01 Novartis Ag Conditioning solution for contact lenses
DE10241878A1 (de) * 2002-09-10 2004-03-11 Ecolab Gmbh & Co. Ohg Reinigung von Fahrzeugen
US20040241130A1 (en) * 2002-09-13 2004-12-02 Krishnan Tamareselvy Multi-purpose polymers, methods and compositions
US7378479B2 (en) * 2002-09-13 2008-05-27 Lubrizol Advanced Materials, Inc. Multi-purpose polymers, methods and compositions
ITTO20020809A1 (it) * 2002-09-17 2004-03-18 St Microelectronics Srl Micropompa, in particolare per un dispositivo integrato di analisi del dna.
TW200503762A (en) 2003-05-09 2005-02-01 Toho Chem Ind Co Ltd Cation-modified galactomannan polysaccharide and cosmetic composition containing the same
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7195065B2 (en) * 2004-08-05 2007-03-27 Baker Hughes Incorporated Stabilizing crosslinked polymer guars and modified guar derivatives
US7629386B2 (en) * 2004-08-26 2009-12-08 Bausch + Lomb Incorporated Compositions containing trialkanolamine alkoxylate buffer
RU2285511C2 (ru) * 2004-10-13 2006-10-20 НИИ ГБ им. Гельмгольца Средство для лечения синдрома сухого глаза
US20060229219A1 (en) * 2005-04-11 2006-10-12 Advanced Medical Optics, Inc. Borate-polyol mixtures as a buffering system
US7282178B2 (en) * 2005-06-03 2007-10-16 Bausch & Lomb Incorporated Composition and method for cleaning lipid deposits on contact lenses
TW200904485A (en) * 2007-05-18 2009-02-01 Alcon Res Ltd Phospholipid compositions for contact lens care and preservation of pharmaceutical compositions
US20090132294A1 (en) * 2007-11-15 2009-05-21 Haines Samuel H Method for ranking driver's relative risk based on reported driving incidents
MX2010011736A (es) * 2008-04-26 2011-01-21 Alcon Res Ltd Sistema polimérico de lágrimas artificiales.
KR20110095857A (ko) 2008-09-10 2011-08-25 칼립시스, 인코포레이티드 질환의 치료를 위한 히스타민 수용체의 헤테로시클릭 억제제

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100379881B1 (ko) * 1997-07-29 2003-04-14 알콘 래보레이토리스, 인코퍼레이티드 하드 콘택트 렌즈 보호용 컨디셔닝 용액
US20080138310A1 (en) * 2006-12-11 2008-06-12 Alcon Manufacturing, Ltd. Use of PEO-PBO block copolymers in ophthalmic compositions

Also Published As

Publication number Publication date
US20110008276A1 (en) 2011-01-13
TWI547522B (zh) 2016-09-01
CA2767459C (en) 2018-04-10
AR077458A1 (es) 2011-08-31
AU2010270628A1 (en) 2012-02-02
WO2011005864A2 (en) 2011-01-13
RU2548789C2 (ru) 2015-04-20
BR112012000506A2 (pt) 2017-05-16
CN102548561B (zh) 2016-03-16
CN102548561A (zh) 2012-07-04
MX2012000456A (es) 2012-02-28
WO2011005864A3 (en) 2011-04-28
EP2451463B1 (en) 2018-11-07
US9175249B2 (en) 2015-11-03
TW201107414A (en) 2011-03-01
CL2012000061A1 (es) 2012-10-19
JP2012532878A (ja) 2012-12-20
JP5791600B2 (ja) 2015-10-07
ZA201200255B (en) 2013-03-27
RU2012103982A (ru) 2013-08-20
CA2767459A1 (en) 2011-01-13
EP2451463A2 (en) 2012-05-16
AU2010270628B2 (en) 2013-12-19
KR20120028994A (ko) 2012-03-23

Similar Documents

Publication Publication Date Title
JP6130741B2 (ja) ソフトコンタクトレンズ用眼科組成物
EP2437723B1 (en) Omega-3 oil containing ophthalmic emulsions
CN101594779B (zh) 具有较少端胺基的双胍组合物
AU2009240488B2 (en) Polymeric artificial tear system
JP5401043B2 (ja) 眼科用組成物
JP6452283B2 (ja) 眼の異物感改善剤
KR101246243B1 (ko) 에틸렌옥사이드 부틸렌옥사이드 블록 코폴리머를 포함하는 안과용 조성물
US20080020017A1 (en) Intraocular Irrigating Solution Having Improved Flow Characteristics
US7084130B2 (en) Intraocular irrigating solution having improved flow characteristics
AU2014209426B2 (en) Poly(nitrogen/amine) derivatives of a natural wax and ophthalmic compositions
JP6177594B2 (ja) 水性眼科組成物
JP2012056875A (ja) ソフトコンタクトレンズ用眼科組成物
US20230310615A1 (en) Ophthalmic compositions
CN111050777A (zh) 提供改善的眼睛舒适度的组合物
RU2806029C2 (ru) Композиции, обеспечивающие повышенный комфорт для глаз
EP3827818A1 (en) Ophthalmic composition
JP2021102570A (ja) 眼科用組成物及び外観安定化方法
JP2019081801A (ja) シリコーンハイドロゲルコンタクトレンズ用眼科組成物
US20090258955A1 (en) Intraocular irrigating solution having improved flow characteristics
JP2019048799A (ja) 眼科用組成物及び涙液油層安定化剤
JP2019218270A (ja) 眼科用組成物及び消泡促進方法

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

A302 Request for accelerated examination
PA0302 Request for accelerated examination

St.27 status event code: A-1-2-D10-D17-exm-PA0302

St.27 status event code: A-1-2-D10-D16-exm-PA0302

D13-X000 Search requested

St.27 status event code: A-1-2-D10-D13-srh-X000

D14-X000 Search report completed

St.27 status event code: A-1-2-D10-D14-srh-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E601 Decision to refuse application
PE0601 Decision on rejection of patent

St.27 status event code: N-2-6-B10-B15-exm-PE0601

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PX0901 Re-examination

St.27 status event code: A-2-3-E10-E12-rex-PX0901

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PX0701 Decision of registration after re-examination

St.27 status event code: A-3-4-F10-F13-rex-PX0701

X701 Decision to grant (after re-examination)
GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20160218

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

FPAY Annual fee payment

Payment date: 20170302

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20180316

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20180316