KR100826817B1 - 치환된 베타-카볼린 - Google Patents

치환된 베타-카볼린 Download PDF

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Publication number
KR100826817B1
KR100826817B1 KR1020027012072A KR20027012072A KR100826817B1 KR 100826817 B1 KR100826817 B1 KR 100826817B1 KR 1020027012072 A KR1020027012072 A KR 1020027012072A KR 20027012072 A KR20027012072 A KR 20027012072A KR 100826817 B1 KR100826817 B1 KR 100826817B1
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South Korea
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alkyl
phenyl
independently
substituents
substituted
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Expired - Fee Related
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Korean (ko)
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KR20020080000A (ko
Inventor
리첼러올라프
캐스트로알프레도
그레니어루이스
수시프랑소와
핸콕웨인더블류.
마지야스니호르모츠
팔롬벨라비토
아담스줄리안
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사노피-아벤티스 도이칠란트 게엠베하
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Priority claimed from EP00105514A external-priority patent/EP1134221A1/en
Priority claimed from EP00125169A external-priority patent/EP1209158A1/en
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Publication of KR20020080000A publication Critical patent/KR20020080000A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Health & Medical Sciences (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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  • AIDS & HIV (AREA)
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KR1020027012072A 2000-03-15 2001-02-28 치환된 베타-카볼린 Expired - Fee Related KR100826817B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP00105514.4 2000-03-15
EP00105514A EP1134221A1 (en) 2000-03-15 2000-03-15 Substituted beta-carbolines as lkB kinase inhibitors
EP00125169.3 2000-11-18
EP00125169A EP1209158A1 (en) 2000-11-18 2000-11-18 Substituted beta-carbolines

Publications (2)

Publication Number Publication Date
KR20020080000A KR20020080000A (ko) 2002-10-21
KR100826817B1 true KR100826817B1 (ko) 2008-05-02

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US (3) US6627637B2 (https=)
JP (1) JP5000828B2 (https=)
KR (1) KR100826817B1 (https=)
CN (1) CN100509810C (https=)
AT (1) ATE465161T1 (https=)
AU (2) AU3741801A (https=)
BR (1) BR0109161A (https=)
CA (1) CA2402549A1 (https=)
CZ (1) CZ301077B6 (https=)
DE (1) DE60141895D1 (https=)
EE (1) EE200200523A (https=)
HK (1) HK1054039B (https=)
HR (1) HRP20020748A2 (https=)
HU (1) HUP0300894A3 (https=)
IL (2) IL151695A0 (https=)
ME (1) MEP28108A (https=)
MX (1) MXPA02007981A (https=)
NO (1) NO324248B1 (https=)
NZ (1) NZ521386A (https=)
PL (1) PL357284A1 (https=)
RU (1) RU2277095C2 (https=)
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Publication number Priority date Publication date Assignee Title
HUP0300894A3 (en) * 2000-03-15 2008-05-28 Sanofi Aventis Deutschland Substituted beta-carbolines, process for their preparation, pharmaceutical compositions containing them and their use
MXPA03006817A (es) * 2001-02-01 2003-11-13 Bristol Myers Squibb Co Metodo de tratamiento de enfermedades inflamatorias e inmunes usando inhibidores de la ikb cinasa (ikk).
DE60217532T8 (de) * 2001-11-07 2008-02-07 Millennium Pharmaceuticals, Inc., Cambridge Carboline derivate als ikb-inhibitoren zur behandlung des m ultiplen myelomas
US7462638B2 (en) * 2002-08-17 2008-12-09 Sanofi-Aventis Deutschland Gmbh Use of IκB-kinase inhibitors in pain therapy
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