KR100443306B1 - 사이클로스포린 또는 마크롤라이드를 포함하는 에멀젼예비농축물 - Google Patents

사이클로스포린 또는 마크롤라이드를 포함하는 에멀젼예비농축물 Download PDF

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Publication number
KR100443306B1
KR100443306B1 KR10-2000-7009861A KR20007009861A KR100443306B1 KR 100443306 B1 KR100443306 B1 KR 100443306B1 KR 20007009861 A KR20007009861 A KR 20007009861A KR 100443306 B1 KR100443306 B1 KR 100443306B1
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South Korea
Prior art keywords
composition
component
fatty acid
weight
cyclosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR10-2000-7009861A
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English (en)
Korean (ko)
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KR20010041657A (ko
Inventor
앰부흘미쉘
룩켈바르바라
리흐터프리드리히
하버린바르바라
마인저아민
Original Assignee
노바티스 아게
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27269231&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100443306(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9804742.6A external-priority patent/GB9804742D0/en
Priority claimed from GBGB9805104.8A external-priority patent/GB9805104D0/en
Priority claimed from GBGB9805199.8A external-priority patent/GB9805199D0/en
Application filed by 노바티스 아게 filed Critical 노바티스 아게
Publication of KR20010041657A publication Critical patent/KR20010041657A/ko
Application granted granted Critical
Publication of KR100443306B1 publication Critical patent/KR100443306B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR10-2000-7009861A 1998-03-06 1999-03-04 사이클로스포린 또는 마크롤라이드를 포함하는 에멀젼예비농축물 Expired - Fee Related KR100443306B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9804742.6 1998-03-06
GBGB9804742.6A GB9804742D0 (en) 1998-03-06 1998-03-06 Organic compounds
GB9805104.8 1998-03-10
GBGB9805104.8A GB9805104D0 (en) 1998-03-10 1998-03-10 Organic compounds
GB9805199.8 1998-03-11
GBGB9805199.8A GB9805199D0 (en) 1998-03-11 1998-03-11 Organic compounds

Publications (2)

Publication Number Publication Date
KR20010041657A KR20010041657A (ko) 2001-05-25
KR100443306B1 true KR100443306B1 (ko) 2004-08-09

Family

ID=27269231

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2000-7009861A Expired - Fee Related KR100443306B1 (ko) 1998-03-06 1999-03-04 사이클로스포린 또는 마크롤라이드를 포함하는 에멀젼예비농축물

Country Status (29)

Country Link
EP (2) EP1059913B1 (enExample)
JP (2) JP2002505271A (enExample)
KR (1) KR100443306B1 (enExample)
CN (1) CN1195495C (enExample)
AR (1) AR015729A1 (enExample)
AT (1) ATE277599T1 (enExample)
AU (1) AU749217B2 (enExample)
BE (3) BE1012400A5 (enExample)
BR (1) BR9908597A (enExample)
CA (1) CA2322845C (enExample)
CO (1) CO4930289A1 (enExample)
CZ (1) CZ301967B6 (enExample)
DE (2) DE69920668T2 (enExample)
ES (1) ES2228014T3 (enExample)
FR (4) FR2775596B1 (enExample)
GB (1) GB2350791B (enExample)
HU (1) HUP0101080A3 (enExample)
ID (1) ID25908A (enExample)
IL (2) IL138248A0 (enExample)
IT (1) IT1313550B1 (enExample)
MY (1) MY129274A (enExample)
NO (1) NO331800B1 (enExample)
NZ (1) NZ506644A (enExample)
PE (1) PE20000324A1 (enExample)
PT (1) PT1059913E (enExample)
SK (1) SK285139B6 (enExample)
TR (1) TR200002586T2 (enExample)
TW (3) TWI236912B (enExample)
WO (1) WO1999044584A1 (enExample)

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US8802116B2 (en) 2003-02-27 2014-08-12 Novasel Australia Pty. Ltd. Poloxamer emulsion preparations
KR20040084240A (ko) * 2003-03-27 2004-10-06 (주) 코스메디 고형지질나노입자, 이를 함유하는 활성성분 전달용약학조성물 및 이의 제조방법
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WO2006102157A1 (en) * 2005-03-21 2006-09-28 Ivax Pharmaceuticals S.R.O. Crystallization inhibitor and its use in gelatin capsules
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US20090130198A1 (en) * 2007-11-21 2009-05-21 Innopharmax Inc. Pharmaceutical composition with enhanced bioavailability
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JP5567909B2 (ja) * 2010-06-17 2014-08-06 東洋カプセル株式会社 タクロリムス含有カプセル剤
WO2011162802A1 (en) 2010-06-21 2011-12-29 Virun, Inc. Compositions containing non-polar compounds
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
JO3337B1 (ar) 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
JP5717034B2 (ja) * 2012-08-27 2015-05-13 丸和バイオケミカル株式会社 マクロライド系化合物を含有する土壌線虫防除用薬剤
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Also Published As

Publication number Publication date
DE19983012T1 (de) 2001-02-01
CN1195495C (zh) 2005-04-06
TR200002586T2 (tr) 2000-11-21
EP1354582A3 (en) 2004-06-09
HK1034038A1 (en) 2001-10-12
IT1313550B1 (it) 2002-09-09
TW200422057A (en) 2004-11-01
EP1354582A2 (en) 2003-10-22
PT1059913E (pt) 2005-01-31
EP1059913B1 (en) 2004-09-29
GB2350791A (en) 2000-12-13
HK1033277A1 (en) 2001-08-24
FR2853546A1 (fr) 2004-10-15
JP2002505271A (ja) 2002-02-19
HUP0101080A3 (en) 2001-12-28
NZ506644A (en) 2004-02-27
BE1012400A5 (fr) 2000-10-03
CO4930289A1 (es) 2000-06-27
AU749217B2 (en) 2002-06-20
SK13192000A3 (sk) 2001-02-12
GB0021495D0 (en) 2000-10-18
KR20010041657A (ko) 2001-05-25
MY129274A (en) 2007-03-30
HUP0101080A2 (hu) 2001-08-28
EP1059913A1 (en) 2000-12-20
FR2800277B1 (fr) 2004-06-25
TWI236912B (en) 2005-08-01
AR015729A1 (es) 2001-05-16
TWI248368B (en) 2006-02-01
BE1013648A5 (fr) 2002-05-07
NO331800B1 (no) 2012-04-02
CZ301967B6 (cs) 2010-08-18
FR2853546B1 (fr) 2006-04-07
DE69920668T2 (de) 2005-10-06
SK285139B6 (sk) 2006-07-07
CA2322845C (en) 2009-12-08
ES2228014T3 (es) 2005-04-01
FR2800277A1 (fr) 2001-05-04
TWI257870B (en) 2006-07-11
IL138248A (en) 2006-06-11
FR2775596B1 (fr) 2004-12-24
FR2881956A1 (fr) 2006-08-18
FR2775596A1 (fr) 1999-09-10
PE20000324A1 (es) 2000-04-13
IL138248A0 (en) 2001-10-31
CN1292684A (zh) 2001-04-25
NO20004299D0 (no) 2000-08-29
CZ20003222A3 (cs) 2000-12-13
ID25908A (id) 2000-11-09
JP2004189753A (ja) 2004-07-08
AU2836199A (en) 1999-09-20
GB2350791B (en) 2003-04-02
ITMI990452A1 (it) 2000-09-05
DE69920668D1 (de) 2004-11-04
NO20004299L (no) 2000-08-29
BR9908597A (pt) 2000-11-14
ATE277599T1 (de) 2004-10-15
CA2322845A1 (en) 1999-09-10
WO1999044584A1 (en) 1999-09-10
BE1013423A5 (fr) 2002-01-15

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PL184711B1 (pl) Prekoncentrat mikroemulsji

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