TR200002586T2 - Siklosporin ya da bir makrolid içeren emülsiyon prekonsantratları - Google Patents

Siklosporin ya da bir makrolid içeren emülsiyon prekonsantratları

Info

Publication number
TR200002586T2
TR200002586T2 TR2000/02586T TR200002586T TR200002586T2 TR 200002586 T2 TR200002586 T2 TR 200002586T2 TR 2000/02586 T TR2000/02586 T TR 2000/02586T TR 200002586 T TR200002586 T TR 200002586T TR 200002586 T2 TR200002586 T2 TR 200002586T2
Authority
TR
Turkey
Prior art keywords
macrolide
containing cyclosporine
emulsion preconcentrates
emulsion
preconcentrates containing
Prior art date
Application number
TR2000/02586T
Other languages
English (en)
Turkish (tr)
Inventor
Ambuhl Michael
Luckel Barbara
Richter Friedrich
Haberlin Barbara
Meinzer Armin
Original Assignee
Novarstis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27269231&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200002586(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9804742.6A external-priority patent/GB9804742D0/en
Priority claimed from GBGB9805104.8A external-priority patent/GB9805104D0/en
Priority claimed from GBGB9805199.8A external-priority patent/GB9805199D0/en
Application filed by Novarstis Ag filed Critical Novarstis Ag
Publication of TR200002586T2 publication Critical patent/TR200002586T2/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Surgery (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TR2000/02586T 1998-03-06 1999-03-04 Siklosporin ya da bir makrolid içeren emülsiyon prekonsantratları TR200002586T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9804742.6A GB9804742D0 (en) 1998-03-06 1998-03-06 Organic compounds
GBGB9805104.8A GB9805104D0 (en) 1998-03-10 1998-03-10 Organic compounds
GBGB9805199.8A GB9805199D0 (en) 1998-03-11 1998-03-11 Organic compounds

Publications (1)

Publication Number Publication Date
TR200002586T2 true TR200002586T2 (tr) 2000-11-21

Family

ID=27269231

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02586T TR200002586T2 (tr) 1998-03-06 1999-03-04 Siklosporin ya da bir makrolid içeren emülsiyon prekonsantratları

Country Status (29)

Country Link
EP (2) EP1059913B1 (enExample)
JP (2) JP2002505271A (enExample)
KR (1) KR100443306B1 (enExample)
CN (1) CN1195495C (enExample)
AR (1) AR015729A1 (enExample)
AT (1) ATE277599T1 (enExample)
AU (1) AU749217B2 (enExample)
BE (3) BE1012400A5 (enExample)
BR (1) BR9908597A (enExample)
CA (1) CA2322845C (enExample)
CO (1) CO4930289A1 (enExample)
CZ (1) CZ301967B6 (enExample)
DE (2) DE19983012T1 (enExample)
ES (1) ES2228014T3 (enExample)
FR (4) FR2775596B1 (enExample)
GB (1) GB2350791B (enExample)
HU (1) HUP0101080A3 (enExample)
ID (1) ID25908A (enExample)
IL (2) IL138248A0 (enExample)
IT (1) IT1313550B1 (enExample)
MY (1) MY129274A (enExample)
NO (1) NO331800B1 (enExample)
NZ (1) NZ506644A (enExample)
PE (1) PE20000324A1 (enExample)
PT (1) PT1059913E (enExample)
SK (1) SK285139B6 (enExample)
TR (1) TR200002586T2 (enExample)
TW (3) TWI257870B (enExample)
WO (1) WO1999044584A1 (enExample)

Families Citing this family (45)

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IL143604A0 (en) * 1998-12-30 2002-04-21 Dexcel Ltd Dispersable concentrate for the delivery of cyclosporin
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
AU2127400A (en) * 1999-11-02 2001-05-14 Cipla Limited A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and process for preparation thereof
GB2362573A (en) * 2000-05-25 2001-11-28 Cipla Ltd Cyclosporin formulation
WO2001032142A1 (en) * 1999-11-02 2001-05-10 Cipla Limited Cyclosporin formulation
GB0008785D0 (en) * 2000-04-10 2000-05-31 Novartis Ag Organic compounds
DE10024451A1 (de) * 2000-05-18 2001-11-29 Asta Medica Ag Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
WO2003002095A1 (fr) * 2001-06-28 2003-01-09 Chugai Seiyaku Kabushiki Kaisha Preparation d'une micro-emulsion de type huile-eau
US6960563B2 (en) 2001-08-31 2005-11-01 Morton Grove Pharmaceuticals, Inc. Spontaneous emulsions containing cyclosporine
GB2391471B (en) * 2002-08-02 2005-05-04 Satishchandra Punambhai Patel Pharmaceutical compositions
KR20040047056A (ko) * 2002-11-29 2004-06-05 한미약품 주식회사 비페닐디메틸디카복실레이트의 경구용 마이크로에멀젼조성물
US8802116B2 (en) 2003-02-27 2014-08-12 Novasel Australia Pty. Ltd. Poloxamer emulsion preparations
KR20040084240A (ko) * 2003-03-27 2004-10-06 (주) 코스메디 고형지질나노입자, 이를 함유하는 활성성분 전달용약학조성물 및 이의 제조방법
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
WO2006050123A1 (en) * 2004-10-29 2006-05-11 Novartis Ag Spontaneously dispersible pharmaceutical compositions
MX2007011250A (es) * 2005-03-21 2007-11-14 Ivax Pharmaceuticals Sro Inhibidor de la cristalizacion y su uso en capsulas de gelatina.
CN101032620B (zh) * 2007-03-08 2010-05-19 上海凯昭医药科技有限公司 一种环孢素自乳化制剂及其制备方法
US20090130198A1 (en) * 2007-11-21 2009-05-21 Innopharmax Inc. Pharmaceutical composition with enhanced bioavailability
BRPI0909185A2 (pt) 2008-03-20 2015-08-25 Virun Inc Derivado de vitamina e e seus usos
MX2010010050A (es) 2008-03-20 2011-03-15 Virun Inc Star Emulsiones que incluyen un derivado de polietilen glicol de tocoferol.
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
JP5567909B2 (ja) * 2010-06-17 2014-08-06 東洋カプセル株式会社 タクロリムス含有カプセル剤
WO2011162802A1 (en) 2010-06-21 2011-12-29 Virun, Inc. Compositions containing non-polar compounds
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
JO3337B1 (ar) 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
JP5717034B2 (ja) * 2012-08-27 2015-05-13 丸和バイオケミカル株式会社 マクロライド系化合物を含有する土壌線虫防除用薬剤
EP2938324B1 (en) 2012-12-31 2023-11-08 JRX Biotechnology, Inc. Liquid topical pharmaceutical nano-emulsion formulations
KR101458466B1 (ko) * 2013-06-24 2014-11-07 한국화학연구원 면역억제제가 봉입된 마이셀을 함유하는 경구제
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016205423A2 (en) 2015-06-15 2016-12-22 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
EP3349717A4 (en) 2015-09-17 2019-04-17 JRX Biotechnology, Inc. APPROACHES TO IMPROVE SKIN HYDROGENATION OR HUMIDIFICATION
CA3078723A1 (en) 2016-11-28 2018-05-31 Nachiappan Chidambaram Oral testosterone undecanoate therapy
EP3824296B1 (en) 2018-07-20 2026-04-01 Lipocine Inc. Oral pharmaceutical composition comprising testosterone tridecanoate and/or testosterone dodecanoate for treating liver diseases
AU2019386859A1 (en) * 2018-11-26 2021-05-27 Hepion Pharmaceuticals, Inc. Pharmaceutical formulations of cyclosporine analogs
WO2024014959A2 (en) * 2022-07-15 2024-01-18 Seranovo Holding B.V. Micelle-generating formulations with improved hydrophobicity
WO2024014958A2 (en) * 2022-07-15 2024-01-18 Seranovo Holding B.V. Lides formulation platform
CN117797093A (zh) * 2024-02-29 2024-04-02 中国农业科学院农业环境与可持续发展研究所 一种以大环内酯类药物为活性成分的兽用口服纳米液体制剂

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US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
GB8903804D0 (en) * 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
JP2632010B2 (ja) * 1988-01-29 1997-07-16 三共株式会社 シクロスポリン製剤
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
DK0589843T3 (da) * 1992-09-25 2002-04-02 Novartis Ag Cyclosporinholdige farmaceutiske præparater
GB2278780B (en) * 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
JP3131112B2 (ja) * 1994-02-17 2001-01-31 株式会社資生堂 シクロスポリン含有乳化組成物
WO1995022343A1 (en) * 1994-02-17 1995-08-24 Shiseido Company, Ltd. Cyclosporin-containing emulsion composition
DK0786986T3 (da) * 1994-10-26 2002-04-29 Novartis Ag Anvendelse af en umættet fedtalkohol
MY129435A (en) * 1994-10-26 2007-04-30 Novartis Ag Pharmaceutical microemulsion preconcentrates
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
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KR980008239A (ko) * 1996-07-26 1998-04-30 김충환 사이클로스포린-함유 약학적 조성물
US6063762A (en) * 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
US6284268B1 (en) * 1997-12-10 2001-09-04 Cyclosporine Therapeutics Limited Pharmaceutical compositions containing an omega-3 fatty acid oil

Also Published As

Publication number Publication date
JP2002505271A (ja) 2002-02-19
SK285139B6 (sk) 2006-07-07
ES2228014T3 (es) 2005-04-01
PE20000324A1 (es) 2000-04-13
HUP0101080A2 (hu) 2001-08-28
CZ301967B6 (cs) 2010-08-18
EP1354582A3 (en) 2004-06-09
TWI257870B (en) 2006-07-11
FR2775596B1 (fr) 2004-12-24
AU2836199A (en) 1999-09-20
CA2322845C (en) 2009-12-08
IT1313550B1 (it) 2002-09-09
WO1999044584A1 (en) 1999-09-10
FR2800277A1 (fr) 2001-05-04
JP2004189753A (ja) 2004-07-08
CN1292684A (zh) 2001-04-25
FR2853546A1 (fr) 2004-10-15
EP1059913A1 (en) 2000-12-20
TWI236912B (en) 2005-08-01
GB2350791B (en) 2003-04-02
IL138248A (en) 2006-06-11
IL138248A0 (en) 2001-10-31
SK13192000A3 (sk) 2001-02-12
TW200422057A (en) 2004-11-01
MY129274A (en) 2007-03-30
BE1012400A5 (fr) 2000-10-03
CO4930289A1 (es) 2000-06-27
CZ20003222A3 (cs) 2000-12-13
KR20010041657A (ko) 2001-05-25
HUP0101080A3 (en) 2001-12-28
CA2322845A1 (en) 1999-09-10
GB0021495D0 (en) 2000-10-18
FR2881956A1 (fr) 2006-08-18
FR2800277B1 (fr) 2004-06-25
ID25908A (id) 2000-11-09
HK1033277A1 (en) 2001-08-24
NO331800B1 (no) 2012-04-02
NZ506644A (en) 2004-02-27
PT1059913E (pt) 2005-01-31
BE1013423A5 (fr) 2002-01-15
DE19983012T1 (de) 2001-02-01
EP1059913B1 (en) 2004-09-29
TWI248368B (en) 2006-02-01
GB2350791A (en) 2000-12-13
DE69920668D1 (de) 2004-11-04
ITMI990452A1 (it) 2000-09-05
FR2775596A1 (fr) 1999-09-10
AR015729A1 (es) 2001-05-16
BR9908597A (pt) 2000-11-14
DE69920668T2 (de) 2005-10-06
NO20004299L (no) 2000-08-29
KR100443306B1 (ko) 2004-08-09
EP1354582A2 (en) 2003-10-22
BE1013648A5 (fr) 2002-05-07
ATE277599T1 (de) 2004-10-15
FR2853546B1 (fr) 2006-04-07
HK1034038A1 (en) 2001-10-12
CN1195495C (zh) 2005-04-06
AU749217B2 (en) 2002-06-20
NO20004299D0 (no) 2000-08-29

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