KE3858A - An indole derivative - Google Patents

An indole derivative

Info

Publication number
KE3858A
KE3858A KE3858A KE385889A KE3858A KE 3858 A KE3858 A KE 3858A KE 3858 A KE3858 A KE 3858A KE 385889 A KE385889 A KE 385889A KE 3858 A KE3858 A KE 3858A
Authority
KE
Kenya
Prior art keywords
indole derivative
indole
derivative
Prior art date
Application number
KE3858A
Other languages
English (en)
Inventor
William Oxford Alexander
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10564759&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KE3858(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of KE3858A publication Critical patent/KE3858A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/14—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom with carbocyclic rings directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KE3858A 1984-08-01 1989-02-07 An indole derivative KE3858A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848419575A GB8419575D0 (en) 1984-08-01 1984-08-01 Chemical compounds

Publications (1)

Publication Number Publication Date
KE3858A true KE3858A (en) 1989-06-02

Family

ID=10564759

Family Applications (1)

Application Number Title Priority Date Filing Date
KE3858A KE3858A (en) 1984-08-01 1989-02-07 An indole derivative

Country Status (42)

Country Link
US (1) US5037845A (es)
JP (1) JPH0623197B2 (es)
KR (1) KR930003759B1 (es)
AT (1) AT386196B (es)
AU (1) AU573878B2 (es)
BE (1) BE903006A (es)
CA (1) CA1241004A (es)
CH (1) CH666026A5 (es)
CZ (1) CZ280530B6 (es)
DE (1) DE3527648A1 (es)
DK (1) DK158942C (es)
DO (1) DOP1989004759A (es)
EC (1) ECSP941096A (es)
EG (1) EG17283A (es)
ES (6) ES8700234A1 (es)
FI (1) FI78466C (es)
FR (1) FR2568571B1 (es)
GB (1) GB8419575D0 (es)
GR (1) GR851850B (es)
HK (1) HK33289A (es)
HU (1) HU201738B (es)
IE (1) IE58122B1 (es)
IL (1) IL75986A (es)
IS (1) IS1430B6 (es)
IT (1) IT1207325B (es)
JO (1) JO1379B1 (es)
KE (1) KE3858A (es)
LU (2) LU86032A1 (es)
MA (1) MA20499A1 (es)
MX (2) MX159672A (es)
NL (2) NL188642C (es)
NO (2) NO164653C (es)
NZ (1) NZ212948A (es)
PH (2) PH22850A (es)
PL (1) PL146005B1 (es)
PT (1) PT80900B (es)
SE (1) SE452460B (es)
SK (1) SK277952B6 (es)
SU (1) SU1498386A3 (es)
UA (1) UA6329A1 (es)
ZA (1) ZA855818B (es)
ZW (1) ZW12485A1 (es)

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US8329734B2 (en) * 2009-07-27 2012-12-11 Afgin Pharma Llc Topical therapy for migraine
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JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
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KR101517415B1 (ko) 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
US8592424B2 (en) * 2008-06-30 2013-11-26 Afgin Pharma Llc Topical regional neuro-affective therapy
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US10716766B2 (en) 2015-03-02 2020-07-21 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoids
US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
US20180049994A1 (en) 2016-08-16 2018-02-22 Afgin Pharma, Llc Topical regional neuro-affective therapy with caryophyllene

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Also Published As

Publication number Publication date
AU573878B2 (en) 1988-06-23
DE3527648C2 (es) 1993-08-26
DK158942C (da) 1991-01-21
ES557481A0 (es) 1988-02-16
PT80900B (pt) 1987-12-30
ECSP941096A (es) 1995-01-16
ZA855818B (en) 1986-04-30
NL8502171A (nl) 1986-03-03
PT80900A (en) 1985-09-01
UA6329A1 (uk) 1994-12-29
FI78466C (fi) 1989-08-10
IT1207325B (it) 1989-05-17
ZW12485A1 (en) 1986-02-26
ES8801788A1 (es) 1988-02-16
SE452460B (sv) 1987-11-30
ES557483A0 (es) 1988-02-16
US5037845A (en) 1991-08-06
SE8503680D0 (sv) 1985-08-01
AU4568985A (en) 1986-02-06
NO164653B (no) 1990-07-23
CZ280530B6 (cs) 1996-02-14
ES8700234A1 (es) 1986-10-16
JPS6147464A (ja) 1986-03-07
HU201738B (en) 1990-12-28
MA20499A1 (fr) 1986-04-01
PH24117A (en) 1990-03-05
CZ404191A3 (en) 1993-04-14
SE8503680L (sv) 1986-02-02
ATA226685A (de) 1987-12-15
CA1241004A (en) 1988-08-23
IS3034A7 (is) 1986-02-02
CH666026A5 (fr) 1988-06-30
FI852969A0 (fi) 1985-08-01
IE851918L (en) 1986-02-01
ES552047A0 (es) 1987-12-16
KR860001788A (ko) 1986-03-22
IT8548435A0 (it) 1985-08-01
HUT40077A (en) 1986-11-28
GR851850B (es) 1985-11-26
LU86032A1 (fr) 1986-02-18
PH22850A (en) 1989-01-19
ES545810A0 (es) 1986-10-16
FR2568571B1 (fr) 1988-09-23
SK404191A3 (en) 1995-09-13
HK33289A (en) 1989-04-28
DE3527648A1 (de) 1986-02-13
SK277952B6 (en) 1995-09-13
PL254800A1 (en) 1986-10-21
ES8801204A1 (es) 1987-12-16
NL930065I2 (nl) 1993-10-01
SU1498386A3 (ru) 1989-07-30
IE58122B1 (en) 1993-07-14
NO164653C (no) 1990-11-07
NL930065I1 (nl) 1993-09-01
ES557480A0 (es) 1988-02-16
FI78466B (fi) 1989-04-28
MX14221A (es) 1993-10-01
IL75986A0 (en) 1985-12-31
ES557482A0 (es) 1988-03-01
BE903006A (fr) 1986-02-03
PL146005B1 (en) 1988-12-31
MX159672A (es) 1989-08-02
LU88266I2 (es) 1994-02-03
DOP1989004759A (es) 1999-02-06
ES8801789A1 (es) 1988-02-16
ES8801900A1 (es) 1988-03-01
DK158942B (da) 1990-08-06
EG17283A (en) 1992-06-30
FR2568571A1 (fr) 1986-02-07
DK351185D0 (da) 1985-08-01
AT386196B (de) 1988-07-11
JO1379B1 (en) 1986-11-30
NZ212948A (en) 1989-05-29
IS1430B6 (is) 1990-07-16
KR930003759B1 (ko) 1993-05-10
NO853046L (no) 1986-02-03
NL188642C (nl) 1992-08-17
NO1994023I1 (no) 1994-11-09
ES8801790A1 (es) 1988-02-16
IL75986A (en) 1989-02-28
FI852969L (fi) 1986-02-02
JPH0623197B2 (ja) 1994-03-30
DK351185A (da) 1986-02-02
GB8419575D0 (en) 1984-09-05

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