JPWO2020232256A5 - - Google Patents
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- JPWO2020232256A5 JPWO2020232256A5 JP2021567815A JP2021567815A JPWO2020232256A5 JP WO2020232256 A5 JPWO2020232256 A5 JP WO2020232256A5 JP 2021567815 A JP2021567815 A JP 2021567815A JP 2021567815 A JP2021567815 A JP 2021567815A JP WO2020232256 A5 JPWO2020232256 A5 JP WO2020232256A5
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- cancer
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- pharmaceutically acceptable
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- 229910052799 carbon Inorganic materials 0.000 claims description 30
- 125000004043 oxo group Chemical group O=* 0.000 claims description 24
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 claims description 18
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims description 18
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims description 18
- 125000000623 heterocyclic group Chemical group 0.000 claims description 16
- 125000001424 substituent group Chemical group 0.000 claims description 15
- 125000003545 alkoxy group Chemical group 0.000 claims description 14
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- 229910052736 halogen Inorganic materials 0.000 claims description 12
- 150000002367 halogens Chemical class 0.000 claims description 12
- 125000003003 spiro group Chemical group 0.000 claims description 12
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- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims description 10
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962848114P | 2019-05-15 | 2019-05-15 | |
| US62/848,114 | 2019-05-15 | ||
| PCT/US2020/032904 WO2020232256A1 (en) | 2019-05-15 | 2020-05-14 | Triaryl compounds for treatment of pd-l1 diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022531970A JP2022531970A (ja) | 2022-07-12 |
| JPWO2020232256A5 true JPWO2020232256A5 (enExample) | 2023-05-19 |
| JP7656547B2 JP7656547B2 (ja) | 2025-04-03 |
Family
ID=73289294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021567815A Active JP7656547B2 (ja) | 2019-05-15 | 2020-05-14 | Ｐｄ－ｌ１疾患治療用のトリアリール化合物 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11266643B2 (enExample) |
| EP (1) | EP3968996A4 (enExample) |
| JP (1) | JP7656547B2 (enExample) |
| KR (1) | KR20220009420A (enExample) |
| CN (1) | CN114340633A (enExample) |
| AU (2) | AU2020276277B2 (enExample) |
| BR (1) | BR112021022659A2 (enExample) |
| CA (1) | CA3139526A1 (enExample) |
| IL (1) | IL287843B2 (enExample) |
| MA (1) | MA55974A (enExample) |
| MX (1) | MX2021013819A (enExample) |
| SG (1) | SG11202112310TA (enExample) |
| WO (1) | WO2020232256A1 (enExample) |
| ZA (1) | ZA202108626B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102401963B1 (ko) | 2016-06-27 | 2022-05-25 | 케모센트릭스, 인크. | 면역조절제 화합물 |
| US10919852B2 (en) | 2017-07-28 | 2021-02-16 | Chemocentryx, Inc. | Immunomodulator compounds |
| KR102670486B1 (ko) | 2017-08-08 | 2024-05-28 | 케모센트릭스, 인크. | 마크로사이클릭 면역조절제 |
| EP3755311A4 (en) | 2018-02-22 | 2021-11-10 | ChemoCentryx, Inc. | INDANAMINE AS PD-L1 ANTAGONISTS |
| MA55974A (fr) * | 2019-05-15 | 2022-03-23 | Chemocentryx Inc | Composés triaryles pour le traitement de maladies pd-l1 |
| SG11202112875UA (en) * | 2019-06-20 | 2021-12-30 | Chemocentryx Inc | Compounds for treatment of pd-l1 diseases |
| CN114206338B (zh) | 2019-07-10 | 2025-12-12 | 凯莫森特里克斯股份有限公司 | 作为pd-l1抑制剂的二氢化茚类 |
| PE20221445A1 (es) * | 2019-10-16 | 2022-09-21 | Chemocentryx Inc | Heteroaril bifenil amidas para el tratamiento de enfermedades relacionadas con el ligando pd-l1 |
| CR20220216A (es) | 2019-10-16 | 2023-01-09 | Chemocentryx Inc | Aminas de heteroaril-bifenilo para el tratamiento de enfermedades pd-l1 |
| WO2021093817A1 (zh) * | 2019-11-15 | 2021-05-20 | 杭州和正医药有限公司 | 免疫调节化合物、组合物及其应用 |
| KR20220125278A (ko) * | 2020-01-03 | 2022-09-14 | 상하이 한서 바이오메디컬 컴퍼니 리미티드 | 비페닐 유도체 억제제, 이의 제조 방법 및 용도 |
| TW202216694A (zh) * | 2020-06-23 | 2022-05-01 | 美商卡默森屈有限公司 | 使用雜芳基-聯苯醯胺衍生物治療癌症之方法 |
| WO2022152316A1 (zh) * | 2021-01-18 | 2022-07-21 | 南京明德新药研发有限公司 | 联苯衍生物及其应用 |
| BR112023026747A2 (pt) | 2021-06-18 | 2024-03-12 | Aligos Therapeutics Inc | Métodos e composições para direcionamento de pd-l1 |
| MX2024007042A (es) | 2021-12-09 | 2024-09-04 | Deciphera Pharmaceuticals Llc | Inhibidores de raf quinasa y metodos de uso de los mismos. |
| US12428427B2 (en) | 2021-12-16 | 2025-09-30 | Aligos Therapeutics, Inc. | Methods and compositions for targeting PD-L1 |
| CN115010658B (zh) * | 2022-05-11 | 2023-06-27 | 南方医科大学 | 一种化合物及其制备方法与应用 |
| WO2024018403A1 (en) * | 2022-07-21 | 2024-01-25 | Arbutus Biopharma Corporation | Substituted imidazoamide compounds, and methods using same |
| WO2024134466A1 (en) * | 2022-12-21 | 2024-06-27 | Arbutus Biopharma Corporation | Substituted arylamine compounds, substituted heteroarylamine compounds, and methods using same |
| US20240277706A1 (en) * | 2023-01-20 | 2024-08-22 | Aligos Therapeutics, Inc. | Methods and compostitions for targeting pd-l1 |
| WO2025015063A1 (en) * | 2023-07-13 | 2025-01-16 | Aligos Therapeutics, Inc. | Methods and compositions for targeting pd-l1 |
| CN116903489B (zh) * | 2023-07-14 | 2025-09-02 | 北京汉典制药有限公司 | 三联苯类化合物、其制备方法及其应用 |
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| GB9604926D0 (en) * | 1996-03-08 | 1996-05-08 | Sandoz Ltd | Organic compounds |
| EP2402318A1 (en) | 2006-03-31 | 2012-01-04 | Novartis AG | DGAT inhibitors |
| DK1847524T3 (da) * | 2006-04-21 | 2010-01-11 | Cellzome Ltd | Terphenylderivater til behandling af Alzheimers sygdom |
| WO2008008059A1 (en) | 2006-07-12 | 2008-01-17 | Locus Pharmaceuticals, Inc. | Anti-cancer agents ans uses thereof |
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- 2020-05-14 BR BR112021022659A patent/BR112021022659A2/pt unknown
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- 2020-05-14 KR KR1020217040832A patent/KR20220009420A/ko active Pending
- 2020-05-14 CN CN202080051848.0A patent/CN114340633A/zh active Pending
- 2020-05-14 US US16/874,212 patent/US11266643B2/en active Active
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