KR20220009420A - Pd-l1 질환의 치료를 위한 트리아릴 화합물 - Google Patents

Pd-l1 질환의 치료를 위한 트리아릴 화합물 Download PDF

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KR20220009420A
KR20220009420A KR1020217040832A KR20217040832A KR20220009420A KR 20220009420 A KR20220009420 A KR 20220009420A KR 1020217040832 A KR1020217040832 A KR 1020217040832A KR 20217040832 A KR20217040832 A KR 20217040832A KR 20220009420 A KR20220009420 A KR 20220009420A
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methyl
dimethyl
methoxy
compound
terphenyl
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Korean (ko)
Inventor
핑첸 판
크리스토퍼 랑게
벤카트 레디 말리
달렌 제이. 맥머트리
비엥캄 말라통
스리니바스 푼나
라진더 싱
주 양
이빈 젱
펭라이 장
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케모센트릭스, 인크.
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Publication of KR20220009420A publication Critical patent/KR20220009420A/ko
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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