AU2020276277B2 - Triaryl compounds for treatment of PD-L1 diseases - Google Patents

Triaryl compounds for treatment of PD-L1 diseases Download PDF

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AU2020276277B2
AU2020276277B2 AU2020276277A AU2020276277A AU2020276277B2 AU 2020276277 B2 AU2020276277 B2 AU 2020276277B2 AU 2020276277 A AU2020276277 A AU 2020276277A AU 2020276277 A AU2020276277 A AU 2020276277A AU 2020276277 B2 AU2020276277 B2 AU 2020276277B2
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methyl
dimethyl
group
compound
methoxy
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AU2020276277A1 (en
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Pingchen Fan
Christopher Lange
Viengkham Malathong
Venkat Reddy Mali
Darren J. Mcmurtrie
Sreenivas Punna
Rajinder Singh
Ju Yang
Yibin Zeng
Penglie Zhang
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Chemocentryx Inc
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Chemocentryx Inc
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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