JPWO2020257549A5 - - Google Patents
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- JPWO2020257549A5 JPWO2020257549A5 JP2021574927A JP2021574927A JPWO2020257549A5 JP WO2020257549 A5 JPWO2020257549 A5 JP WO2020257549A5 JP 2021574927 A JP2021574927 A JP 2021574927A JP 2021574927 A JP2021574927 A JP 2021574927A JP WO2020257549 A5 JPWO2020257549 A5 JP WO2020257549A5
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- cancer
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- agents
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- pharmaceutically acceptable
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- 150000001875 compounds Chemical class 0.000 claims 21
- 150000003839 salts Chemical class 0.000 claims 21
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- 229910018828 PO3H2 Inorganic materials 0.000 claims 9
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 8
- 229910052739 hydrogen Inorganic materials 0.000 claims 8
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 claims 7
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 7
- 229910006074 SO2NH2 Inorganic materials 0.000 claims 7
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- 229910052731 fluorine Inorganic materials 0.000 claims 5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025123800A JP2025170244A (ja) | 2019-06-20 | 2025-07-24 | Pd-l1疾患の治療のための化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962864002P | 2019-06-20 | 2019-06-20 | |
| US62/864,002 | 2019-06-20 | ||
| PCT/US2020/038586 WO2020257549A2 (en) | 2019-06-20 | 2020-06-19 | Compounds for treatment of pd-l1 diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025123800A Division JP2025170244A (ja) | 2019-06-20 | 2025-07-24 | Pd-l1疾患の治療のための化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022536845A JP2022536845A (ja) | 2022-08-19 |
| JPWO2020257549A5 true JPWO2020257549A5 (enExample) | 2023-06-14 |
Family
ID=74040685
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021574927A Pending JP2022536845A (ja) | 2019-06-20 | 2020-06-19 | Pd-l1疾患の治療のための化合物 |
| JP2025123800A Pending JP2025170244A (ja) | 2019-06-20 | 2025-07-24 | Pd-l1疾患の治療のための化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025123800A Pending JP2025170244A (ja) | 2019-06-20 | 2025-07-24 | Pd-l1疾患の治療のための化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11485708B2 (enExample) |
| EP (1) | EP3986392A4 (enExample) |
| JP (2) | JP2022536845A (enExample) |
| KR (1) | KR102841588B1 (enExample) |
| CN (1) | CN114072135A (enExample) |
| AU (1) | AU2020294781B2 (enExample) |
| BR (1) | BR112021023750A2 (enExample) |
| CA (1) | CA3139242A1 (enExample) |
| IL (1) | IL288523A (enExample) |
| MA (1) | MA55325A (enExample) |
| MX (1) | MX2021015708A (enExample) |
| SG (1) | SG11202112875UA (enExample) |
| WO (1) | WO2020257549A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100272695A1 (en) | 2009-04-22 | 2010-10-28 | Alan Agulnick | Cell compositions derived from dedifferentiated reprogrammed cells |
| US8859286B2 (en) | 2013-03-14 | 2014-10-14 | Viacyte, Inc. | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells |
| EP3755311A4 (en) | 2018-02-22 | 2021-11-10 | ChemoCentryx, Inc. | INDANAMINE AS PD-L1 ANTAGONISTS |
| MA55974A (fr) | 2019-05-15 | 2022-03-23 | Chemocentryx Inc | Composés triaryles pour le traitement de maladies pd-l1 |
| CN114206338B (zh) | 2019-07-10 | 2025-12-12 | 凯莫森特里克斯股份有限公司 | 作为pd-l1抑制剂的二氢化茚类 |
| PE20221445A1 (es) | 2019-10-16 | 2022-09-21 | Chemocentryx Inc | Heteroaril bifenil amidas para el tratamiento de enfermedades relacionadas con el ligando pd-l1 |
| CR20220216A (es) | 2019-10-16 | 2023-01-09 | Chemocentryx Inc | Aminas de heteroaril-bifenilo para el tratamiento de enfermedades pd-l1 |
| JP2023527315A (ja) | 2020-05-22 | 2023-06-28 | アリゴス セラピューティクス インコーポレイテッド | Pd-l1を標的とするための方法及び組成物 |
| EP4274559A4 (en) * | 2021-01-05 | 2024-12-11 | Southern Research Institute | PROGRAMMED DEATH-LIGAND-1 MODULATORS |
| TWI770866B (zh) * | 2021-03-10 | 2022-07-11 | 國立清華大學 | 鹵化物材料及包含該鹵化物材料之光學單元和光電元件 |
| IL309620A (en) * | 2021-07-02 | 2024-02-01 | Ascletis Bioscience Co Ltd | Heterocyclic compounds as immunomodulators of PD-L1 interactions |
| US12428427B2 (en) | 2021-12-16 | 2025-09-30 | Aligos Therapeutics, Inc. | Methods and compositions for targeting PD-L1 |
| CN115010658B (zh) * | 2022-05-11 | 2023-06-27 | 南方医科大学 | 一种化合物及其制备方法与应用 |
| WO2024088036A1 (zh) * | 2022-10-26 | 2024-05-02 | 西安新通药物研究股份有限公司 | 一种非对称性联苯衍生物及其制备方法与医药用途 |
| CN119768390A (zh) * | 2022-11-22 | 2025-04-04 | 西安新通药物研究股份有限公司 | 新型双环类pd-l1抑制剂及其制备方法与医药用途 |
| CN116903489B (zh) * | 2023-07-14 | 2025-09-02 | 北京汉典制药有限公司 | 三联苯类化合物、其制备方法及其应用 |
| KR102841053B1 (ko) * | 2023-08-01 | 2025-08-04 | (주)아이랩 | Pd-l1 억제제로서 신규한 바이페닐 유도체 |
Family Cites Families (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2402318A1 (en) | 2006-03-31 | 2012-01-04 | Novartis AG | DGAT inhibitors |
| WO2008008059A1 (en) | 2006-07-12 | 2008-01-17 | Locus Pharmaceuticals, Inc. | Anti-cancer agents ans uses thereof |
| WO2015034820A1 (en) | 2013-09-04 | 2015-03-12 | Bristol-Myers Squibb Company | Compounds useful as immunomodulators |
| SG11201601679TA (en) | 2013-09-06 | 2016-04-28 | Aurigene Discovery Tech Ltd | 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators |
| ES2675027T3 (es) | 2013-09-06 | 2018-07-05 | Aurigene Discovery Technologies Limited | Derivados de 1,2,4-oxadiazol como inmunomoduladores |
| US9850225B2 (en) | 2014-04-14 | 2017-12-26 | Bristol-Myers Squibb Company | Compounds useful as immunomodulators |
| JP6767096B2 (ja) * | 2014-12-11 | 2020-10-14 | リティックス バイオファーマ エイエス | 免疫チェックポイント阻害剤の組み合わせ |
| US10745382B2 (en) | 2015-10-15 | 2020-08-18 | Bristol-Myers Squibb Company | Compounds useful as immunomodulators |
| MA52119A (fr) | 2015-10-19 | 2018-08-29 | Ncyte Corp | Composés hétérocycliques utilisés comme immunomodulateurs |
| MY199220A (en) | 2015-11-19 | 2023-10-20 | Incyte Corp | Heterocyclic compounds as immunomodulators |
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