|
US5080898A
(en)
|
1982-05-12 |
1992-01-14 |
The University Hospital |
Enzymatically active toxin coupled to a cell-specific ligand
|
|
US6022950A
(en)
|
1984-06-07 |
2000-02-08 |
Seragen, Inc. |
Hybrid molecules having translocation region and cell-binding region
|
|
US5668255A
(en)
|
1984-06-07 |
1997-09-16 |
Seragen, Inc. |
Hybrid molecules having translocation region and cell-binding region
|
|
US5091178A
(en)
|
1986-02-21 |
1992-02-25 |
Oncogen |
Tumor therapy with biologically active anti-tumor antibodies
|
|
US7838216B1
(en)
|
1986-03-05 |
2010-11-23 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Human gene related to but distinct from EGF receptor gene
|
|
WO1989006692A1
(en)
|
1988-01-12 |
1989-07-27 |
Genentech, Inc. |
Method of treating tumor cells by inhibiting growth factor receptor function
|
|
US5135736A
(en)
|
1988-08-15 |
1992-08-04 |
Neorx Corporation |
Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
|
|
DE69031120T2
(de)
|
1989-05-19 |
1998-01-15 |
Genentech, Inc., South San Francisco, Calif. |
Her2 extrazellulare domäne
|
|
WO1991009871A1
(en)
|
1989-12-22 |
1991-07-11 |
Seragen Incorporated |
Hybrid molecules having translocation region and cell-binding region
|
|
US5578482A
(en)
|
1990-05-25 |
1996-11-26 |
Georgetown University |
Ligand growth factors that bind to the erbB-2 receptor protein and induce cellular responses
|
|
US5635384A
(en)
|
1990-06-11 |
1997-06-03 |
Dowelanco |
Ribosome-inactivating proteins, inactive precursor forms thereof, a process for making and a method of using
|
|
US5834229A
(en)
|
1991-05-24 |
1998-11-10 |
Genentech, Inc. |
Nucleic acids vectors and host cells encoding and expressing heregulin 2-α
|
|
IL101943A0
(en)
|
1991-05-24 |
1992-12-30 |
Genentech Inc |
Structure,production and use of heregulin
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
WO1994026910A1
(en)
|
1993-05-12 |
1994-11-24 |
Xoma Corporation |
Immunotoxins comprising gelonin and an antibody
|
|
US5621083A
(en)
|
1991-11-04 |
1997-04-15 |
Xoma Corporation |
Immunotoxins comprising ribosome-inactivating proteins
|
|
US6146850A
(en)
|
1991-11-04 |
2000-11-14 |
Xoma Corporation |
Proteins encoding gelonin sequences
|
|
WO1993021319A1
(en)
|
1992-04-08 |
1993-10-28 |
Cetus Oncology Corporation |
HUMANIZED C-erbB-2 SPECIFIC ANTIBODIES
|
|
EP0655924A4
(en)
|
1992-06-30 |
1996-09-11 |
Oncologix Inc |
A COMBINATION OF MONOCLONAL ANTIBODIES AGAINST erbB-2 AND METHOD FOR THEIR USE.
|
|
FR2697695B1
(fr)
|
1992-11-04 |
1995-01-13 |
Cachan Ecole Normale Superieur |
Dispositif de conversion électromécanique produisant un mouvement en particulier linéaire.
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
AU5431196A
(en)
|
1995-03-24 |
1996-10-16 |
Ophidian Pharmaceuticals |
Treatment for verotoxin-producing escherichia coli
|
|
US5667786A
(en)
|
1995-06-07 |
1997-09-16 |
Novavax, Inc. |
Method for treating tumors with a toxin
|
|
CA2245835A1
(en)
|
1995-06-14 |
1997-01-03 |
The Regents Of The University Of California |
Novel high affinity human antibodies to tumor antigens
|
|
US5783186A
(en)
|
1995-12-05 |
1998-07-21 |
Amgen Inc. |
Antibody-induced apoptosis
|
|
US5858682A
(en)
|
1996-08-02 |
1999-01-12 |
Pharmingen |
E2A/pbx1 fusion protein specific monoclonal antibodies
|
|
EP0921167A4
(en)
|
1996-08-22 |
2000-01-12 |
Kaneka Corp |
CURABLE COMPOSITION FOR EXTERIOR COATING AND ARTICLES THEREOF COVERED
|
|
CZ295838B6
(cs)
|
1996-09-09 |
2005-11-16 |
Zealand Pharma A/S |
Způsob výroby peptidů
|
|
WO1998011229A2
(en)
|
1996-09-10 |
1998-03-19 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Histidine-tagged shiga toxins, toxoids, and protein fusions with such toxins and toxoids, methods for the purification and preparation thereof
|
|
US5770380A
(en)
|
1996-09-13 |
1998-06-23 |
University Of Pittsburgh |
Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
FR2766193B1
(fr)
|
1997-07-18 |
2001-09-14 |
Inst Curie |
Polypeptide chimerique comprenant le fragment b de la toxine shiga et des peptides d'interet therapeutique
|
|
CA2222993A1
(en)
|
1998-02-04 |
1999-08-04 |
The Ontario Cancer Institute |
A method for using a ribosome-inactivating protein complex as a structural template and a molecular search engine in the design, construction and screening of combinatorial protein libraries
|
|
WO1999062526A2
(en)
|
1998-06-05 |
1999-12-09 |
Mayo Foundation For Medical Education And Research |
Use of genetically engineered antibodies to cd38 to treat multiple myeloma
|
|
US7157418B1
(en)
|
1998-07-22 |
2007-01-02 |
Osprey Pharmaceuticals, Ltd. |
Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders
|
|
ES2205849T3
(es)
|
1998-07-22 |
2004-05-01 |
Osprey Pharmaceuticals Limited |
Conjugados para tratar alteraciones inflamatorias y asociadas con daños tisulares.
|
|
US6770456B1
(en)
|
1998-07-29 |
2004-08-03 |
Ludwig Institute For Cancer Research |
Endogenous retrovirus tumor associated nucleic acids and antigens
|
|
WO2000020579A1
(en)
|
1998-10-02 |
2000-04-13 |
Mcmaster University |
Spliced form of erbb-2/neu oncogene
|
|
US7625859B1
(en)
|
2000-02-16 |
2009-12-01 |
Oregon Health & Science University |
HER-2 binding antagonists
|
|
US7527787B2
(en)
|
2005-10-19 |
2009-05-05 |
Ibc Pharmaceuticals, Inc. |
Multivalent immunoglobulin-based bioactive assemblies
|
|
US7144991B2
(en)
|
1999-06-07 |
2006-12-05 |
Aletheon Pharmaceuticals, Inc. |
Streptavidin expressed gene fusions and methods of use thereof
|
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
WO2001001748A2
(en)
|
1999-07-02 |
2001-01-11 |
Genentech, Inc. |
Peptide compounds that bind her2
|
|
US6492498B1
(en)
|
1999-11-15 |
2002-12-10 |
Regents Of The University Of Minnesota |
Multimeric immunotoxins
|
|
US7267973B2
(en)
|
2000-03-22 |
2007-09-11 |
Sibtech, Inc. |
Nucleic acids encoding recombinant proteins containing Shiga-like toxin and vascular endothelial growth factor
|
|
US20010031485A1
(en)
|
2000-03-22 |
2001-10-18 |
Sibtech, Inc. |
Recombinant proteins containing Shiga-like toxin and vascular endothelial growth factor fragments
|
|
CN101289511A
(zh)
|
2000-04-11 |
2008-10-22 |
杰南技术公司 |
多价抗体及其应用
|
|
US7306801B2
(en)
|
2000-05-15 |
2007-12-11 |
Health Research, Inc. |
Methods of therapy for cancers characterized by overexpression of the HER2 receptor protein
|
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
|
WO2003055439A2
(en)
|
2001-07-18 |
2003-07-10 |
The Regents Of The University Of California |
Her2/neu target antigen and use of same to stimulate an immune response
|
|
WO2003066854A1
(fr)
|
2002-02-04 |
2003-08-14 |
Yoshida, Hideo |
Agent anticancereux utilisant des variantes de verotoxines
|
|
US20040248151A1
(en)
|
2002-04-05 |
2004-12-09 |
Ventana Medical Systems, Inc. |
Method for predicting the response to HER2-directed therapy
|
|
US7435797B2
(en)
|
2002-04-10 |
2008-10-14 |
Genentech, Inc. |
Anti-HER2 antibody variants
|
|
US7449480B2
(en)
|
2002-05-14 |
2008-11-11 |
Baylor College Of Medicine |
Small molecule inhibitors of HER2 expression
|
|
US7019017B2
(en)
|
2002-05-14 |
2006-03-28 |
Baylor College Of Medicine |
Small molecule inhibitors of HER2 expression
|
|
EP3263596A1
(en)
|
2002-12-16 |
2018-01-03 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
|
US7875586B2
(en)
|
2002-12-20 |
2011-01-25 |
The Johns Hopkins University |
Treatment of metastatic colon cancer with b-subunit of shiga toxin
|
|
AU2003294023B2
(en)
|
2003-01-03 |
2008-01-31 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Rhesus HER2/neu, nucleotides encoding same, and uses thereof
|
|
WO2005000902A1
(en)
|
2003-06-30 |
2005-01-06 |
Mu-Hyeon Choe |
The dimer of chimeric recombinant binding domain-functional group fusion formed via disulfide-bond-bridge and the processes for producing the same
|
|
US7993650B2
(en)
|
2003-07-04 |
2011-08-09 |
Affibody Ab |
Polypeptides having binding affinity for HER2
|
|
JP2007517763A
(ja)
|
2003-08-01 |
2007-07-05 |
エイアンドジー ファーマスーティカル インコーポレイテッド |
Her2アンタゴニストを用いた治療への感受性を回復させる組成物および方法
|
|
US8147832B2
(en)
|
2003-08-14 |
2012-04-03 |
Merck Patent Gmbh |
CD20-binding polypeptide compositions and methods
|
|
US7982011B2
(en)
|
2003-11-25 |
2011-07-19 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Mutated anti-cd22 antibodies and immunoconjugates
|
|
EP1687016A4
(en)
|
2003-11-25 |
2009-07-29 |
Anjin Corp |
GENETIC VARIANT OF DIPHTHERIC TOXIN
|
|
US20070298434A1
(en)
|
2004-03-26 |
2007-12-27 |
Jean Gariepy |
Library of Toxin Mutants, and Methods of Using Same
|
|
KR20140032004A
(ko)
|
2004-07-22 |
2014-03-13 |
제넨테크, 인크. |
Her2 항체 조성물
|
|
EP2567976B1
(en)
|
2005-03-23 |
2017-07-19 |
Genmab A/S |
Antibodies against CD38 for treatment of multiple myeloma
|
|
US7771955B2
(en)
|
2005-06-09 |
2010-08-10 |
University Of Maryland |
Affinity membrane for capture of a target biomolecule and formation thereof by site-directed immobilization of a capture biomolecule
|
|
CN104356236B
(zh)
|
2005-07-01 |
2020-07-03 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
|
FI20055417A0
(fi)
|
2005-07-20 |
2005-07-20 |
Glykos Finland Oy |
Syöpäpesifiset glykaanit ja niiden käyttö
|
|
JP2009502936A
(ja)
|
2005-07-25 |
2009-01-29 |
トルビオン ファーマシューティカルズ, インコーポレイテッド |
Cd20特異的結合分子の単一投与量
|
|
ES2493465T3
(es)
|
2005-09-26 |
2014-09-11 |
Molecular Templates, Inc. |
Biblioteca a partir de toxinas mutantes y procesos de utilización de la misma
|
|
JP2009520468A
(ja)
|
2005-12-23 |
2009-05-28 |
ヴィヴェンティア バイオテック インコーポレーティッド |
融合タンパク質ライブラリーの作製法およびスクリーニング法、ならびにそれらの使用
|
|
JP5409014B2
(ja)
|
2006-02-16 |
2014-02-05 |
ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド |
志賀トキソイドキメラタンパク質
|
|
BRPI0720647A2
(pt)
|
2006-12-29 |
2014-01-14 |
Osprey Pharmaceuticals Usa Inc |
Processos de seleção e produção de toxinas modificadas, conjugados contendo toxinas modificadas e usos dos mesmos
|
|
ES2798758T3
(es)
|
2007-06-06 |
2020-12-14 |
Sarepta Therapeutics Inc |
Proteínas variantes de empalme her2 y her3 solubles, oligonucleótidos de cambio de empalme y su uso en el tratamiento de enfermedades
|
|
JP2010530895A
(ja)
|
2007-06-21 |
2010-09-16 |
アンジェリカ セラピューティックス,インク. |
修飾毒素
|
|
US7887801B2
(en)
|
2007-07-13 |
2011-02-15 |
Topotarget Germany Ag |
Optimized DNA and protein sequence of an antibody to improve quality and yield of bacterially expressed antibody fusion proteins
|
|
WO2009017823A2
(en)
|
2007-08-01 |
2009-02-05 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health Of Human Services, National Institutes Of Health |
A fold-back diabody diphtheria toxin immunotoxin and methods of use
|
|
PL2197903T3
(pl)
|
2007-09-04 |
2015-03-31 |
Us Gov Health & Human Services |
Delecje w domenie ii egzotoksyny a psuedomonas zmniejszające toksyczność niespecyficzną
|
|
WO2009088403A2
(en)
|
2007-10-08 |
2009-07-16 |
Rutgers, The State University |
Nontoxic shiga-like toxin mutant compositions and methods
|
|
CA2705289A1
(en)
|
2007-11-13 |
2009-05-22 |
The Scripps Research Institute |
Production of cytotoxic antibody-toxin fusion in eukaryotic algae
|
|
EP2220120A2
(en)
|
2007-11-27 |
2010-08-25 |
Ablynx N.V. |
Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
|
|
JP5337815B2
(ja)
|
2007-12-17 |
2013-11-06 |
アンワイヤード プラネット エルエルシー |
多アンテナ受信機干渉除去方法及び装置
|
|
EP2072525A1
(en)
|
2007-12-21 |
2009-06-24 |
Affibody AB |
New polypeptides having affinity for HER2
|
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
|
EP2268297A4
(en)
|
2008-02-29 |
2011-11-16 |
Angelica Therapeutics Inc |
MODIFIED TOXINS
|
|
ES2342646B1
(es)
|
2008-06-02 |
2011-04-26 |
Institut De Recerca Hospital Universitari Vall Hebron |
Metodo de diagnostico de canceres que expresan el receptor her-2 o sus variantes truncadas.
|
|
JP6049163B2
(ja)
|
2008-07-21 |
2016-12-21 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
改善された治療上の特徴のための抗体の構造変異体
|
|
US20110280913A1
(en)
|
2008-07-31 |
2011-11-17 |
The Ohio State University |
Methods and Compositions for Delivering Therapeutic Agents in the Treatment of B-Cell Related Disorders
|
|
US20100093563A1
(en)
|
2008-09-22 |
2010-04-15 |
Robert Anthony Williamson |
Methods and vectors for display of molecules and displayed molecules and collections
|
|
KR101832499B1
(ko)
|
2009-01-23 |
2018-02-26 |
더 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신, 인코포레이티드 |
시가 독소 2형 단백질 기반 방법 및 조성물
|
|
US9034341B2
(en)
|
2009-04-20 |
2015-05-19 |
Transtech Pharma, Llc |
Control of RAGE fusion protein glycosylation and RAGE fusion protein compositions
|
|
US20120258104A1
(en)
|
2009-07-22 |
2012-10-11 |
Cenix Bioscience Gmbh |
Delivery System and Conjugates For Compound Delivery Via Naturally Occurring Intracellular Transport Routes
|
|
EP2464836A2
(en)
|
2009-08-14 |
2012-06-20 |
Unifrax I LLC |
Mounting mat for exhaust gas treatment device
|
|
EP2371864A1
(en)
|
2010-03-23 |
2011-10-05 |
Ganymed Pharmaceuticals AG |
Monoclonal antibodies for treatment of cancer
|
|
KR20130108069A
(ko)
|
2010-04-15 |
2013-10-02 |
알퍼 바이오테크, 엘엘씨 |
Her2 항원에 대한 모노클로날 항체 및 그를 위한 용도
|
|
CN114805583A
(zh)
|
2010-05-27 |
2022-07-29 |
根马布股份公司 |
针对her2的单克隆抗体
|
|
GB201013989D0
(en)
|
2010-08-20 |
2010-10-06 |
Univ Southampton |
Biological materials and methods of using the same
|
|
PL219845B1
(pl)
|
2011-01-05 |
2015-07-31 |
Adamed Spółka Z Ograniczoną Odpowiedzialnością |
Przeciwnowotworowe białko fuzyjne
|
|
CA2825023A1
(en)
|
2011-01-26 |
2012-08-02 |
Cenix Bioscience Gmbh |
Delivery system and conjugates for compound delivery via naturally occurring intracellular transport routes
|
|
WO2012104344A1
(en)
|
2011-02-01 |
2012-08-09 |
Genmab A/S |
Human antibodies and antibody-drug conjugates against cd74
|
|
US8895006B2
(en)
|
2011-03-04 |
2014-11-25 |
Rutgers, The State University Of New Jersey |
Ricin ribosome binding protein compositions and methods of use thereof
|
|
RU2600067C2
(ru)
|
2011-05-06 |
2016-10-20 |
Дзе Гавермент Оф Дзе Юнайтед Стейтс Оф Америка Эз Репрезентед Бай Дзе Секретари Оф Дзе Депармент Оф Хелс Энд Хьюман Сёрвисез |
Рекомбинантный иммунотоксин, нацеленный на мезотелин
|
|
PL397167A1
(pl)
|
2011-11-28 |
2013-06-10 |
Adamed Spólka Z Ograniczona Odpowiedzialnoscia |
Przeciwnowotworowe bialko fuzyjne
|
|
EP2817341A4
(en)
|
2012-02-23 |
2015-12-02 |
Harvard College |
MICROBIAL MODIFIED TOXIN RECEPTOR FOR THE DISTRIBUTION OF AGENTS IN CELLS
|
|
RS60280B1
(sr)
|
2013-03-12 |
2020-06-30 |
Molecular Templates Inc |
Citotoksični proteini koji sadrže ciljane vezujuće regione za ćelije i regioni shiga toksina a podjedinice za selektivno ubijanje određenih vrsta ćelija
|
|
GB2519786A
(en)
|
2013-10-30 |
2015-05-06 |
Sergej Michailovic Kiprijanov |
Multivalent antigen-binding protein molecules
|
|
US20160177284A1
(en)
|
2014-01-27 |
2016-06-23 |
Molecular Templates, Inc. |
Cell-targeted molecules comprising amino-terminus proximal or amino-terminal shiga toxin a subunit effector regions
|
|
CN111909278B
(zh)
|
2014-01-27 |
2024-04-09 |
分子模板公司 |
Mhc i类表位递送多肽
|
|
WO2017019623A2
(en)
*
|
2015-07-26 |
2017-02-02 |
Molecular Templates, Inc. |
Cell-targeting molecules comprising shiga toxin a subunit effectors and cd8+ t-cell epitopes
|
|
US20210138076A2
(en)
|
2014-01-27 |
2021-05-13 |
Molecular Templates, Inc. |
Cell-targeting molecules comprising shiga toxin a subunit effectors and cd8+ t-cell epitopes
|
|
US10421958B2
(en)
|
2014-02-05 |
2019-09-24 |
Molecular Templates, Inc. |
Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicity
|
|
AU2015229583B2
(en)
|
2014-03-11 |
2020-07-09 |
Molecular Templates, Inc. |
Proteins comprising amino-terminal proximal Shiga toxin A Subunit effector regions and cell-targeting immunoglobulin-type binding regions
|
|
ES2723774T3
(es)
|
2014-03-11 |
2019-09-02 |
Molecular Templates Inc |
Proteínas que comprenden regiones de unión, regiones efectoras de la subunidad A de toxina Shiga y motivos señal de localización de retículo endoplasmático carboxi terminal
|
|
US11142584B2
(en)
|
2014-03-11 |
2021-10-12 |
Molecular Templates, Inc. |
CD20-binding proteins comprising Shiga toxin A subunit effector regions for inducing cellular internalization and methods using same
|
|
JP6643545B2
(ja)
|
2014-03-14 |
2020-02-12 |
ラクオリア創薬株式会社 |
Trpm8拮抗剤としてのアザスピロ誘導体
|
|
ES2919749T3
(es)
|
2014-06-11 |
2022-07-28 |
Molecular Templates Inc |
Moléculas dirigidas a células citotóxicas resistentes a la escisión por proteasa
|
|
EP3157958B1
(en)
|
2014-06-18 |
2020-05-06 |
Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus |
Car-expressing nk-92 cells as cell therapeutic agents
|
|
CN105713087B
(zh)
|
2014-11-12 |
2020-05-08 |
北京康乐卫士生物技术股份有限公司 |
人乳头瘤病毒58型单克隆抗体及其应用
|
|
MX2017010072A
(es)
|
2015-02-05 |
2017-11-09 |
Molecular Templates Inc |
Moleculas multivalentes que se enlazan a cd20, las cuales comprenden regiones efectoras de la subunidad a de la toxina shiga, y composiciones enriquecidas de las mismas.
|
|
KR102357312B1
(ko)
|
2015-03-04 |
2022-02-03 |
아이쥐엠 바이오사이언스 인코포레이티드 |
Cd20 결합 분자 및 그의 용도
|
|
AU2016271124C1
(en)
*
|
2015-05-30 |
2020-05-14 |
Molecular Templates, Inc. |
De-immunized, Shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
|
|
EP3202783A1
(en)
|
2016-02-02 |
2017-08-09 |
Ecole Polytechnique Fédérale de Lausanne (EPFL) |
Engineered antigen presenting cells and uses thereof
|
|
KR102418372B1
(ko)
|
2016-03-29 |
2022-07-08 |
주식회사 에스티큐브 |
글리코실화된 pd-l1에 특이적인 이중 기능 항체 및 이의 사용 방법
|
|
EP3448874A4
(en)
|
2016-04-29 |
2020-04-22 |
Voyager Therapeutics, Inc. |
COMPOSITIONS FOR TREATING A DISEASE
|
|
CN117088979A
(zh)
|
2016-10-30 |
2023-11-21 |
上海复宏汉霖生物技术股份有限公司 |
抗-pd-l1抗体及变异体
|
|
WO2018106895A1
(en)
*
|
2016-12-07 |
2018-06-14 |
Molecular Templates, Inc. |
Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
|
|
WO2018124642A2
(ko)
|
2016-12-26 |
2018-07-05 |
단국대학교 천안캠퍼스 산학협력단 |
치수줄기세포의 상아 모전구세포로의 분화용 조성물 및 상아모전구세포 표면에 특이적으로 결합하는 IgG 또는 IgM 타입 단일 클론 항체
|
|
AU2018211064A1
(en)
|
2017-01-18 |
2019-09-05 |
Genentech, Inc. |
Idiotypic antibodies against anti-PD-L1 antibodies and uses thereof
|
|
EP3573648B1
(en)
|
2017-01-25 |
2023-11-22 |
Molecular Templates, Inc. |
Cell-targeting molecules comprising de-immunized, shiga toxin a subunit effectors and cd8+ t-cell epitopes
|
|
US20200190138A1
(en)
|
2017-02-28 |
2020-06-18 |
Chugai Seiyaku Kabushiki Kaisha |
Protein purification with protein l
|
|
BR112019018533A2
(pt)
|
2017-03-09 |
2020-04-14 |
Genmab A/S |
anticorpo, construção de ácido nucleico, vetor de expressão, célula hospedeira, composição farmacêutica, método para tratar uma doença, e, uso de um anticorpo
|
|
BR112019020185A2
(pt)
|
2017-03-27 |
2020-06-02 |
Celgene Corporation |
Métodos e composições para redução da imunogenicidade
|
|
CN111108113B
(zh)
|
2017-09-25 |
2024-02-23 |
Jsr株式会社 |
免疫球蛋白结合蛋白质和使用其的亲和载体
|
|
WO2019183093A1
(en)
|
2018-03-19 |
2019-09-26 |
Abeome Corporation |
High affinity neutralizing monoclonal antibodies to programmed death ligand 1 (pd-l1) and uses thereof
|
|
AU2019257343A1
(en)
|
2018-04-17 |
2020-09-10 |
Molecular Templates, Inc. |
HER2-targeting molecules comprising de-immunized, Shiga toxin A Subunit scaffolds
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
WO2020154475A1
(en)
|
2019-01-23 |
2020-07-30 |
Molecular Templates, Inc. |
Proteins comprising modified immunoglobulin variable light chains
|