JP2025038088A5 - - Google Patents
Info
- Publication number
- JP2025038088A5 JP2025038088A5 JP2024218813A JP2024218813A JP2025038088A5 JP 2025038088 A5 JP2025038088 A5 JP 2025038088A5 JP 2024218813 A JP2024218813 A JP 2024218813A JP 2024218813 A JP2024218813 A JP 2024218813A JP 2025038088 A5 JP2025038088 A5 JP 2025038088A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- set forth
- protein functional
- linker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010324783.4 | 2020-04-22 | ||
| CN202010324783 | 2020-04-22 | ||
| CN202110270671 | 2021-03-12 | ||
| CN202110270671.X | 2021-03-12 | ||
| JP2022564073A JP7763780B2 (ja) | 2020-04-22 | 2021-04-22 | 抗ｃｄ７３／抗ｐｄ－１二重特異性抗体及びその使用 |
| PCT/CN2021/089059 WO2021213475A1 (zh) | 2020-04-22 | 2021-04-22 | 抗cd73-抗pd-1双特异性抗体及其用途 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022564073A Division JP7763780B2 (ja) | 2020-04-22 | 2021-04-22 | 抗ｃｄ７３／抗ｐｄ－１二重特異性抗体及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025038088A JP2025038088A (ja) | 2025-03-18 |
| JP2025038088A5 true JP2025038088A5 (https=) | 2026-02-04 |
Family
ID=78094648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022564073A Active JP7763780B2 (ja) | 2020-04-22 | 2021-04-22 | 抗ｃｄ７３／抗ｐｄ－１二重特異性抗体及びその使用 |
| JP2024218813A Pending JP2025038088A (ja) | 2020-04-22 | 2024-12-13 | 抗ｃｄ７３／抗ｐｄ－１二重特異性抗体及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022564073A Active JP7763780B2 (ja) | 2020-04-22 | 2021-04-22 | 抗ｃｄ７３／抗ｐｄ－１二重特異性抗体及びその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230151111A1 (https=) |
| EP (1) | EP4141033A4 (https=) |
| JP (2) | JP7763780B2 (https=) |
| KR (1) | KR20230004726A (https=) |
| CN (1) | CN113527501B (https=) |
| AU (1) | AU2021261803B2 (https=) |
| BR (1) | BR112022021426A2 (https=) |
| CA (1) | CA3176321A1 (https=) |
| IL (1) | IL297432A (https=) |
| MX (1) | MX2022013311A (https=) |
| PH (1) | PH12022552785A1 (https=) |
| WO (1) | WO2021213475A1 (https=) |
| ZA (1) | ZA202211405B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020324185A1 (en) * | 2019-08-02 | 2022-03-03 | CTTQ-Akeso (ShangHai) Biomed. Tech. Co., Ltd. | Anti-PD-1 antibody and medical use thereof |
| US20240018254A1 (en) * | 2020-10-23 | 2024-01-18 | Akeso Biopharma, Inc | Anti-cd73 antibody and use thereof |
| CN118530341A (zh) * | 2021-03-12 | 2024-08-23 | 中山康方生物医药有限公司 | 提高含有免疫球蛋白Fc片段的药物的有效性的方法 |
| CN119173276A (zh) | 2022-04-13 | 2024-12-20 | 吉利德科学公司 | 用于治疗表达Trop-2的癌症的组合疗法 |
| JP2025520232A (ja) * | 2022-06-22 | 2025-07-03 | 中山康方生物医▲藥▼有限公司 | 医薬組成物及びその使用 |
| CN116813786B (zh) * | 2023-08-03 | 2024-11-26 | 贝达药业股份有限公司 | 抗cd73抗体及其应用 |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JP2013532153A (ja) * | 2010-06-18 | 2013-08-15 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 慢性免疫病に対する免疫治療のためのｔｉｍ−３およびｐｄ−１に対する二重特異性抗体 |
| DK3218406T4 (da) * | 2014-11-10 | 2024-12-09 | Medimmune Ltd | Bindingsmolekyler, der er specifikke for cd73, og anvendelser deraf |
| EP3218407A1 (en) | 2014-11-11 | 2017-09-20 | Medimmune Limited | Therapeutic combinations comprising anti-cd73 antibodies and a2a receptor inhibitor and uses thereof |
| MY189836A (en) * | 2014-11-21 | 2022-03-11 | Bristol Myers Squibb Co | Antibodies against cd73 and uses thereof |
| AU2016334051B2 (en) * | 2015-10-06 | 2023-10-26 | Alector Llc | Anti-TREM2 antibodies and methods of use thereof |
| KR102799807B1 (ko) * | 2015-12-30 | 2025-04-24 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| KR20230038311A (ko) * | 2016-03-04 | 2023-03-17 | 브리스톨-마이어스 스큅 컴퍼니 | 항-cd73 항체와의 조합 요법 |
| TWI693940B (zh) * | 2016-08-05 | 2020-05-21 | 日商中外製藥股份有限公司 | Ｉｌ-８相關疾病之治療用或預防用組成物 |
| CN106977602B (zh) * | 2016-08-23 | 2018-09-25 | 中山康方生物医药有限公司 | 一种抗pd1单克隆抗体、其药物组合物及其用途 |
| CN106967172B (zh) * | 2016-08-23 | 2019-01-08 | 康方药业有限公司 | 抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途 |
| CN111565722A (zh) * | 2017-11-06 | 2020-08-21 | 科尔沃斯制药股份有限公司 | 用于癌症治疗的腺苷路径抑制剂 |
| KR102804816B1 (ko) * | 2018-03-09 | 2025-05-09 | 페인스 테라퓨틱스 인코포레이티드 | 항-cd73 항체 및 이의 용도 |
| US20210147570A1 (en) * | 2018-04-12 | 2021-05-20 | Bristol-Myers Squibb Company | Anticancer combination therapy with cd73 antagonist antibody and pd-1/pd-l1 axis antagonist antibody |
| WO2020020307A1 (en) * | 2018-07-25 | 2020-01-30 | I-Mab Biopharma Co., Ltd. | Anti-cd73 anti-pd-l1 bispecific antibodies |
| CN109053895B (zh) * | 2018-08-30 | 2020-06-09 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途 |
| BR112022021397A2 (pt) * | 2020-04-22 | 2023-02-07 | Akeso Biopharma Inc | Anticorpo anti-cd73, polipeptídeo isolado, molécula de ácido nucleico, vetor, célula hospedeira, conjugado, proteína de fusão ou anticorpo multiespecífico, kit, composição farmacêutica, uso do anticorpo e linhagem celular de hibridoma |
-
2021
- 2021-04-22 KR KR1020227040580A patent/KR20230004726A/ko not_active Ceased
- 2021-04-22 IL IL297432A patent/IL297432A/en unknown
- 2021-04-22 US US17/996,878 patent/US20230151111A1/en active Pending
- 2021-04-22 PH PH1/2022/552785A patent/PH12022552785A1/en unknown
- 2021-04-22 BR BR112022021426A patent/BR112022021426A2/pt unknown
- 2021-04-22 CN CN202110440285.0A patent/CN113527501B/zh active Active
- 2021-04-22 EP EP21792313.5A patent/EP4141033A4/en active Pending
- 2021-04-22 JP JP2022564073A patent/JP7763780B2/ja active Active
- 2021-04-22 WO PCT/CN2021/089059 patent/WO2021213475A1/zh not_active Ceased
- 2021-04-22 CA CA3176321A patent/CA3176321A1/en active Pending
- 2021-04-22 MX MX2022013311A patent/MX2022013311A/es unknown
- 2021-04-22 AU AU2021261803A patent/AU2021261803B2/en active Active
-
2022
- 2022-10-18 ZA ZA2022/11405A patent/ZA202211405B/en unknown
-
2024
- 2024-12-13 JP JP2024218813A patent/JP2025038088A/ja active Pending
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