JP2010535713A5 - - Google Patents

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Publication number
JP2010535713A5
JP2010535713A5 JP2010519276A JP2010519276A JP2010535713A5 JP 2010535713 A5 JP2010535713 A5 JP 2010535713A5 JP 2010519276 A JP2010519276 A JP 2010519276A JP 2010519276 A JP2010519276 A JP 2010519276A JP 2010535713 A5 JP2010535713 A5 JP 2010535713A5
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JP
Japan
Prior art keywords
seq
antibody
region
antigen
binding fragment
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2010519276A
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English (en)
Japanese (ja)
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JP2010535713A (ja
JP5409628B2 (ja
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Priority claimed from PCT/US2008/072146 external-priority patent/WO2009020933A2/en
Publication of JP2010535713A publication Critical patent/JP2010535713A/ja
Publication of JP2010535713A5 publication Critical patent/JP2010535713A5/ja
Application granted granted Critical
Publication of JP5409628B2 publication Critical patent/JP5409628B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010519276A 2007-08-03 2008-08-04 抗ｔｗｅａｋ受容体抗体の治療上の使用 Expired - Fee Related JP5409628B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95374507P 2007-08-03 2007-08-03
US60/953,745 2007-08-03
US12362308P 2008-04-09 2008-04-09
US61/123,623 2008-04-09
PCT/US2008/072146 WO2009020933A2 (en) 2007-08-03 2008-08-04 Therapeutic use of anti-tweak receptor antibodies

Publications (3)

Publication Number Publication Date
JP2010535713A JP2010535713A (ja) 2010-11-25
JP2010535713A5 true JP2010535713A5 (https=) 2011-09-22
JP5409628B2 JP5409628B2 (ja) 2014-02-05

Family

ID=40193427

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010519276A Expired - Fee Related JP5409628B2 (ja) 2007-08-03 2008-08-04 抗ｔｗｅａｋ受容体抗体の治療上の使用

Country Status (12)

Country Link
US (1) US9056908B2 (https=)
EP (2) EP2545938A1 (https=)
JP (1) JP5409628B2 (https=)
KR (1) KR20100053607A (https=)
CN (1) CN102006886A (https=)
BR (1) BRPI0814768A2 (https=)
CA (1) CA2694751C (https=)
ES (1) ES2411907T3 (https=)
IL (1) IL203038A (https=)
MX (1) MX2010001378A (https=)
NZ (1) NZ582815A (https=)
WO (1) WO2009020933A2 (https=)

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JP6971858B2 (ja) 2015-06-22 2021-11-24 バイエル ファーマ アクチエンゲゼルシャフト 酵素開裂性基を有する抗体薬物複合体（ａｄｃ）および抗体プロドラッグ複合体（ａｐｄｃ）
WO2016207104A1 (de) * 2015-06-23 2016-12-29 Bayer Pharma Aktiengesellschaft Antikörper-wirkstoff-konjugate (adcs) von ksp-inhibitoren mit anti-b7h3-antikörpern
EP3313523A2 (en) 2015-06-23 2018-05-02 Bayer Pharma Aktiengesellschaft Targeted conjugates of ksp inhibitors
EP3313521A1 (de) 2015-06-23 2018-05-02 Bayer Pharma Aktiengesellschaft Antikörper-wirkstoff-konjugate (adcs) von ksp-inhibitoren mit anti-tweakr-antikörpern
WO2017060322A2 (en) 2015-10-10 2017-04-13 Bayer Pharma Aktiengesellschaft Ptefb-inhibitor-adc
JP7251981B2 (ja) 2016-03-24 2023-04-04 バイエル ファーマ アクチエンゲゼルシャフト 酵素開裂基を有する細胞毒性活性剤のプロドラッグ
EP3919518A1 (en) 2016-06-15 2021-12-08 Bayer Pharma Aktiengesellschaft Specific antibody-drug-conjugates (adcs) with ksp inhibitors and anti-cd123-antibodies
CN110312534B (zh) 2016-12-21 2023-04-04 拜耳制药股份公司 具有酶促可裂解基团的抗体-药物-缀合物(adc)
CN110072556B (zh) 2016-12-21 2023-05-02 拜耳制药股份公司 具有ksp抑制剂的特异性抗体药物缀合物(adc)
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