JPS6340546B2 - - Google Patents

Info

Publication number
JPS6340546B2
JPS6340546B2 JP55013782A JP1378280A JPS6340546B2 JP S6340546 B2 JPS6340546 B2 JP S6340546B2 JP 55013782 A JP55013782 A JP 55013782A JP 1378280 A JP1378280 A JP 1378280A JP S6340546 B2 JPS6340546 B2 JP S6340546B2
Authority
JP
Japan
Prior art keywords
fibrinogen
inhibitor
factor
tissue adhesive
lyophilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55013782A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55110556A (en
Inventor
Shuarutsu Otsutoo
Rinnau Iendora
Reepuritsuhi Furantsu
Zeeritsuhi Toomasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMUNOO AG FUIA HIEEMITSUSHUUMEDEITSUIINITSUSHE PURODAKUTE
Original Assignee
IMUNOO AG FUIA HIEEMITSUSHUUMEDEITSUIINITSUSHE PURODAKUTE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3508534&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS6340546(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by IMUNOO AG FUIA HIEEMITSUSHUUMEDEITSUIINITSUSHE PURODAKUTE filed Critical IMUNOO AG FUIA HIEEMITSUSHUUMEDEITSUIINITSUSHE PURODAKUTE
Publication of JPS55110556A publication Critical patent/JPS55110556A/ja
Publication of JPS6340546B2 publication Critical patent/JPS6340546B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/005Enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • A61L24/106Fibrin; Fibrinogen
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/829Blood
    • Y10S530/83Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP1378280A 1979-02-15 1980-02-08 Tissue adhesive and its preparation Granted JPS55110556A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT118979A AT359652B (de) 1979-02-15 1979-02-15 Verfahren zur herstellung eines gewebekleb- stoffes

Publications (2)

Publication Number Publication Date
JPS55110556A JPS55110556A (en) 1980-08-26
JPS6340546B2 true JPS6340546B2 (enExample) 1988-08-11

Family

ID=3508534

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1378280A Granted JPS55110556A (en) 1979-02-15 1980-02-08 Tissue adhesive and its preparation

Country Status (14)

Country Link
US (2) US4362567A (enExample)
JP (1) JPS55110556A (enExample)
AT (1) AT359652B (enExample)
BE (1) BE881466A (enExample)
CA (1) CA1128859A (enExample)
CH (1) CH649711A5 (enExample)
DE (1) DE3002934C2 (enExample)
DK (1) DK150815B (enExample)
ES (1) ES488430A0 (enExample)
FR (1) FR2448900A1 (enExample)
GB (1) GB2041942B (enExample)
IT (1) IT1141211B (enExample)
NL (1) NL190714B (enExample)
SE (2) SE453799C (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010063504A (ja) * 2008-09-09 2010-03-25 Chemo Sero Therapeut Res Inst カルボン酸含有生体組織接着剤及びその調製方法
US9775884B2 (en) 2007-03-22 2017-10-03 The Chemo-Sero-Therapeutic Research Institute Solid fibrinogen preparation

Families Citing this family (198)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT359652B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
DE3105624A1 (de) * 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
EP0068149A3 (de) * 1981-06-25 1983-07-20 Serapharm GmbH & Co. KG Fibrinogen-haltiges Trockenpräparat, dessen Herstellung und Verwendung
US4442655A (en) * 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
ATE20824T1 (de) 1981-06-25 1986-08-15 Serapharm Gmbh & Co Kg Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundheilung.
DE3171072D1 (en) * 1981-06-25 1985-07-25 Stroetmann M Serapharm Enriched plasma derivative for promoting wound sealing and wound covering
AT369990B (de) * 1981-07-28 1983-02-25 Immuno Ag Verfahren zur herstellung eines gewebeklebstoffes
DE3203775A1 (de) * 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
DE3214337C2 (de) * 1982-04-19 1984-04-26 Serapharm - Michael Stroetmann, 4400 Münster Resorbierbares Flachmaterial zum Abdichten und Heilen von Wunden und Verfahren zu dessen Herstellung
US4515637A (en) * 1983-11-16 1985-05-07 Seton Company Collagen-thrombin compositions
JP2648301B2 (ja) * 1983-12-27 1997-08-27 ジエネテイツクス・インスチチユ−ト・インコ−ポレ−テツド 真核細胞の形質転換のための補助dnaを含むベクター
US4600574A (en) * 1984-03-21 1986-07-15 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Method of producing a tissue adhesive
EP0166263A1 (en) * 1984-05-31 1986-01-02 Green Cross Corporation Filler composition for filling in defect or hollow portion of bone and kit or set for the preparation of the filler composition
US4627879A (en) * 1984-09-07 1986-12-09 The Trustees Of Columbia University In The City Of New York Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma
US4928603A (en) * 1984-09-07 1990-05-29 The Trustees Of Columbia University In The City Of New York Method of preparing a cryoprecipitated suspension and use thereof
AT390001B (de) * 1984-09-28 1990-03-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern
AT382783B (de) * 1985-06-20 1987-04-10 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
JPS6323670A (ja) * 1986-04-25 1988-01-30 バイオ−ポリマ−ズ インコ−ポレ−テツド 接着・被覆組成物とその使用方法
DE3622642A1 (de) * 1986-07-05 1988-01-14 Behringwerke Ag Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
DK475386D0 (da) * 1986-10-03 1986-10-03 Weis Fogh Ulla Sivertsen Fremgangsmaade og apparat til fremstilling af biologiske stoffer
CH673117A5 (enExample) * 1986-12-10 1990-02-15 Ajinomoto Kk
US5260420A (en) * 1987-07-30 1993-11-09 Centre Regional De Transfusion Sanguine De Lille Concentrate of thrombin coagulable proteins, the method of obtaining same and therapeutical use thereof
FR2618784B1 (fr) * 1987-07-30 1990-04-06 Lille Transfusion Sanguine Concentre de proteines coagulables par la thrombine, son procede d'obtention et son utilisation a titre de colle biologique
AT407834B (de) * 1987-10-08 2001-06-25 Aventis Behring Gmbh Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
ATE111360T1 (de) * 1988-05-02 1994-09-15 Project Hear Chirurgisches klebstoffmaterial.
AT397203B (de) * 1988-05-31 1994-02-25 Immuno Ag Gewebeklebstoff
US4837379A (en) * 1988-06-02 1989-06-06 Organogenesis Inc. Fibrin-collagen tissue equivalents and methods for preparation thereof
DE3829524A1 (de) * 1988-08-31 1990-03-01 Behringwerke Ag Verwendung von transglutaminasen als immunsuppressiva
FR2639958B1 (fr) * 1988-12-06 1992-08-21 Lille Transfusion Sanguine Support biologique pour cultures cellulaires constitue de proteines plasmatiques coagulees par la thrombine, son utilisation pour la culture des keratinocytes, leur recuperation et leur transport a des fins d'utilisation therapeutique
US5226877A (en) * 1989-06-23 1993-07-13 Epstein Gordon H Method and apparatus for preparing fibrinogen adhesive from whole blood
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5209776A (en) * 1990-07-27 1993-05-11 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5420250A (en) * 1990-08-06 1995-05-30 Fibrin Corporation Phase transfer process for producing native plasma protein concentrates
US5644032A (en) * 1990-08-06 1997-07-01 Fibrin Corporation Process for producing fibrinogen concentrates
US7229959B1 (en) 1990-11-27 2007-06-12 The American National Red Cross Supplemented fibrin matrix delivery systems
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
JP3604688B2 (ja) * 1990-11-27 2004-12-22 ジ・アメリカン・ナショナル・レッド・クロス 加速された傷の治癒を促進する組織シーラントおよび成長因子含有組成物
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
US6093558A (en) * 1991-07-25 2000-07-25 Edge Biosystems, Inc. Binding protein of biologically active compositions to an adhesive formulation on a substrate
EP0602173B1 (en) * 1991-09-05 1999-05-26 Baxter International Inc. Topical fibrinogen complex
WO1993005822A1 (en) * 1991-09-27 1993-04-01 Octapharma Ag Tissue glue prepared by using cryoprecipitate
US5190057A (en) * 1991-12-13 1993-03-02 Faezeh Sarfarazi Sarfarazi method of closing a corneal incision
US5385606A (en) * 1992-07-06 1995-01-31 Kowanko; Nicholas Adhesive composition and method
FR2696095B1 (fr) * 1992-09-30 1994-11-25 Inoteb Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application.
US5395923A (en) * 1993-02-23 1995-03-07 Haemacure-Biotech, Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
US5290918A (en) * 1993-02-23 1994-03-01 Haemacure Biotech Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by acidic precipitation
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
US5552452A (en) * 1993-03-15 1996-09-03 Arch Development Corp. Organic tissue glue for closure of wounds
FR2705235B1 (fr) * 1993-05-13 1995-07-13 Inoteb Utilisation de particules d'un sel de calcium biocompatible et biorésorbable comme ingrédient actif dans la préparation d'un médicament destiné au traitement local des maladies déminéralisantes de l'os.
US5843124A (en) 1993-09-28 1998-12-01 Hemodynamics, Inc. Surface opening adhesive sealer
US5759194A (en) * 1993-09-28 1998-06-02 Hemodynamics, Inc. Vascular patch applicator
US5653730A (en) * 1993-09-28 1997-08-05 Hemodynamics, Inc. Surface opening adhesive sealer
DE69433939T2 (de) * 1993-11-03 2005-08-11 Clarion Pharmaceuticals, Inc., Madison Hämostatisches pflaster
US5411885A (en) * 1993-12-17 1995-05-02 New York Blood Center, Inc. Methods for tissue embedding and tissue culturing
US5639940A (en) 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
WO1995026749A1 (en) * 1994-03-31 1995-10-12 Fibrin Corporation Cryoprecipitated native fibrinogen concentrates
US5583114A (en) 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
USRE38827E1 (en) 1994-07-27 2005-10-11 3M Innovative Properties Company Adhesive sealant composition
US5660873A (en) * 1994-09-09 1997-08-26 Bioseal, Limited Liability Corporaton Coating intraluminal stents
EP0745670B1 (en) * 1994-10-11 2004-06-23 Ajinomoto Co., Inc. Stabilized transglutaminase and enzymatic preparation containing the same
US5464471A (en) * 1994-11-10 1995-11-07 Whalen Biomedical Inc. Fibrin monomer based tissue adhesive
US5585007A (en) 1994-12-07 1996-12-17 Plasmaseal Corporation Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
WO1996022115A1 (en) * 1995-01-16 1996-07-25 Baxter International Inc. Self-supporting sheet-like material of cross-linked fibrin for preventing post operative adhesions
US5733545A (en) * 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant
US5674394A (en) * 1995-03-24 1997-10-07 Johnson & Johnson Medical, Inc. Single use system for preparation of autologous plasma
US5643192A (en) * 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
WO1996039208A1 (en) 1995-06-06 1996-12-12 Quantic Biomedical Partners Device and method for concentrating plasma
DE19521324C1 (de) * 1995-06-12 1996-10-31 Immuno Ag Gewebeklebstoff und Verwendung desselben als Hämostyptikum
US5733884A (en) * 1995-11-07 1998-03-31 Nestec Ltd. Enteral formulation designed for optimized wound healing
AU715822B2 (en) 1996-03-15 2000-02-10 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Tissue adhesive suitable for spray application
WO2000062828A1 (en) 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
DE19617369A1 (de) * 1996-04-30 1997-11-06 Immuno Ag Lagerstabile Fibrinogen-Präparate
EP0917444A1 (en) 1996-07-12 1999-05-26 Baxter Travenol Laboratories, Inc. A fibrin delivery device and method for forming fibrin on a surface
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US20090324721A1 (en) 1996-09-23 2009-12-31 Jack Kennedy Hydrogels Suitable For Use In Polyp Removal
US7009034B2 (en) * 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US8003705B2 (en) 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
WO1998012274A1 (en) * 1996-09-23 1998-03-26 Chandrashekar Pathak Methods and devices for preparing protein concentrates
FR2757770B1 (fr) * 1996-12-30 1999-02-26 Inoteb Procede de preparation d'une colle biologique capable de coaguler par simple addition d'ions calcium
US6096309A (en) * 1997-06-18 2000-08-01 Cohesion Technologies, Inc. Compositions containing thrombin and microfibrillar nanometer collagen, and methods for preparation and use thereof
AT406120B (de) 1997-08-28 2000-02-25 Immuno Ag Gewebekleber
DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
US6762336B1 (en) 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
US6884230B1 (en) 1998-03-09 2005-04-26 Baxter International Inc. Dispensing head for a tissue sealant applicator and process of use
US6274090B1 (en) 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
US6994686B2 (en) * 1998-08-26 2006-02-07 Neomend, Inc. Systems for applying cross-linked mechanical barriers
US6921380B1 (en) 1998-10-01 2005-07-26 Baxter International Inc. Component mixing catheter
BE1012536A3 (fr) 1998-11-04 2000-12-05 Baxter Int Element muni d'une couche de fibrine sa preparation et son utilisation.
US7279001B2 (en) * 1998-11-06 2007-10-09 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
JP2003517997A (ja) 1998-11-12 2003-06-03 ポリマー・バイオサイエンシス,インコーポレイテッド 急速な血液凝集及び止血に有用な止血ポリマー
AU2707500A (en) * 1998-12-04 2000-06-26 Incept Llc Biocompatible crosslinked polymers
US6310036B1 (en) 1999-01-09 2001-10-30 Last Chance Tissue Adhesives Corporation High strength, Bio-compatible tissue adhesive and methods for treating vigorously bleeding surfaces
US7662179B2 (en) * 1999-04-09 2010-02-16 Sarfarazi Faezeh M Haptics for accommodative intraocular lens system
US8556967B2 (en) * 1999-04-09 2013-10-15 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector
US20030007954A1 (en) * 1999-04-12 2003-01-09 Gail K. Naughton Methods for using a three-dimensional stromal tissue to promote angiogenesis
US6472162B1 (en) 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
WO2001012244A1 (en) * 1999-08-13 2001-02-22 Omrix Biopharmaceuticals S.A. Use of fibrinogen multimers
US6916911B1 (en) 1999-08-13 2005-07-12 Omrix Biopharmaceuticals Sa Use of fibrinogen multimers
US7078232B2 (en) * 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US6429013B1 (en) 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6463335B1 (en) 1999-10-04 2002-10-08 Medtronic, Inc. Temporary medical electrical lead having electrode mounting pad with biodegradable adhesive
WO2001048016A1 (en) * 1999-12-23 2001-07-05 Csl Limited Separation of fibrinogen from plasma proteases
WO2002005898A1 (en) * 2000-07-17 2002-01-24 Haemacure Corporation Spray head for applying a multi-component mixture
US7326412B2 (en) * 2000-10-13 2008-02-05 Baxter International Inc. Fibrinogen plus a non-plasmin-acting fibrinolysis inhibitor for the reduction or prevention of adhesion formation
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
US20020082620A1 (en) * 2000-12-27 2002-06-27 Elaine Lee Bioactive materials for aneurysm repair
US6468660B2 (en) 2000-12-29 2002-10-22 St. Jude Medical, Inc. Biocompatible adhesives
US7175336B2 (en) 2001-01-26 2007-02-13 Depuy Acromed, Inc. Graft delivery system
US7795218B2 (en) 2001-04-12 2010-09-14 Bioaxone Therapeutique Inc. ADP-ribosyl transferase fusion variant proteins
US20020173770A1 (en) * 2001-05-16 2002-11-21 Flory Alan R. Adhesive delivery system
MXPA04006438A (es) 2001-12-31 2005-06-08 Ares Lab Llc Composiciones hemostaticas y metodos para el control de sangrado.
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US7374678B2 (en) 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
DE10392686T5 (de) 2002-05-24 2005-07-07 Biomet Mfg. Corp., Warsaw Vorrichtung und Verfahren zum Trennen und Konzentrieren von Flüssigkeiten, welche mehrere Komponenten enthalten
CN1327905C (zh) * 2002-09-10 2007-07-25 美国国家红十字会 止血敷料
US7135027B2 (en) 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
US8834864B2 (en) 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US20050125015A1 (en) * 2003-12-04 2005-06-09 Mcnally-Heintzelman Karen M. Tissue-handling apparatus, system and method
US20050125033A1 (en) * 2003-12-04 2005-06-09 Mcnally-Heintzelman Karen M. Wound closure apparatus
TWI270375B (en) * 2004-06-29 2007-01-11 Cheng-Yao Su A method for preserving platelets outside a living body
US7659052B2 (en) * 2004-06-29 2010-02-09 Cheng Yao Su Medium comprising cryoprecipitate and method for preserving platelets, red blood cells and other cells without a nucleus
WO2006005890A1 (fr) * 2004-07-08 2006-01-19 Symatese Colle lyophilisee a base de collagene et son utilisation pour la fabrication de protheses collantes
US20080176789A1 (en) * 2004-08-27 2008-07-24 Novc Nordisk Healthcare A/G Purification of Factor Xlll Polypeptides From Biological Materials
AU2005279934A1 (en) * 2004-08-30 2006-03-09 Theregen, Inc. Compositions and methods of promoting hair growth
WO2006056575A1 (en) 2004-11-23 2006-06-01 Zymogenetics, Inc. Purification of recombinant human factor xiii
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
EP1848474B1 (en) 2005-02-07 2013-06-12 Hanuman LLC Platelet rich plasma concentrate apparatus and method
EP1848472B1 (en) 2005-02-07 2015-04-01 Hanuman LLC Platelet rich plasma concentrate apparatus and method
AU2006213822B2 (en) 2005-02-09 2011-05-26 Covidien Lp Synthetic sealants
TW200714289A (en) * 2005-02-28 2007-04-16 Genentech Inc Treatment of bone disorders
US20060212106A1 (en) * 2005-03-21 2006-09-21 Jan Weber Coatings for use on medical devices
JP2008546686A (ja) * 2005-06-17 2008-12-25 セレゲン,インコーポレーテッド 虚血組織の治療方法
FR2887883B1 (fr) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
FR2894831B1 (fr) 2005-12-16 2008-02-15 Lab Francais Du Fractionnement Colle biologique exempte de thrombine et son utilisation comme medicament.
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
KR20090017654A (ko) 2006-05-31 2009-02-18 백스터 인터내셔널 인코포레이티드 척수 수술에서 세포 내성장을 통제하고 조직 재생을 조절하는 방법
CN101522228A (zh) 2006-08-02 2009-09-02 克赫里昂恩克斯公司 尤其可用于组织填补和瘢痕形成的可植入制剂
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
US20080033331A1 (en) * 2006-08-04 2008-02-07 Macphee Martin Solid dressing for treating wounded tissue
AU2007294808A1 (en) * 2006-09-13 2008-03-20 Southeastern Medical Technologies, Llc Methods and compositions for sealing and adhering biological tissues and medical uses thereof
US20090227981A1 (en) * 2007-03-05 2009-09-10 Bennett Steven L Low-Swelling Biocompatible Hydrogels
US20090227689A1 (en) * 2007-03-05 2009-09-10 Bennett Steven L Low-Swelling Biocompatible Hydrogels
EP2146794B1 (en) 2007-04-12 2016-10-19 Biomet Biologics, LLC Buoy suspension fractionation system
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
WO2009020612A1 (en) * 2007-08-06 2009-02-12 Stb Lifesaving Technologies, Inc. Methods and dressing for sealing internal injuries
CA2703103C (en) 2007-10-30 2017-05-09 Baxter Healthcare S.A. Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects
CN101214391B (zh) * 2007-12-27 2010-05-19 广州倍绣生物技术有限公司 一种高效生物胶封闭剂及其应用
PL2259774T3 (pl) 2008-02-27 2013-04-30 Biomet Biologics Llc Sposoby i kompozycje dla wprowadzania antagonisty receptora interleukiny-1
EP2254991B1 (en) 2008-02-29 2018-08-22 Biomet Manufacturing, LLC A system and process for separating a material
JP5569398B2 (ja) 2008-02-29 2014-08-13 フェッローサン メディカル ディバイス エー/エス 止血および/または創傷治癒を促進するための装置
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
EP2358402A2 (en) 2008-12-11 2011-08-24 Baxter International Inc. Preparations based on fibrinogen and sulfated polysaccharides
US8409606B2 (en) * 2009-02-12 2013-04-02 Incept, Llc Drug delivery through hydrogel plugs
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
KR101699992B1 (ko) 2009-06-16 2017-01-26 백스터 인터내셔널 인코포레이티드 지혈용 스펀지
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
WO2011035020A1 (en) 2009-09-18 2011-03-24 Bioinspire Technologies, Inc. Free-standing biodegradable patch
US9271925B2 (en) 2013-03-11 2016-03-01 Bioinspire Technologies, Inc. Multi-layer biodegradable device having adjustable drug release profile
FR2952641B1 (fr) 2009-11-18 2012-01-13 Lfb Biomedicaments Procede de traitement du plasma sanguin comprenant une etape de lavage par dispersion
JP2013514093A (ja) 2009-12-16 2013-04-25 バクスター・インターナショナル・インコーポレイテッド 止血スポンジ
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
ES2629349T3 (es) 2010-06-01 2017-08-08 Baxter International Inc Procedimiento para obtener composiciones hemostáticas secas y estables
JP6289096B2 (ja) 2010-06-01 2018-03-07 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 乾燥した安定な止血組成物を作製するためのプロセス
KR101814841B1 (ko) 2010-06-01 2018-01-03 백스터 인터내셔널 인코포레이티드 건조 및 안정한 지혈 조성물의 제조 방법
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
JP6195569B2 (ja) 2011-10-11 2017-09-13 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 止血組成物
EP4137164A1 (en) 2011-10-11 2023-02-22 Baxter International Inc. Hemostatic compositions
PL2771027T3 (pl) * 2011-10-27 2016-01-29 Baxter Int Kompozycje hemostatyczne
WO2013131520A2 (en) 2012-03-06 2013-09-12 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
BR112014030962A2 (pt) 2012-06-12 2017-06-27 Ferrosan Medical Devices As métodos para preparação e para reconstituição de uma composição seca adequada para uso em hemostase e cicatrização de feridas, e, kit hemostático
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
BR112015030612B1 (pt) 2013-06-21 2020-07-21 Ferrosan Medical Devices A/S método para preparar uma composição seca
US10111980B2 (en) 2013-12-11 2018-10-30 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
US11046818B2 (en) 2014-10-13 2021-06-29 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
CN107206165B (zh) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 用于保持并混合第一和第二物质的注射器
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
JP6747651B2 (ja) 2015-07-03 2020-08-26 フェロサン メディカル デバイシーズ エイ/エス 保管状態で真空を保持するための、及び2種の成分を混合するためのシリンジ
EP4321182A3 (en) 2018-05-09 2024-05-29 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition
MX2024008243A (es) 2021-12-30 2024-09-04 Baxter Int Soluciones de fibrinogeno y trombina para un sellador de fibrina y un kit de sellador de fibrina.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA448302A (en) * 1948-05-04 Joseph Cohn Edwin Plastic product and process
GB1195061A (en) * 1966-05-27 1970-06-17 Fmc Corp Coated Structures and Methods of Forming Them.
US3523807A (en) * 1966-11-25 1970-08-11 Mihaly Gerendas Method of making a cross-linked fibrin prosthesis
US4265233A (en) * 1978-04-12 1981-05-05 Unitika Ltd. Material for wound healing
AT359652B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes

Non-Patent Citations (14)

* Cited by examiner, † Cited by third party
Title
H P SPANGLER WIENER KLINICHE WOCHENSCHRIFT=1976 *
H P SPANGLER WIENER KLINISCHE WOCHENSCHRIFT=1976 *
ARCH ORTHOP UNFALL CHIR=1977 *
BRITISH JOURNAL OF HAEMATOLOGY=1977 *
DIE MEDIZINISCHE WELT DIE ARZTLICHE FORTBILDUNG=1978 *
DIE MEDIZINISCHE WELT=1978 *
J MAC SURG=1973 *
JAHRESTAGUNG DER DEUTSCHEN ARBEITSGEMEINSCHAFT FUR BLUTGERINNUNGUSFORSCHUNG BLUT=1979 *
L L SHEN BIOCHEM BIOPHY RES COMM=1974 *
LANGENBECKS ARCH CHIR SUPPL CHIR FORUM 1974 *
R MASURE VOX SANG=1969 *
WIENER KLINISCHE WOCHENSCH RIFT=1978 *
WIENER KLINISCHE WOCHENSCHRIFT=1976 *
WIENER KLINISCHE WOCHENSCHRIFT=1976V88 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9775884B2 (en) 2007-03-22 2017-10-03 The Chemo-Sero-Therapeutic Research Institute Solid fibrinogen preparation
JP2010063504A (ja) * 2008-09-09 2010-03-25 Chemo Sero Therapeut Res Inst カルボン酸含有生体組織接着剤及びその調製方法

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DE3002934C2 (de) 1983-12-29
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SE462613B (sv) 1990-07-30
US4414976A (en) 1983-11-15
NL8000935A (nl) 1980-08-19
SE8000469L (sv) 1980-08-16
DK65580A (da) 1980-08-16
SE8902377D0 (sv) 1989-06-30
US4362567A (en) 1982-12-07
ES8101381A1 (es) 1980-12-16
ATA118979A (de) 1980-04-15
SE453799C (sv) 1998-04-06
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GB2041942A (en) 1980-09-17
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GB2041942B (en) 1983-04-13
IT1141211B (it) 1986-10-01
BE881466A (fr) 1980-05-16
CH649711A5 (de) 1985-06-14
FR2448900A1 (fr) 1980-09-12
DE3002934A1 (de) 1980-08-28
FR2448900B1 (enExample) 1984-09-07
SE453799B (sv) 1988-03-07
IT8019910A0 (it) 1980-02-14

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