AR013829A1 - Un dispositivo medico para suministrar cantidades volumetricas de un primer y un segundo fluido, bioquimicamente reactivos, y metodo para suministrarfibrina a una superficie con dicho dispositivo - Google Patents

Un dispositivo medico para suministrar cantidades volumetricas de un primer y un segundo fluido, bioquimicamente reactivos, y metodo para suministrarfibrina a una superficie con dicho dispositivo

Info

Publication number
AR013829A1
AR013829A1 ARP970103073A ARP970103073A AR013829A1 AR 013829 A1 AR013829 A1 AR 013829A1 AR P970103073 A ARP970103073 A AR P970103073A AR P970103073 A ARP970103073 A AR P970103073A AR 013829 A1 AR013829 A1 AR 013829A1
Authority
AR
Argentina
Prior art keywords
fluid
supplying
biochemically
biochemically reactive
medical device
Prior art date
Application number
ARP970103073A
Other languages
English (en)
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/679,658 external-priority patent/US5989215A/en
Application filed by Baxter Int filed Critical Baxter Int
Publication of AR013829A1 publication Critical patent/AR013829A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491Surgical glue applicators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491Surgical glue applicators
    • A61B2017/00495Surgical glue applicators for two-component glue
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0078Arrangements for separately storing several components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02Membranes or pistons acting on the contents inside the container, e.g. follower pistons

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invencion provee un dispositivo médico para suministrar cantidades volumétricas de un primer y de un segundo fluido bioquímicamente reactivos, quecomprende un primer contenedor (12), que tiene una abertura (16), estando el primercontened or (12), adaptado para contener el primer fluidobioquímicamente reactivo; un segundo contenedor (14), que tiene una segunda abertura (16) para fluidos, adyacente a la primera abertura (16) para fluidosestando el segundo contenedor (14),adaptado para contener el segundo fluido bioquímicamente reactivo; una unidad rociadora (18), para atomizar por separadolos fluidos bioquímicamente reactivos primero y segundo, en forma de un aerosol mediante por lo menos una fuente de energíaelegida entr e una energía líquida,una energía mecánica, una energía en forma de vibraciones, y una energía eléctrica; un presurizador para fluidos (22) para presurizar los fluidosbioquímicamente reactivos primero y segundo, para la entregade los mismos b ajo presion a través de la unidad rociadora (18) sobre una superficie (24); y en elcual los fluidos bioquímicamente reactivos primero y segundo se mezclan recién en la superficie (24).
ARP970103073A 1996-07-12 1997-07-10 Un dispositivo medico para suministrar cantidades volumetricas de un primer y un segundo fluido, bioquimicamente reactivos, y metodo para suministrarfibrina a una superficie con dicho dispositivo AR013829A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/679,658 US5989215A (en) 1995-01-16 1996-07-12 Fibrin delivery device and method for forming fibrin on a surface

Publications (1)

Publication Number Publication Date
AR013829A1 true AR013829A1 (es) 2001-01-31

Family

ID=24727815

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970103073A AR013829A1 (es) 1996-07-12 1997-07-10 Un dispositivo medico para suministrar cantidades volumetricas de un primer y un segundo fluido, bioquimicamente reactivos, y metodo para suministrarfibrina a una superficie con dicho dispositivo

Country Status (5)

Country Link
US (1) US6461325B1 (es)
EP (1) EP0917444A1 (es)
AR (1) AR013829A1 (es)
AU (1) AU3720097A (es)
WO (1) WO1998002098A1 (es)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6965014B1 (en) 1996-01-16 2005-11-15 Baxter International Inc. Fibrin material and method for producing and using the same
US6599515B1 (en) 1995-01-16 2003-07-29 Baxter International Inc. Fibrin porous structure
US6613020B1 (en) * 1996-12-06 2003-09-02 Bristol-Myers Squibb Company Method of applying a mixture of two liquid components as well as a device for carrying out the method
US6783514B2 (en) 1997-01-31 2004-08-31 United States Surgical Corporation Fibrin sealant applicator
EP0996474B1 (en) 1997-07-11 2004-10-20 United States Surgical Corporation Fibrin glue applicator system
US6796964B2 (en) * 1997-11-19 2004-09-28 Eidson Associates, Inc Automatic veterinary medicament delivery system
DE69921671T2 (de) * 1998-08-17 2005-10-20 Baxter International Inc., Deerfield Auftragevorrichtung mit variabler abgabe für biologische wirkstoffe die aus mehreren flüssigen komponenten bestehen
US6471670B1 (en) 1998-10-05 2002-10-29 Karl Enrenfels Fibrin sealant applicator system
WO2000072857A1 (en) 1999-06-01 2000-12-07 Bristol-Myers Squibb Company Fibrin polymer structure
FR2796558B1 (fr) * 1999-07-21 2001-10-19 Imedex Biomateriaux Mousse adhesive a usage chirurgical et/ou therapeutique, et procede et kit pour son obtention
ES2242631T3 (es) * 1999-07-21 2005-11-16 Imedex Biomateriaux Espuma de una proteina adhesiva para usos quirurgicos y/o terapeuticos.
ATE425738T1 (de) * 1999-11-17 2009-04-15 Boston Scient Ltd Miniaturisierte vorrichtungen zur abgabe von molekulen in einer tragerflussigkeit
EP1257304B1 (en) * 2000-02-25 2004-02-04 David Sierra Foam-forming wound dressing
AU2002238143B2 (en) 2001-02-27 2006-06-01 Covidien Lp External mixer assembly
DE60121826T2 (de) * 2001-05-09 2007-02-22 Baxter International Inc., Deerfield Fibrinmaterial und verfahren zu seiner herstellung und verwendung
EP1695724B1 (en) * 2001-05-09 2018-01-24 Baxter International Inc. Fibrin material and method for producing and using the same
US6723067B2 (en) * 2001-07-26 2004-04-20 David H. Nielson Apparatus for delivering aerosolized fibrin endoscopically to a wound
US7923431B2 (en) 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
US7544177B2 (en) * 2002-01-24 2009-06-09 The Regents Of The University Of California Aerosol device to deliver bioactive agent
US6863660B2 (en) 2002-03-27 2005-03-08 Hapio Biotech, Inc. Fibrin applicator pistol
US7135027B2 (en) 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
EP1573295A2 (en) 2002-12-11 2005-09-14 Ferrosan A/S Gelatine-based materials as swabs
US7077339B2 (en) * 2003-02-03 2006-07-18 Biomet, Inc. Spray applicator
US20040243044A1 (en) * 2003-06-02 2004-12-02 Penegor Stephen A. Hemostatic wound dressing
EP1713521B1 (en) 2004-01-30 2010-07-28 Ferrosan A/S Haemostatic sprays and compositions
RU2369408C2 (ru) 2004-07-09 2009-10-10 Ферросан А/С Гемостатическая композиция, включающая гиалуроновую кислоту
US8206448B2 (en) 2004-10-29 2012-06-26 Spinal Restoration, Inc. Injection of fibrin sealant using reconstituted components in spinal applications
US20070213660A1 (en) * 2004-10-29 2007-09-13 Mark Richards Fibrin sealant delivery device including pressure monitoring, and method and kits thereof
US7597687B2 (en) 2004-10-29 2009-10-06 Spinal Restoration, Inc. Injection of fibrin sealant including an anesthetic in spinal applications
WO2006029270A1 (en) * 2004-09-07 2006-03-16 Smith & Nephew, Inc. Methods and devices for sterile field transfer
EP1807322B1 (en) 2004-10-12 2008-01-09 S.C.Johnson & Son, Inc Automatic spray device
US8061562B2 (en) 2004-10-12 2011-11-22 S.C. Johnson & Son, Inc. Compact spray device
US7845536B2 (en) 2004-10-18 2010-12-07 Tyco Healthcare Group Lp Annular adhesive structure
US8047407B2 (en) * 2004-10-29 2011-11-01 Spinal Restoration, Inc. Apparatus and method for delivery of biologic sealant
WO2006058153A1 (en) 2004-11-23 2006-06-01 Smith & Nephew, Inc. Composite mixer
CA2593973C (en) * 2005-01-12 2014-11-18 Baxter International Inc. Hand triggered tissue sealant spray apparatus and system
US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US20090038701A1 (en) 2006-01-17 2009-02-12 Baxter International Inc. Device, system and method for mixing
ES2348940T3 (es) * 2006-01-17 2010-12-17 Baxter International Inc. Dispositivo, sistema y método de mezcla.
JP5007056B2 (ja) * 2006-03-13 2012-08-22 テルモ株式会社 塗布具
US7837656B2 (en) * 2006-03-27 2010-11-23 Tyco Healthcare Group Lp Dual air regulated spray applicator
US20080045925A1 (en) * 2006-06-19 2008-02-21 Stepovich Matthew J Drug delivery system
US20080086108A1 (en) * 2006-10-05 2008-04-10 Falkel Michael I Method and apparatus for delivering a drug
US20090005734A1 (en) * 2007-06-27 2009-01-01 Tessaron Medical, Inc. Systems and methods for delivering particles into patient body
EP2259803B2 (en) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US8408480B2 (en) * 2008-04-25 2013-04-02 Confluent Surgical, Inc. Self-cleaning spray tip
US8033483B2 (en) * 2008-04-25 2011-10-11 Confluent Surgical Inc. Silicone spray tip
EP2274039A2 (en) 2008-05-06 2011-01-19 Wilson-Cook Medical Inc. Apparatus and methods for delivering therapeutic agents
JP5255387B2 (ja) * 2008-09-25 2013-08-07 テルモ株式会社 塗布具
US9681860B2 (en) 2008-10-24 2017-06-20 Dennis L Steffen Halo tip spray head atomizer delivery manifold device
US8523805B2 (en) * 2008-10-29 2013-09-03 Biomet Biologics, Llc Method and apparatus for containing, transporting, and providing a material
CA2747390C (en) 2008-12-23 2016-10-04 Wilson-Cook Medical Inc. Apparatus and methods for containing and delivering therapeutic agents
US20100246316A1 (en) * 2009-03-31 2010-09-30 Baxter International Inc. Dispenser, kit and mixing adapter
US8118777B2 (en) 2009-05-29 2012-02-21 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
US9101744B2 (en) 2009-05-29 2015-08-11 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
US20110060361A1 (en) 2009-09-08 2011-03-10 Baxter International Inc. Reconstitution and applicator system for wound sealant product
MY172882A (en) * 2009-10-16 2019-12-13 Alcon Inc Method and device for removing a contact lens from a container
US8641661B2 (en) 2010-01-05 2014-02-04 Baxter International Inc. Mixing system, kit and mixer adapter
CA2726566A1 (en) * 2010-01-11 2011-07-11 Baxter International Inc. Pipette system, pipette tip assembly and kit
JP2013522246A (ja) 2010-03-15 2013-06-13 フェロサン メディカル デバイシーズ エイ/エス 止血および/または創傷治癒を促進するための方法
US8255089B2 (en) 2010-05-28 2012-08-28 S.C. Johnson & Son, Inc. Multiple volatile material dispensing device and operating methodologies therefore
US8672237B2 (en) * 2010-06-25 2014-03-18 Baxter International Inc. Device for mixing and dispensing of two-component reactive surgical sealant
US9125633B2 (en) * 2010-06-25 2015-09-08 Baxter International Inc. Device for mixing and dispensing of two-component reactive surgical sealant
US8678238B2 (en) * 2010-06-30 2014-03-25 Actamax Surgical Materials, Llc Self-contained hand-held yoke-connected device for dispensing a two-part adhesive aerosol
US9211554B2 (en) * 2010-06-30 2015-12-15 Actamax Surgical Materials, Llc Self-contained hand-held direct drive device for dispensing a two-part adhesive aerosol
US20120000935A1 (en) * 2010-06-30 2012-01-05 E. I. Du Pont De Nemours And Company Self-contained hand held yoke-connected device for dispensng a two-part adhesive aerosol
US20120239070A1 (en) * 2011-03-15 2012-09-20 Bandula Wijay Cutting needle for urological and other surgical procedures
US20130068788A1 (en) 2011-09-19 2013-03-21 Thomas P. Gasper Spray Dispenser
EP2763698B1 (en) 2011-10-06 2020-12-02 ImmunoVaccine Technologies Inc. Liposome compositions comprising an adjuvant that activates or increases the activity of tlr2 and uses thereof
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
JP6394916B2 (ja) 2012-06-12 2018-09-26 フェロサン メディカル デバイシーズ エイ/エス 乾燥止血組成物
US9108782B2 (en) 2012-10-15 2015-08-18 S.C. Johnson & Son, Inc. Dispensing systems with improved sensing capabilities
CN104883984A (zh) 2012-11-05 2015-09-02 史密夫和内修公司 用于流体输送的组件和方法
US9867931B2 (en) 2013-10-02 2018-01-16 Cook Medical Technologies Llc Therapeutic agents for delivery using a catheter and pressure source
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
US20140276567A1 (en) * 2013-03-15 2014-09-18 John Goodman Device and System for Dispensing a Biological Sealant
US9724078B2 (en) 2013-06-21 2017-08-08 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US9802166B2 (en) * 2013-08-27 2017-10-31 Gary Hammerlund Vortex mixing system
US9586005B2 (en) 2013-09-30 2017-03-07 Dennis L Steffen Dual syringe delivery device and method of use
CA2928963C (en) 2013-12-11 2020-10-27 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
EP3125774B1 (en) 2014-04-04 2020-05-27 HyperBranch Medical Technology, Inc. Extended tip spray applicator for two-component surgical selant, and methods of use thereof
CA2960309A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
JP6747650B2 (ja) 2014-12-24 2020-08-26 フェロサン メディカル デバイシーズ エイ/エス 第1の物質と第2の物質を保持し混合するためのシリンジ
CN104873231B (zh) * 2015-06-05 2017-11-24 常州药物研究所有限公司 便携式快速止血器
BR112017027695A2 (pt) 2015-07-03 2018-09-04 Ferrosan Medical Devices As seringa para retenção e mistura de primeira e segunda substâncias
US11857994B1 (en) 2015-10-16 2024-01-02 Gary M. Hammerlund Crossover prevention valve
US10639656B1 (en) 2015-10-16 2020-05-05 Gary M. Hammerlund Crossover prevention valve
WO2017083753A1 (en) 2015-11-12 2017-05-18 Herr John C Compositions and methods for vas-occlusive contraception and reversal thereof
US10625032B2 (en) 2016-08-16 2020-04-21 Ethicon, Inc. Spray tips for simultaneous multi-directional delivery of dissimilar fluids
EP3565484B1 (en) 2017-01-05 2024-04-03 Contraline, Inc. Compositions for implanting and reversing stimuli-responsive implants
US10912859B2 (en) 2017-03-08 2021-02-09 Baxter International Inc. Additive able to provide underwater adhesion
US11202848B2 (en) 2017-03-08 2021-12-21 Baxter International Inc. Surgical adhesive able to glue in wet conditions
CN112368028A (zh) 2018-05-09 2021-02-12 弗罗桑医疗设备公司 用于制备止血组合物的方法
US11766383B2 (en) 2018-06-25 2023-09-26 Gary J. Pontecorvo Disposable nasal and eye wash dispenser
US11318040B2 (en) 2018-11-13 2022-05-03 Contraline, Inc. Systems and methods for delivering biomaterials
CN110201268B (zh) * 2019-06-26 2021-08-20 吉林大学 一种便于控制药量的麻醉针
CN110279918B (zh) * 2019-07-23 2021-03-26 河南科技大学第一附属医院 一种用于化疗期间缓解患者口腔黏膜溃疡的口咬式护理器
US11911787B1 (en) 2019-08-16 2024-02-27 Gary Hammerlund Split manifold and method for multiple part fluid applications
US20220241152A1 (en) * 2021-02-02 2022-08-04 Freedom Corp. Fibrin biopolymer formation and application device
KR102385837B1 (ko) * 2022-01-25 2022-04-14 (주)두원메디텍 믹스 스프레이 약액 주입기
KR102385836B1 (ko) * 2022-01-25 2022-04-14 (주)두원메디텍 복강경 수술용 2약액 혼합 분사 장치

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533004A (en) 1943-10-27 1950-12-05 John D Ferry Fibrin clots and methods for preparing the same
US2576006A (en) 1947-11-29 1951-11-20 Research Corp Methods of forming shaped fibrin products
US3523807A (en) 1966-11-25 1970-08-11 Mihaly Gerendas Method of making a cross-linked fibrin prosthesis
US3641240A (en) 1968-09-27 1972-02-08 Wyandotte Chemicals Corp Method for the treatment of an embolus or thrombus
US3723244A (en) 1971-01-18 1973-03-27 Atomic Energy Commission Fibrous fibrin sheet and method for producing same
SE452109B (sv) 1973-01-29 1987-11-16 Pharmacia Ab Rengoringsmedel for vetskande utvertes sarytor
US4537767A (en) 1973-01-29 1985-08-27 Pharmacia Aktiebolag Method for cleansing fluid discharging skin surfaces, wounds and mucous membranes and means for carrying out the method
US4016877A (en) 1976-02-23 1977-04-12 Avicon, Inc. Fibrous collagen derived web having hemostatic and wound sealing properties
US4148664A (en) 1976-05-10 1979-04-10 Avicon, Inc. Preparation of fibrous collagen product having hemostatic and wound sealing properties
US4066083A (en) 1976-06-03 1978-01-03 Pentapharm A.G. Sterile surgical collagen product
US4116898A (en) 1977-01-31 1978-09-26 Becton, Dickinson And Company Non-thrombogenic articles
US4225480A (en) 1977-02-23 1980-09-30 Ppg Industries, Inc. Addition interpolymers having improved stability and two-package compositions comprising such interpolymers and polyepoxides
US4238480A (en) 1978-05-19 1980-12-09 Sawyer Philip Nicholas Method for preparing an improved hemostatic agent and method of employing the same
AT359652B (de) 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
US4675361A (en) 1980-02-29 1987-06-23 Thoratec Laboratories Corp. Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming
AT366916B (de) * 1980-04-02 1982-05-25 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes auf basis von menschlichen oder tierischenproteinen
US4442655A (en) 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
EP0068149A3 (de) 1981-06-25 1983-07-20 Serapharm GmbH & Co. KG Fibrinogen-haltiges Trockenpräparat, dessen Herstellung und Verwendung
SE430218B (sv) 1981-12-30 1983-10-31 Blombaeck E G B Filter och sett att framstella ett sadant
DE3280147D1 (de) 1981-12-30 1990-05-17 New York Blood Center Inc Groessenspezifischer katalysator enthaltend fibrin-gel.
US4578067A (en) 1982-04-12 1986-03-25 Alcon (Puerto Rico) Inc. Hemostatic-adhesive, collagen dressing for severed biological surfaces
JPS58180162A (ja) 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
DE3214337C2 (de) 1982-04-19 1984-04-26 Serapharm - Michael Stroetmann, 4400 Münster Resorbierbares Flachmaterial zum Abdichten und Heilen von Wunden und Verfahren zu dessen Herstellung
DE3234084A1 (de) 1982-09-14 1984-03-15 B. Braun Melsungen Ag, 3508 Melsungen Pharmazeutische zubereitungen zur behandlung von unerwuenschten verwachsungen sowie deren verwendung
DE3248188A1 (de) 1982-12-27 1984-06-28 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung eines kollagen-vlieses
US4548736A (en) 1983-08-29 1985-10-22 Wisconsin Alumni Research Foundation Preparation of protein films
US4600574A (en) 1984-03-21 1986-07-15 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Method of producing a tissue adhesive
US4837285A (en) 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
AT379311B (de) 1984-03-29 1985-12-27 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
EP0166263A1 (en) 1984-05-31 1986-01-02 Green Cross Corporation Filler composition for filling in defect or hollow portion of bone and kit or set for the preparation of the filler composition
US4600533A (en) 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
US5223420A (en) 1985-03-01 1993-06-29 Institut National De La Sante Et De La Recherche Medicale Elastin-based product, a procedure for its preparation and its biological applications; in particular as biomaterials and artificial supports
WO1986007541A1 (en) 1985-06-19 1986-12-31 Yasushi Zyo Composition which can impart antithrombotic ability and medical apparatus to be in contact with blood
US4690684A (en) 1985-07-12 1987-09-01 C. R. Bard, Inc. Meltable stent for anastomosis
JPS6229532A (ja) 1985-07-31 1987-02-07 Koken:Kk 抗血栓性医用材料及びその製造方法
US5002551A (en) 1985-08-22 1991-03-26 Johnson & Johnson Medical, Inc. Method and material for prevention of surgical adhesions
US5049393A (en) 1986-01-07 1991-09-17 Baylor College Of Medicine Anti-thrombogenic elastomer and objects and prostheses made therefrom
US4720512A (en) 1986-03-24 1988-01-19 Becton, Dickinson And Company Polymeric articles having enhanced antithrombogenic activity
US4786556A (en) 1986-03-24 1988-11-22 Becton, Dickinson And Company Polymeric articles having enhanced antithrombogenic activity
US4760131A (en) 1986-04-23 1988-07-26 Collagen Corporation Wound-healing composition
US4840626A (en) 1986-09-29 1989-06-20 Johnson & Johnson Patient Care, Inc. Heparin-containing adhesion prevention barrier and process
DE3722904A1 (de) 1987-01-09 1988-07-21 Harald Maslanka Injektionseinrichtung mit doppelkanuele fuer ein endoskop
US5080893A (en) 1988-05-31 1992-01-14 University Of Florida Method for preventing surgical adhesions using a dilute solution of polymer
US5244799A (en) 1987-05-20 1993-09-14 Anderson David M Preparation of a polymeric hydrogel containing micropores and macropores for use as a cell culture substrate
US4882148A (en) 1987-06-18 1989-11-21 Corvita Corporation Crack prevention and improved thrombogenicity of implanted prostheses by sulfonation
EP0299698B1 (en) 1987-07-14 1992-09-09 Sankyo Company Limited Composition for forming antithrombotic medical appliances
US5260420A (en) 1987-07-30 1993-11-09 Centre Regional De Transfusion Sanguine De Lille Concentrate of thrombin coagulable proteins, the method of obtaining same and therapeutical use thereof
US4978336A (en) 1987-09-29 1990-12-18 Hemaedics, Inc. Biological syringe system
US5364622A (en) 1987-12-04 1994-11-15 Dr. Karl Thomae Gmbh Methods for preventing adhesions to organs and parts of organs by application of tissue plasminogen activator and hydroxyethylcellulose hydrogel
US5201745A (en) 1988-03-15 1993-04-13 Imedex Visceral surgery patch
AT397203B (de) 1988-05-31 1994-02-25 Immuno Ag Gewebeklebstoff
US5140016A (en) 1988-05-31 1992-08-18 University Of Florida Method and composition for preventing surgical adhesions using a dilute solution of polymer
US5182317A (en) 1988-06-08 1993-01-26 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US4874368A (en) 1988-07-25 1989-10-17 Micromedics, Inc. Fibrin glue delivery system
US4948540A (en) 1988-08-01 1990-08-14 Semex Medical, Inc. Method of preparing collagen dressing sheet material
US5126140A (en) 1988-08-03 1992-06-30 New England Deaconess Hospital Corporation Thrombomodulin-coated bicompatible substance
US5019393A (en) 1988-08-03 1991-05-28 New England Deaconess Hospital Corporation Biocompatible substance with thromboresistance
US5167960A (en) 1988-08-03 1992-12-01 New England Deaconess Hospital Corporation Hirudin-coated biocompatible substance
US5112615A (en) 1988-08-03 1992-05-12 New England Deaconess Hospital Corporation Soluble hirudin conjugates
US5213580A (en) 1988-08-24 1993-05-25 Endoluminal Therapeutics, Inc. Biodegradable polymeric endoluminal sealing process
US5053048A (en) 1988-09-22 1991-10-01 Cordis Corporation Thromboresistant coating
US4911926A (en) 1988-11-16 1990-03-27 Mediventures Inc. Method and composition for reducing postsurgical adhesions
CA2004740A1 (en) 1988-12-07 1990-06-07 Cary Linsky Low molecular weight heparin, heparinoid and hexuronyl hexosaminoglycan sulfate containing adhesion prevention barrier and process
DE3841397A1 (de) 1988-12-08 1990-06-21 Melzer Wolfgang Poroeser resorbierbarer arzneistofftraeger
DE69004098T2 (de) * 1989-08-10 1994-08-04 Gore & Ass Medizinisches spendesystem für gewebeklebstoffkomponenten.
US5116315A (en) * 1989-10-03 1992-05-26 Hemaedics, Inc. Biological syringe system
US5071664A (en) 1989-10-20 1991-12-10 Brown Sand T Method of removing sulfites from standard wine
US5525348A (en) 1989-11-02 1996-06-11 Sts Biopolymers, Inc. Coating compositions comprising pharmaceutical agents
WO1991017724A1 (en) 1990-05-17 1991-11-28 Harbor Medical Devices, Inc. Medical device polymer
US5455040A (en) 1990-07-26 1995-10-03 Case Western Reserve University Anticoagulant plasma polymer-modified substrate
US5292362A (en) 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5209776A (en) 1990-07-27 1993-05-11 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5173295A (en) 1990-10-05 1992-12-22 Advance Biofactures Of Curacao, N.V. Method of enhancing the regeneration of injured nerves and adhesive pharamaceutical formulation therefor
US5486357A (en) 1990-11-08 1996-01-23 Cordis Corporation Radiofrequency plasma biocompatibility treatment of inside surfaces
JPH05192387A (ja) 1990-11-08 1993-08-03 Matrix Pharmaceut Inc 生物医学的用途のための線維素/コラーゲン膜
EP0495478B1 (en) 1991-01-16 1999-04-21 Toyo Boseki Kabushiki Kaisha A material compatible with blood
US5156613A (en) 1991-02-13 1992-10-20 Interface Biomedical Laboratories Corp. Collagen welding rod material for use in tissue welding
CA2109960C (en) 1991-05-31 2000-07-18 Li-Chien Hsu Thromboresistant coating for defoaming applications
JPH06500802A (ja) 1991-06-14 1994-01-27 アムジエン・インコーポレーテツド コラーゲンフィルムによるタンパクのドラッグ・デリバリー
FR2679778B1 (fr) 1991-08-02 1995-07-07 Coletica Utilisation de collagene reticule par un agent de reticulation pour la fabrication d'une membrane suturable, biocompatible, a resorption lente, ainsi qu'une telle membrane.
EP0534178B1 (en) 1991-09-27 2001-04-18 Omrix Biopharmaceuticals S.A. Improved tissue glue prepared by using cryoprecipitate
US5368563A (en) * 1991-12-18 1994-11-29 Micromedics, Inc. Sprayer assembly for physiologic glue
US5376376A (en) 1992-01-13 1994-12-27 Li; Shu-Tung Resorbable vascular wound dressings
GB9206509D0 (en) 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
US5272074A (en) 1992-04-23 1993-12-21 Mcmaster University Fibrin coated polymer surfaces
US5376692A (en) 1992-05-15 1994-12-27 Purdue Research Foundation Method of binding using irradiation and product with albumin bound to biomaterials
FR2692582B1 (fr) 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
CA2124320C (en) * 1992-09-26 2007-02-06 Nobuto Fukunaga Applicator for applying a biocompatible adhesive
CN1091315A (zh) 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
US5278200A (en) 1992-10-30 1994-01-11 Medtronic, Inc. Thromboresistant material and articles
US5397816A (en) 1992-11-17 1995-03-14 Ethicon, Inc. Reinforced absorbable polymers
DE4304716A1 (de) 1993-02-16 1994-08-18 Melzer Wolfgang Lokal applizierbares Arzneimittel mit verzögerter Freisetzung
US5395923A (en) 1993-02-23 1995-03-07 Haemacure-Biotech, Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
AT400675B (de) * 1993-10-18 1996-02-26 Immuno Ag Spritzengarnitur zur aufbewahrung und applikation eines mehrkomponentenmaterials, spritzenvorrichtung und betätigungseinrichtung hiefür sowie verfahren zum herstellen einer befüllten, sterilen spritzenvorrichtung
AT400304B (de) * 1994-02-28 1995-12-27 Immuno Ag Vorrichtung zur applikation eines mehrkomponenten-gewebeklebstoffes
US5578073A (en) 1994-09-16 1996-11-26 Ramot Of Tel Aviv University Thromboresistant surface treatment for biomaterials
US5605541A (en) * 1994-12-07 1997-02-25 E. R. Squibb And Sons, Inc. Fibrin sealant applicatoor
ATE244584T1 (de) * 1995-01-16 2003-07-15 Baxter Int Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
US5580923A (en) 1995-03-14 1996-12-03 Collagen Corporation Anti-adhesion films and compositions for medical use
CA2222426A1 (en) * 1995-06-06 1996-12-12 Andrew G. Hood, Iii Wound sealant preparation and application device and method
US5697903A (en) * 1996-02-22 1997-12-16 Ultradent Products, Inc. Methods and apparatus for dispensing compositions

Also Published As

Publication number Publication date
EP0917444A1 (en) 1999-05-26
WO1998002098A1 (en) 1998-01-22
US6461325B1 (en) 2002-10-08
AU3720097A (en) 1998-02-09

Similar Documents

Publication Publication Date Title
AR013829A1 (es) Un dispositivo medico para suministrar cantidades volumetricas de un primer y un segundo fluido, bioquimicamente reactivos, y metodo para suministrarfibrina a una superficie con dicho dispositivo
ATE244584T1 (de) Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
CO4700316A1 (es) Boquilla para el uso con espumas para combatir el fuego
CU22987A3 (es) Dispositivo para distribuir un líquido bajo presión y método para despachar el mismo
AR016960A1 (es) Bomba de dispensado operable manualmente, y recipiente secundario para contener un contenido seleccionado
AR009250A1 (es) Un dispositivo de suministro
ES2137013T3 (es) Aparato para mezclar un fluido y un liquido.
DE69912625D1 (de) Zahnbürste mit flüssigkeitabgabesystem
ATE21633T1 (de) Druckbehaelter mit abgabepumpe.
AR007303A1 (es) Dispensador para fluidos
CO5390100A1 (es) Empaque dual de dispensado de liquidos
EP0473892A3 (en) Dispenser for aseptic fluid
CU23012A3 (es) Montaje de válvula para un recipiente de bebidas, montaje de válvula para un recipiente de bebidas, un recipiente para la bebida y un método para llenun recipiente para la bebida y un método para llenar y vaciar el recipiente de bebidas ar y vaciar el recipiente de bebidas
PL292817A1 (en) Suction and/or discharge valve for metering and atomizing pumps suitable for both low viscosity liquids and pasty materials
ES2081791T1 (es) Dispensador de jabon del tipo accionable por presion.
ATE358052T1 (de) Flüssigkeitsspender mit verbessertem abgabesystem für reinigungslösungsmittel
ES2122369T3 (es) Unidad distribuidora de material en polvo.
DK0725719T3 (da) Fremgangsmåde til indføring af et flydende medium i en hulhed
ES2114174T3 (es) Dispositivo para la dispensacion gota a gota de un fluido contenido en un recipiente flexible.
BR9006922A (pt) Sistema dosador e processo para ministrar uma dose medida de fluido
CO4980908A1 (es) Sistema de dispensado de utilizacion dual
DE3580934D1 (de) Ausgabebehaelter fuer fluessigkeiten.
DE69804241D1 (de) Flüssigkeitsabgabesystem
EA199800939A1 (ru) Наполняющее устройство
DE69919854D1 (de) Ausgabevorrichtung