DK1871237T3 - Håndaktiverret vævsforseglingssprayapparatur og -system - Google Patents

Håndaktiverret vævsforseglingssprayapparatur og -system

Info

Publication number
DK1871237T3
DK1871237T3 DK06718085.1T DK06718085T DK1871237T3 DK 1871237 T3 DK1871237 T3 DK 1871237T3 DK 06718085 T DK06718085 T DK 06718085T DK 1871237 T3 DK1871237 T3 DK 1871237T3
Authority
DK
Denmark
Prior art keywords
spray apparatus
tissue sealing
activated tissue
hand activated
sealing spray
Prior art date
Application number
DK06718085.1T
Other languages
English (en)
Inventor
Heinz Redl
Zafar Khakpour
Scott R Ariagno
Andreas Kellner
Lillian G Zakarija
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Application granted granted Critical
Publication of DK1871237T3 publication Critical patent/DK1871237T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0408—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing two or more liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00491—Surgical glue applicators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0416—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid
    • B05B7/0483—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with gas and liquid jets intersecting in the mixing chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
    • B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
    • B05C17/00503—Details of the outlet element
    • B05C17/00516—Shape or geometry of the outlet orifice or the outlet element
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
    • B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
    • B05C17/00553—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes with means allowing the stock of material to consist of at least two different components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
    • B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
    • B05C17/015—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes with pneumatically or hydraulically actuated piston or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00491—Surgical glue applicators
    • A61B2017/00495—Surgical glue applicators for two-component glue

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Geometry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgical Instruments (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Nozzles (AREA)
  • Coating Apparatus (AREA)
  • Prostheses (AREA)
DK06718085.1T 2005-01-12 2006-01-12 Håndaktiverret vævsforseglingssprayapparatur og -system DK1871237T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64336805P 2005-01-12 2005-01-12
PCT/US2006/000970 WO2006076427A2 (en) 2005-01-12 2006-01-12 Hand triggered tissue sealant spray apparatus and system

Publications (1)

Publication Number Publication Date
DK1871237T3 true DK1871237T3 (da) 2013-02-04

Family

ID=36218163

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06718085.1T DK1871237T3 (da) 2005-01-12 2006-01-12 Håndaktiverret vævsforseglingssprayapparatur og -system

Country Status (17)

Country Link
US (3) US7537174B2 (da)
EP (2) EP2514369A1 (da)
JP (1) JP4873749B2 (da)
KR (1) KR101225359B1 (da)
CN (1) CN101102722B (da)
AU (1) AU2006205001B2 (da)
BR (1) BRPI0606642B8 (da)
CA (1) CA2593973C (da)
DK (1) DK1871237T3 (da)
ES (1) ES2398229T3 (da)
HR (1) HRP20070311B1 (da)
MX (1) MX2007008374A (da)
PL (1) PL1871237T3 (da)
PT (1) PT1871237E (da)
RU (1) RU2397714C2 (da)
WO (1) WO2006076427A2 (da)
ZA (1) ZA200705689B (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1871237T3 (pl) * 2005-01-12 2013-05-31 Baxter Int Ręcznie wyzwalany aparat rozpraszający klej tkankowy oraz układ
WO2007084919A1 (en) * 2006-01-17 2007-07-26 Baxter International Inc. Device, system and method for mixing
US20090038701A1 (en) 2006-01-17 2009-02-12 Baxter International Inc. Device, system and method for mixing
BRPI0708152A2 (pt) * 2006-02-24 2011-05-17 Sulzer Mixpac Ag dispositivo de administração para uma seringa dupla
JP5007056B2 (ja) * 2006-03-13 2012-08-22 テルモ株式会社 塗布具
ES2335709T3 (es) * 2006-05-17 2010-03-31 Medmix Systems Ag Dispositivo dispensador con un conjunto de pulverizacion.
US9622731B2 (en) * 2008-01-28 2017-04-18 Baxter International Inc. Sealant applicator with malleable section
US9179898B2 (en) 2008-12-30 2015-11-10 Baxter International Inc. Tissue sealing system and apparatus
WO2010081244A1 (de) 2009-01-13 2010-07-22 Medmix Systems Ag Austragvorrichtung mit druckgasunterstützung
BRPI1008909B8 (pt) * 2009-02-20 2021-06-22 Covidien Lp sistema para tratar uma veia
US20100246316A1 (en) * 2009-03-31 2010-09-30 Baxter International Inc. Dispenser, kit and mixing adapter
ES2332032B1 (es) * 2009-06-09 2010-06-07 Grifols, S.A. Dispositivo de aplicacion de adhesivo de fibrina.
EP3284494A1 (en) 2009-07-30 2018-02-21 Tandem Diabetes Care, Inc. Portable infusion pump system
WO2011031783A1 (en) 2009-09-08 2011-03-17 Baxter International Inc. Reconstitution and applicator system for wound sealant product
JP5557275B2 (ja) * 2009-11-10 2014-07-23 株式会社 モデルクリエイト 二液型反応液の同時吐出装置
US8641661B2 (en) 2010-01-05 2014-02-04 Baxter International Inc. Mixing system, kit and mixer adapter
CA2726566A1 (en) * 2010-01-11 2011-07-11 Baxter International Inc. Pipette system, pipette tip assembly and kit
CA2790050C (en) * 2010-03-23 2021-04-20 Hyperbranch Medical Technology, Inc. Disposable syringe applicators for multi-component formulations, and methods of use thereof
JP2013523336A (ja) * 2010-04-05 2013-06-17 ネオメンド、インク． 創傷シーラントを適用する方法および装置
USD726304S1 (en) * 2012-03-22 2015-04-07 Terumo Kabushiki Kaisha Medicament sprayer
US8973847B2 (en) * 2012-07-09 2015-03-10 Easy Spray Llc Non-aerosol liquid spray device with continuous spray
DE102013103552A1 (de) * 2013-04-09 2014-10-09 Ivoclar Vivadent Ag Spritze
US10085729B2 (en) * 2014-03-06 2018-10-02 Ethicon, Inc. Methods and devices for forming biomedical coatings using variable mixing ratios of multi-part compositions
US10952709B2 (en) 2014-04-04 2021-03-23 Hyperbranch Medical Technology, Inc. Extended tip spray applicator for two-component surgical sealant, and methods of use thereof
CN104324440A (zh) * 2014-07-30 2015-02-04 杭州普济医药技术开发有限公司 一种猪纤维蛋白粘合剂雾化给药装置
DE102015101126A1 (de) * 2015-01-27 2016-07-28 Heraeus Medical Gmbh Pasten-Applikationsvorrichtung zum Mischen einer Paste aus zwei Komponenten
CH711347A1 (de) * 2015-07-22 2017-01-31 Medmix Systems Ag Austragvorrichtung für zwei Spritzen.
US9572555B1 (en) * 2015-09-24 2017-02-21 Ethicon, Inc. Spray or drip tips having multiple outlet channels
CN106075712A (zh) * 2016-07-25 2016-11-09 江西高大生物医疗科技有限公司 一种医用双液体均匀混合喷雾器
US10625032B2 (en) * 2016-08-16 2020-04-21 Ethicon, Inc. Spray tips for simultaneous multi-directional delivery of dissimilar fluids
KR102559800B1 (ko) * 2017-04-19 2023-07-26 백스터 인터내셔널 인코포레이티드 비-폐색 분배 장치
CN107975217A (zh) * 2017-12-22 2018-05-01 中建八局第建设有限公司 一种能够自动泄压的充电式填缝枪
US11596741B2 (en) * 2018-04-19 2023-03-07 Ethicon, Inc. Adapter manifold for multi-barrel syringe applicator
US11517527B2 (en) 2018-11-05 2022-12-06 Ethicon, Inc. Systems, devices and methods for making and expressing foam used in medical procedures
US12349882B2 (en) * 2018-11-07 2025-07-08 Baxter International Inc. Dual check valve one handed applicator
CN111203363B (zh) 2018-11-22 2023-02-21 伊利诺斯工具制品有限公司 喷嘴
US20210299688A1 (en) * 2020-03-31 2021-09-30 Easy Spray Llc Recyclable vacuum-driven dispenser
WO2025101187A1 (en) * 2023-11-08 2025-05-15 Bard Peripheral Vascular, Inc. Multi-component sealant delivery systems having two free-standing barrels

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB962163A (en) * 1959-09-04 1964-07-01 British United Shoe Machinery Improvements in or relating to apparatus for handling cement
DE3725552A1 (de) 1987-08-01 1989-02-09 Hoechst Ag Spruehkopf zum applizieren eines mehrkomponentenmaterials mittels gas
SU1666571A1 (ru) * 1988-11-15 1991-07-30 Куйбышевский авиационный институт им.акад.С.П.Королева Порошковый материал дл напылени защитных покрытий и способ его получени
US5582596A (en) * 1992-09-26 1996-12-10 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Applicator for applying a biocompatible adhesive
AT400304B (de) * 1994-02-28 1995-12-27 Immuno Ag Vorrichtung zur applikation eines mehrkomponenten-gewebeklebstoffes
WO1995031138A1 (de) * 1994-05-12 1995-11-23 Omrix Biopharmaceuticals S.A. Manuell betätigbare vorrichtung zum ausgeben eines fluids
US5419491A (en) * 1994-05-23 1995-05-30 Mattson Spray Equipment, Inc. Two component fluid spray gun and method
US5605541A (en) 1994-12-07 1997-02-25 E. R. Squibb And Sons, Inc. Fibrin sealant applicatoor
WO1996039212A2 (en) * 1995-06-06 1996-12-12 Quantic Biomedical Partners Wound sealant preparation and application device and method
WO1997020585A1 (en) * 1995-12-07 1997-06-12 Bristol-Myers Squibb Company A method of applying a mixture of two liquid components
US5759169A (en) 1996-03-13 1998-06-02 New York Blood Center Inc. Fibrin sealant glue-gun
TR199802314T2 (xx) * 1996-05-13 1999-03-22 B. Braun Medical, Inc. B�k�lgen, �ok-b�lmeli ila� kab� ve bu kab�n yap�m ve kullan�m y�ntemi.
US5944709A (en) * 1996-05-13 1999-08-31 B. Braun Medical, Inc. Flexible, multiple-compartment drug container and method of making and using same
AR013829A1 (es) * 1996-07-12 2001-01-31 Baxter Int Un dispositivo medico para suministrar cantidades volumetricas de un primer y un segundo fluido, bioquimicamente reactivos, y metodo para suministrarfibrina a una superficie con dicho dispositivo
US5759171A (en) 1996-09-27 1998-06-02 Thermogenesis Corp. Sprayer for fibrin glue
IL129916A0 (en) * 1996-11-15 2000-02-29 Bristol Myers Squibb Co Devices and method for applying a mixture of two or more liquid components to form a biomaterial
US6613020B1 (en) 1996-12-06 2003-09-02 Bristol-Myers Squibb Company Method of applying a mixture of two liquid components as well as a device for carrying out the method
DE19709896C1 (de) * 1997-03-11 1998-12-24 Omrix Biopharm Sa Applikator zum Auftragen eines Ein- oder Mehrkomponenten-Fluids und Verfahren zum Aufsprühen eines derartigen Fluids
US5971956A (en) 1997-04-15 1999-10-26 Biosurgical Corporation Medical suctioning apparatus and methods of use
ATE495786T1 (de) * 1997-04-14 2011-02-15 Baxter Int Austragevorrichtung für flüssigkeiten welches abgemessene mengen unter anwendung eines kontrollierten soges abgibt
US6331172B1 (en) * 1997-04-14 2001-12-18 Baxter International Inc. Applicator for dispensing measured quantities with use of controlled suction
US6770050B2 (en) 1997-04-14 2004-08-03 Baxter International Inc. Multipurpose fluid applicator and method, with surgical uses
US6733472B1 (en) 1997-04-14 2004-05-11 Baxter International Inc. Sealant applicator tip and application method
US6884230B1 (en) 1998-03-09 2005-04-26 Baxter International Inc. Dispensing head for a tissue sealant applicator and process of use
US6047861A (en) 1998-04-15 2000-04-11 Vir Engineering, Inc. Two component fluid dispenser
US6461361B1 (en) * 1998-05-01 2002-10-08 Baxter International Inc. Gas-driven spraying of mixed sealant agents
EP1076517A4 (en) 1998-05-06 2003-01-15 Bristol Myers Squibb Co DIRECTIONAL ENDOSCOPIC TRANSPORT OF MATERIAL
WO2000015117A1 (en) 1998-09-17 2000-03-23 Focal, Inc. Self-cleaning fluid delivery device for medical applications
DE19910972C1 (de) * 1999-03-09 2000-10-26 Omrix Biopharm Sa Vorrichtung zum Auftragen eines fließfähigen Mediums, insbesondere eines Gewebeklebstoffs
US6432084B1 (en) 1999-05-07 2002-08-13 Baxter International Inc. Non-newtonian fluid spray applicator and method
CA2316554C (en) * 1999-08-25 2007-10-23 Bristol-Myers Squibb Company Applicator and electro-mechanical applicator drive system
RU2195897C2 (ru) * 2000-03-03 2003-01-10 Новиков Николай Николаевич Устройство для нанесения антисептического покрытия на поверхность медицинских изделий
US6585696B2 (en) 2000-12-22 2003-07-01 Baxter International, Inc. Method and apparatus for applying a medically useful multiple component material
GB2374014A (en) 2001-04-02 2002-10-09 Cambridge Consultants Biological sealant storage and dispensing system
CA2371466C (en) * 2002-02-12 2010-02-09 Medical International Technology (Mit) Inc. Needleless injector
US6852099B2 (en) 2002-06-04 2005-02-08 Baxter International Inc. Device for controllably applying liquids to body surfaces
PL1871237T3 (pl) * 2005-01-12 2013-05-31 Baxter Int Ręcznie wyzwalany aparat rozpraszający klej tkankowy oraz układ

Also Published As

Publication number Publication date
AU2006205001A1 (en) 2006-07-20
US20110172703A1 (en) 2011-07-14
US7909267B2 (en) 2011-03-22
EP2514369A1 (en) 2012-10-24
US20060191962A1 (en) 2006-08-31
CA2593973C (en) 2014-11-18
PL1871237T3 (pl) 2013-05-31
RU2397714C2 (ru) 2010-08-27
ES2398229T3 (es) 2013-03-14
CN101102722B (zh) 2010-12-15
HRP20070311B1 (hr) 2016-01-01
JP4873749B2 (ja) 2012-02-08
KR101225359B1 (ko) 2013-01-22
RU2007130712A (ru) 2009-02-20
JP2008526436A (ja) 2008-07-24
MX2007008374A (es) 2007-11-21
AU2006205001B2 (en) 2011-05-26
BRPI0606642A2 (pt) 2009-07-14
EP1871237B1 (en) 2012-10-24
WO2006076427A2 (en) 2006-07-20
CN101102722A (zh) 2008-01-09
ZA200705689B (en) 2008-12-31
BRPI0606642B1 (pt) 2018-08-21
EP1871237A2 (en) 2008-01-02
WO2006076427A3 (en) 2006-09-28
BRPI0606642B8 (pt) 2021-06-22
US20090152305A1 (en) 2009-06-18
US8469289B2 (en) 2013-06-25
KR20070100286A (ko) 2007-10-10
HRP20070311A2 (en) 2007-09-30
PT1871237E (pt) 2012-12-24
US7537174B2 (en) 2009-05-26
CA2593973A1 (en) 2006-07-20

Similar Documents

Publication Publication Date Title
DK1871237T3 (da) Håndaktiverret vævsforseglingssprayapparatur og -system
EP1871245A4 (en) FABRIC DILATION SYSTEMS AND RELATED METHODS
EP1909674A4 (en) INSTRUMENT AND METHODS FOR ELECTROSURGERY
DE602007002740D1 (de) Trokar und Behandlungssystem
EP1854415A4 (en) SURGICAL TREATMENT DEVICE
IL187444A0 (en) Tissue treatment device and method
IL239695A0 (en) Tissue protective peptides and their uses
ZA200802437B (en) Apparatus with actives from tissue
ZA200802398B (en) Apparatus with actives from tissue
EP1848353A4 (en) ORTHOPEDIC PLATE SYSTEM AND METHOD OF USE
DE602006021274D1 (de) Ultraschallvorrichtung und ultraschallverfahren
DE602005027052D1 (de) Endoskopbehandlungssystem
ATE467582T1 (de) Sprühvorrichtung
PL2256063T3 (pl) Urządzenie rozpylające oraz sposób użycia urządzenia rozpylającego
BRPI0906047A2 (pt) "método e aparelho de tratamento de ar e sanitizalão"
GB0503380D0 (en) Tissue treatment system
ATE474796T1 (de) Sprühvorrichtung
ATE467581T1 (de) Sprühvorrichtung
EP1967123A4 (en) ENDOSCOPE AND ENDOSCOPE SYSTEM
DK1863899T3 (da) Hudbehandlingspræparater
SE0700997L (sv) Fastsättningsapparat och -system
GB0507460D0 (en) Fluid disinfection apparatus and system
GB2428987B (en) Spray Device
DE602006003063D1 (de) Tripeptid- und tetrapeptidsulfone
GB0516069D0 (en) Pharmaceutical and use thereof