JPS59152378A - ニザチジン合成法 - Google Patents
ニザチジン合成法Info
- Publication number
- JPS59152378A JPS59152378A JP59021529A JP2152984A JPS59152378A JP S59152378 A JPS59152378 A JP S59152378A JP 59021529 A JP59021529 A JP 59021529A JP 2152984 A JP2152984 A JP 2152984A JP S59152378 A JPS59152378 A JP S59152378A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- methyl
- product
- reaction
- isothiourea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Credit Cards Or The Like (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46429683A | 1983-02-07 | 1983-02-07 | |
| US464296 | 1983-02-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59152378A true JPS59152378A (ja) | 1984-08-31 |
| JPH0576473B2 JPH0576473B2 (en, 2012) | 1993-10-22 |
Family
ID=23843341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59021529A Granted JPS59152378A (ja) | 1983-02-07 | 1984-02-07 | ニザチジン合成法 |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0116452B1 (en, 2012) |
| JP (1) | JPS59152378A (en, 2012) |
| KR (1) | KR860000767B1 (en, 2012) |
| AT (1) | ATE84530T1 (en, 2012) |
| AU (1) | AU559639B2 (en, 2012) |
| BG (1) | BG45216A3 (en, 2012) |
| CA (1) | CA1221369A (en, 2012) |
| CS (1) | CS240994B2 (en, 2012) |
| DD (1) | DD216459A5 (en, 2012) |
| DE (1) | DE3486032T2 (en, 2012) |
| DK (2) | DK164501C (en, 2012) |
| EG (1) | EG17702A (en, 2012) |
| ES (1) | ES529492A0 (en, 2012) |
| FI (1) | FI840474L (en, 2012) |
| GB (1) | GB2134521B (en, 2012) |
| GR (1) | GR81755B (en, 2012) |
| HU (2) | HU194198B (en, 2012) |
| IE (1) | IE56763B1 (en, 2012) |
| IL (1) | IL70880A (en, 2012) |
| NZ (1) | NZ207046A (en, 2012) |
| PH (1) | PH19941A (en, 2012) |
| PL (1) | PL138793B1 (en, 2012) |
| PT (1) | PT78063A (en, 2012) |
| RO (1) | RO87706A (en, 2012) |
| SU (1) | SU1303028A3 (en, 2012) |
| UA (1) | UA6020A1 (en, 2012) |
| ZA (1) | ZA84869B (en, 2012) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1277325C (en) * | 1985-12-18 | 1990-12-04 | Bruce A. Slomski | Synthesis of nizatidine |
| ES2038922B1 (es) * | 1991-12-30 | 1994-04-16 | Fermentaciones Y Sintesis Espa | Procedimiento para la obtencion de nizatidina. |
| US5470865A (en) * | 1994-08-30 | 1995-11-28 | Eli Lilly And Company | Pharmaceutical composition |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5583768A (en) * | 1978-12-18 | 1980-06-24 | Bristol Myers Co | Organic compound |
| JPS5791980A (en) * | 1980-10-02 | 1982-06-08 | Lilly Co Eli | 2,4-disubstituted thiazole derivatives |
-
1984
- 1984-02-06 SU SU843700902A patent/SU1303028A3/ru active
- 1984-02-06 DK DK051984A patent/DK164501C/da not_active IP Right Cessation
- 1984-02-06 CS CS84812A patent/CS240994B2/cs unknown
- 1984-02-06 ZA ZA84869A patent/ZA84869B/xx unknown
- 1984-02-06 RO RO84113523A patent/RO87706A/ro unknown
- 1984-02-06 GB GB08403109A patent/GB2134521B/en not_active Expired
- 1984-02-06 UA UA3700902A patent/UA6020A1/uk unknown
- 1984-02-06 HU HU86873A patent/HU194198B/hu unknown
- 1984-02-06 IL IL70880A patent/IL70880A/xx not_active IP Right Cessation
- 1984-02-06 EP EP84300720A patent/EP0116452B1/en not_active Expired - Lifetime
- 1984-02-06 DD DD84259880A patent/DD216459A5/de unknown
- 1984-02-06 DE DE8484300720T patent/DE3486032T2/de not_active Expired - Lifetime
- 1984-02-06 CA CA000446798A patent/CA1221369A/en not_active Expired
- 1984-02-06 PH PH30202A patent/PH19941A/en unknown
- 1984-02-06 FI FI840474A patent/FI840474L/fi not_active Application Discontinuation
- 1984-02-06 HU HU84477A patent/HU190527B/hu not_active IP Right Cessation
- 1984-02-06 AU AU24215/84A patent/AU559639B2/en not_active Ceased
- 1984-02-06 GR GR73715A patent/GR81755B/el unknown
- 1984-02-06 BG BG064154A patent/BG45216A3/xx unknown
- 1984-02-06 PT PT78063A patent/PT78063A/pt not_active IP Right Cessation
- 1984-02-06 AT AT84300720T patent/ATE84530T1/de not_active IP Right Cessation
- 1984-02-06 ES ES529492A patent/ES529492A0/es active Granted
- 1984-02-06 IE IE274/84A patent/IE56763B1/en not_active IP Right Cessation
- 1984-02-07 KR KR1019840000567A patent/KR860000767B1/ko not_active Expired
- 1984-02-07 EG EG92/84A patent/EG17702A/xx active
- 1984-02-07 JP JP59021529A patent/JPS59152378A/ja active Granted
- 1984-02-07 NZ NZ207046A patent/NZ207046A/en unknown
- 1984-02-07 PL PL1984246097A patent/PL138793B1/pl unknown
-
1992
- 1992-02-19 DK DK021292A patent/DK164906C/da not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5583768A (en) * | 1978-12-18 | 1980-06-24 | Bristol Myers Co | Organic compound |
| JPS5791980A (en) * | 1980-10-02 | 1982-06-08 | Lilly Co Eli | 2,4-disubstituted thiazole derivatives |
Also Published As
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