JPS52136172A - Polypeptide* its preparation and medical and veterinary compositions having rulibeline synergistic effect - Google Patents

Polypeptide* its preparation and medical and veterinary compositions having rulibeline synergistic effect

Info

Publication number
JPS52136172A
JPS52136172A JP5418677A JP5418677A JPS52136172A JP S52136172 A JPS52136172 A JP S52136172A JP 5418677 A JP5418677 A JP 5418677A JP 5418677 A JP5418677 A JP 5418677A JP S52136172 A JPS52136172 A JP S52136172A
Authority
JP
Japan
Prior art keywords
rulibeline
polypeptide
medical
preparation
synergistic effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5418677A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6113480B2 (enExample
Inventor
Suwaruupu Doutsuta Anando
Jiyon Arubaato Fuaa Baarinton
Buraian Jiyairuzu Maikuru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of JPS52136172A publication Critical patent/JPS52136172A/ja
Publication of JPS6113480B2 publication Critical patent/JPS6113480B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Plant Substances (AREA)
JP5418677A 1976-05-11 1977-05-11 Polypeptide* its preparation and medical and veterinary compositions having rulibeline synergistic effect Granted JPS52136172A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19327/76A GB1524747A (en) 1976-05-11 1976-05-11 Polypeptide

Publications (2)

Publication Number Publication Date
JPS52136172A true JPS52136172A (en) 1977-11-14
JPS6113480B2 JPS6113480B2 (enExample) 1986-04-14

Family

ID=10127509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5418677A Granted JPS52136172A (en) 1976-05-11 1977-05-11 Polypeptide* its preparation and medical and veterinary compositions having rulibeline synergistic effect

Country Status (27)

Country Link
US (1) US4100274A (enExample)
JP (1) JPS52136172A (enExample)
AT (2) AT379400B (enExample)
AU (1) AU508025B2 (enExample)
BE (1) BE854467A (enExample)
BG (1) BG60740B2 (enExample)
CA (1) CA1101844A (enExample)
CH (2) CH627151A5 (enExample)
CS (1) CS199673B2 (enExample)
DD (1) DD136738A5 (enExample)
DE (1) DE2720245C2 (enExample)
DK (1) DK149596C (enExample)
ES (1) ES458691A1 (enExample)
FI (1) FI64139C (enExample)
FR (1) FR2351092A1 (enExample)
GB (1) GB1524747A (enExample)
HU (1) HU179990B (enExample)
IE (1) IE44426B1 (enExample)
IL (1) IL52014A (enExample)
NL (2) NL191793C (enExample)
NO (2) NO147304C (enExample)
NZ (1) NZ183931A (enExample)
PL (2) PL108860B1 (enExample)
SE (2) SE437837B (enExample)
SU (1) SU910116A3 (enExample)
YU (1) YU40672B (enExample)
ZA (1) ZA772433B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55164663A (en) * 1979-06-11 1980-12-22 Syntex Inc Nonapeptide and decapeptide derivatives of progesterone release hormone and its manufacture
EP0779072A1 (en) 1995-12-15 1997-06-18 Takeda Chemical Industries, Ltd. Production of microspheres
EP0781548A2 (en) 1995-12-15 1997-07-02 Takeda Chemical Industries, Ltd. Production of sustained-release preparation for injection
JP2672677B2 (ja) * 1989-02-09 1997-11-05 タツプ・フアーマシユーテイカルズ・インコーポレイテツド Ｌｈｒｈ同族体
WO2003041739A1 (fr) 2001-11-13 2003-05-22 Takeda Chemical Industries, Ltd. Agents anticancer
JP2009227687A (ja) * 2004-06-25 2009-10-08 Takeda Chem Ind Ltd メタスチン誘導体およびその用途

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* Cited by examiner, † Cited by third party
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DE3411224A1 (de) * 1984-03-27 1985-10-10 Hoechst Ag, 6230 Frankfurt Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren
US4666885A (en) * 1985-02-08 1987-05-19 Fernand Labrie Combination therapy for treatment of female breast cancer
US4760053A (en) * 1984-08-02 1988-07-26 Fernand Labrie Combination therapy for selected sex steroid dependent cancers
US4705778A (en) * 1985-10-22 1987-11-10 Sri International Orally active LHRH analogs
JPH0284272U (enExample) * 1988-12-20 1990-06-29
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US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
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WO2021097256A1 (en) 2019-11-14 2021-05-20 Cohbar, Inc. Cxcr4 antagonist peptides
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods

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US4005063A (en) * 1973-10-11 1977-01-25 Abbott Laboratories [Des-gly]10 -GnRH nonapeptide anide analogs in position 6 having ovulation-inducing activity
US3914412A (en) * 1973-10-11 1975-10-21 Abbott Lab {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity
US3901872A (en) * 1974-03-13 1975-08-26 American Home Prod P-glu-his-trp-ser-tyr-d-pgl-leu-arg-pro-gly-nh' 2 'and intermediates
JPS50142563A (enExample) * 1974-04-26 1975-11-17
US3896104A (en) * 1974-05-22 1975-07-22 American Home Prod P-glu-his-trp-ser-tyr-d-lys-leu-arg-pro-gly-nh' 2 'and intermediates
DE2438350C3 (de) * 1974-08-09 1979-06-13 Hoechst Ag, 6000 Frankfurt Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
US3971737A (en) * 1975-03-24 1976-07-27 American Home Products Corporation [2-Methyl-Ala6 ]LRH
US4018726A (en) * 1975-06-12 1977-04-19 Andrew Victor Schally [D-Phe6 ]-LH-RH and intermediates therefor
US4024121A (en) * 1976-01-27 1977-05-17 Schally Andrew Victor (Pyro)-Glu-His-Trp-D-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHR and intermediates
US4010125A (en) * 1975-06-12 1977-03-01 Schally Andrew Victor [D-Trp6 ]-LH-RH and intermediates therefor
US3992530A (en) * 1975-12-08 1976-11-16 American Home Products Corporation [D-2-(1,4-Cyclohexadienyl)gly]6 -des-gly10 -lrh nonapeptide amides

Cited By (7)

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Publication number Priority date Publication date Assignee Title
JPS55164663A (en) * 1979-06-11 1980-12-22 Syntex Inc Nonapeptide and decapeptide derivatives of progesterone release hormone and its manufacture
JPS63264498A (ja) * 1979-06-11 1988-11-01 シンテックス（ユー．エス．エー．）インコーポレイティド 黄体形成ホルモン放出ホルモンのノナペプチド及びデカペプチド誘導体
JP2672677B2 (ja) * 1989-02-09 1997-11-05 タツプ・フアーマシユーテイカルズ・インコーポレイテツド Ｌｈｒｈ同族体
EP0779072A1 (en) 1995-12-15 1997-06-18 Takeda Chemical Industries, Ltd. Production of microspheres
EP0781548A2 (en) 1995-12-15 1997-07-02 Takeda Chemical Industries, Ltd. Production of sustained-release preparation for injection
WO2003041739A1 (fr) 2001-11-13 2003-05-22 Takeda Chemical Industries, Ltd. Agents anticancer
JP2009227687A (ja) * 2004-06-25 2009-10-08 Takeda Chem Ind Ltd メタスチン誘導体およびその用途

Also Published As

Publication number Publication date
ES458691A1 (es) 1978-08-16
DE2720245A1 (de) 1977-11-24
AT379400B (de) 1985-12-27
SE437993B (sv) 1985-03-25
ATA217979A (de) 1981-06-15
YU117277A (en) 1983-02-28
NO147304B (no) 1982-12-06
NL970002I2 (nl) 1997-05-01
IL52014A (en) 1979-11-30
FR2351092B1 (enExample) 1980-02-22
SE7705432L (sv) 1977-11-12
CA1101844A (en) 1981-05-26
US4100274A (en) 1978-07-11
FI771480A7 (enExample) 1977-11-12
DK207977A (da) 1977-11-12
FI64139B (fi) 1983-06-30
DK149596C (da) 1987-01-05
NL7705130A (nl) 1977-11-15
DD136738A5 (de) 1979-07-25
SE437837B (sv) 1985-03-18
CH627151A5 (enExample) 1981-12-31
IE44426B1 (en) 1981-11-18
NO771644L (no) 1977-11-14
CS199673B2 (en) 1980-07-31
CH629475A5 (de) 1982-04-30
YU40672B (en) 1986-04-30
NZ183931A (en) 1979-03-16
PL108860B1 (en) 1980-05-31
ZA772433B (en) 1978-03-29
JPS6113480B2 (enExample) 1986-04-14
NL191793B (nl) 1996-04-01
BE854467A (fr) 1977-11-10
NO149586B (no) 1984-02-06
NL191793C (nl) 1996-08-02
ATA335877A (de) 1985-05-15
AT365562B (de) 1982-01-25
NO149586C (no) 1984-05-16
NL970002I1 (nl) 1997-03-03
PL197889A1 (pl) 1978-02-13
FI64139C (fi) 1983-10-10
GB1524747A (en) 1978-09-13
PL104362B1 (pl) 1979-08-31
SE8007763L (sv) 1980-11-05
AU508025B2 (en) 1980-03-06
IE44426L (en) 1977-11-11
SU910116A3 (ru) 1982-02-28
AU2468177A (en) 1978-11-02
NO147304C (no) 1983-03-16
IL52014A0 (en) 1977-07-31
FR2351092A1 (fr) 1977-12-09
HU179990B (en) 1983-01-28
BG60740B2 (bg) 1996-01-31
DK149596B (da) 1986-08-04
NO822984L (no) 1977-11-14
DE2720245C2 (de) 1986-09-25

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