JP7716823B1 - L-グルタミン酸生産菌およびl-グルタミン酸の製造方法 - Google Patents
L-グルタミン酸生産菌およびl-グルタミン酸の製造方法Info
- Publication number
- JP7716823B1 JP7716823B1 JP2025534317A JP2025534317A JP7716823B1 JP 7716823 B1 JP7716823 B1 JP 7716823B1 JP 2025534317 A JP2025534317 A JP 2025534317A JP 2025534317 A JP2025534317 A JP 2025534317A JP 7716823 B1 JP7716823 B1 JP 7716823B1
- Authority
- JP
- Japan
- Prior art keywords
- acetyl
- coa hydrolase
- glutamic acid
- gene
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/02—Thioester hydrolases (3.1.2)
- C12Y301/02001—Acetyl-CoA hydrolase (3.1.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/15—Corynebacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2023/047152 WO2025141838A1 (ja) | 2023-12-28 | 2023-12-28 | L-グルタミン酸生産菌およびl-グルタミン酸の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2025141838A1 JPWO2025141838A1 (https=) | 2025-07-03 |
| JP7716823B1 true JP7716823B1 (ja) | 2025-08-01 |
| JPWO2025141838A5 JPWO2025141838A5 (https=) | 2025-11-26 |
Family
ID=96217142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025534317A Active JP7716823B1 (ja) | 2023-12-28 | 2023-12-28 | L-グルタミン酸生産菌およびl-グルタミン酸の製造方法 |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4692313A1 (https=) |
| JP (1) | JP7716823B1 (https=) |
| WO (1) | WO2025141838A1 (https=) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006149214A (ja) * | 2004-11-25 | 2006-06-15 | Ajinomoto Co Inc | L−アミノ酸生産菌及びl−アミノ酸の製造方法 |
| JP2007097573A (ja) * | 2004-12-28 | 2007-04-19 | Ajinomoto Co Inc | L−グルタミン酸生産菌及びl−グルタミン酸の製造方法 |
| WO2014185430A1 (ja) * | 2013-05-13 | 2014-11-20 | 味の素株式会社 | L-アミノ酸の製造法 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50113209A (https=) | 1974-02-13 | 1975-09-05 | ||
| JPS5238088A (en) | 1975-09-19 | 1977-03-24 | Ajinomoto Co Inc | Preparation of l-glutamic acid |
| JPS561889A (en) | 1979-06-20 | 1981-01-10 | Ajinomoto Co Inc | Preparation of l-glutamic acid by fermentation |
| JPS5832596B2 (ja) | 1979-08-10 | 1983-07-14 | 味の素株式会社 | 発酵法によるl−グルタミン酸の製造方法 |
| JPS5810075B2 (ja) | 1979-08-31 | 1983-02-24 | 味の素株式会社 | 新規変異株 |
| JPS56140895A (en) | 1980-04-02 | 1981-11-04 | Ajinomoto Co Inc | Preparation of l-glutamic acid by fermentation |
| JPS5765198A (en) | 1980-10-09 | 1982-04-20 | Ajinomoto Co Inc | Fermentative production of l-glutamic acid |
| JPS57134500A (en) | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
| JPS572689A (en) | 1981-03-23 | 1982-01-08 | Ajinomoto Co Inc | Preparation of l-glutamic acid |
| JPS57183799A (en) | 1981-04-17 | 1982-11-12 | Kyowa Hakko Kogyo Co Ltd | Novel plasmid |
| JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドpcg2 |
| JPS58158192A (ja) | 1982-03-15 | 1983-09-20 | Ajinomoto Co Inc | 発酵法によるl−グルタミン酸の製造方法 |
| JPS58192900A (ja) | 1982-05-04 | 1983-11-10 | Ajinomoto Co Inc | 複合プラスミド |
| DE3565475D1 (en) | 1984-04-07 | 1988-11-17 | Bayer Ag | Process and apparatus for the production of granules |
| FR2603581B1 (fr) | 1986-04-28 | 1993-08-13 | Ajinomoto Kk | Procede pour isoler et purifier des aminoacides par chromatographie |
| US4777051A (en) | 1986-06-20 | 1988-10-11 | Ajinomoto Co., Inc. | Process for the production of a composition for animal feed |
| JPH01191686A (ja) | 1988-01-26 | 1989-08-01 | Mitsubishi Petrochem Co Ltd | 複合プラスミド |
| FR2627508B1 (fr) | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
| JP2537260B2 (ja) | 1988-02-23 | 1996-09-25 | 東陶機器株式会社 | 和風便器の施工方法 |
| US5185262A (en) | 1988-07-27 | 1993-02-09 | Mitsubishi Petrochemical Co., Ltd. | DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism |
| JP2678995B2 (ja) | 1988-09-08 | 1997-11-19 | 三菱化学株式会社 | トリプトフアンシンターゼの製造法 |
| JP2973446B2 (ja) | 1990-01-11 | 1999-11-08 | 三菱化学株式会社 | 新規プラスミドベクター |
| JPH0488994A (ja) | 1990-07-30 | 1992-03-23 | Kyowa Hakko Kogyo Co Ltd | 発酵法によるl―グルタミン酸の製造法 |
| JP3393433B2 (ja) | 1991-08-20 | 2003-04-07 | オムロン株式会社 | 画像処理装置および方法 |
| DE4130868C2 (de) | 1991-09-17 | 1994-10-13 | Degussa | Tierfuttermittelsupplement auf der Basis einer Aminosäure und Verfahren zu dessen Herstellung |
| JPH05158192A (ja) | 1991-12-10 | 1993-06-25 | Fuji Photo Film Co Ltd | 写真フイルムパトローネ |
| SK283058B6 (sk) | 1993-10-28 | 2003-02-04 | Ajinomoto Co., Inc. | Spôsob produkcie cieľovej látky použitím mikroorganizmov |
| CN1177380A (zh) | 1995-01-23 | 1998-03-25 | 诺沃挪第克公司 | 通过转座的dna整合 |
| JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
| JP3861341B2 (ja) | 1995-10-13 | 2006-12-20 | 味の素株式会社 | 発酵液の膜除菌方法 |
| JPH09173792A (ja) | 1995-10-23 | 1997-07-08 | Ajinomoto Co Inc | 発酵液の処理方法 |
| DE19621930C1 (de) | 1996-05-31 | 1997-12-11 | Degussa | Verfahren zur Herstellung eines Tierfuttermittel-Zusatzes auf Fermentationsbrühe-Basis |
| JP4168463B2 (ja) | 1996-12-05 | 2008-10-22 | 味の素株式会社 | L−リジンの製造法 |
| CN1179045C (zh) | 1997-08-12 | 2004-12-08 | 味之素株式会社 | 通过发酵生产l-谷氨酸的方法 |
| RU2231552C2 (ru) | 1997-10-04 | 2004-06-27 | Форшунгсцентрум Юлих Гмбх | Способ микробиологического получения аминокислот семейства аспартатов и/или глутаматов и используемые в способе средства |
| EP1070376A1 (de) | 1998-04-09 | 2001-01-24 | Siemens Aktiengesellschaft | Anordnung und verfahren zur elektrischen energieversorgung einer elektrischen last |
| SK7702000A3 (en) | 1998-09-25 | 2000-10-09 | Ajinomoto Kk | Process for preparing coryneform bacteria having an improved amino acid- or nucleic acid-productivity |
| EP1010755B1 (en) | 1998-12-18 | 2010-10-06 | Ajinomoto Co., Inc. | Method for producing L-Glutamic acid by fermentation |
| US6238714B1 (en) | 1999-05-05 | 2001-05-29 | Degussa-Huls Ag | Feedstuff additive which contains D-pantothenic acid and/or its salts and a process for the preparation thereof |
| JP2003159092A (ja) | 1999-07-02 | 2003-06-03 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2003144160A (ja) | 1999-07-02 | 2003-05-20 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP4427878B2 (ja) | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるl−グルタミン酸の製造法 |
| RU2207376C2 (ru) | 1999-10-14 | 2003-06-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислоты методом ферментации, штамм бактерии escherichia coli - продуцент l-аминокислоты (варианты) |
| RU2212447C2 (ru) | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
| DE10022124B4 (de) | 2000-05-06 | 2010-01-14 | Wabco Gmbh | Elektronisches Steuergerät |
| DE60210697T2 (de) | 2001-02-13 | 2007-04-05 | Ajinomoto Co., Inc. | Verfahren zur Produktion von L-Aminosäuren mittels Bakterien der Gattung Escherichia |
| JP4599726B2 (ja) | 2001-02-20 | 2010-12-15 | 味の素株式会社 | L−グルタミン酸の製造法 |
| EP1404856B1 (en) | 2001-07-06 | 2006-07-26 | Degussa AG | Process for the preparation of l-amino acids using strains of the enterobacteriaceae family |
| WO2003008606A2 (en) | 2001-07-18 | 2003-01-30 | Degussa Ag | Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced phob or phor gene |
| RU2005138030A (ru) | 2003-05-07 | 2006-04-20 | Адзиномото Ко., Инк. (Jp) | Способ получения l-глутаминовой кислоты |
| RU2005138514A (ru) | 2003-06-10 | 2006-06-10 | Адзиномото Ко., Инк. (Jp) | Способ получения l-глутаминовой кислоты |
| JP2006340603A (ja) | 2003-06-23 | 2006-12-21 | Ajinomoto Co Inc | L−グルタミン酸の製造法 |
| DE10331366A1 (de) | 2003-07-11 | 2005-01-27 | Degussa Ag | Verfahren zur Granulation eines Tierfuttermittel-Zusatzes |
| BR122019024048B1 (pt) | 2004-12-28 | 2022-05-24 | Ajinomoto Co., Inc | Método para produzir ácido l-glutâmico |
| US7794989B2 (en) | 2004-12-28 | 2010-09-14 | Ajinomoto Co., Inc. | L-glutamic acid-producing microorganism and a method for producing L-glutamic acid |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| WO2008078646A1 (ja) | 2006-12-22 | 2008-07-03 | Ajinomoto Co., Inc. | アミノ酸又は核酸の結晶の分離方法 |
| BRPI0703692B1 (pt) | 2006-12-25 | 2016-12-27 | Ajinomoto Kk | método para se obter os cristais de um hidrocloreto de aminoácido básico compreendendo gerar um aminoácido básico usando células microbianas por fermentação em um caldo de fermentação ou por um método enzimático em uma solução de reação de enzima usando as células como catalisadores |
| WO2013069634A1 (ja) | 2011-11-11 | 2013-05-16 | 味の素株式会社 | 発酵法による目的物質の製造法 |
| JP6097869B1 (ja) | 2016-08-01 | 2017-03-15 | 新日鉄住金エンジニアリング株式会社 | エタノールの製造方法 |
-
2023
- 2023-12-28 JP JP2025534317A patent/JP7716823B1/ja active Active
- 2023-12-28 WO PCT/JP2023/047152 patent/WO2025141838A1/ja active Pending
- 2023-12-28 EP EP23963186.4A patent/EP4692313A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006149214A (ja) * | 2004-11-25 | 2006-06-15 | Ajinomoto Co Inc | L−アミノ酸生産菌及びl−アミノ酸の製造方法 |
| JP2007097573A (ja) * | 2004-12-28 | 2007-04-19 | Ajinomoto Co Inc | L−グルタミン酸生産菌及びl−グルタミン酸の製造方法 |
| WO2014185430A1 (ja) * | 2013-05-13 | 2014-11-20 | 味の素株式会社 | L-アミノ酸の製造法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2025141838A1 (ja) | 2025-07-03 |
| JPWO2025141838A1 (https=) | 2025-07-03 |
| EP4692313A1 (en) | 2026-02-11 |
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