WO2008078646A1 - アミノ酸又は核酸の結晶の分離方法 - Google Patents

アミノ酸又は核酸の結晶の分離方法 Download PDF

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Publication number
WO2008078646A1
WO2008078646A1 PCT/JP2007/074528 JP2007074528W WO2008078646A1 WO 2008078646 A1 WO2008078646 A1 WO 2008078646A1 JP 2007074528 W JP2007074528 W JP 2007074528W WO 2008078646 A1 WO2008078646 A1 WO 2008078646A1
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WIPO (PCT)
Prior art keywords
crystal
amino acid
nucleic acid
separation
slurry
Prior art date
Application number
PCT/JP2007/074528
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English (en)
French (fr)
Inventor
Nobuharu Konishi
Toshihide Miyachi
Wataru Ikeda
Toru Nakamura
Original Assignee
Ajinomoto Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co., Inc. filed Critical Ajinomoto Co., Inc.
Publication of WO2008078646A1 publication Critical patent/WO2008078646A1/ja

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

アミノ酸や核酸の結晶を、微生物細胞を含む発酵液又は酵素反応液から簡便に分離する技術を提供する。アミノ酸又は核酸の結晶、及び微生物細胞を含むスラリーに、同微生物細胞を溶解させる酵素を加えて前記細胞を溶解させ、次いで前記スラリーから結晶を採取することにより、スラリーから結晶を分離する。
PCT/JP2007/074528 2006-12-22 2007-12-20 アミノ酸又は核酸の結晶の分離方法 WO2008078646A1 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006-346014 2006-12-22
JP2006346014 2006-12-22
JP2007-189595 2007-07-20
JP2007189595 2007-07-20

Publications (1)

Publication Number Publication Date
WO2008078646A1 true WO2008078646A1 (ja) 2008-07-03

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ID=39562438

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PCT/JP2007/074528 WO2008078646A1 (ja) 2006-12-22 2007-12-20 アミノ酸又は核酸の結晶の分離方法

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WO (1) WO2008078646A1 (ja)

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009088049A1 (ja) 2008-01-10 2009-07-16 Ajinomoto Co., Inc. 発酵法による目的物質の製造法
WO2010084995A2 (en) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. A method for producing an l-amino acid
WO2011016301A1 (ja) 2009-08-03 2011-02-10 味の素株式会社 ビブリオ属細菌を用いたｌ－リジンの製造法
WO2011024555A1 (ja) 2009-08-28 2011-03-03 味の素株式会社 Ｌ－アミノ酸の製造法
WO2011055710A1 (ja) 2009-11-06 2011-05-12 味の素株式会社 Ｌ－アミノ酸の製造法
EP2345667A2 (en) 2010-01-15 2011-07-20 Ajinomoto Co., Inc. A method for producing an L-amino acid using a bacterium of the enterobacteriaceae family
WO2011096554A1 (ja) 2010-02-08 2011-08-11 味の素株式会社 変異型ｒｐｓＡ遺伝子及びＬ－アミノ酸の製造法
WO2012077739A1 (ja) 2010-12-10 2012-06-14 味の素株式会社 Ｌ－アミノ酸の製造法
WO2012137689A1 (ja) 2011-04-01 2012-10-11 味の素株式会社 Ｌ－システインの製造法
WO2012144472A1 (ja) 2011-04-18 2012-10-26 味の素株式会社 Ｌ－システインの製造法
WO2013069634A1 (ja) 2011-11-11 2013-05-16 味の素株式会社 発酵法による目的物質の製造法
WO2014185430A1 (ja) 2013-05-13 2014-11-20 味の素株式会社 Ｌ－アミノ酸の製造法
EP3165608A1 (en) 2015-10-30 2017-05-10 Ajinomoto Co., Inc. Method for producing l-amino acid of glutamate family
CN106699587A (zh) * 2016-12-19 2017-05-24 宜昌三峡制药有限公司 一种异亮氨酸结晶、洗晶方法及装置
WO2018157133A1 (en) 2017-02-27 2018-08-30 Translate Bio, Inc. Methods for purification of messenger rna
EP3385389A1 (en) 2017-04-03 2018-10-10 Ajinomoto Co., Inc. Method for producing l-amino acid from fructose
WO2022092018A1 (ja) 2020-10-28 2022-05-05 味の素株式会社 Ｌ－アミノ酸の製造法
WO2023013655A1 (ja) 2021-08-02 2023-02-09 味の素株式会社 食品の風味を改善する方法
EP4345166A2 (en) 2022-09-30 2024-04-03 Ajinomoto Co., Inc. Method for producing l-amino acid

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57186493A (en) * 1981-05-11 1982-11-16 Ajinomoto Co Inc Treatment of fermented solution, etc.
JPH01104186A (ja) * 1987-10-17 1989-04-21 Res Assoc Util Of Light Oil Ｌ−トリプトファンの製造法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57186493A (en) * 1981-05-11 1982-11-16 Ajinomoto Co Inc Treatment of fermented solution, etc.
JPH01104186A (ja) * 1987-10-17 1989-04-21 Res Assoc Util Of Light Oil Ｌ−トリプトファンの製造法

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2749652A2 (en) 2008-01-10 2014-07-02 Ajinomoto Co., Inc. A method for producing a target substance by fermentation
WO2009088049A1 (ja) 2008-01-10 2009-07-16 Ajinomoto Co., Inc. 発酵法による目的物質の製造法
WO2010084995A2 (en) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. A method for producing an l-amino acid
WO2011016301A1 (ja) 2009-08-03 2011-02-10 味の素株式会社 ビブリオ属細菌を用いたｌ－リジンの製造法
WO2011024555A1 (ja) 2009-08-28 2011-03-03 味の素株式会社 Ｌ－アミノ酸の製造法
WO2011055710A1 (ja) 2009-11-06 2011-05-12 味の素株式会社 Ｌ－アミノ酸の製造法
EP2345667A2 (en) 2010-01-15 2011-07-20 Ajinomoto Co., Inc. A method for producing an L-amino acid using a bacterium of the enterobacteriaceae family
WO2011096554A1 (ja) 2010-02-08 2011-08-11 味の素株式会社 変異型ｒｐｓＡ遺伝子及びＬ－アミノ酸の製造法
WO2012077739A1 (ja) 2010-12-10 2012-06-14 味の素株式会社 Ｌ－アミノ酸の製造法
WO2012137689A1 (ja) 2011-04-01 2012-10-11 味の素株式会社 Ｌ－システインの製造法
WO2012144472A1 (ja) 2011-04-18 2012-10-26 味の素株式会社 Ｌ－システインの製造法
WO2013069634A1 (ja) 2011-11-11 2013-05-16 味の素株式会社 発酵法による目的物質の製造法
WO2014185430A1 (ja) 2013-05-13 2014-11-20 味の素株式会社 Ｌ－アミノ酸の製造法
EP3165608A1 (en) 2015-10-30 2017-05-10 Ajinomoto Co., Inc. Method for producing l-amino acid of glutamate family
CN106699587A (zh) * 2016-12-19 2017-05-24 宜昌三峡制药有限公司 一种异亮氨酸结晶、洗晶方法及装置
WO2018157133A1 (en) 2017-02-27 2018-08-30 Translate Bio, Inc. Methods for purification of messenger rna
EP3971291A1 (en) 2017-02-27 2022-03-23 Translate Bio, Inc. Methods for purification of messenger rna
EP3385389A1 (en) 2017-04-03 2018-10-10 Ajinomoto Co., Inc. Method for producing l-amino acid from fructose
WO2022092018A1 (ja) 2020-10-28 2022-05-05 味の素株式会社 Ｌ－アミノ酸の製造法
WO2023013655A1 (ja) 2021-08-02 2023-02-09 味の素株式会社 食品の風味を改善する方法
EP4345166A2 (en) 2022-09-30 2024-04-03 Ajinomoto Co., Inc. Method for producing l-amino acid

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