WO2008141523A8 - 一株产精氨酸脱亚氨酶的菌种及其应用 - Google Patents

一株产精氨酸脱亚氨酶的菌种及其应用 Download PDF

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Publication number
WO2008141523A8
WO2008141523A8 PCT/CN2008/000954 CN2008000954W WO2008141523A8 WO 2008141523 A8 WO2008141523 A8 WO 2008141523A8 CN 2008000954 W CN2008000954 W CN 2008000954W WO 2008141523 A8 WO2008141523 A8 WO 2008141523A8
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WO
WIPO (PCT)
Prior art keywords
arginine deiminase
producing
cgmcc
strain
producing arginine
Prior art date
Application number
PCT/CN2008/000954
Other languages
English (en)
French (fr)
Other versions
WO2008141523A1 (zh
Inventor
Zhihao Sun
Pu Zheng
Ye Ni
Yongmei Liu
Yupeng Liu
Original Assignee
Univ Jiangnan
Zhihao Sun
Pu Zheng
Ye Ni
Yongmei Liu
Yupeng Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Jiangnan, Zhihao Sun, Pu Zheng, Ye Ni, Yongmei Liu, Yupeng Liu filed Critical Univ Jiangnan
Publication of WO2008141523A1 publication Critical patent/WO2008141523A1/zh
Publication of WO2008141523A8 publication Critical patent/WO2008141523A8/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/50Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
PCT/CN2008/000954 2007-05-17 2008-05-19 一株产精氨酸脱亚氨酶的菌种及其应用 WO2008141523A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200710107822A CN100584940C (zh) 2007-05-17 2007-05-17 一株产精氨酸脱亚氨酶的菌种及其应用
CN200710107822.X 2007-05-17

Publications (2)

Publication Number Publication Date
WO2008141523A1 WO2008141523A1 (zh) 2008-11-27
WO2008141523A8 true WO2008141523A8 (zh) 2009-07-30

Family

ID=39084424

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2008/000954 WO2008141523A1 (zh) 2007-05-17 2008-05-19 一株产精氨酸脱亚氨酶的菌种及其应用

Country Status (2)

Country Link
CN (1) CN100584940C (zh)
WO (1) WO2008141523A1 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100584940C (zh) * 2007-05-17 2010-01-27 江南大学 一株产精氨酸脱亚氨酶的菌种及其应用
EP2295560A1 (en) 2009-09-14 2011-03-16 RWTH Aachen University Directed evolution of arginine deiminase for increased activity at physiological pH
CN101935626B (zh) * 2010-06-12 2011-12-21 南京农业大学 一种二甲基甲酰胺降解菌及其生产的菌剂
CN102061283B (zh) * 2010-12-05 2012-08-22 江南大学 一株产精氨酸脱亚胺酶的重组菌的构建及其定向改造方法
CN102433290B (zh) * 2012-01-16 2013-06-12 江南大学 一株产瓜氨酸的菌株及用该菌株生物合成瓜氨酸的方法
CN102433289B (zh) * 2012-01-16 2013-02-27 江南大学 一株产瓜氨酸的菌株及用该菌株生物合成瓜氨酸的方法
CN103468664B (zh) * 2013-10-11 2015-04-15 山东大学 一种促进精氨酸脱亚氨基酶高效水溶性表达的方法
CN103923898A (zh) * 2014-04-17 2014-07-16 江南大学 一种peg修饰的重组精氨酸脱亚胺酶及其制备方法和应用
CN104312953B (zh) * 2014-10-17 2018-08-28 江南大学 一种高效筛选能充分利用瓜氨酸的乳酸菌的方法
CN108265068B (zh) * 2016-12-31 2021-06-15 江苏众红生物工程创药研究院有限公司 重组精氨酸脱亚胺酶及其产业化制备方法和应用
CN110452862B (zh) * 2019-07-22 2022-06-07 山东大学 一种荧光假单胞菌菌株及其应用
CN111018130B (zh) * 2019-12-11 2022-06-03 福建大北农水产科技有限公司 一种水产微生态制剂及其在降低养殖水体中氨氮和亚硝酸盐的应用
CN113430129A (zh) * 2021-05-28 2021-09-24 河北圣雪大成制药有限责任公司 一种去甲四环素高产菌株的筛选方法及培养基
CN113881724A (zh) * 2021-09-30 2022-01-04 新泰市佳禾生物科技有限公司 一种精氨酸转瓜氨酸的提取纯化方法
CN114381402B (zh) * 2022-01-20 2022-12-16 广州大学 一株耐酸耐碱快速脱氮的好氧反硝化细菌、菌剂及其应用
CN115851540B (zh) * 2022-12-13 2023-06-06 广州大学 具有耐盐特性的异养硝化好氧反硝化脱氮除磷菌株及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4915794B2 (zh) * 1971-11-26 1974-04-17
IT1298918B1 (it) * 1998-02-20 2000-02-07 Mendes Srl Uso di batteri dotati di arginina deiminasi per indurre apoptosi e/o ridurre una reazione infiammatoria e composizioni farmaceutiche
KR100654383B1 (ko) * 2006-02-08 2006-12-06 재단법인서울대학교산학협력재단 락토코커스 락티스로부터 분리된 adi 분획물을 유효성분으로 함유하는 암세포 증식 억제용 식품 조성물
CN100584940C (zh) * 2007-05-17 2010-01-27 江南大学 一株产精氨酸脱亚氨酶的菌种及其应用

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Publication number Publication date
WO2008141523A1 (zh) 2008-11-27
CN100584940C (zh) 2010-01-27
CN101121925A (zh) 2008-02-13

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