WO2008016380A3 - Installation of genomes or partial genomes into cells or cell-like systems - Google Patents

Installation of genomes or partial genomes into cells or cell-like systems Download PDF

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Publication number
WO2008016380A3
WO2008016380A3 PCT/US2006/049231 US2006049231W WO2008016380A3 WO 2008016380 A3 WO2008016380 A3 WO 2008016380A3 US 2006049231 W US2006049231 W US 2006049231W WO 2008016380 A3 WO2008016380 A3 WO 2008016380A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell
genome
genomes
manmade
systems
Prior art date
Application number
PCT/US2006/049231
Other languages
French (fr)
Other versions
WO2008016380A2 (en
Inventor
John I Glass
Lei Young
Carole Lartigue
Nacyra Assad-Garcia
Hamilton O Smith
Clyde Hutchison
J Craig Venter
Original Assignee
Craig Venter Inst J
John I Glass
Lei Young
Carole Lartigue
Nacyra Assad-Garcia
Hamilton O Smith
Clyde Hutchison
J Craig Venter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Craig Venter Inst J, John I Glass, Lei Young, Carole Lartigue, Nacyra Assad-Garcia, Hamilton O Smith, Clyde Hutchison, J Craig Venter filed Critical Craig Venter Inst J
Priority to CA2643136A priority Critical patent/CA2643136C/en
Priority to EP06851502.2A priority patent/EP1963515B1/en
Priority to JP2008547655A priority patent/JP2009521229A/en
Priority to AU2006346810A priority patent/AU2006346810B2/en
Priority to DK06851502.2T priority patent/DK1963515T3/en
Publication of WO2008016380A2 publication Critical patent/WO2008016380A2/en
Publication of WO2008016380A3 publication Critical patent/WO2008016380A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Abstract

A method is provided for introducing a genome into a cell or cell-like system. The introduced genome may occur in nature, be manmade with or without automation, or may be a hybrid of naturally occurring and manmade materials. The genome is obtained outside of a cell with minimal damage. Materials such as a proteins, RNAs, polycations, nucleoid condensation proteins, or gene translation systems may accompany the genome. The genome is installed into a naturally occurring cell or into a manmade cell-like system. A cell-like system or synthetic cell resulting from the practice of the provided method may be designed and used to yield gene- expression products, such as desired proteins. By enabling the synthesis of cells or cell-like systems comprising a wide variety of genomes, accompanying materials and membrane types, the provided method makes possible a broader field of experimentation and bioengineering than has been available using prior art methods.
PCT/US2006/049231 2005-12-23 2006-12-22 Installation of genomes or partial genomes into cells or cell-like systems WO2008016380A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2643136A CA2643136C (en) 2005-12-23 2006-12-22 Installation of genomes or partial genomes into cells or cell-like systems
EP06851502.2A EP1963515B1 (en) 2005-12-23 2006-12-22 Installation of genomes or partial genomes into cells or cell-like systems
JP2008547655A JP2009521229A (en) 2005-12-23 2006-12-22 Installing genomes or partial genomes into cells or cell-like systems
AU2006346810A AU2006346810B2 (en) 2005-12-23 2006-12-22 Installation of genomes or partial genomes into cells or cell-like systems
DK06851502.2T DK1963515T3 (en) 2005-12-23 2006-12-22 Integration of genomes or sub-genomes into cells or cell-like systems

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75296505P 2005-12-23 2005-12-23
US60/752,965 2005-12-23

Publications (2)

Publication Number Publication Date
WO2008016380A2 WO2008016380A2 (en) 2008-02-07
WO2008016380A3 true WO2008016380A3 (en) 2008-08-07

Family

ID=38997603

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/049231 WO2008016380A2 (en) 2005-12-23 2006-12-22 Installation of genomes or partial genomes into cells or cell-like systems

Country Status (8)

Country Link
US (1) US9434974B2 (en)
EP (1) EP1963515B1 (en)
JP (1) JP2009521229A (en)
AU (1) AU2006346810B2 (en)
CA (1) CA2643136C (en)
DK (1) DK1963515T3 (en)
TW (1) TWI472619B (en)
WO (1) WO2008016380A2 (en)

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IL117175A (en) 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
US6919434B1 (en) 1995-02-20 2005-07-19 Sankyo Co., Ltd. Monoclonal antibodies that bind OCIF
JP5637846B2 (en) * 2007-05-01 2014-12-10 シンセティック ゲノミクス、インク． Genome integration methods in recipient host cells
US20090017513A1 (en) * 2007-07-13 2009-01-15 Georgia Belle Plantation, Inc. Process for producing hydrocarbon molecules from renewable biomass
US9267132B2 (en) 2007-10-08 2016-02-23 Synthetic Genomics, Inc. Methods for cloning and manipulating genomes
US9259662B2 (en) 2008-02-22 2016-02-16 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
US10093552B2 (en) 2008-02-22 2018-10-09 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
PL2250276T3 (en) 2008-02-23 2017-07-31 James Weifu Lee Designer organisms for photobiological butanol production from carbon dioxide and water
US8986963B2 (en) * 2008-02-23 2015-03-24 James Weifu Lee Designer calvin-cycle-channeled production of butanol and related higher alcohols
CN102015995B (en) 2008-03-03 2014-10-22 焦耳无限科技公司 Engineered CO2 fixing microorganisms producing carbon-based products of interest
EP2998402A1 (en) 2008-10-17 2016-03-23 Joule Unlimited Technologies, Inc. Ethanol production by microorganisms
DK2403944T3 (en) * 2009-03-06 2019-05-27 Synthetic Genomics Inc METHODS FOR CLONING AND MANIPULATING GENOMES
US7794969B1 (en) 2009-07-09 2010-09-14 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
WO2011038134A1 (en) 2009-09-25 2011-03-31 Ls9, Inc. Production of fatty acid derivatives
US20110269119A1 (en) 2009-10-30 2011-11-03 Synthetic Genomics, Inc. Encoding text into nucleic acid sequences
EP2542676A1 (en) * 2010-03-05 2013-01-09 Synthetic Genomics, Inc. Methods for cloning and manipulating genomes
AU2011302092A1 (en) 2010-09-14 2013-04-11 Joule Unlimited Technologies, Inc. Methods and compositions for the extracellular transport of biosynthetic hydrocarbons and other molecules
US8349587B2 (en) 2011-10-31 2013-01-08 Ginkgo Bioworks, Inc. Methods and systems for chemoautotrophic production of organic compounds
US8790901B2 (en) 2011-12-14 2014-07-29 Pronutria, Inc. Microorganisms and methods for producing unsaturated fatty acids
EP3715365A1 (en) 2012-03-26 2020-09-30 Axcella Health Inc. Nutritive fragments, proteins and methods
US20150315599A1 (en) 2012-12-07 2015-11-05 Ginkgo Bioworks, Inc Methods and Systems for Methylotrophic Production of Organic Compounds
CA2925521A1 (en) 2013-09-25 2015-04-02 Pronutria Biosciences, Inc. Compositions and formulations for prevention and treatment of diabetes and obesity, and methods of production and use thereof in glucose and caloric control
WO2015048339A2 (en) 2013-09-25 2015-04-02 Pronutria, Inc. Compositions and formulations for non-human nutrition and methods of production and use thereof
WO2015054507A1 (en) 2013-10-10 2015-04-16 Pronutria, Inc. Nutritive polypeptide production systems, and methods of manufacture and use thereof
EP3430133A1 (en) 2016-03-17 2019-01-23 INVISTA Textiles (U.K.) Limited Carboxylic acid reductase polypeptides and variants having improved activity, materials and processes relating thereto
DK3433354T3 (en) 2016-03-23 2024-01-22 Synthetic Genomics Inc GENERATION OF SYNTHETIC GENOMES
JP2020506702A (en) 2017-02-02 2020-03-05 カーギル インコーポレイテッド Genetically modified cells producing C6-C10 fatty acid derivatives
CN111836897B (en) 2018-03-30 2023-10-17 英威达纺织（英国）有限公司 Method for controlling oxygen concentration during aerobic biosynthesis
CN111936623B (en) 2018-03-30 2023-08-25 英威达纺织（英国）有限公司 Material and method for biosynthesis of pimelic acid and use of synthetic polypeptides
WO2019213108A1 (en) 2018-05-02 2019-11-07 Invista Textiles (U.K.) Ltd. Methods for controlling limitation conditions in product biosynthesis for non-phb generating cupriavidus or ralstonia

Citations (1)

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Publication number Priority date Publication date Assignee Title
US6521427B1 (en) * 1997-09-16 2003-02-18 Egea Biosciences, Inc. Method for the complete chemical synthesis and assembly of genes and genomes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6521427B1 (en) * 1997-09-16 2003-02-18 Egea Biosciences, Inc. Method for the complete chemical synthesis and assembly of genes and genomes

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHECK E.: "Venter aims for maximum impact with minimal genome", NATURE, vol. 420, 28 November 2002 (2002-11-28), pages 350, XP008128716 *
HUTCHISON ET AL.: "Global Transposon Mutagenesis and a Mineral Mycoplasma Genome", SCIENCE, vol. 286, 10 December 1999 (1999-12-10), pages 2165 - 2169, XP008128717 *
See also references of EP1963515A4 *
SMITH ET AL.: "Generating a synthetic genome by whole genome assembly: PhiX174 bacteriophage from synthetic oligonucleotides", PROC. NATL. ACAD. SCI., vol. 100, no. 26, 23 December 2003 (2003-12-23), pages 15440 - 15445, XP008128718 *

Also Published As

Publication number Publication date
DK1963515T3 (en) 2014-09-01
JP2009521229A (en) 2009-06-04
WO2008016380A2 (en) 2008-02-07
US20070269862A1 (en) 2007-11-22
CA2643136C (en) 2017-04-18
AU2006346810A1 (en) 2008-02-07
EP1963515B1 (en) 2014-05-28
TWI472619B (en) 2015-02-11
TW200745336A (en) 2007-12-16
AU2006346810B2 (en) 2013-05-02
EP1963515A2 (en) 2008-09-03
EP1963515A4 (en) 2009-10-21
US9434974B2 (en) 2016-09-06
CA2643136A1 (en) 2008-02-07

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