JP7538724B2 - 細胞保護の方法と組成物 - Google Patents

細胞保護の方法と組成物 Download PDF

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JP7538724B2
JP7538724B2 JP2020570916A JP2020570916A JP7538724B2 JP 7538724 B2 JP7538724 B2 JP 7538724B2 JP 2020570916 A JP2020570916 A JP 2020570916A JP 2020570916 A JP2020570916 A JP 2020570916A JP 7538724 B2 JP7538724 B2 JP 7538724B2
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chondroitin sulfate
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リュー ジアン
リ ジン
ス グオウェイ
パウリンスキー ラファル
スパーケンバウ エリカ
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University of North Carolina at Chapel Hill
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2020570916A 2018-06-20 2019-06-19 細胞保護の方法と組成物 Active JP7538724B2 (ja)

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US201862687540P 2018-06-20 2018-06-20
US62/687,540 2018-06-20
PCT/US2019/037993 WO2019246264A1 (en) 2018-06-20 2019-06-19 Cell protective methods and compositions

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JP2021528421A JP2021528421A (ja) 2021-10-21
JP2021528421A5 JP2021528421A5 (https=) 2022-06-27
JPWO2019246264A5 JPWO2019246264A5 (https=) 2022-06-27
JP7538724B2 true JP7538724B2 (ja) 2024-08-22

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US (2) US11633424B2 (https=)
EP (1) EP3810152A4 (https=)
JP (1) JP7538724B2 (https=)
CN (1) CN112437667B (https=)
WO (1) WO2019246264A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12397016B2 (en) 2017-11-03 2025-08-26 The University Of North Carolina At Chapel Hill Sulfated oligosaccharides having anti-inflammatory activity
US12539311B2 (en) 2017-03-10 2026-02-03 The University Of North Carolina At Chapel Hill Short-acting heparin-based anticoagulant compounds and methods
US12569512B2 (en) 2019-11-13 2026-03-10 The University Of North Carolina At Chapel Hill Heparan sulfate (HS) oligosaccharides effect in liver ischemia reperfusion injury

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019010216A1 (en) * 2017-07-03 2019-01-10 The University Of North Carolina At Chapel Hill ENZYMATIC SYNTHESIS OF HOMOGENEOUS CHONDROITIN SULFATE OLIGOSACCHARIDES
CN116254296A (zh) * 2023-03-27 2023-06-13 中国科学院微生物研究所 利用昆虫细胞杆状病毒表达系统表达硫酸软骨素修饰酶的方法及应用
CN116254295A (zh) * 2023-03-27 2023-06-13 中国科学院微生物研究所 利用昆虫细胞杆状病毒表达系统表达软骨素6-o-硫酸转移酶的方法及应用

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US20060229276A1 (en) 2004-07-28 2006-10-12 Magnus Hook Use of glycosoaminoglycans for the prevention and treatment of sepsis

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12539311B2 (en) 2017-03-10 2026-02-03 The University Of North Carolina At Chapel Hill Short-acting heparin-based anticoagulant compounds and methods
US12397016B2 (en) 2017-11-03 2025-08-26 The University Of North Carolina At Chapel Hill Sulfated oligosaccharides having anti-inflammatory activity
US12569512B2 (en) 2019-11-13 2026-03-10 The University Of North Carolina At Chapel Hill Heparan sulfate (HS) oligosaccharides effect in liver ischemia reperfusion injury

Also Published As

Publication number Publication date
WO2019246264A1 (en) 2019-12-26
CN112437667A (zh) 2021-03-02
EP3810152A4 (en) 2022-04-27
JP2021528421A (ja) 2021-10-21
EP3810152A1 (en) 2021-04-28
CN112437667B (zh) 2024-05-28
US20230277580A1 (en) 2023-09-07
US11633424B2 (en) 2023-04-25
US20210260098A1 (en) 2021-08-26

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