|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
IT1232939B
(it)
|
1987-11-06 |
1992-03-10 |
Opocrin Spa |
Eparan solfato caratterizzato da elevata attivita' antitrombotica, elevata biodisponibilita', assenza di attivita' anticoagulante; suo processo di estrazione da organi e da tessuti e relative composizioni farmaceutiche
|
|
US4865870A
(en)
|
1988-07-07 |
1989-09-12 |
Becton, Dickinson And Company |
Method for rendering a substrate surface antithrombogenic
|
|
PT93847A
(pt)
|
1989-04-24 |
1990-11-20 |
Harvard College |
Processo para a preparacao de oligossacaridos de baixo peso molecular derivados de heparina ou de sulfato de heparano despolimerizados e de composicoes farmaceuticas que os contem
|
|
US5378829A
(en)
|
1990-04-23 |
1995-01-03 |
Akzo N.V. |
Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
|
|
WO1993005167A1
(en)
|
1991-09-06 |
1993-03-18 |
Children's Medical Center Corporation |
Cell-type specific heparan sulfate proteoglycans and their uses
|
|
IT1260137B
(it)
|
1992-04-17 |
1996-03-28 |
Alfa Wassermann Spa |
Glicosaminoglicani semisintetici a struttura eparinica od eparanica modificati nella posizione 2 dell'acido alfa-l-iduronico-2-0-solfato
|
|
JP3818676B2
(ja)
|
1994-07-22 |
2006-09-06 |
生化学工業株式会社 |
ヘパラン硫酸6−o−硫酸基転移酵素
|
|
IT1271057B
(it)
|
1994-11-04 |
1997-05-26 |
Inalco Spa |
Polisaccaridi aventi un elevato contenuto di acido iduronico
|
|
JP3672359B2
(ja)
|
1995-07-24 |
2005-07-20 |
生化学工業株式会社 |
ヘパラン硫酸 2−o−硫酸基転移酵素
|
|
DK0852491T3
(da)
|
1995-09-29 |
2004-12-20 |
Biomarin Pharm Inc |
Anvendelse af heparinaser til at mindske inflammatoriske responser
|
|
US5935824A
(en)
|
1996-01-31 |
1999-08-10 |
Technologene, Inc. |
Protein expression system
|
|
US6861254B1
(en)
|
1997-10-24 |
2005-03-01 |
Massachusetts Institute Of Technology |
Heparan sulfate D-glucosaminyl 3-O-sulfotransferases, and uses therefor
|
|
US8088604B2
(en)
|
1998-04-02 |
2012-01-03 |
The Board Of Regents Of The University Of Oklahoma |
Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases
|
|
US7307159B2
(en)
|
2001-05-08 |
2007-12-11 |
The Board Of Regents Of The University Of Oklahoma |
Heparin/heparosan synthase from P. multocida and methods of making and using same
|
|
US6624141B1
(en)
|
1999-03-17 |
2003-09-23 |
The Regents Of The University Of Michigan |
Protamine fragment compositions and methods of use
|
|
US6255088B1
(en)
|
1999-05-11 |
2001-07-03 |
The Scripps Research Institute |
Enzymatic sulfation of biomolecules
|
|
US7101859B2
(en)
*
|
2000-01-10 |
2006-09-05 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Use of lipid conjugates in the treatment of diseases
|
|
DE60140941D1
(de)
|
2000-07-07 |
2010-02-11 |
Seikagaku Kogyo Co Ltd |
Hyaluronsäure oligosaccharid fraktionen und medikamente, die diese enthalten
|
|
US8067196B2
(en)
|
2001-03-28 |
2011-11-29 |
Massachusetts Institute Of Technology |
6-O sulfated polysaccharides and methods of preparation thereof
|
|
DK2070939T3
(da)
|
2001-05-25 |
2014-06-23 |
Univ Duke |
Modulatorer af farmakologiske midler
|
|
WO2003018598A2
(en)
|
2001-08-30 |
2003-03-06 |
University College Dublin |
Monosaccharide derivatives
|
|
AU2003247808A1
(en)
|
2002-07-05 |
2004-01-23 |
Anders Malmstrom |
Purified and isolated heparan sulfate 3-o-sulfotransferase isoform 5 nucleic acids and polypeptides and therapeutic and screening methods using same
|
|
GB0216861D0
(en)
|
2002-07-19 |
2002-08-28 |
Univ Birmingham |
Saccharide libraries
|
|
AU2003262794A1
(en)
|
2002-08-23 |
2004-03-11 |
Neose Technologies, Inc. |
Total synthesis of heparin
|
|
WO2005014619A2
(en)
|
2003-03-28 |
2005-02-17 |
Thomas Jefferson University |
Heparin-binding peptides and uses thereof
|
|
DE60336400D1
(de)
|
2003-10-24 |
2011-04-28 |
3M Innovative Properties Co |
Wässrige Dispersionen von Polytetrafluorethylenteilchen
|
|
US7655445B2
(en)
|
2003-11-12 |
2010-02-02 |
Massachusetts Institute Of Technology |
Methods for synthesis of sulfated saccharides
|
|
US7638503B2
(en)
*
|
2004-05-26 |
2009-12-29 |
California Institute Of Technology |
Small molecule stimulators of neuronal growth
|
|
WO2006015171A2
(en)
*
|
2004-07-28 |
2006-02-09 |
The Texas A & M University System |
Use of glycosoaminoglycans for the prevention and treatment of sepsis
|
|
EP1885865A4
(en)
|
2005-05-12 |
2010-12-22 |
Univ North Carolina |
ENZYMATIC SYNTHESIS OF SULFATED POLYSACCHARIDES
|
|
EP2447285A3
(en)
|
2006-05-25 |
2013-01-16 |
Momenta Pharmaceuticals, Inc. |
Low molecular weight heparin composition and uses thereof
|
|
WO2009014715A2
(en)
|
2007-07-23 |
2009-01-29 |
The University Of North Carolina At Chapel Hill |
Enzymatic synthesis of sulfated polysaccharides without iduronic acid residues
|
|
ES2567079T3
(es)
|
2007-11-02 |
2016-04-19 |
Momenta Pharmaceuticals, Inc. |
Composiciones de polisacáridos que no son anticoagulantes
|
|
MX2011004907A
(es)
|
2008-11-14 |
2011-07-29 |
Portola Pharm Inc |
Antidotos para inhibidores del factor xa y metodos para el uso de los mismos en combinacion con agentes de coagulacion de sangre.
|
|
BRPI1007325A2
(pt)
*
|
2009-02-02 |
2019-09-24 |
Otsuka Pharma Co Ltd |
"baixo peso molecular de polissulfatados derivados de ácido hialurônico e medicamentos que contenham o mesmo."
|
|
AU2010233151A1
(en)
|
2009-04-09 |
2011-11-17 |
The University Of North Carolina At Chapel Hill |
Methods of treating edema related to ischemia-reperfusion
|
|
US20110054236A1
(en)
|
2009-08-25 |
2011-03-03 |
The Regents Of The University Of Michigan |
Compositions and methods for targeting tumors
|
|
US20120322760A1
(en)
|
2009-09-23 |
2012-12-20 |
Momenta Pharmaceuticals, Inc. |
Methods of treatment with a low molecular weight heparin composition
|
|
JP2014501730A
(ja)
*
|
2010-12-01 |
2014-01-23 |
ジ オーストラリアン ナショナル ユニバーシティ |
ヒストン阻害
|
|
WO2012088416A2
(en)
|
2010-12-23 |
2012-06-28 |
The University Of North Carolina At Chapel Hill |
Chemoenzymatic synthesis of structurally homogeneous ultra-low molecular weight heparins
|
|
WO2012116048A1
(en)
|
2011-02-22 |
2012-08-30 |
Rensselaer Polytechnic Institute |
Single step heparosan n-deacetylation and depolymerization for making bioengineered heparin
|
|
WO2012162789A1
(en)
|
2011-06-01 |
2012-12-06 |
University Of British Columbia |
Polymers for reversing heparin-based anticoagulation
|
|
CN105188750A
(zh)
|
2013-03-08 |
2015-12-23 |
德国杰特贝林生物制品有限公司 |
治疗和预防远端缺血-再灌注损伤
|
|
JP6670235B2
(ja)
|
2013-06-17 |
2020-03-18 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill |
可逆的ヘパリン分子、その製法及びその使用方法
|
|
CN116622006B
(zh)
|
2017-03-10 |
2025-05-30 |
北卡罗来纳大学查珀尔希尔分校 |
短效的基于肝素的抗凝血剂化合物和方法
|
|
US11993627B2
(en)
*
|
2017-07-03 |
2024-05-28 |
The University Of North Carolina At Chapel Hill |
Enzymatic synthesis of homogeneous chondroitin sulfate oligosaccharides
|
|
JP7495061B2
(ja)
|
2017-11-03 |
2024-06-04 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
抗炎症作用を有する硫酸化オリゴ糖
|
|
JP7801217B2
(ja)
|
2019-11-13 |
2026-01-16 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
肝虚血再灌流障害におけるヘパラン硫酸(hs)オリゴ糖の効果
|