JP2009520695A5 - - Google Patents
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- Publication number
- JP2009520695A5 JP2009520695A5 JP2008545125A JP2008545125A JP2009520695A5 JP 2009520695 A5 JP2009520695 A5 JP 2009520695A5 JP 2008545125 A JP2008545125 A JP 2008545125A JP 2008545125 A JP2008545125 A JP 2008545125A JP 2009520695 A5 JP2009520695 A5 JP 2009520695A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- group
- solvate
- hydrate
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 27
- 150000003839 salts Chemical class 0.000 claims 11
- 239000012453 solvate Substances 0.000 claims 11
- 125000001072 heteroaryl group Chemical group 0.000 claims 10
- 125000003118 aryl group Chemical group 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000003107 substituted aryl group Chemical group 0.000 claims 2
- 125000006163 5-membered heteroaryl group Chemical group 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 230000003385 bacteriostatic effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 0 CC(*)(C1)C(*)C(C(NO)=O)N1C(*)=O Chemical compound CC(*)(C1)C(*)C(C(NO)=O)N1C(*)=O 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75060005P | 2005-12-15 | 2005-12-15 | |
| PCT/IB2006/003549 WO2007069020A2 (en) | 2005-12-15 | 2006-12-04 | N-hydroxyamide derivatives possessing antibacterial activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009520695A JP2009520695A (ja) | 2009-05-28 |
| JP2009520695A5 true JP2009520695A5 (https=) | 2010-01-28 |
Family
ID=38163279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545125A Pending JP2009520695A (ja) | 2005-12-15 | 2006-12-04 | 抗菌活性を有するｎ−ヒドロキシアミド誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8088804B2 (https=) |
| EP (2) | EP1963262A2 (https=) |
| JP (1) | JP2009520695A (https=) |
| CA (1) | CA2634005C (https=) |
| WO (1) | WO2007069020A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1539744A4 (en) | 2002-07-11 | 2007-06-06 | Vicuron Pharm Inc | N-HYDROXYAMIDE DERIVATIVES WITH ANTIBACTERIAL EFFECT |
| TWI519508B (zh) | 2007-06-12 | 2016-02-01 | Achaogen Inc | 抗菌劑 |
| JP2011517313A (ja) | 2007-12-11 | 2011-06-02 | ビアメト ファーマシューティカルズ，インク． | 金属結合部分を標的化部分と組み合わせて使用する金属酵素阻害剤 |
| EP2326619B1 (en) | 2008-08-01 | 2019-02-27 | Bioxiness Pharmaceuticals, Inc. | Methionine analogs and methods of using same |
| JP5524215B2 (ja) | 2008-09-19 | 2014-06-18 | ファイザー・インク | 抗菌剤として有用なヒドロキサム酸誘導体 |
| US8835498B2 (en) * | 2008-11-19 | 2014-09-16 | Pola Chemical Industries Inc. | Anti-wrinkle agents |
| WO2011045703A2 (en) * | 2009-10-13 | 2011-04-21 | Pfizer Inc. | C-linked hydroxamic acid derivatives useful as antibacterial agents |
| WO2011073845A1 (en) | 2009-12-16 | 2011-06-23 | Pfizer Inc. | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| WO2011132712A1 (ja) | 2010-04-20 | 2011-10-27 | 大正製薬株式会社 | 新規なヒドロキサム酸誘導体 |
| ES2626457T3 (es) | 2011-03-07 | 2017-07-25 | Pfizer Inc. | Derivados de fluoro-piridinona útiles como agentes antibacterianos |
| ES2526687T3 (es) | 2011-04-08 | 2015-01-14 | Pfizer Inc. | Derivados de isoxazol útiles como agentes antibacterianos |
| CA2830866A1 (en) * | 2011-04-08 | 2012-10-11 | Pfizer Inc. | Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents |
| JP6006609B2 (ja) * | 2011-10-19 | 2016-10-12 | 大正製薬株式会社 | 新規なヒドロキサム酸誘導体を含有する医薬 |
| EP2847168A1 (en) | 2012-05-10 | 2015-03-18 | Achaogen, Inc. | Antibacterial agents |
| DK2975022T3 (da) | 2013-03-15 | 2019-07-15 | Fujifilm Toyama Chemical Co Ltd | Hidtil ukendt hydroxaminsyrederivat eller salt deraf |
| EP2883876A1 (en) | 2013-12-16 | 2015-06-17 | Actelion Pharmaceuticals Ltd. | Stereoselective synthesis of substituted pyrrolidines |
| JPWO2016039432A1 (ja) | 2014-09-12 | 2017-06-22 | 富山化学工業株式会社 | 新規なヒドロキサム酸誘導体および抗菌性物質を組み合わせて使用する方法 |
| BR112017004798A2 (pt) | 2014-09-12 | 2017-12-12 | Toyama Chemical Co Ltd | composição farmacêutica que contém um derivado de ácido hidroxâmico ou um seu sal |
| CN108569991A (zh) * | 2018-05-31 | 2018-09-25 | 常州制药厂有限公司 | 一种抗丙肝病毒药物关键中间体的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4077998A (en) * | 1975-10-28 | 1978-03-07 | Morton-Norwich Products, Inc. | Phthaloyl amino acid hydroxamic acids |
| CA2227237C (en) | 1995-07-26 | 2005-12-13 | Pfizer Inc. | N-(aroyl)glycine hydroxamic acid derivatives and related compounds |
| US6693123B2 (en) * | 1995-11-06 | 2004-02-17 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| EP0873123B1 (en) * | 1995-11-06 | 2003-04-09 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US5925659A (en) | 1996-05-07 | 1999-07-20 | Merck & Co., Inc. | Antibacterial agents |
| CA2298617A1 (en) * | 1997-07-31 | 1999-02-11 | Yetunde Olabisi Taiwo | Acyclic metalloprotease inhibitors |
| US6784173B2 (en) * | 2001-06-15 | 2004-08-31 | Hoffmann-La Roche Inc. | Aromatic dicarboxylic acid derivatives |
| EP1539744A4 (en) * | 2002-07-11 | 2007-06-06 | Vicuron Pharm Inc | N-HYDROXYAMIDE DERIVATIVES WITH ANTIBACTERIAL EFFECT |
| KR101076018B1 (ko) | 2003-01-08 | 2011-10-21 | 유니버시티 오브 워싱톤 | 항균제 |
| US7208601B2 (en) * | 2003-08-08 | 2007-04-24 | Mjalli Adnan M M | Aryl and heteroaryl compounds, compositions, and methods of use |
| DE10348023A1 (de) | 2003-10-15 | 2005-05-19 | Imtm Gmbh | Neue Alanyl-Aminopeptidasen-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
| JP2008508348A (ja) * | 2004-08-02 | 2008-03-21 | ジェンメディカ・セラピューティックス・ソシエダッド・リミターダ | 銅含有アミンオキシダーゼを阻害するための化合物およびその使用 |
| WO2006040646A1 (en) * | 2004-10-14 | 2006-04-20 | Pfizer, Inc. | Benzimidazole or indole amides as inhibitors of pin1 |
| US20100152188A1 (en) * | 2005-08-05 | 2010-06-17 | Akella Satya Surya Visweswara Srinivas | Novel Heterocyclic Compounds |
-
2006
- 2006-12-04 JP JP2008545125A patent/JP2009520695A/ja active Pending
- 2006-12-04 US US12/097,307 patent/US8088804B2/en not_active Expired - Fee Related
- 2006-12-04 CA CA2634005A patent/CA2634005C/en not_active Expired - Fee Related
- 2006-12-04 EP EP06821047A patent/EP1963262A2/en not_active Withdrawn
- 2006-12-04 EP EP11151502A patent/EP2338878A3/en not_active Withdrawn
- 2006-12-04 WO PCT/IB2006/003549 patent/WO2007069020A2/en not_active Ceased