JP2024532768A5 - - Google Patents
Info
- Publication number
- JP2024532768A5 JP2024532768A5 JP2024508407A JP2024508407A JP2024532768A5 JP 2024532768 A5 JP2024532768 A5 JP 2024532768A5 JP 2024508407 A JP2024508407 A JP 2024508407A JP 2024508407 A JP2024508407 A JP 2024508407A JP 2024532768 A5 JP2024532768 A5 JP 2024532768A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- pharmaceutically acceptable
- stereoisomer
- acceptable salt
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110955364.5 | 2021-08-19 | ||
| CN202110955364 | 2021-08-19 | ||
| CN202111515247 | 2021-12-13 | ||
| CN202111515247.3 | 2021-12-13 | ||
| CN202210515797.3 | 2022-05-12 | ||
| CN202210515797 | 2022-05-12 | ||
| PCT/CN2022/113499 WO2023020605A1 (zh) | 2021-08-19 | 2022-08-19 | 喜树碱衍生物、其药物组合物及其应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024532768A JP2024532768A (ja) | 2024-09-10 |
| JP2024532768A5 true JP2024532768A5 (https=) | 2025-08-27 |
Family
ID=85239565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024508407A Pending JP2024532768A (ja) | 2021-08-19 | 2022-08-19 | カンプトテシン誘導体、その薬物組成物およびその応用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250270227A1 (https=) |
| EP (1) | EP4389752A4 (https=) |
| JP (1) | JP2024532768A (https=) |
| KR (1) | KR20240049583A (https=) |
| CN (1) | CN117769555A (https=) |
| AU (1) | AU2022330892A1 (https=) |
| CA (1) | CA3228345A1 (https=) |
| WO (1) | WO2023020605A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112023018676A2 (pt) | 2021-03-18 | 2023-10-10 | Seagen Inc | Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco |
| WO2023178289A2 (en) * | 2022-03-17 | 2023-09-21 | Seagen Inc. | Camptothecin conjugates |
| JP2025515988A (ja) * | 2022-05-13 | 2025-05-23 | シチュアン ケルン－バイオテック バイオファーマシューティカル カンパニー リミテッド | カンプトテシン化合物、その調製方法及びその使用 |
| CN119630672B (zh) * | 2023-02-23 | 2026-01-30 | 一线医药（杭州）有限公司 | 喜树碱衍生物及其偶联物以及其制备方法和医药用途 |
| KR20240149823A (ko) * | 2023-04-06 | 2024-10-15 | 주식회사 피노바이오 | 항암 내성 극복을 위한 신규 캄토테신 유도체 및 이를 포함하는 항체-약물 접합체 |
| CN120858098A (zh) * | 2023-05-04 | 2025-10-28 | 四川科伦博泰生物医药股份有限公司 | 稠环化合物及其制备方法和应用 |
| WO2024227439A1 (zh) * | 2023-05-04 | 2024-11-07 | 四川科伦博泰生物医药股份有限公司 | 具有靶向作用的偶联物及其制备方法和用途 |
| WO2025153001A1 (zh) * | 2024-01-17 | 2025-07-24 | 北京泰德制药股份有限公司 | 含有噻唑[5,4-b]吡啶结构的抗体偶联药物及其用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0540099B1 (en) * | 1991-10-29 | 1996-04-17 | Glaxo Wellcome Inc. | Water soluble camptothecin derivatives |
| CN1036197C (zh) * | 1992-01-28 | 1997-10-22 | 格拉克索有限公司 | 水溶性喜树碱衍生物 |
| JPH1171280A (ja) * | 1997-06-26 | 1999-03-16 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
| BR112020020466A2 (pt) * | 2018-04-06 | 2021-01-12 | Seattle Genetics, Inc. | Conjugados de peptídeo de camptotecina |
| TWI851577B (zh) * | 2018-06-07 | 2024-08-11 | 美商思進公司 | 喜樹鹼結合物 |
| SG11202110922QA (en) | 2019-04-26 | 2021-10-28 | Immunogen Inc | Camptothecin derivatives |
| EP4628165A3 (en) * | 2021-02-05 | 2026-03-11 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Camptothecin compound, preparation method therefor, and application thereof |
| EP4257154A4 (en) * | 2021-02-09 | 2026-04-22 | Medilink Therapeutics Suzhou Co Ltd | CONJUGATED WITH A BIOACTIVE SUBSTANCE, ITS PREPARATION PROCESS AND ITS USE |
| IL308734A (en) * | 2021-05-27 | 2024-01-01 | Zymeworks Bc Inc | Camptothecin analogues, conjugates and methods of use |
| US20240376120A1 (en) * | 2021-09-01 | 2024-11-14 | Shanghai Best-Link Bioscience, Llc | Camptothecin compound, preparation method therefor and use thereof |
| WO2023178289A2 (en) * | 2022-03-17 | 2023-09-21 | Seagen Inc. | Camptothecin conjugates |
| JP2025515988A (ja) * | 2022-05-13 | 2025-05-23 | シチュアン ケルン－バイオテック バイオファーマシューティカル カンパニー リミテッド | カンプトテシン化合物、その調製方法及びその使用 |
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2022
- 2022-08-19 JP JP2024508407A patent/JP2024532768A/ja active Pending
- 2022-08-19 WO PCT/CN2022/113499 patent/WO2023020605A1/zh not_active Ceased
- 2022-08-19 EP EP22857914.0A patent/EP4389752A4/en active Pending
- 2022-08-19 CN CN202280054490.6A patent/CN117769555A/zh active Pending
- 2022-08-19 KR KR1020247009078A patent/KR20240049583A/ko active Pending
- 2022-08-19 CA CA3228345A patent/CA3228345A1/en active Pending
- 2022-08-19 US US18/684,477 patent/US20250270227A1/en active Pending
- 2022-08-19 AU AU2022330892A patent/AU2022330892A1/en active Pending