JP5960055B2 - 改変髄膜炎菌fHBPポリペプチド - Google Patents

改変髄膜炎菌fHBPポリペプチド Download PDF

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Publication number
JP5960055B2
JP5960055B2 JP2012535995A JP2012535995A JP5960055B2 JP 5960055 B2 JP5960055 B2 JP 5960055B2 JP 2012535995 A JP2012535995 A JP 2012535995A JP 2012535995 A JP2012535995 A JP 2012535995A JP 5960055 B2 JP5960055 B2 JP 5960055B2
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amino acid
seq
polypeptide
fhbp
acid sequence
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JP2014503172A (ja
JP2014503172A5 (https=
Inventor
ルチア バンチ,
ルチア バンチ,
フランチェスカ カンティーニ,
フランチェスカ カンティーニ,
サラ ドラゴネッティ,
サラ ドラゴネッティ,
マリア アントニエッタ ジェンティレ,
マリア アントニエッタ ジェンティレ,
ダニエレ ベッジ,
ダニエレ ベッジ,
マリア スカーセッリ,
マリア スカーセッリ,
ピッツァ, マリアグラツィア
マリアグラツィア ピッツァ,
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ノバルティス アーゲー
ノバルティス アーゲー
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012535995A 2009-10-27 2010-10-27 改変髄膜炎菌fHBPポリペプチド Expired - Fee Related JP5960055B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27997709P 2009-10-27 2009-10-27
US61/279,977 2009-10-27
PCT/IB2010/054865 WO2011051893A1 (en) 2009-10-27 2010-10-27 Modified meningococcal fhbp polypeptides

Related Child Applications (1)

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JP2015205429A Division JP2016040302A (ja) 2009-10-27 2015-10-19 改変髄膜炎菌fHBPポリペプチド

Publications (3)

Publication Number Publication Date
JP2014503172A JP2014503172A (ja) 2014-02-13
JP2014503172A5 JP2014503172A5 (https=) 2014-04-03
JP5960055B2 true JP5960055B2 (ja) 2016-08-02

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JP2012535995A Expired - Fee Related JP5960055B2 (ja) 2009-10-27 2010-10-27 改変髄膜炎菌fHBPポリペプチド
JP2015205429A Pending JP2016040302A (ja) 2009-10-27 2015-10-19 改変髄膜炎菌fHBPポリペプチド

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US (2) US20130022633A1 (https=)
EP (1) EP2493499A1 (https=)
JP (2) JP5960055B2 (https=)
CN (1) CN102917730A (https=)
AU (1) AU2010310985B2 (https=)
BR (1) BR112012010531A2 (https=)
CA (1) CA2779816A1 (https=)
MX (1) MX2012004850A (https=)
WO (1) WO2011051893A1 (https=)

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EA201690056A8 (ru) 2013-08-02 2017-07-31 Чилдренс Хоспитл Энд Рисерч Сентер Эт Окленд ИСКУССТВЕННЫЕ БЕЛКИ, СВЯЗЫВАЮЩИЕ ФАКТОР Н (fHbp), И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
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JP6786394B2 (ja) 2014-02-28 2020-11-18 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 改変髄膜炎菌fHbpポリペプチド
KR102626831B1 (ko) 2014-07-17 2024-01-22 글락소스미스클라인 바이오로지칼즈 에스.에이. 수막구균 백신
AU2015289192A1 (en) * 2014-07-17 2017-02-02 Glaxosmithkline Biologicals S.A. Modified meningococcal fHbp polypeptides
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AU2016221318B2 (en) 2015-02-19 2020-06-25 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
KR102906912B1 (ko) 2016-09-02 2026-01-05 사노피 파스퇴르 인크 네이세리아 메닌기티디스 백신
EP3312192B1 (en) * 2016-10-24 2023-02-22 BiOMVis Srl Immunogenic compositions containing bacterial outer membrane vesicles
AU2018215585B2 (en) 2017-01-31 2022-03-17 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
EP4034157A1 (en) 2019-09-27 2022-08-03 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
US12053516B2 (en) 2021-02-19 2024-08-06 Sanofi Pasteur Inc. Meningococcal B recombinant vaccine
TW202423477A (zh) 2022-08-03 2024-06-16 美商賽諾菲巴斯德公司 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物
CN120241991B (zh) * 2025-06-05 2025-12-23 北京绿竹生物技术股份有限公司 一种新型的b群流脑外膜蛋白双功能载体

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AU2010310985A1 (en) 2012-05-24
MX2012004850A (es) 2012-05-22
JP2016040302A (ja) 2016-03-24
CN102917730A (zh) 2013-02-06
US20130022633A1 (en) 2013-01-24
WO2011051893A1 (en) 2011-05-05
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CA2779816A1 (en) 2011-05-05
AU2010310985B2 (en) 2014-11-06

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