JP5640153B2 - ダングリング親水性ポリマー鎖を有する連鎖延長ポリシロキサン架橋剤 - Google Patents
ダングリング親水性ポリマー鎖を有する連鎖延長ポリシロキサン架橋剤 Download PDFInfo
- Publication number
- JP5640153B2 JP5640153B2 JP2013532902A JP2013532902A JP5640153B2 JP 5640153 B2 JP5640153 B2 JP 5640153B2 JP 2013532902 A JP2013532902 A JP 2013532902A JP 2013532902 A JP2013532902 A JP 2013532902A JP 5640153 B2 JP5640153 B2 JP 5640153B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- polysiloxane
- acid
- vinyl
- meth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/38—Polysiloxanes modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
- C08G77/442—Block-or graft-polymers containing polysiloxane sequences containing vinyl polymer sequences
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
- C08G77/46—Block-or graft-polymers containing polysiloxane sequences containing polyether sequences
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
- C08L83/10—Block- or graft-copolymers containing polysiloxane sequences
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B2207/00—Coding scheme for general features or characteristics of optical elements and systems of subclass G02B, but not including elements and systems which would be classified in G02B6/00 and subgroups
- G02B2207/109—Sols, gels, sol-gel materials
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Eyeglasses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39046410P | 2010-10-06 | 2010-10-06 | |
| US61/390,464 | 2010-10-06 | ||
| US42267210P | 2010-12-14 | 2010-12-14 | |
| US61/422,672 | 2010-12-14 | ||
| PCT/US2011/054870 WO2012047964A1 (en) | 2010-10-06 | 2011-10-05 | Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013540188A JP2013540188A (ja) | 2013-10-31 |
| JP2013540188A5 JP2013540188A5 (enExample) | 2014-07-10 |
| JP5640153B2 true JP5640153B2 (ja) | 2014-12-10 |
Family
ID=45925625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532902A Active JP5640153B2 (ja) | 2010-10-06 | 2011-10-05 | ダングリング親水性ポリマー鎖を有する連鎖延長ポリシロキサン架橋剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8835525B2 (enExample) |
| EP (1) | EP2625217B1 (enExample) |
| JP (1) | JP5640153B2 (enExample) |
| BR (1) | BR112013008221B1 (enExample) |
| CA (1) | CA2811013C (enExample) |
| WO (1) | WO2012047964A1 (enExample) |
Families Citing this family (108)
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|---|---|---|---|---|
| BR112013008221B1 (pt) | 2010-10-06 | 2020-02-11 | Alcon Inc. | Pré-polímero processável em água, lente de contato de hidrogel de silicone e seu método de fabricação |
| SG188507A1 (en) * | 2010-10-06 | 2013-04-30 | Novartis Ag | Water-processable silicone-containing prepolymers and uses thereof |
| AU2013220367B2 (en) * | 2012-02-15 | 2016-06-09 | Dsm Ip Assets B.V. | Polysiloxane based block copolymers |
| JP6065988B2 (ja) | 2012-12-14 | 2017-01-25 | ノバルティス アーゲー | トリス(トリメチルシロキシ)シランビニル系モノマー及びその用途 |
| JP6154022B2 (ja) | 2012-12-14 | 2017-06-28 | ノバルティス アーゲー | 両親媒性シロキサン含有(メタ)アクリルアミド及びこれらの使用 |
| WO2014093756A1 (en) | 2012-12-14 | 2014-06-19 | Novartis Ag | Actinically-crosslinkable amphiphilic prepolymers |
| EP2931732B1 (en) | 2012-12-14 | 2020-11-25 | Alcon Inc. | Amphiphilic siloxane-containing vinylic monomers and uses thereof |
| US9486311B2 (en) | 2013-02-14 | 2016-11-08 | Shifamed Holdings, Llc | Hydrophilic AIOL with bonding |
| WO2014152017A1 (en) | 2013-03-21 | 2014-09-25 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| US10195018B2 (en) | 2013-03-21 | 2019-02-05 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| SG2013035662A (en) * | 2013-05-08 | 2014-12-30 | Menicon Singapore Pte Ltd | Systems and methods for printing on a contact lens |
| EP2808707A1 (en) | 2013-05-31 | 2014-12-03 | DSM IP Assets B.V. | Macromers comprising pendant polyoxazoline groups |
| SG11201601187VA (en) | 2013-09-30 | 2016-04-28 | Novartis Ag | Method for making uv-absorbing ophthalmic lenses |
| US9568645B2 (en) | 2013-09-30 | 2017-02-14 | Novartis Ag | Silicone hydrogel lenses with relatively-long thermal stability |
| CN105658391B (zh) | 2013-10-31 | 2019-02-19 | 诺华股份有限公司 | 生产眼用透镜的方法 |
| HUE036795T2 (hu) | 2013-12-13 | 2018-07-30 | Novartis Ag | Eljárás kontaktlencse elõállítására |
| WO2015164630A1 (en) | 2014-04-25 | 2015-10-29 | Novartis Ag | Carbosiloxane vinylic monomers |
| CA2940207C (en) | 2014-04-25 | 2019-09-10 | Novartis Ag | Hydrophilized carbosiloxane vinylic monomers |
| US10174233B2 (en) * | 2014-07-02 | 2019-01-08 | The Yokohama Rubber Co., Ltd. | Reactive hot-melt adhesive composition |
| CN107106293B (zh) | 2014-08-26 | 2019-07-12 | 施菲姆德控股有限责任公司 | 调节性人工晶状体 |
| NZ728772A (en) | 2014-09-26 | 2018-10-26 | Novartis Ag | Polymerizable polysiloxanes with hydrophilic substituents |
| EP3268804B1 (en) | 2015-03-11 | 2020-11-04 | University of Florida Research Foundation, Inc. | Mesh size control of lubrication in gemini hydrogels |
| US10266445B2 (en) | 2015-05-07 | 2019-04-23 | Novartis Ag | Method for producing contact lenses with durable lubricious coatings thereon |
| CA2992823C (en) | 2015-09-04 | 2019-10-29 | Novartis Ag | Method for producing contact lenses with durable lubricious coatings thereon |
| JP6680870B2 (ja) | 2015-09-04 | 2020-04-15 | アルコン インク. | その上に耐久性潤滑性コーティングを有するソフトシリコーン医療デバイス |
| US11141263B2 (en) | 2015-11-18 | 2021-10-12 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lens |
| AU2016358160B2 (en) | 2015-11-18 | 2021-07-29 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lens |
| JP6708737B2 (ja) | 2015-12-15 | 2020-06-10 | アルコン インク. | 親水性置換基を有する重合性ポリシロキサン |
| JP6615349B2 (ja) * | 2015-12-15 | 2019-12-04 | ノバルティス アーゲー | 両親媒性分枝鎖状ポリジオルガノシロキサンマクロマー |
| US10081142B2 (en) | 2015-12-15 | 2018-09-25 | Novartis Ag | Method for producing contact lenses with a lubricious surface |
| MY197430A (en) * | 2015-12-15 | 2023-06-17 | Alcon Inc | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof |
| WO2017145023A1 (en) * | 2016-02-22 | 2017-08-31 | Novartis Ag | Soft silicone medical devices |
| US10254567B2 (en) | 2016-02-22 | 2019-04-09 | Novartis Ag | UV-absorbing vinylic monomers and uses thereof |
| EP3419961B1 (en) | 2016-02-22 | 2020-09-02 | Alcon Inc. | Uv/visible-absorbing vinylic monomers and uses thereof |
| WO2018055491A1 (en) | 2016-09-20 | 2018-03-29 | Novartis Ag | Process for producing contact lenses with durable lubricious coatings thereon |
| US10301451B2 (en) | 2016-10-11 | 2019-05-28 | Novartis Ag | Chain-extended polydimethylsiloxane vinylic crosslinkers and uses thereof |
| JP6839295B2 (ja) | 2016-10-11 | 2021-03-03 | アルコン インク. | 重合性ポリジメチルシロキサン−ポリオキシアルキレンブロックコポリマー |
| JP6965703B2 (ja) * | 2016-11-28 | 2021-11-10 | 東洋インキScホールディングス株式会社 | (メタ)アクリル系重合体、(メタ)アクリル系ブロック共重合体、顔料分散体、感光性着色組成物、カラーフィルタ、インキ組成物、複合ブロック共重合体、顔料分散剤。 |
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2011
- 2011-10-05 BR BR112013008221-6A patent/BR112013008221B1/pt active IP Right Grant
- 2011-10-05 EP EP11770628.3A patent/EP2625217B1/en active Active
- 2011-10-05 CA CA2811013A patent/CA2811013C/en active Active
- 2011-10-05 JP JP2013532902A patent/JP5640153B2/ja active Active
- 2011-10-05 US US13/253,177 patent/US8835525B2/en active Active
- 2011-10-05 WO PCT/US2011/054870 patent/WO2012047964A1/en not_active Ceased
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Also Published As
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|---|---|
| US20140350124A1 (en) | 2014-11-27 |
| US8835525B2 (en) | 2014-09-16 |
| US9052440B2 (en) | 2015-06-09 |
| JP2013540188A (ja) | 2013-10-31 |
| EP2625217A1 (en) | 2013-08-14 |
| EP2625217B1 (en) | 2018-07-04 |
| US20120088844A1 (en) | 2012-04-12 |
| CA2811013A1 (en) | 2012-04-12 |
| BR112013008221A2 (pt) | 2016-06-21 |
| BR112013008221B1 (pt) | 2020-02-11 |
| WO2012047964A1 (en) | 2012-04-12 |
| CA2811013C (en) | 2016-01-19 |
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