BR112013008221A2 - pré-polímeros contendo silicone processáveis em água e usos dos mesmos - Google Patents

pré-polímeros contendo silicone processáveis em água e usos dos mesmos

Info

Publication number
BR112013008221A2
BR112013008221A2 BR112013008221A BR112013008221A BR112013008221A2 BR 112013008221 A2 BR112013008221 A2 BR 112013008221A2 BR 112013008221 A BR112013008221 A BR 112013008221A BR 112013008221 A BR112013008221 A BR 112013008221A BR 112013008221 A2 BR112013008221 A2 BR 112013008221A2
Authority
BR
Brazil
Prior art keywords
water
weight
silicone
processable
polysiloxane
Prior art date
Application number
BR112013008221A
Other languages
English (en)
Other versions
BR112013008221B1 (pt
Inventor
Arturo Noberto Medina
Daqing Wu
Dawn Alison Smith
Frank Chang
Jinyu Huang
Manivakkan J Shankernarayanan
Robert Scott
Selma Kuyu
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority claimed from PCT/US2011/054878 external-priority patent/WO2012047969A1/en
Publication of BR112013008221A2 publication Critical patent/BR112013008221A2/pt
Publication of BR112013008221B1 publication Critical patent/BR112013008221B1/pt

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/38—Polysiloxanes modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C08G77/442—Block-or graft-polymers containing polysiloxane sequences containing vinyl polymer sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C08G77/46—Block-or graft-polymers containing polysiloxane sequences containing polyether sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/10—Block- or graft-copolymers containing polysiloxane sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B2207/00—Coding scheme for general features or characteristics of optical elements and systems of subclass G02B, but not including elements and systems which would be classified in G02B6/00 and subgroups
    • G02B2207/109—Sols, gels, sol-gel materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Eyeglasses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

pré-polímeros contendo silicone processáveis em água e usos dos mesmos. a presente invenção refere-se a uma classe de pré-polímeros polimerizáveis processáveis em água compreendendo (1) unidades monoméricas contendo siloxano derivadas pelo menos um monômero contendo siloxano tendo um grupo hidrófilo ou unidades de cadeia e/ou de reticulação contendo polissiloxa derivadas de pelo menos um polissiloxano hidrolizado ou reticulador de polissiloxano de cadeia estendida; (2) unidades monoméricas hidrófilas derivadas de um ou mais monômeros vinílicos hidrófilos; e (3) de cerca de 0,05% a cerca 5% em peso de unidades polimerizaveis cada tendo um grupo pendente ou terminal etilenicamente insaturado e livre de qualquer segmento de polissiloxano. o pré-polímero compreende de cerca de 20% a cerca de 50% em peso de silicone com relação ao peso total do pré-polímero e tem uma solubilidade ou dispersabilidade em água alta de pelo menos cerca de 5% em peso em água e adequado para fazer lentes de contato de hidrogel de silicone
BR112013008221-6A 2010-10-06 2011-10-05 Pré-polímero processável em água, lente de contato de hidrogel de silicone e seu método de fabricação BR112013008221B1 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US39044810P 2010-10-06 2010-10-06
US39046410P 2010-10-06 2010-10-06
US61/390,448 2010-10-06
US61/390,464 2010-10-06
US42267210P 2010-12-14 2010-12-14
US61/422,672 2010-12-14
PCT/US2011/054878 WO2012047969A1 (en) 2010-10-06 2011-10-05 Water-processable silicone-containing prepolymers and uses thereof

Publications (2)

Publication Number Publication Date
BR112013008221A2 true BR112013008221A2 (pt) 2016-06-21
BR112013008221B1 BR112013008221B1 (pt) 2020-02-11

Family

ID=45925625

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013008221-6A BR112013008221B1 (pt) 2010-10-06 2011-10-05 Pré-polímero processável em água, lente de contato de hidrogel de silicone e seu método de fabricação

Country Status (6)

Country Link
US (2) US8835525B2 (pt)
EP (1) EP2625217B1 (pt)
JP (1) JP5640153B2 (pt)
BR (1) BR112013008221B1 (pt)
CA (1) CA2811013C (pt)
WO (1) WO2012047964A1 (pt)

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