JP5536995B2 - 顕微鏡対物レンズおよびレーザー走査型顕微鏡システム - Google Patents
顕微鏡対物レンズおよびレーザー走査型顕微鏡システム Download PDFInfo
- Publication number
- JP5536995B2 JP5536995B2 JP2008179449A JP2008179449A JP5536995B2 JP 5536995 B2 JP5536995 B2 JP 5536995B2 JP 2008179449 A JP2008179449 A JP 2008179449A JP 2008179449 A JP2008179449 A JP 2008179449A JP 5536995 B2 JP5536995 B2 JP 5536995B2
- Authority
- JP
- Japan
- Prior art keywords
- lens
- lens group
- objective lens
- microscope objective
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B15/00—Optical objectives with means for varying the magnification
- G02B15/14—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective
- G02B15/145—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having five groups only
- G02B15/1451—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having five groups only the first group being positive
- G02B15/145119—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having five groups only the first group being positive arranged ++--+
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/02—Objectives
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/33—Immersion oils, or microscope systems or objectives for use with immersion fluids
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B9/00—Optical objectives characterised both by the number of the components and their arrangements according to their sign, i.e. + or -
- G02B9/60—Optical objectives characterised both by the number of the components and their arrangements according to their sign, i.e. + or - having five components only
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Lenses (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008179449A JP5536995B2 (ja) | 2007-07-17 | 2008-07-09 | 顕微鏡対物レンズおよびレーザー走査型顕微鏡システム |
| US12/173,111 US7869132B2 (en) | 2007-07-17 | 2008-07-15 | Immersion microscope objective and laser scanning microscope system using same |
| EP12008380.3A EP2573608B1 (en) | 2007-07-17 | 2008-07-16 | Immersion microscope objective and laser scanning microscope system using the same |
| EP08012853.1A EP2017663B1 (en) | 2007-07-17 | 2008-07-16 | Immersion microscope objective and laser scanning microscope system using the same |
| EP12008381.1A EP2573609B1 (en) | 2007-07-17 | 2008-07-16 | Immersion microscope objective and laser scanning microscope system using the same |
| US12/916,240 US8576482B2 (en) | 2007-07-17 | 2010-10-29 | Laser scanning microscope system |
| US12/916,188 US8508856B2 (en) | 2007-07-17 | 2010-10-29 | Immersion microscope objective and laser scanning microscope system using same |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007186369 | 2007-07-17 | ||
| JP2007186369 | 2007-07-17 | ||
| JP2008138231 | 2008-05-27 | ||
| JP2008138231 | 2008-05-27 | ||
| JP2008179449A JP5536995B2 (ja) | 2007-07-17 | 2008-07-09 | 顕微鏡対物レンズおよびレーザー走査型顕微鏡システム |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013061512A Division JP5596810B2 (ja) | 2007-07-17 | 2013-03-25 | 液浸系顕微鏡対物レンズ、及び、レーザー走査型顕微鏡システム |
| JP2013061511A Division JP2013152484A (ja) | 2007-07-17 | 2013-03-25 | レーザー走査型顕微鏡システム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010008989A JP2010008989A (ja) | 2010-01-14 |
| JP2010008989A5 JP2010008989A5 (https=) | 2011-08-11 |
| JP5536995B2 true JP5536995B2 (ja) | 2014-07-02 |
Family
ID=39967889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008179449A Active JP5536995B2 (ja) | 2007-07-17 | 2008-07-09 | 顕微鏡対物レンズおよびレーザー走査型顕微鏡システム |
Country Status (3)
| Country | Link |
|---|---|
| US (3) | US7869132B2 (https=) |
| EP (3) | EP2017663B1 (https=) |
| JP (1) | JP5536995B2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9709790B2 (en) | 2013-10-17 | 2017-07-18 | Olympus Corporation | Immersion microscope objective and microscope using the same |
| CN115903202A (zh) * | 2022-11-25 | 2023-04-04 | 沈阳国科光明医疗科技有限公司 | 高通量显微镜物镜 |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5309867B2 (ja) * | 2008-10-14 | 2013-10-09 | 株式会社ニコン | 非線形光学顕微鏡及びその調整方法 |
| WO2011059833A2 (en) * | 2009-10-29 | 2011-05-19 | California Institute Of Technology | Dual-mode raster point scanning/light sheet illumination microscope |
| US8634131B2 (en) * | 2009-12-14 | 2014-01-21 | Intelligent Imaging Innovations, Inc. | Spherical aberration correction for non-descanned applications |
| WO2012002542A1 (ja) * | 2010-07-01 | 2012-01-05 | 株式会社ニコン | 光学部材および顕微鏡 |
| WO2012027542A2 (en) | 2010-08-25 | 2012-03-01 | California Institute Of Technology | Simultaneous orthogonal light sheet microscopy and computed optical tomography |
| JP5926914B2 (ja) * | 2010-11-10 | 2016-05-25 | オリンパス株式会社 | 液浸顕微鏡対物レンズ |
| JP5730671B2 (ja) * | 2011-05-31 | 2015-06-10 | オリンパス株式会社 | ズーム結像光学系、及び、それを備えた顕微鏡 |
| JP5839897B2 (ja) * | 2011-09-02 | 2016-01-06 | オリンパス株式会社 | 非線形光学顕微鏡 |
| JP5885537B2 (ja) * | 2012-02-28 | 2016-03-15 | オリンパス株式会社 | 顕微鏡対物レンズ |
| JP5988629B2 (ja) * | 2012-03-14 | 2016-09-07 | オリンパス株式会社 | 複数の光学ユニットを備えた顕微鏡 |
| JPWO2013145836A1 (ja) * | 2012-03-30 | 2015-12-10 | ソニー株式会社 | マイクロチップ型光学測定装置及び該装置における光学位置調整方法 |
| WO2014014805A1 (en) * | 2012-07-16 | 2014-01-23 | Trustees Of Boston University | Solid immersion microscopy system with deformable mirror for correction of aberrations |
| JP5993250B2 (ja) * | 2012-08-29 | 2016-09-14 | オリンパス株式会社 | 液浸顕微鏡対物レンズ及びそれを用いた顕微鏡 |
| JP6274952B2 (ja) | 2013-04-24 | 2018-02-07 | オリンパス株式会社 | 液浸顕微鏡対物レンズ及びそれを用いた顕微鏡 |
| JP6377319B2 (ja) * | 2013-05-24 | 2018-08-22 | 株式会社タムロン | ズームレンズ及び撮像装置 |
| JP2015045773A (ja) * | 2013-08-29 | 2015-03-12 | 富士フイルム株式会社 | 走査光学系、光走査装置および放射線画像読取装置 |
| JP6223115B2 (ja) * | 2013-10-18 | 2017-11-01 | オリンパス株式会社 | 液浸顕微鏡対物レンズ及びそれを用いた顕微鏡 |
| EP3087423B1 (en) * | 2013-12-24 | 2025-12-10 | Tissuevision, Inc. | Multi-foci multiphoton imaging systems and methods |
| CN105445824B (zh) * | 2014-08-20 | 2017-02-22 | 清华大学 | Led光通信接收透镜及led光通信系统 |
| CN107076966B (zh) * | 2014-09-29 | 2022-05-24 | Asml控股股份有限公司 | 高数值孔径物镜系统 |
| US10018817B2 (en) * | 2015-03-04 | 2018-07-10 | Aramco Services Company | Adaptive optics for imaging through highly scattering media in oil reservoir applications |
| EP3268715B1 (en) | 2015-03-11 | 2024-09-25 | TissueVision, Inc. | System and methods for serial staining and imaging |
| EP3387481B1 (en) * | 2015-12-07 | 2024-09-25 | ASML Holding N.V. | Objective lens system |
| DE202016008115U1 (de) * | 2016-07-01 | 2017-03-01 | Carl Zeiss Ag | Anordnung zur Mikroskopie und zur Korrektur von Aberrationen |
| JP2018066912A (ja) | 2016-10-20 | 2018-04-26 | オリンパス株式会社 | 対物レンズ |
| JP6906923B2 (ja) | 2016-10-20 | 2021-07-21 | オリンパス株式会社 | 液浸系対物レンズ |
| JP7197477B2 (ja) | 2016-11-18 | 2022-12-27 | ティシュヴィジョン、インコーポレーテッド | 自動化された組織切片の捕捉、指標付けおよび保管システム |
| DE102017108595B3 (de) * | 2017-04-21 | 2018-05-09 | Leica Microsystems Cms Gmbh | Immersionsobjektiv für ein Mikroskop |
| DE102017108593B4 (de) * | 2017-04-21 | 2019-03-14 | Leica Microsystems Cms Gmbh | Korrektionsobjektiv für ein Mikroskop, Immersionsobjektiv und Mikroskop |
| DE102017208615A1 (de) | 2017-05-22 | 2018-11-22 | Carl Zeiss Microscopy Gmbh | Verfahren und Adapter zur Adaption eines Mikroskopobjektivs an ein Digitalmikroskop |
| CN112105287B (zh) | 2018-03-30 | 2023-09-01 | 株式会社尼康 | 眼科装置及眼科光学系统 |
| JP2019191273A (ja) * | 2018-04-19 | 2019-10-31 | オリンパス株式会社 | 対物レンズ |
| JP2019191272A (ja) | 2018-04-19 | 2019-10-31 | オリンパス株式会社 | 液浸系の顕微鏡対物レンズ |
| JP2019191274A (ja) * | 2018-04-19 | 2019-10-31 | オリンパス株式会社 | 撮像光学系、及び、顕微鏡システム |
| DE102019204285A1 (de) | 2019-03-27 | 2020-10-01 | Carl Zeiss Microscopy Gmbh | Objektiv für ein Mikroskop |
| CN110262025B (zh) * | 2019-07-01 | 2024-07-02 | 达科为(深圳)医疗设备有限公司 | 一种数字化病理成像设备 |
| DE102020108333B3 (de) | 2020-03-26 | 2021-07-15 | Technische Universität Ilmenau | Verfahren und Vorrichtung zur Kompensation von instationären Aberrationen bei der konfokalen Vermessung einer Probenoberfläche |
| EP3936922B1 (en) * | 2020-07-10 | 2022-12-21 | Leica Microsystems CMS GmbH | Immersion microscope and method for generating an overview image of a sample |
| CN113376810B (zh) * | 2021-06-29 | 2025-03-18 | 江西欧菲光学有限公司 | 光学系统、取像模组及电子设备 |
| WO2023002788A1 (ja) * | 2021-07-21 | 2023-01-26 | ソニーグループ株式会社 | 対物レンズ及び試料分析装置 |
| CN114185151B (zh) * | 2021-12-01 | 2024-04-30 | 苏州中科全象智能科技有限公司 | 一种具有长入瞳距的双波段像方远心扫描物镜 |
| CN115452783B (zh) * | 2022-08-22 | 2023-12-22 | 深圳赛陆医疗科技有限公司 | 检测装置及基因测序仪 |
| CN121254476A (zh) * | 2022-08-26 | 2026-01-02 | 深圳市中图仪器股份有限公司 | 共聚焦显微镜的光学系统 |
| CN119395857B (zh) * | 2024-12-16 | 2025-12-09 | 南阳南方智能光电有限公司 | 基于lcos的小画幅尺寸投射镜头及投影仪 |
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| US3700311A (en) | 1971-11-22 | 1972-10-24 | American Optical Corp | Eight component 100x microscope objective |
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| JPH06160720A (ja) * | 1992-11-20 | 1994-06-07 | Olympus Optical Co Ltd | 液浸系顕微鏡対物レンズ |
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| JP2005043624A (ja) | 2003-07-28 | 2005-02-17 | Nikon Corp | 顕微鏡制御装置、顕微鏡装置、及び顕微鏡対物レンズ |
| JP2005099131A (ja) | 2003-09-22 | 2005-04-14 | Olympus Corp | 顕微鏡用対物レンズ |
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| JP4496524B2 (ja) * | 2004-03-17 | 2010-07-07 | 株式会社ニコン | 液浸系顕微鏡対物レンズ |
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| JP2008040154A (ja) | 2006-08-07 | 2008-02-21 | Olympus Corp | 共焦点レーザ顕微鏡 |
| JP5112832B2 (ja) * | 2006-12-11 | 2013-01-09 | オリンパス株式会社 | 顕微鏡対物レンズ及びそれを用いた蛍光観察装置 |
| JP4994826B2 (ja) * | 2006-12-25 | 2012-08-08 | オリンパス株式会社 | レーザ顕微鏡 |
| US20090174935A1 (en) * | 2008-01-09 | 2009-07-09 | Szulczewski Michael J | Scanning microscope having complementary, serial scanners |
-
2008
- 2008-07-09 JP JP2008179449A patent/JP5536995B2/ja active Active
- 2008-07-15 US US12/173,111 patent/US7869132B2/en active Active
- 2008-07-16 EP EP08012853.1A patent/EP2017663B1/en not_active Revoked
- 2008-07-16 EP EP12008380.3A patent/EP2573608B1/en active Active
- 2008-07-16 EP EP12008381.1A patent/EP2573609B1/en not_active Revoked
-
2010
- 2010-10-29 US US12/916,240 patent/US8576482B2/en active Active
- 2010-10-29 US US12/916,188 patent/US8508856B2/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9709790B2 (en) | 2013-10-17 | 2017-07-18 | Olympus Corporation | Immersion microscope objective and microscope using the same |
| CN115903202A (zh) * | 2022-11-25 | 2023-04-04 | 沈阳国科光明医疗科技有限公司 | 高通量显微镜物镜 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2573608A3 (en) | 2013-04-17 |
| EP2573609A2 (en) | 2013-03-27 |
| JP2010008989A (ja) | 2010-01-14 |
| US20110043924A1 (en) | 2011-02-24 |
| EP2573609A3 (en) | 2013-04-17 |
| EP2573609B1 (en) | 2017-02-01 |
| EP2573608B1 (en) | 2017-08-30 |
| EP2017663A2 (en) | 2009-01-21 |
| US8508856B2 (en) | 2013-08-13 |
| US20090027769A1 (en) | 2009-01-29 |
| EP2017663A3 (en) | 2012-07-11 |
| US8576482B2 (en) | 2013-11-05 |
| US20110043906A1 (en) | 2011-02-24 |
| EP2573608A2 (en) | 2013-03-27 |
| US7869132B2 (en) | 2011-01-11 |
| EP2017663B1 (en) | 2014-10-01 |
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