JP4436319B2 - 単鎖組換えt細胞レセプター - Google Patents

単鎖組換えt細胞レセプター Download PDF

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Publication number
JP4436319B2
JP4436319B2 JP2005500992A JP2005500992A JP4436319B2 JP 4436319 B2 JP4436319 B2 JP 4436319B2 JP 2005500992 A JP2005500992 A JP 2005500992A JP 2005500992 A JP2005500992 A JP 2005500992A JP 4436319 B2 JP4436319 B2 JP 4436319B2
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tcr
chain
exon
sctcr
sequence
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JP2005500992A
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Japanese (ja)
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JP2006502741A (ja
JP2006502741A5 (https=
Inventor
ヤコブセン,ベント,カルステン
グリック,マイアー
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Medigene Ltd
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Medigene Ltd
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Priority claimed from GB0223399A external-priority patent/GB0223399D0/en
Priority claimed from GB0302604A external-priority patent/GB0302604D0/en
Priority claimed from GB0304064A external-priority patent/GB0304064D0/en
Application filed by Medigene Ltd filed Critical Medigene Ltd
Publication of JP2006502741A publication Critical patent/JP2006502741A/ja
Publication of JP2006502741A5 publication Critical patent/JP2006502741A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2005500992A 2002-10-09 2003-10-03 単鎖組換えt細胞レセプター Expired - Fee Related JP4436319B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0223399A GB0223399D0 (en) 2002-10-09 2002-10-09 Receptors
GB0302604A GB0302604D0 (en) 2003-02-05 2003-02-05 Receptors
GB0304064A GB0304064D0 (en) 2003-02-22 2003-02-22 Receptors
US47578403P 2003-06-05 2003-06-05
PCT/GB2003/004310 WO2004033685A1 (en) 2002-10-09 2003-10-03 Single chain recombinant t cell receptors

Publications (3)

Publication Number Publication Date
JP2006502741A JP2006502741A (ja) 2006-01-26
JP2006502741A5 JP2006502741A5 (https=) 2006-11-16
JP4436319B2 true JP4436319B2 (ja) 2010-03-24

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JP2005500992A Expired - Fee Related JP4436319B2 (ja) 2002-10-09 2003-10-03 単鎖組換えt細胞レセプター

Country Status (9)

Country Link
US (1) US7569664B2 (https=)
EP (1) EP1549748B1 (https=)
JP (1) JP4436319B2 (https=)
AU (1) AU2003271904B2 (https=)
CA (1) CA2501870C (https=)
IL (1) IL167652A (https=)
NO (1) NO335365B1 (https=)
NZ (1) NZ539225A (https=)
WO (1) WO2004033685A1 (https=)

Families Citing this family (359)

* Cited by examiner, † Cited by third party
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