GB0908613D0 - T Cell Reseptors - Google Patents
T Cell ReseptorsInfo
- Publication number
- GB0908613D0 GB0908613D0 GBGB0908613.3A GB0908613A GB0908613D0 GB 0908613 D0 GB0908613 D0 GB 0908613D0 GB 0908613 A GB0908613 A GB 0908613A GB 0908613 D0 GB0908613 D0 GB 0908613D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- reseptors
- cell
- cell reseptors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001136—Cytokines
- A61K39/00114—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (54)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0908613.3A GB0908613D0 (en) | 2009-05-20 | 2009-05-20 | T Cell Reseptors |
| EP16176249.7A EP3112377B1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| SM20170067T SMT201700067T1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| PL10720803T PL2432802T3 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| DK16176246.3T DK3112376T3 (en) | 2009-05-20 | 2010-05-19 | BIFUNCTIONAL POLYPEPTIDES |
| CA2968393A CA2968393C (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| EA201101660A EA020841B1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| DK16176249.7T DK3112377T3 (en) | 2009-05-20 | 2010-05-19 | BIFUNCTIONAL POLYPEPTIDES |
| PT161762497T PT3112377T (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| BRPI1013029A BRPI1013029A2 (en) | 2009-05-20 | 2010-05-19 | bifunctional polypeptides |
| JP2012511333A JP5667171B2 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptide |
| SM20190232T SMT201900232T1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| EP10720803.5A EP2432802B1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| TR2018/09945T TR201809945T4 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides. |
| MX2011012184A MX340168B (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides. |
| EP16176246.3A EP3112376B1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| LTEP10720803.5T LT2432802T (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| PT16176246T PT3112376T (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| HRP20170086TT HRP20170086T1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| SI201031358A SI2432802T1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| SI201031697T SI3112377T1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| CN201080022523.6A CN102439034B (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| PL16176249T PL3112377T3 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| TR2019/05437T TR201905437T4 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides. |
| AU2010250951A AU2010250951B2 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| PT107208035T PT2432802T (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| SM20180364T SMT201800364T1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| PCT/GB2010/000988 WO2010133828A1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| ES10720803.5T ES2608653T3 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| HUE16176246A HUE043245T2 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| HUE10720803A HUE032929T2 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| DK10720803.5T DK2432802T3 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| ES16176246T ES2721058T3 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| ES16176249.7T ES2672095T3 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| SI201031883T SI3112376T1 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| HUE16176249A HUE038342T2 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| CA2762604A CA2762604C (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| LTEP16176249.7T LT3112377T (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| US13/319,597 US10130721B2 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| PL16176246T PL3112376T3 (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| LTEP16176246.3T LT3112376T (en) | 2009-05-20 | 2010-05-19 | Bifunctional polypeptides |
| JP2014250885A JP2015096527A (en) | 2009-05-20 | 2014-12-11 | Bifunctional polypeptides |
| CY20161101365T CY1118405T1 (en) | 2009-05-20 | 2016-12-30 | BUSINESS INTERFACE polypeptides |
| JP2017009529A JP2017110019A (en) | 2009-05-20 | 2017-01-23 | Bifunctional polypeptide |
| CY20181100507T CY1120439T1 (en) | 2009-05-20 | 2018-05-04 | BUSINESS INTERFACE polypeptides |
| HRP20180757TT HRP20180757T1 (en) | 2009-05-20 | 2018-05-15 | Bifunctional polypeptides |
| US16/151,144 US20190247512A1 (en) | 2009-05-20 | 2018-10-03 | Bifunctional polypeptides |
| US16/378,505 US10420846B2 (en) | 2009-05-20 | 2019-04-08 | Bifunctional polypeptides |
| US16/378,501 US10576162B2 (en) | 2009-05-20 | 2019-04-08 | Bifunctional polypeptides |
| US16/378,481 US10517960B2 (en) | 2009-05-20 | 2019-04-08 | Bifunctional polypeptides |
| HRP20190674TT HRP20190674T1 (en) | 2009-05-20 | 2019-04-09 | Bifunctional polypeptides |
| CY20191100410T CY1121558T1 (en) | 2009-05-20 | 2019-04-12 | DIFFERENTIAL POLYPEPTIDES |
| JP2019088405A JP2019172678A (en) | 2009-05-20 | 2019-05-08 | Bifunctional polypeptides |
| US17/929,682 US20230241238A1 (en) | 2009-05-20 | 2022-09-02 | Bifunctional polypeptides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0908613.3A GB0908613D0 (en) | 2009-05-20 | 2009-05-20 | T Cell Reseptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0908613D0 true GB0908613D0 (en) | 2009-06-24 |
Family
ID=40834242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0908613.3A Ceased GB0908613D0 (en) | 2009-05-20 | 2009-05-20 | T Cell Reseptors |
Country Status (22)
| Country | Link |
|---|---|
| US (6) | US10130721B2 (en) |
| EP (3) | EP3112376B1 (en) |
| JP (4) | JP5667171B2 (en) |
| CN (1) | CN102439034B (en) |
| AU (1) | AU2010250951B2 (en) |
| BR (1) | BRPI1013029A2 (en) |
| CA (2) | CA2968393C (en) |
| CY (3) | CY1118405T1 (en) |
| DK (3) | DK3112377T3 (en) |
| EA (1) | EA020841B1 (en) |
| ES (3) | ES2672095T3 (en) |
| GB (1) | GB0908613D0 (en) |
| HR (3) | HRP20170086T1 (en) |
| HU (3) | HUE043245T2 (en) |
| LT (3) | LT3112377T (en) |
| MX (1) | MX340168B (en) |
| PL (3) | PL3112377T3 (en) |
| PT (3) | PT3112376T (en) |
| SI (3) | SI2432802T1 (en) |
| SM (3) | SMT201900232T1 (en) |
| TR (2) | TR201905437T4 (en) |
| WO (1) | WO2010133828A1 (en) |
Families Citing this family (107)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0908613D0 (en) | 2009-05-20 | 2009-06-24 | Immunocore Ltd | T Cell Reseptors |
| ES2989085T3 (en) | 2011-01-18 | 2024-11-25 | Bioniz Therapeutics Inc | Compositions to modulate gamma-c cytokine activity |
| ES2689512T3 (en) | 2011-09-15 | 2018-11-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cell receptors that recognize MAGE restricted by HLA-A1 or HLA-Cw7 |
| AU2012316859A1 (en) * | 2011-09-29 | 2014-04-17 | Apo-T B.V. | Multi-specific binding molecules targeting aberrant cells |
| AU2012332193A1 (en) | 2011-11-03 | 2014-05-15 | Tolera Therapeutics, Inc. | Antibody and methods for selective inhibition of T-cell responses |
| US20130273089A1 (en) | 2011-11-03 | 2013-10-17 | Tolera Therapeutics, Inc. | Antibody and methods for selective inhibition of t-cell responses |
| EP2802356A1 (en) | 2012-01-13 | 2014-11-19 | Apo-T B.V. | Aberrant cell-restricted immunoglobulins provided with a toxic moiety |
| GB201223172D0 (en) | 2012-12-21 | 2013-02-06 | Immunocore Ltd | Method |
| GB201313377D0 (en) * | 2013-07-26 | 2013-09-11 | Adaptimmune Ltd | T cell receptors |
| US9959384B2 (en) | 2013-12-10 | 2018-05-01 | Bioniz, Llc | Methods of developing selective peptide antagonists |
| EP3590958A1 (en) | 2014-03-14 | 2020-01-08 | Immunocore Limited | Tcr libraries |
| WO2016014725A1 (en) | 2014-07-22 | 2016-01-28 | The University Of Notre Dame Du Lac | Molecular constructs and uses thereof |
| WO2016070814A1 (en) | 2014-11-07 | 2016-05-12 | 广州市香雪制药股份有限公司 | Soluble heterodimeric t cell receptor, and preparation method and use thereof |
| GB201516269D0 (en) | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR Libraries |
| GB201516277D0 (en) | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR libraries |
| GB201516272D0 (en) | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR Libraries |
| GB201516265D0 (en) | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR Libraries |
| GB201516270D0 (en) | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR Libraries |
| GB201516274D0 (en) | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR Libraries |
| GB201516275D0 (en) | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR Libraries |
| HUE056544T2 (en) | 2015-10-09 | 2022-02-28 | Bioniz Llc | Modulation of gamma-C-cytokine activity |
| GB201607534D0 (en) | 2016-04-29 | 2016-06-15 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520539D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520550D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520536D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520566D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520548D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520567D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520597D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| WO2017089786A1 (en) | 2015-11-23 | 2017-06-01 | Immunocore Limited | Peptides |
| GB201520558D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520541D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520562D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520603D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201607535D0 (en) | 2016-04-29 | 2016-06-15 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520546D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520565D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201604468D0 (en) | 2016-03-16 | 2016-04-27 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520568D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd | Peptides |
| GB201520542D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520570D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520545D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520595D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520575D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520589D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520583D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520543D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520592D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520563D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520559D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520579D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520544D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520557D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520564D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201522592D0 (en) * | 2015-12-22 | 2016-02-03 | Immunocore Ltd | T cell receptors |
| PL3430037T3 (en) * | 2016-03-16 | 2022-12-19 | Immatics Biotechnologies Gmbh | Transfected t-cells and t-cell receptors for use in immunotherapy against cancers |
| GB201604953D0 (en) | 2016-03-23 | 2016-05-04 | Immunocore Ltd | T cell receptors |
| MX2018012318A (en) | 2016-04-08 | 2019-07-04 | Immunocore Ltd | T cell receptors. |
| WO2017192536A1 (en) | 2016-05-02 | 2017-11-09 | University Of Kansas | Eliminating mhc restriction from the t cell receptor as a strategy for immunotherapy |
| WO2017208018A1 (en) | 2016-06-02 | 2017-12-07 | Immunocore Limited | Dosing regimen for gp100-specific tcr - anti-cd3 scfv fusion protein |
| EP3532078A4 (en) * | 2016-10-31 | 2020-06-03 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | ARTIFICIAL ANTIGEN PRESENT CELLS USED FOR THE EXPANSION OF IMMUNE CELLS FOR IMMUNOTHERAPY |
| EP3535288A1 (en) | 2016-11-07 | 2019-09-11 | Immunocore Limited | Peptides |
| CN108203459A (en) * | 2016-12-19 | 2018-06-26 | 广东香雪精准医疗技术有限公司 | Tumour antigen small peptide from PRAME |
| GB201709866D0 (en) | 2017-06-20 | 2017-08-02 | Immunocore Ltd | T cell receptors |
| EP3794035A1 (en) | 2018-05-14 | 2021-03-24 | Immunocore Limited | Bifunctional binding polypeptides |
| GB201815041D0 (en) | 2018-09-14 | 2018-10-31 | Scancell Ltd | Epitopes |
| KR20210116478A (en) * | 2019-01-14 | 2021-09-27 | 난징 레전드 바이오테크 씨오., 엘티디. | Chimeric receptor polypeptides and uses thereof |
| CN113645953B (en) * | 2019-01-17 | 2025-03-25 | 英美偌科有限公司 | Formulations |
| GB201901306D0 (en) | 2019-01-30 | 2019-03-20 | Immunocore Ltd | Multi-domain binding molecules |
| GB201901305D0 (en) * | 2019-01-30 | 2019-03-20 | Immunocore Ltd | Specific binding molecules |
| WO2020163589A1 (en) | 2019-02-08 | 2020-08-13 | Genentech, Inc. | Diagnostic and therapeutic methods for cancer |
| GB201902277D0 (en) | 2019-02-19 | 2019-04-03 | King S College London | Therapeutic agents |
| EP3927728A2 (en) | 2019-02-21 | 2021-12-29 | Xencor, Inc. | Untargeted and targeted il-10 fc-fusion proteins |
| CA3134102A1 (en) | 2019-03-18 | 2020-09-24 | Ludwig Institute For Cancer Research Ltd | A2/ny-eso-1 specific t cell receptors and uses thereof |
| GB201904328D0 (en) | 2019-03-28 | 2019-05-15 | Immunocore Ltd | Specific binding molecules |
| KR20220005082A (en) | 2019-05-03 | 2022-01-12 | 바이오니즈, 엘엘씨 | Regulating the effect of gamma-C-cytokine signaling for the treatment of hair loss and hair loss-related problem symptoms |
| GB201915282D0 (en) | 2019-10-22 | 2019-12-04 | Immunocore Ltd | Specific binding molecules |
| GB202005779D0 (en) | 2020-04-21 | 2020-06-03 | Scancell Ltd | Anti-tumour immune responses |
| GB202006629D0 (en) | 2020-05-05 | 2020-06-17 | Immunocore Ltd | Specific binding molecules |
| GB202010329D0 (en) | 2020-07-06 | 2020-08-19 | Immunocore Ltd | Specific binding molecules |
| EP4196612A1 (en) | 2020-08-12 | 2023-06-21 | Genentech, Inc. | Diagnostic and therapeutic methods for cancer |
| CN112239495B (en) * | 2020-10-29 | 2022-04-12 | 上海药明生物技术有限公司 | Stable TCR structure and applications |
| WO2022184805A1 (en) | 2021-03-03 | 2022-09-09 | Immatics Biotechnologies Gmbh | Antigen binding proteins specifically binding sars-cov-2 antigenic peptides in complex with a major histocompatibility complex protein |
| KR20240004937A (en) | 2021-05-05 | 2024-01-11 | 이매틱스 바이오테크놀로지스 게엠베하 | BMA031 antigen-binding polypeptide |
| EP4113120A1 (en) | 2021-06-28 | 2023-01-04 | Immatics Biotechnologies GmbH | Method of characterizing the binding characteristics between a peptide of interest and mhc molecules |
| US20230024554A1 (en) | 2021-06-28 | 2023-01-26 | Immatics Biotechnologies Gmbh | Method of characterizing the binding characteristics between a peptide of interest and mhc molecules |
| EP4370540A2 (en) | 2021-07-12 | 2024-05-22 | Ludwig Institute for Cancer Research Ltd | T cell receptors specific for tumor-associated antigens and methods of use thereof |
| CN115724988B (en) * | 2021-08-26 | 2023-11-17 | 瑅安生物医药(杭州)有限公司 | A polypeptide fusion molecule close to natural molecules |
| EP4198052A1 (en) | 2021-12-15 | 2023-06-21 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Peptides and antigen binding proteins for use in immunotherapy against fibrolamellar hepatocellular carcinoma (fl-hcc) and other cancers |
| CA3250782A1 (en) | 2022-02-20 | 2023-08-24 | Immunocore Ltd | Hiv-specific binding molecules and tcr |
| JP2025526897A (en) | 2022-08-18 | 2025-08-15 | イムノコア リミテッド | Multidomain binding molecules |
| CN120076819A (en) | 2022-08-18 | 2025-05-30 | 英美偌科有限公司 | Multi-domain binding molecules |
| CN120077068A (en) | 2022-08-18 | 2025-05-30 | 英美偌科有限公司 | Multi-domain binding molecules |
| TW202417476A (en) | 2022-08-18 | 2024-05-01 | 英商英美偌科有限公司 | T cell receptors and fusion proteins thereof |
| WO2024067821A1 (en) * | 2022-09-30 | 2024-04-04 | 瑅安生物医药(杭州)有限公司 | Modified cell and use thereof |
| AU2023395989A1 (en) | 2022-12-16 | 2025-07-24 | Repertoire Immune Medicines, Inc. | T cell receptors binding hpv-16 epitopes |
| US12195534B2 (en) | 2023-01-06 | 2025-01-14 | Immunocore Limited | Binding molecules |
| WO2024146951A1 (en) | 2023-01-06 | 2024-07-11 | Immunocore Limited | Binding molecules against a prame peptide-hla complex |
| US12319747B2 (en) | 2023-07-03 | 2025-06-03 | Medicovestor, Inc. | Methods of using anti-SP17 immunotherapeutics |
| US12364777B2 (en) | 2023-10-20 | 2025-07-22 | Medicovestor, Inc. | Homodimeric antibodies for use in treating cancers and methods of use |
| TW202530269A (en) * | 2023-10-27 | 2025-08-01 | 大陸商北京可瑞生物科技有限公司 | T cell receptor-based multispecific polypeptide molecules and compostions and uses thereof |
| GB202320012D0 (en) | 2023-12-22 | 2024-02-07 | Immunocore Ltd | Bispecific molecules |
| US12116410B1 (en) | 2023-12-26 | 2024-10-15 | Medicovestor, Inc. | Methods of manufacturing dimeric antibodies |
| US12258396B1 (en) | 2024-02-02 | 2025-03-25 | Medicovestor, Inc. | Methods of using immunotherapeutics that bind folate receptor alpha |
| US12378314B1 (en) | 2024-02-02 | 2025-08-05 | Medicovestor, Inc. | Proteins that bind folate receptor alpha including fully-human antibodies |
| US12240900B1 (en) | 2024-02-02 | 2025-03-04 | Medicovestor, Inc. | Nucleic acids, vectors, and cells that encode antibodies and other proteins that bind folate receptor alpha |
| GB202406837D0 (en) | 2024-05-14 | 2024-06-26 | Immunocore Ltd | Screening methods |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2103059C (en) * | 1991-06-14 | 2005-03-22 | Paul J. Carter | Method for making humanized antibodies |
| WO1999060120A2 (en) * | 1998-05-19 | 1999-11-25 | Avidex Limited | Soluble t cell receptor |
| WO2000023087A1 (en) * | 1998-10-21 | 2000-04-27 | Sunol Molecular Corporation | Polyspecific binding molecules and uses thereof |
| AU2001261624A1 (en) * | 2000-05-25 | 2001-12-03 | Altor Bioscience Corporation | Modulation of t-cell receptor interactions |
| CN101712721A (en) * | 2000-06-05 | 2010-05-26 | 阿尔托生物科学有限公司 | T cell receptor fusions and conjugates and methods of use thereof |
| US20030017134A1 (en) * | 2001-06-19 | 2003-01-23 | Technion Research And Development Foundation Ltd. | Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer |
| PL208712B1 (en) * | 2001-08-31 | 2011-05-31 | Avidex Ltd | Soluble t cell receptor |
| EP1485075A4 (en) | 2002-02-20 | 2006-04-26 | Dyax Corp | Mhc-peptide complex binding ligands |
| NZ539225A (en) | 2002-10-09 | 2006-09-29 | Avidex Ltd | Single chain recombinant T cell receptors |
| GB0304068D0 (en) * | 2003-02-22 | 2003-03-26 | Avidex Ltd | Substances |
| DK1765860T3 (en) * | 2004-05-19 | 2009-03-09 | Immunocore Ltd | New-ESO-T. cell receptor with high affinity |
| US20090042285A1 (en) * | 2004-05-27 | 2009-02-12 | Weidanz Jon A | Antibodies at T cell receptor mimics, methods of production and uses thereof |
| AU2005247950B2 (en) * | 2004-05-27 | 2012-02-02 | Receptor Logic, Inc. | Antibodies as T cell receptor mimics, methods of production and uses thereof |
| US20100062001A1 (en) * | 2004-06-09 | 2010-03-11 | Technion Research & Development | Antibodies for selective apoptosis of cells |
| EP1809669A2 (en) | 2004-10-01 | 2007-07-25 | Avidex Ltd | T-cell receptors containing a non-native disulfide interchain bond linked to therapeutic agents |
| PT1976880T (en) * | 2005-12-21 | 2016-09-28 | Amgen Res Munich Gmbh | PHARMACEUTICAL COMPOSITIONS WITH SOLID ECA RESISTANCE |
| US20080044413A1 (en) * | 2005-12-21 | 2008-02-21 | Hammond Scott A | EphA2 BiTE molecules and uses thereof |
| GB0708585D0 (en) | 2007-05-03 | 2007-06-13 | Queen Mary & Westfield College | Novel antibody and use in diagnosis and therapy of arthropathies |
| GB0816096D0 (en) | 2008-09-04 | 2008-10-15 | Medigene Ltd | Diabetes t cell receptors |
| GB0908613D0 (en) | 2009-05-20 | 2009-06-24 | Immunocore Ltd | T Cell Reseptors |
| GB0911566D0 (en) * | 2009-07-03 | 2009-08-12 | Immunocore Ltd | T cell receptors |
-
2009
- 2009-05-20 GB GBGB0908613.3A patent/GB0908613D0/en not_active Ceased
-
2010
- 2010-05-19 JP JP2012511333A patent/JP5667171B2/en active Active
- 2010-05-19 ES ES16176249.7T patent/ES2672095T3/en active Active
- 2010-05-19 LT LTEP16176249.7T patent/LT3112377T/en unknown
- 2010-05-19 TR TR2019/05437T patent/TR201905437T4/en unknown
- 2010-05-19 EP EP16176246.3A patent/EP3112376B1/en not_active Revoked
- 2010-05-19 PT PT16176246T patent/PT3112376T/en unknown
- 2010-05-19 ES ES10720803.5T patent/ES2608653T3/en active Active
- 2010-05-19 LT LTEP16176246.3T patent/LT3112376T/en unknown
- 2010-05-19 US US13/319,597 patent/US10130721B2/en active Active
- 2010-05-19 SI SI201031358A patent/SI2432802T1/en unknown
- 2010-05-19 HU HUE16176246A patent/HUE043245T2/en unknown
- 2010-05-19 SI SI201031697T patent/SI3112377T1/en unknown
- 2010-05-19 HR HRP20170086TT patent/HRP20170086T1/en unknown
- 2010-05-19 SM SM20190232T patent/SMT201900232T1/en unknown
- 2010-05-19 DK DK16176249.7T patent/DK3112377T3/en active
- 2010-05-19 BR BRPI1013029A patent/BRPI1013029A2/en not_active Application Discontinuation
- 2010-05-19 EA EA201101660A patent/EA020841B1/en not_active IP Right Cessation
- 2010-05-19 EP EP16176249.7A patent/EP3112377B1/en not_active Revoked
- 2010-05-19 PT PT161762497T patent/PT3112377T/en unknown
- 2010-05-19 CN CN201080022523.6A patent/CN102439034B/en active Active
- 2010-05-19 SM SM20180364T patent/SMT201800364T1/en unknown
- 2010-05-19 AU AU2010250951A patent/AU2010250951B2/en active Active
- 2010-05-19 MX MX2011012184A patent/MX340168B/en active IP Right Grant
- 2010-05-19 SI SI201031883T patent/SI3112376T1/en unknown
- 2010-05-19 CA CA2968393A patent/CA2968393C/en active Active
- 2010-05-19 PL PL16176249T patent/PL3112377T3/en unknown
- 2010-05-19 TR TR2018/09945T patent/TR201809945T4/en unknown
- 2010-05-19 EP EP10720803.5A patent/EP2432802B1/en active Active
- 2010-05-19 CA CA2762604A patent/CA2762604C/en active Active
- 2010-05-19 LT LTEP10720803.5T patent/LT2432802T/en unknown
- 2010-05-19 PL PL10720803T patent/PL2432802T3/en unknown
- 2010-05-19 WO PCT/GB2010/000988 patent/WO2010133828A1/en not_active Ceased
- 2010-05-19 HU HUE10720803A patent/HUE032929T2/en unknown
- 2010-05-19 PT PT107208035T patent/PT2432802T/en unknown
- 2010-05-19 DK DK16176246.3T patent/DK3112376T3/en active
- 2010-05-19 HU HUE16176249A patent/HUE038342T2/en unknown
- 2010-05-19 SM SM20170067T patent/SMT201700067T1/en unknown
- 2010-05-19 ES ES16176246T patent/ES2721058T3/en active Active
- 2010-05-19 PL PL16176246T patent/PL3112376T3/en unknown
- 2010-05-19 DK DK10720803.5T patent/DK2432802T3/en active
-
2014
- 2014-12-11 JP JP2014250885A patent/JP2015096527A/en active Pending
-
2016
- 2016-12-30 CY CY20161101365T patent/CY1118405T1/en unknown
-
2017
- 2017-01-23 JP JP2017009529A patent/JP2017110019A/en active Pending
-
2018
- 2018-05-04 CY CY20181100507T patent/CY1120439T1/en unknown
- 2018-05-15 HR HRP20180757TT patent/HRP20180757T1/en unknown
- 2018-10-03 US US16/151,144 patent/US20190247512A1/en not_active Abandoned
-
2019
- 2019-04-08 US US16/378,505 patent/US10420846B2/en active Active
- 2019-04-08 US US16/378,481 patent/US10517960B2/en active Active
- 2019-04-08 US US16/378,501 patent/US10576162B2/en active Active
- 2019-04-09 HR HRP20190674TT patent/HRP20190674T1/en unknown
- 2019-04-12 CY CY20191100410T patent/CY1121558T1/en unknown
- 2019-05-08 JP JP2019088405A patent/JP2019172678A/en active Pending
-
2022
- 2022-09-02 US US17/929,682 patent/US20230241238A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB0908613D0 (en) | T Cell Reseptors | |
| IL216624A0 (en) | Fucosylation-deficient cells | |
| EP2475029A4 (en) | Battery | |
| GB0911566D0 (en) | T cell receptors | |
| EP2457078A4 (en) | Nanofluidic cell | |
| GB0908910D0 (en) | Fuel cell | |
| EP2478584A4 (en) | Battery cell | |
| EP2448051A4 (en) | Fuel cell | |
| GB201017421D0 (en) | Cell | |
| EP2413405A4 (en) | Fuel cell | |
| GB0913836D0 (en) | Fuel cell | |
| EP2441107A4 (en) | Thin battery | |
| GB0920775D0 (en) | Cells | |
| GB0913469D0 (en) | Cell support | |
| PL2405924T3 (en) | Plasma-adapted full electrolyte solution | |
| ZA201201864B (en) | Fuel cell | |
| GB0917143D0 (en) | Cell stack | |
| ZA201107671B (en) | Photovoltaic cell | |
| GB0920035D0 (en) | Cell | |
| GB0901675D0 (en) | Cells | |
| GB0908223D0 (en) | Cells | |
| HUE052153T2 (en) | Fucosylation-deficient cells | |
| GB0905615D0 (en) | Cell line | |
| TWI372482B (en) | Battery | |
| GB2471262B (en) | Photovoltaic cell |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |