JP2023536164A5 - - Google Patents

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Publication number
JP2023536164A5
JP2023536164A5 JP2023506326A JP2023506326A JP2023536164A5 JP 2023536164 A5 JP2023536164 A5 JP 2023536164A5 JP 2023506326 A JP2023506326 A JP 2023506326A JP 2023506326 A JP2023506326 A JP 2023506326A JP 2023536164 A5 JP2023536164 A5 JP 2023536164A5
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JP
Japan
Prior art keywords
dione
piperidine
oxoisoindorin
atoms
optionally substituted
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JP2023506326A
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English (en)
Japanese (ja)
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JP7819176B2 (ja
JP2023536164A (ja
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Priority claimed from PCT/IB2021/056924 external-priority patent/WO2022029573A1/en
Publication of JP2023536164A publication Critical patent/JP2023536164A/ja
Publication of JP2023536164A5 publication Critical patent/JP2023536164A5/ja
Application granted granted Critical
Publication of JP7819176B2 publication Critical patent/JP7819176B2/ja
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JP2023506326A 2020-08-03 2021-07-29 ヘテロアリール置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用 Active JP7819176B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063060349P 2020-08-03 2020-08-03
US63/060,349 2020-08-03
PCT/IB2021/056924 WO2022029573A1 (en) 2020-08-03 2021-07-29 Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof

Publications (3)

Publication Number Publication Date
JP2023536164A JP2023536164A (ja) 2023-08-23
JP2023536164A5 true JP2023536164A5 (enExample) 2024-08-02
JP7819176B2 JP7819176B2 (ja) 2026-02-24

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JP2023506326A Active JP7819176B2 (ja) 2020-08-03 2021-07-29 ヘテロアリール置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用

Country Status (5)

Country Link
US (1) US20230271940A1 (enExample)
EP (1) EP4188549A1 (enExample)
JP (1) JP7819176B2 (enExample)
CN (1) CN116134027B (enExample)
WO (1) WO2022029573A1 (enExample)

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JP2024515545A (ja) * 2021-04-05 2024-04-10 ブリストル-マイヤーズ スクイブ カンパニー がん治療のためのピリジニル置換オキソイソインドリン化合物
MX2024000313A (es) 2021-07-09 2024-03-06 Plexium Inc Compuestos de arilo y composiciones farmaceuticas que modulan la ikzf2.
CA3237577A1 (en) 2021-12-22 2023-06-29 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
CN116640122A (zh) * 2022-02-16 2023-08-25 苏州国匡医药科技有限公司 Ikzf2降解剂及包含其的药物组合物和用途
EP4493554A1 (en) 2022-03-17 2025-01-22 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
US20250215012A1 (en) * 2022-03-25 2025-07-03 Regents Of The University Of Michigan Ikzf2 degraders and uses thereof
WO2023201012A1 (en) * 2022-04-15 2023-10-19 Regents Of The University Of Michigan Ikzf2 degraders and uses thereof
JP2025531869A (ja) * 2022-09-09 2025-09-25 イノヴォ セラピューティクス、インコーポレイテッド CK1αおよびDUAL CK1α/GSPT1分解化合物
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