JP2022550919A5 - - Google Patents

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JP2022550919A5
JP2022550919A5 JP2022521584A JP2022521584A JP2022550919A5 JP 2022550919 A5 JP2022550919 A5 JP 2022550919A5 JP 2022521584 A JP2022521584 A JP 2022521584A JP 2022521584 A JP2022521584 A JP 2022521584A JP 2022550919 A5 JP2022550919 A5 JP 2022550919A5
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JP2022521584A
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JPWO2021076514A5 (https=
JP7795454B2 (ja
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JP2022521584A 2019-10-14 2020-10-13 (r)-2-[3-[4-アミノ-3-(2-フルオロ-4-フェノキシ-フェニル)ピラゾロ[3,4-d]ピリミジン-1-イル]ピペリジン-1-カルボニル]-4-メチル-4-[4-(オキセタン-3-イル)ピペラジン-1-イル]ペンタ-2-エンニトリルを投与することにより免疫性血小板減少症を治療する方法 Active JP7795454B2 (ja)

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JP2025129327A JP2025163155A (ja) 2019-10-14 2025-08-01 (r)-2-[3-[4-アミノ-3-(2-フルオロ-4-フェノキシ-フェニル)ピラゾロ[3,4-d]ピリミジン-1-イル]ピペリジン-1-カルボニル]-4-メチル-4-[4-(オキセタン-3-イル)ピペラジン-1-イル]ペンタ-2-エンニトリルを投与することにより免疫性血小板減少症を治療する方法

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US201962914688P 2019-10-14 2019-10-14
US62/914,688 2019-10-14
US201962951302P 2019-12-20 2019-12-20
US62/951,302 2019-12-20
PCT/US2020/055410 WO2021076514A1 (en) 2019-10-14 2020-10-13 Methods for treating immune thrombocytopenia by administering (r)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

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JP2025129327A Division JP2025163155A (ja) 2019-10-14 2025-08-01 (r)-2-[3-[4-アミノ-3-(2-フルオロ-4-フェノキシ-フェニル)ピラゾロ[3,4-d]ピリミジン-1-イル]ピペリジン-1-カルボニル]-4-メチル-4-[4-(オキセタン-3-イル)ピペラジン-1-イル]ペンタ-2-エンニトリルを投与することにより免疫性血小板減少症を治療する方法

Publications (4)

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JP2022550919A JP2022550919A (ja) 2022-12-05
JPWO2021076514A5 JPWO2021076514A5 (https=) 2023-10-20
JP2022550919A5 true JP2022550919A5 (https=) 2023-10-20
JP7795454B2 JP7795454B2 (ja) 2026-01-07

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JP2022521584A Active JP7795454B2 (ja) 2019-10-14 2020-10-13 (r)-2-[3-[4-アミノ-3-(2-フルオロ-4-フェノキシ-フェニル)ピラゾロ[3,4-d]ピリミジン-1-イル]ピペリジン-1-カルボニル]-4-メチル-4-[4-(オキセタン-3-イル)ピペラジン-1-イル]ペンタ-2-エンニトリルを投与することにより免疫性血小板減少症を治療する方法
JP2025129327A Pending JP2025163155A (ja) 2019-10-14 2025-08-01 (r)-2-[3-[4-アミノ-3-(2-フルオロ-4-フェノキシ-フェニル)ピラゾロ[3,4-d]ピリミジン-1-イル]ピペリジン-1-カルボニル]-4-メチル-4-[4-(オキセタン-3-イル)ピペラジン-1-イル]ペンタ-2-エンニトリルを投与することにより免疫性血小板減少症を治療する方法

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JP2025129327A Pending JP2025163155A (ja) 2019-10-14 2025-08-01 (r)-2-[3-[4-アミノ-3-(2-フルオロ-4-フェノキシ-フェニル)ピラゾロ[3,4-d]ピリミジン-1-イル]ピペリジン-1-カルボニル]-4-メチル-4-[4-(オキセタン-3-イル)ピペラジン-1-イル]ペンタ-2-エンニトリルを投与することにより免疫性血小板減少症を治療する方法

Country Status (12)

Country Link
US (3) US20210106584A1 (https=)
EP (1) EP4045051A1 (https=)
JP (2) JP7795454B2 (https=)
KR (1) KR20220080179A (https=)
CN (1) CN115209899A (https=)
AU (1) AU2020365951A1 (https=)
CA (1) CA3154257A1 (https=)
CO (1) CO2022006087A2 (https=)
IL (1) IL291994A (https=)
MX (1) MX2022004427A (https=)
TW (2) TWI877239B (https=)
WO (1) WO2021076514A1 (https=)

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MA45547A (fr) 2016-06-29 2019-05-08 Principia Biopharma Inc Formulations à libération modifiée à base de 2-[3-[4-amino-3-(2-fluoro-4-phénoxy-phényl)pyrazolo[3,4-d]pyrimidine-1-yl]pipéridine-1-carbonyl]-4-méthyl-4-[4-(oxétane-3-yl)pipérazine-1-yl]pent-2-ènenitrile
TWI877239B (zh) 2019-10-14 2025-03-21 美商普林斯匹亞生物製藥公司 藉由投予(R)-2-[3-[4-胺基-3-(2-氟-4-苯氧基-苯基)吡唑并[3,4-d]嘧啶-1-基]哌啶-1-羰基]-4-甲基-4-[4-(氧呾-3-基)哌-1-基]戊-2-烯腈來治療免疫血小板減少症之方法
JP2023511105A (ja) 2020-01-22 2023-03-16 プリンシピア バイオファーマ インコーポレイテッド 2-[3-[4-アミノ-3-(2-フルオロ-4-フェノキシ-フェニル)-1h-ピラゾロ[3,4-d]ピリミジン-1-イル]ピペリジン-1-カルボニル]-4-メチル-4-[4-(オキセタン-3-イル)ピペラジン-1-イル]ペンタ-2-エンニトリルの結晶形態
AU2022257016A1 (en) * 2021-04-16 2023-11-30 Principia Biopharma, Inc. Methods for treating drug and vaccine induced immune thrombocytopenia by administering specific compounds
TW202432135A (zh) * 2022-10-31 2024-08-16 美商普林斯匹亞生物製藥公司 藉由投予(r)-2-[3-[4-胺基-3-(2-氟-4-苯氧基-苯基)吡唑並[3,4-d]嘧啶-1-基]哌啶-1-羰基]-4-甲基-4-[4-氧雜環丁-3-基)哌𠯤-1-基]戊-2-烯腈治療免疫性血小板減少症的方法
AU2024306785A1 (en) * 2023-06-30 2026-02-19 Principia Biopharma Inc. Methods for treating persistent or chronic immune thrombocytopenia in children, adolescents and adults by administering (r)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy- phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4- methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

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