|
US5633234A
(en)
|
1993-01-22 |
1997-05-27 |
The Johns Hopkins University |
Lysosomal targeting of immunogens
|
|
US5773244A
(en)
|
1993-05-19 |
1998-06-30 |
Regents Of The University Of California |
Methods of making circular RNA
|
|
FR2709309B1
(fr)
|
1993-08-25 |
1995-11-10 |
Centre Nat Rech Scient |
Compositions cellulaires, préparation et utilisations thérapeutiques.
|
|
US5631236A
(en)
|
1993-08-26 |
1997-05-20 |
Baylor College Of Medicine |
Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk
|
|
US5641875A
(en)
|
1993-09-30 |
1997-06-24 |
University Of Pennsylvania |
DNA encoding chimeric IgG Fc receptor
|
|
US20030121063A1
(en)
*
|
1995-11-16 |
2003-06-26 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of use of mammalian retrotransposons
|
|
US6150160A
(en)
*
|
1995-11-16 |
2000-11-21 |
The John Hopkins University |
Compositions and methods of use of mammalian retrotransposons
|
|
US6576463B1
(en)
|
1999-01-15 |
2003-06-10 |
The Regents Of The University Of California |
Hybrid vectors for gene therapy
|
|
WO2001030965A2
(en)
|
1999-10-28 |
2001-05-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of in vivo gene transfer using a sleeping beauty transposon system
|
|
US7176243B2
(en)
|
2000-06-02 |
2007-02-13 |
The General Hospital Corporation |
CaR receptor as a mediator of migratory cell chemotaxis and/or chemokinesis
|
|
ATE338124T1
(de)
|
2000-11-07 |
2006-09-15 |
Hope City |
Cd19-spezifische umgezielte immunzellen
|
|
US8709412B2
(en)
|
2001-06-29 |
2014-04-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulation of TIM receptor activity in combination with cytoreductive therapy
|
|
US20060183226A1
(en)
*
|
2002-01-31 |
2006-08-17 |
Haruhiko Fujiwara |
Methods for retrotransposing long interspersed elements (lines)
|
|
AU2003219805B2
(en)
|
2002-02-15 |
2009-06-04 |
Eisai Inc. |
Electroporation methods for introducing bioactive agents into cells
|
|
US20080254027A1
(en)
|
2002-03-01 |
2008-10-16 |
Bernett Matthew J |
Optimized CD5 antibodies and methods of using the same
|
|
WO2003104470A2
(en)
|
2002-06-05 |
2003-12-18 |
Her Majesty In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada |
Retrons for gene targeting
|
|
SI1509244T1
(sl)
|
2002-06-06 |
2011-11-30 |
Immunicum An |
Nov postopek in spojina za izdelavo celične alogenične vakcine
|
|
EP1567014B1
(en)
|
2002-12-04 |
2011-09-28 |
Baylor Research Institute |
Rapid one-step method for generation of antigen loaded dendritic cell vaccine from precursors
|
|
WO2004072290A1
(en)
|
2003-02-07 |
2004-08-26 |
The Administrators Of The Tulane Educational Fund |
Mammalian retrotransposable elements
|
|
US8007805B2
(en)
|
2003-08-08 |
2011-08-30 |
Paladin Labs, Inc. |
Chimeric antigens for breaking host tolerance to foreign antigens
|
|
WO2005019429A2
(en)
|
2003-08-22 |
2005-03-03 |
Potentia Pharmaceuticals, Inc. |
Compositions and methods for enhancing phagocytosis or phagocyte activity
|
|
ZA200704252B
(en)
|
2004-10-25 |
2009-09-30 |
Cellerant Therapeutics Inc |
Methods of expanding myeloid cell populations and uses thereof
|
|
GB2421948A
(en)
|
2004-12-30 |
2006-07-12 |
Ist Superiore Sanita |
Retrotransposon inhibition to treat cancer
|
|
US20060188891A1
(en)
|
2005-02-23 |
2006-08-24 |
Bickmore William D Jr |
Methods and apparatus for controlling DNA amplification
|
|
US20060257359A1
(en)
|
2005-02-28 |
2006-11-16 |
Cedric Francois |
Modifying macrophage phenotype for treatment of disease
|
|
US20090191202A1
(en)
|
2005-09-29 |
2009-07-30 |
Jamieson Catriona Helen M |
Methods for manipulating phagocytosis mediated by CD47
|
|
AU2007232356A1
(en)
|
2006-04-03 |
2007-10-11 |
Keele University |
Targeted therapy
|
|
US20110171729A1
(en)
*
|
2006-05-04 |
2011-07-14 |
Ab Maxis Inc. |
Method for Producing Stable Mammalian Cell Lines Producing High Levels of Recombinant Proteins
|
|
EP2046347A2
(en)
|
2006-07-20 |
2009-04-15 |
Gourmetceuticals, LLC |
Phosphorylated glucomannan polysaccharide for receptor mediated activation and maturation of monocyte-derived dendritic cells
|
|
US7833789B2
(en)
|
2006-08-01 |
2010-11-16 |
Fondazione Centro San Raffaele Del Monte Tabor |
Monocyte cell
|
|
CN1951499A
(zh)
|
2006-10-09 |
2007-04-25 |
中国农业大学 |
一种细胞免疫疫苗及其制备方法
|
|
EP2160461B1
(en)
|
2007-07-04 |
2012-08-08 |
Max-Delbrück-Centrum für Molekulare Medizin (MDC) |
Hyperactive variants of the transposase protein of the transposon system sleeping beauty
|
|
EP2055784A1
(en)
*
|
2007-10-31 |
2009-05-06 |
Bundesrepublik Deutschland, letztvertreten durch den Präsidenten des Paul-Ehrlich-Instituts Prof. Dr. Johannes Löwer |
Controlled activation of non-LTR retrotransposons in mammals
|
|
ES2582340T3
(es)
|
2008-01-15 |
2016-09-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Métodos para manipular fagocitosis mediada por CD47
|
|
WO2010010119A1
(en)
|
2008-07-22 |
2010-01-28 |
Ablynx Nv |
Amino acid sequences directed against multitarget scavenger receptors and polypeptides
|
|
RU2011111640A
(ru)
|
2008-08-29 |
2012-10-10 |
Симфоген А/С (Dk) |
Антитела против cd5
|
|
US9080211B2
(en)
|
2008-10-24 |
2015-07-14 |
Epicentre Technologies Corporation |
Transposon end compositions and methods for modifying nucleic acids
|
|
EP2248903A1
(en)
*
|
2009-04-29 |
2010-11-10 |
Universitat Autònoma De Barcelona |
Methods and reagents for efficient and targeted gene transfer to monocytes and macrophages
|
|
US20110287038A1
(en)
|
2010-04-16 |
2011-11-24 |
Kevin Slawin |
Method for treating solid tumors
|
|
WO2012005763A1
(en)
|
2010-07-06 |
2012-01-12 |
The Scripps Research Institute |
Use of myeloid-like progenitor cell populations to treat tumors
|
|
JP5861191B2
(ja)
|
2010-09-30 |
2016-02-16 |
国立大学法人 熊本大学 |
ミエロイド系血液細胞の製造方法
|
|
US9206479B2
(en)
|
2011-02-09 |
2015-12-08 |
University Of Rochester |
Methods and compositions related to Staufen 1 binding sites formed by duplexing Alu elements
|
|
WO2012133947A1
(en)
|
2011-03-30 |
2012-10-04 |
Riken |
Functional nucleic acid molecule and use thereof
|
|
WO2013036201A1
(en)
|
2011-09-06 |
2013-03-14 |
Agency For Science, Technology And Research |
Polypeptide vaccine
|
|
WO2013051718A1
(ja)
|
2011-10-07 |
2013-04-11 |
国立大学法人三重大学 |
キメラ抗原受容体
|
|
US9149519B2
(en)
|
2012-01-17 |
2015-10-06 |
New York University |
Chimeric human immunodeficiency virus type 1 (HIV-1) with enhanced dendritic cell and macrophage tropism comprising the simian immunodeficiency virus (SIV) minimal Vpx packaging domain
|
|
KR102100388B1
(ko)
|
2012-02-06 |
2020-04-13 |
인히브릭스, 인크. |
Cd47 항체 및 그 사용 방법
|
|
US20140140989A1
(en)
|
2012-02-06 |
2014-05-22 |
Inhibrx Llc |
Non-Platelet Depleting and Non-Red Blood Cell Depleting CD47 Antibodies and Methods of Use Thereof
|
|
CA2861491C
(en)
|
2012-02-13 |
2020-08-25 |
Seattle Children's Hospital D/B/A Seattle Children's Research Institute |
Bispecific chimeric antigen receptors and therapeutic uses thereof
|
|
WO2013123088A1
(en)
|
2012-02-14 |
2013-08-22 |
Loma Linda University |
Agents and method for treating inflammation-related conditions and diseases
|
|
EP2639313A1
(en)
|
2012-03-14 |
2013-09-18 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
High-resolution transcriptome of human macrophages
|
|
WO2013151665A2
(en)
*
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins associated with human disease
|
|
BR112014029417B1
(pt)
|
2012-05-25 |
2023-03-07 |
Cellectis |
Método ex vivo para a preparação de células t para imunoterapia
|
|
PT2692865E
(pt)
|
2012-07-30 |
2015-02-06 |
Nbe Therapeutics Llc |
Identificação mediada por transposição de proteínas funcionais ou de ligação específicas
|
|
US20140037606A1
(en)
|
2012-08-06 |
2014-02-06 |
Eyal Amiel |
Cell-based, anti-cancer vaccines
|
|
BR112015013431A2
(pt)
|
2012-12-12 |
2017-11-14 |
Vasculox Inc |
anticorpos monoclonais ou respectivos fragmentos ligantes de antígenos, composição farmacêutica, e usos de anticorpo monoclonal ou respectivo fragmento ligante de antígenos
|
|
US9221908B2
(en)
|
2012-12-12 |
2015-12-29 |
Vasculox, Inc. |
Therapeutic CD47 antibodies
|
|
WO2014121840A1
(en)
|
2013-02-07 |
2014-08-14 |
Medizinische Hochschule Hannover |
Induced dendritic cells and uses thereof
|
|
SE537429C2
(sv)
|
2013-02-14 |
2015-04-28 |
Scania Cv Ab |
Samtidig skattning av åtminstone massa och rullmotstånd förett fordon
|
|
WO2014134412A1
(en)
|
2013-03-01 |
2014-09-04 |
Regents Of The University Of Minnesota |
Talen-based gene correction
|
|
EP2970985A1
(en)
|
2013-03-14 |
2016-01-20 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to modify cells for therapeutic objectives
|
|
WO2014145252A2
(en)
|
2013-03-15 |
2014-09-18 |
Milone Michael C |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
CN105873952A
(zh)
|
2013-10-31 |
2016-08-17 |
弗莱德哈钦森癌症研究中心 |
经修饰的造血干细胞/祖细胞和非t效应细胞及其用途
|
|
KR102375998B1
(ko)
|
2014-02-14 |
2022-03-21 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
키메라 항원 수용체 및 제조방법
|
|
CN106456749B
(zh)
|
2014-03-11 |
2021-03-30 |
小利兰·斯坦福大学托管委员会 |
抗SIRPα抗体和双特异性巨噬细胞增强型抗体
|
|
US20170233452A1
(en)
|
2014-04-23 |
2017-08-17 |
Immusoft Corporation |
Chimeric antigen receptors specific to avb6 integrin and methods of use thereof to treat cancer
|
|
CN104004095B
(zh)
|
2014-06-04 |
2016-11-23 |
博生吉医药科技(苏州)有限公司 |
一种cd7纳米抗体、其编码序列及应用
|
|
BR112017001183A2
(pt)
|
2014-07-21 |
2017-11-28 |
Novartis Ag |
tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado
|
|
US10544201B2
(en)
|
2014-07-31 |
2020-01-28 |
Cellectis |
ROR1 specific multi-chain chimeric antigen receptor
|
|
DK4074735T3
(da)
|
2014-08-28 |
2025-07-14 |
Bioatla Inc |
Betinget aktive kimæriske antigenreceptorer til modificerede t-celler
|
|
WO2016030501A1
(en)
*
|
2014-08-28 |
2016-03-03 |
Centre National De La Recherche Scientifique - Cnrs - |
Synthetic alu-retrotransposon vectors for gene therapy
|
|
CA2972714A1
(en)
|
2014-09-09 |
2016-03-17 |
Unum Therapeutics |
Chimeric receptors and uses thereof in immune therapy
|
|
ES2946697T3
(es)
|
2014-09-10 |
2023-07-24 |
Miltenyi Biotec Bv & Co Kg |
Una población celular para su uso en el tratamiento de cáncer
|
|
CA2961950A1
(en)
|
2014-09-28 |
2016-03-31 |
The Regents Of The University Of California |
Modulation of stimulatory and non-stimulatory myeloid cells
|
|
BR112017007003A2
(pt)
|
2014-10-07 |
2017-12-19 |
Cellectis |
método para modulação de atividade de células imunes induzidas por car
|
|
MA41538A
(fr)
|
2014-10-17 |
2017-12-26 |
Baylor College Medicine |
Cellules immunitaires bipartites et tripartites de signalisation
|
|
KR20170074235A
(ko)
|
2014-10-31 |
2017-06-29 |
메사추세츠 인스티튜트 오브 테크놀로지 |
면역 세포로의 생체분자의 전달
|
|
EP3221358B1
(en)
|
2014-11-18 |
2021-07-21 |
Janssen Pharmaceutica, N.V. |
Cd47 antibodies, methods, and uses
|
|
US11041158B2
(en)
|
2014-12-22 |
2021-06-22 |
AgBiome, Inc. |
Optimization methods for making a synthetic gene
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
KR102763121B1
(ko)
|
2015-02-06 |
2025-02-04 |
내셔널 유니버시티 오브 싱가포르 |
치료적 면역 세포의 효능의 향상 방법
|
|
US20170151281A1
(en)
|
2015-02-19 |
2017-06-01 |
Batu Biologics, Inc. |
Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
|
|
KR102624023B1
(ko)
|
2015-02-24 |
2024-01-11 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
결합-촉발된 전사 스위치 및 이들의 이용 방법
|
|
JP7237449B2
(ja)
|
2015-02-27 |
2023-03-13 |
アイセル・ジーン・セラピューティクス・エルエルシー |
血液系腫瘍を標的としたキメラ抗体受容体（ＣＡＲｓ）の構成およびその使用方法
|
|
US9777064B2
(en)
|
2015-03-17 |
2017-10-03 |
Chimera Bioengineering, Inc. |
Smart CAR devices, DE CAR polypeptides, side CARs and uses thereof
|
|
US10214591B1
(en)
*
|
2015-04-03 |
2019-02-26 |
Alienor Farma |
Monoclonal antibody to human line-1 ORF2 protein and method for early detection of transforming cells in pre-neoplastic tissues of a human subject
|
|
US10786549B2
(en)
|
2015-04-23 |
2020-09-29 |
Baylor College Of Medicine |
CD5 chimeric antigen receptor for adoptive T cell therapy
|
|
CN114425077A
(zh)
|
2015-05-18 |
2022-05-03 |
起源生物医药公司 |
Sirp多肽组合物和使用方法
|
|
US10434153B1
(en)
|
2015-05-20 |
2019-10-08 |
Kim Leslie O'Neill |
Use of car and bite technology coupled with an scFv from an antibody against human thymidine kinase 1 to specifically target tumors
|
|
GB201509413D0
(en)
|
2015-06-01 |
2015-07-15 |
Ucl Business Plc |
Fusion protein
|
|
EP3302558A4
(en)
|
2015-06-01 |
2019-01-16 |
The Rockefeller University |
ANTI-TUMOR MEDIUM AND METHOD OF USE
|
|
WO2016205749A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Novel crispr enzymes and systems
|
|
IL315940A
(en)
|
2015-07-28 |
2024-11-01 |
Univ Pennsylvania |
Altered monocytes/macrophages expressing chimeric antigen receptors and their uses
|
|
CA2993429A1
(en)
|
2015-07-31 |
2017-02-09 |
Tarveda Therapeutics, Inc. |
Compositions and methods for immuno-oncology therapies
|
|
GB2592821B
(en)
|
2015-07-31 |
2022-01-12 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
AU2016304794B2
(en)
|
2015-08-07 |
2021-07-15 |
ALX Oncology Inc. |
Constructs having a SIRP-alpha domain or variant thereof
|
|
US11352439B2
(en)
|
2015-08-13 |
2022-06-07 |
Kim Leslie O'Neill |
Macrophage CAR (MOTO-CAR) in immunotherapy
|
|
WO2017025944A2
(en)
|
2015-08-13 |
2017-02-16 |
Brigham Young University |
Macrophage car (moto-car) in imunotherapy
|
|
EP3347026A4
(en)
|
2015-09-09 |
2019-05-08 |
Seattle Children's Hospital (DBA Seattle Children's Research Institute) |
GENEMANIPULATION OF MACROPHAGES FOR IMMUNOTHERAPY
|
|
WO2017046259A1
(en)
|
2015-09-16 |
2017-03-23 |
Ethris Gmbh |
Improved transposon system for gene delivery
|
|
ES3063691T3
(en)
|
2015-09-22 |
2026-04-20 |
Univ Wuerzburg J Maximilians |
A method for high level and stable gene transfer in lymphocytes
|
|
CN105154473B
(zh)
|
2015-09-30 |
2019-03-01 |
上海细胞治疗研究院 |
一种高效安全的转座子整合系统及其用途
|
|
CN108472317A
(zh)
|
2015-11-09 |
2018-08-31 |
爱普瑞希斯有限公司 |
修饰免疫细胞及其用途
|
|
US10946042B2
(en)
|
2015-12-01 |
2021-03-16 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for selective phagocytosis of human cancer cells
|
|
EP3202783A1
(en)
|
2016-02-02 |
2017-08-09 |
Ecole Polytechnique Fédérale de Lausanne (EPFL) |
Engineered antigen presenting cells and uses thereof
|
|
US12220451B2
(en)
|
2016-02-04 |
2025-02-11 |
Duke University |
Cell-based vaccine compositions and methods of use
|
|
WO2017133175A1
(en)
|
2016-02-04 |
2017-08-10 |
Nanjing Legend Biotech Co., Ltd. |
Engineered mammalian cells for cancer therapy
|
|
GB201602473D0
(en)
|
2016-02-11 |
2016-03-30 |
Horizon Discovery Ltd |
Replicative transposon system
|
|
US20170275665A1
(en)
|
2016-02-24 |
2017-09-28 |
Board Of Regents, The University Of Texas System |
Direct crispr spacer acquisition from rna by a reverse-transcriptase-cas1 fusion protein
|
|
US10617749B1
(en)
|
2016-02-24 |
2020-04-14 |
Duke University |
Composition of matter and methods for alteration of dendritic cell metabolism to augment cancer vaccine efficacy
|
|
US20200063157A9
(en)
|
2016-02-26 |
2020-02-27 |
Poseida Therapeutics, Inc. |
Transposon system and methods of use
|
|
EP3219803A1
(en)
|
2016-03-15 |
2017-09-20 |
Max-Delbrück-Centrum für Molekulare Medizin |
Enhanced sleeping beauty transposons, kits and methods of transposition
|
|
US20180186855A1
(en)
|
2016-03-23 |
2018-07-05 |
Alector Llc |
Chimeric receptors and methods of use thereof
|
|
KR20230148844A
(ko)
|
2016-03-29 |
2023-10-25 |
유니버시티 오브 써던 캘리포니아 |
암을 표적하는 키메라 항원 수용체
|
|
WO2017184553A1
(en)
|
2016-04-18 |
2017-10-26 |
Baylor College Of Medicine |
Cancer gene therapy targeting cd47
|
|
US10875919B2
(en)
|
2016-04-26 |
2020-12-29 |
Alector Llc |
Chimeric receptors and methods of use thereof
|
|
WO2017213979A1
(en)
|
2016-06-06 |
2017-12-14 |
St. Jude Children's Research Hospital |
Anti-cd7 chimeric antigen receptor and method of use thereof
|
|
WO2017214553A1
(en)
|
2016-06-09 |
2017-12-14 |
The General Hospital Corporation |
Modulating the cellular stress response
|
|
CN109642231A
(zh)
|
2016-06-17 |
2019-04-16 |
博德研究所 |
Vi型crispr直向同源物和系统
|
|
CN107523545A
(zh)
|
2016-06-20 |
2017-12-29 |
上海细胞治疗研究院 |
一种高效稳定表达抗体的杀伤性细胞及其用途
|
|
WO2018038684A1
(en)
|
2016-08-26 |
2018-03-01 |
Agency For Science, Technology And Research |
Macrophage stimulating protein receptor (or ron - recepteur d' origine nantais) antibodies and uses thereof
|
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
|
AU2017335634A1
(en)
|
2016-09-27 |
2019-03-14 |
Cero Therapeutics, Inc. |
Chimeric engulfment receptor molecules
|
|
US20190263928A1
(en)
|
2016-09-30 |
2019-08-29 |
Baylor College Of Medicine |
Adaptive chimeric antigen receptor t-cell design
|
|
US11376332B2
(en)
|
2016-10-15 |
2022-07-05 |
Baylor College Of Medicine |
Platform for enhanced targeted delivery
|
|
WO2018073394A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Cell death inducing chimeric antigen receptors
|
|
EP3529276A4
(en)
|
2016-10-21 |
2020-06-17 |
Arch Oncology, Inc. |
CD47 THERAPEUTIC ANTIBODIES
|
|
US20190276549A1
(en)
|
2016-11-01 |
2019-09-12 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
|
EP4545649A3
(en)
|
2016-11-11 |
2025-06-04 |
Bio-Rad Laboratories, Inc. |
Methods for processing nucleic acid samples
|
|
CN110506128A
(zh)
|
2016-12-09 |
2019-11-26 |
博德研究所 |
基于crispr效应系统的诊断
|
|
AU2017371070B2
(en)
|
2016-12-09 |
2025-01-02 |
Alector Llc |
Anti-SIRP-alpha antibodies and methods of use thereof
|
|
US20190336615A1
(en)
|
2017-01-27 |
2019-11-07 |
Silverback Therapeutics, Inc. |
Tumor targeting conjugates and methods of use thereof
|
|
CN117959418A
(zh)
|
2017-03-13 |
2024-05-03 |
波赛达治疗公司 |
用于选择性消除和替换造血干细胞的组合物和方法
|
|
KR20190140918A
(ko)
|
2017-03-15 |
2019-12-20 |
더 브로드 인스티튜트, 인코퍼레이티드 |
바이러스 검출을 위한 crispr 이펙터 시스템 기반 진단
|
|
WO2018191490A1
(en)
|
2017-04-13 |
2018-10-18 |
The Trustees Of The University Of Pennsylvania |
Use of gene editing to generate universal tcr re-directed t cells for adoptive immunotherapy
|
|
US10415017B2
(en)
|
2017-05-17 |
2019-09-17 |
Thunder Biotech, Inc. |
Transgenic macrophages, chimeric antigen receptors, and associated methods
|
|
CN110944652A
(zh)
|
2017-06-12 |
2020-03-31 |
爱莫里大学 |
T细胞抗原靶向的嵌合抗原受体(car)以及在细胞疗法中的用途
|
|
TWI828625B
(zh)
|
2017-06-25 |
2024-01-11 |
美商西雅圖免疫公司 |
引導及導航控制蛋白質以及彼之製造及使用方法
|
|
WO2019010551A1
(pt)
|
2017-07-10 |
2019-01-17 |
Instituto De Biologia Molecular Do Paraná - Ibmp |
Plataforma genética para superexpressão heteróloga associada à seleção de células altamente produtoras de proteínas
|
|
US20210087548A1
(en)
|
2017-07-24 |
2021-03-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compositions and Methods for Inducing Protein Function
|
|
BR112020001653A2
(pt)
|
2017-07-26 |
2020-07-21 |
Forty Seven, Inc. |
anticorpos anti-sirp-alfa e métodos relacionados
|
|
CN109306340B
(zh)
|
2017-07-27 |
2023-06-06 |
上海细胞治疗研究院 |
一种高效扩增全t细胞的人工抗原递呈细胞及其用途
|
|
CN109337872B
(zh)
|
2017-07-27 |
2023-06-23 |
上海细胞治疗研究院 |
高效扩增car-t细胞的人工抗原递呈细胞及其用途
|
|
WO2019032624A1
(en)
|
2017-08-08 |
2019-02-14 |
Pionyr Immunotherapeutics, Inc. |
COMPOSITIONS AND METHODS FOR DEACTIVATING TREM1-EXPRESSING MESHLOID CELLS
|
|
EP3678680A4
(en)
|
2017-09-05 |
2021-12-01 |
Regeneron Pharmaceuticals, Inc. |
ADMINISTRATION OF A GENE EDITING SYSTEM CONTAINING A SINGLE RETROVIRAL PARTICLE AND METHODS OF GENERATION AND USE
|
|
AU2018329741B2
(en)
|
2017-09-08 |
2025-02-20 |
Poseida Therapeutics, Inc. |
Compositions and methods for chimeric ligand receptor (CLR)-mediated conditional gene expression
|
|
EP3735460A4
(en)
|
2017-09-18 |
2021-08-11 |
Exuma Biotech Corp. |
METHODS AND COMPOSITIONS FOR THE GENETIC MODIFICATION AND EXPANSION OF LYMPHOCYTES AND THE REGULATION OF THE ACTIVITY OF THE LATTER
|
|
EP4714966A2
(en)
|
2017-09-26 |
2026-03-25 |
Cero Therapeutics Holdings, Inc. |
Chimeric engulfment receptor molecules and methods of use
|
|
WO2019070704A1
(en)
|
2017-10-02 |
2019-04-11 |
Georgia Tech Research Corporation |
METHODS AND COMPOSITIONS FOR ENGINEERING SYNTHESIS BIOLOGICAL SWITCHES FOR REMOTE CONTROL OF BIOLOGICAL ACTIVITY
|
|
WO2019070843A1
(en)
|
2017-10-03 |
2019-04-11 |
Board Of Regents, The University Of Texas System |
INVERSE TRANSCRIPTASE WITH LTR-FREE BACKLIGHTS AND USES THEREOF
|
|
AU2018352221B2
(en)
*
|
2017-10-16 |
2024-04-18 |
Aadigen, Llc |
Peptides and nanoparticles for intracellular delivery of mRNA
|
|
GB201717974D0
(en)
|
2017-10-31 |
2017-12-13 |
Univ Court Of The Univ Of Aberdeen |
Modified receptors
|
|
WO2019090175A1
(en)
|
2017-11-02 |
2019-05-09 |
Arbor Biotechnologies, Inc. |
Novel crispr-associated transposon systems and components
|
|
CN109971716B
(zh)
|
2017-12-28 |
2023-08-01 |
上海细胞治疗研究院 |
自分泌cd47抗体的egfr特异性car-t细胞及其用途
|
|
EP3759226A4
(en)
*
|
2018-03-02 |
2022-06-15 |
Generation Bio Co. |
IDENTIFICATION AND CHARACTERIZATION OF GENOMIC SAFE HARBOR (GSH) IN HUMAN AND MURINE GENOMES AND VIRAL AND NON-VIRAL VECTOR COMPOSITIONS FOR TARGETED INTEGRATION AT IDENTIFIED GSH LOCI
|
|
GB2572005A
(en)
|
2018-03-16 |
2019-09-18 |
Univ Court Univ Of Edinburgh |
Macrophage-based therapy
|
|
EP3774906A1
(en)
|
2018-03-28 |
2021-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
|
WO2019191332A1
(en)
|
2018-03-28 |
2019-10-03 |
Cero Therapeutics, Inc. |
Chimeric engulfment receptors and uses thereof for neurodegenerative diseases
|
|
MX2020010241A
(es)
|
2018-03-28 |
2020-10-16 |
Cero Therapeutics Inc |
Composiciones de inmunoterapia celular y usos de las mismas.
|
|
EP3814519A1
(en)
|
2018-06-26 |
2021-05-05 |
The Broad Institute, Inc. |
Crispr/cas and transposase based amplification compositions, systems and methods
|
|
CN112689673A
(zh)
|
2018-07-11 |
2021-04-20 |
埃克斯基因美国公司 |
转座体使能的dna/rna测序（ted rna-seq）
|
|
JP2021530212A
(ja)
|
2018-07-13 |
2021-11-11 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California |
レトロトランスポゾンベースの送達媒体及びその使用方法
|
|
EP3844272A1
(en)
|
2018-08-28 |
2021-07-07 |
Flagship Pioneering Innovations VI, LLC |
Methods and compositions for modulating a genome
|
|
EP3628309A1
(en)
|
2018-09-28 |
2020-04-01 |
Universität Heidelberg |
Method of making oral dosage forms
|
|
GB201818110D0
(en)
|
2018-11-06 |
2018-12-19 |
Macrophox Ltd |
Monocytes for cancer targeting
|
|
WO2020097193A1
(en)
|
2018-11-06 |
2020-05-14 |
The Regents Of The University Of California |
Chimeric antigen receptors for phagocytosis
|
|
CN113544266A
(zh)
|
2018-12-17 |
2021-10-22 |
博德研究所 |
Crispr相关转座酶系统和其使用方法
|
|
CA3117950A1
(en)
|
2018-12-19 |
2020-06-25 |
Amgen Inc. |
Apparatus for resolving imaging problems caused by the meniscus
|
|
EP3911735A4
(en)
*
|
2019-01-16 |
2023-07-12 |
Beam Therapeutics, Inc. |
MODIFIED IMMUNE CELLS WITH INCREASED ANTINEOPLASTIC ACTIVITY AND RESISTANCE TO IMMUNOSUPPRESSION
|
|
WO2020191233A1
(en)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
EP3962497A4
(en)
|
2019-04-30 |
2023-01-18 |
Myeloid Therapeutics, Inc. |
GENETICALLY ENGINEERED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
|
|
US20220001031A1
(en)
|
2019-04-30 |
2022-01-06 |
Myeloid Therapeutics, Inc. |
Engineered chimeric fusion protein compositions and methods of use thereof
|
|
US20220378824A1
(en)
|
2019-04-30 |
2022-12-01 |
Myeloid Therapeutics, Inc. |
Engineered chimeric fusion protein compositions and methods of use thereof
|
|
US11026973B2
(en)
|
2019-04-30 |
2021-06-08 |
Myeloid Therapeutics, Inc. |
Engineered phagocytic receptor compositions and methods of use thereof
|
|
JP2022536684A
(ja)
|
2019-06-11 |
2022-08-18 |
マイエロイド・セラピューティクス，インコーポレーテッド |
マクロファージ特異的エンゲージャー組成物およびその使用方法
|
|
KR20220024647A
(ko)
|
2019-06-19 |
2022-03-03 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
원형 폴리리보뉴클레오티드의 투여 방법
|
|
JP7759311B2
(ja)
|
2019-07-19 |
2025-10-23 |
フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー |
リコンビナーゼ組成物及び使用方法
|
|
CN114981409A
(zh)
|
2019-09-03 |
2022-08-30 |
美洛德生物医药公司 |
用于基因组整合的方法和组合物
|
|
WO2021102042A1
(en)
|
2019-11-19 |
2021-05-27 |
The Broad Institute, Inc. |
Retrotransposons and use thereof
|
|
WO2021119538A1
(en)
|
2019-12-11 |
2021-06-17 |
Myeloid Therapeutics, Inc. |
Therapeutic cell compositions and methods for manufacture and uses thereof
|
|
KR20230053735A
(ko)
|
2020-03-04 |
2023-04-21 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
게놈의 조정을 위한 개선된 방법 및 조성물
|
|
BR112022017713A2
(pt)
|
2020-03-04 |
2022-11-16 |
Flagship Pioneering Innovations Vi Llc |
Métodos e composições para modular um genoma
|
|
CN116209756A
(zh)
|
2020-03-04 |
2023-06-02 |
旗舰先锋创新Vi有限责任公司 |
调控基因组的方法和组合物
|
|
CA3174553A1
(en)
|
2020-03-05 |
2021-09-10 |
Flagship Pioneering Innovations Vi, Llc |
Host defense suppressing methods and compositions for modulating a genome
|
|
EP4232583A1
(en)
|
2020-10-21 |
2023-08-30 |
Massachusetts Institute of Technology |
Systems, methods, and compositions for site-specific genetic engineering using programmable addition via site-specific targeting elements (paste)
|
|
EP4240367A4
(en)
|
2020-11-04 |
2024-10-16 |
Myeloid Therapeutics, Inc. |
MODIFIED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
|
|
BR112023023642A2
(pt)
|
2021-05-11 |
2024-01-30 |
Myeloid Therapeutics Inc |
Métodos e composições para integração genômica
|
|
EP4399315A2
(en)
|
2021-09-10 |
2024-07-17 |
Myeloid Therapeutics, Inc. |
Macrophage specific engager compositions and methods of use thereof
|
|
WO2025128722A2
(en)
|
2023-12-11 |
2025-06-19 |
Myeloid Therapeutics, Inc. |
Methods and compositions for genomic integration
|