|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4470461A
(en)
|
1982-09-30 |
1984-09-11 |
Phillips Petroleum Company |
Organic nitro compounds as cosurfactants in enhanced oil recovery processes
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
GB8809129D0
(en)
|
1988-04-18 |
1988-05-18 |
Celltech Ltd |
Recombinant dna methods vectors and host cells
|
|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
AU649066B2
(en)
|
1990-07-25 |
1994-05-12 |
Syngene, Inc. |
Circular extension for generating multiple nucleic acid complements
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
|
FI941572L
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
|
|
US5858784A
(en)
|
1991-12-17 |
1999-01-12 |
The Regents Of The University Of California |
Expression of cloned genes in the lung by aerosol- and liposome-based delivery
|
|
US5633234A
(en)
|
1993-01-22 |
1997-05-27 |
The Johns Hopkins University |
Lysosomal targeting of immunogens
|
|
WO1994025591A1
(en)
|
1993-04-29 |
1994-11-10 |
Unilever N.V. |
PRODUCTION OF ANTIBODIES OR (FUNCTIONALIZED) FRAGMENTS THEREOF DERIVED FROM HEAVY CHAIN IMMUNOGLOBULINS OF $i(CAMELIDAE)
|
|
US5773244A
(en)
|
1993-05-19 |
1998-06-30 |
Regents Of The University Of California |
Methods of making circular RNA
|
|
FR2709309B1
(fr)
|
1993-08-25 |
1995-11-10 |
Centre Nat Rech Scient |
Compositions cellulaires, préparation et utilisations thérapeutiques.
|
|
US5631236A
(en)
|
1993-08-26 |
1997-05-20 |
Baylor College Of Medicine |
Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk
|
|
US5641875A
(en)
|
1993-09-30 |
1997-06-24 |
University Of Pennsylvania |
DNA encoding chimeric IgG Fc receptor
|
|
US5639642A
(en)
|
1994-06-16 |
1997-06-17 |
Novo Nordisk A/S |
Synthetic leader peptide sequences
|
|
US6300090B1
(en)
|
1994-07-29 |
2001-10-09 |
The Rockefeller University |
Methods of use of viral vectors to deliver antigen to dendritic cells
|
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5766903A
(en)
|
1995-08-23 |
1998-06-16 |
University Technology Corporation |
Circular RNA and uses thereof
|
|
US20030121063A1
(en)
|
1995-11-16 |
2003-06-26 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of use of mammalian retrotransposons
|
|
US6150160A
(en)
|
1995-11-16 |
2000-11-21 |
The John Hopkins University |
Compositions and methods of use of mammalian retrotransposons
|
|
US6734014B1
(en)
|
1996-02-08 |
2004-05-11 |
The United States Of America As Represented By The Department Of Health And Human Services |
Methods and compositions for transforming dendritic cells and activating T cells
|
|
EP1056834A2
(en)
|
1998-02-20 |
2000-12-06 |
The Rockefeller University |
Apoptotic cell-mediated antigen presentation to dendritic cells
|
|
US6210931B1
(en)
|
1998-11-30 |
2001-04-03 |
The United States Of America As Represented By The Secretary Of Agriculture |
Ribozyme-mediated synthesis of circular RNA
|
|
US6576463B1
(en)
|
1999-01-15 |
2003-06-10 |
The Regents Of The University Of California |
Hybrid vectors for gene therapy
|
|
AU1100201A
(en)
|
1999-10-28 |
2001-05-08 |
Board Of Trustees Of The Leland Stanford Junior University |
Methods of in vivo gene transfer using a sleeping beauty transposon system
|
|
AU2001257362A1
(en)
|
2000-04-28 |
2001-11-12 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
The use of tolerogenic dendritic cells for enhancing tolerogenicity in a host and methods for making the same
|
|
US7176243B2
(en)
|
2000-06-02 |
2007-02-13 |
The General Hospital Corporation |
CaR receptor as a mediator of migratory cell chemotaxis and/or chemokinesis
|
|
AU2001297703B2
(en)
|
2000-11-07 |
2006-10-19 |
City Of Hope |
CD19-specific redirected immune cells
|
|
US8709412B2
(en)
|
2001-06-29 |
2014-04-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulation of TIM receptor activity in combination with cytoreductive therapy
|
|
US20060183226A1
(en)
|
2002-01-31 |
2006-08-17 |
Haruhiko Fujiwara |
Methods for retrotransposing long interspersed elements (lines)
|
|
CA2476452A1
(en)
|
2002-02-15 |
2003-08-28 |
Zycos Inc. |
Electroporation methods for introducing bioactive agents into cells
|
|
US20080254027A1
(en)
|
2002-03-01 |
2008-10-16 |
Bernett Matthew J |
Optimized CD5 antibodies and methods of using the same
|
|
AU2003233734C1
(en)
|
2002-06-05 |
2011-01-20 |
Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food |
Retrons for gene targeting
|
|
EP1509244B1
(en)
|
2002-06-06 |
2011-07-27 |
Immunicum AB |
New method and composition for producing a cellular allogeneic vaccine
|
|
US20060239962A1
(en)
|
2002-12-04 |
2006-10-26 |
Banchereau Jacques F |
Rapid one-step generation of antigen loaded dendritic cell vaccine from precursors
|
|
US20070037759A1
(en)
|
2003-02-07 |
2007-02-15 |
Administrators Of The Tulane Educational Fund, The |
Mammalian retrotransposable elements
|
|
US8007805B2
(en)
|
2003-08-08 |
2011-08-30 |
Paladin Labs, Inc. |
Chimeric antigens for breaking host tolerance to foreign antigens
|
|
US8198020B2
(en)
|
2003-08-22 |
2012-06-12 |
Potentia Pharmaceuticals, Inc. |
Compositions and methods for enhancing phagocytosis or phagocyte activity
|
|
US7709625B2
(en)
|
2004-06-10 |
2010-05-04 |
The Board Of Regents Of The University Of Texas |
Methods and compositions for bone marrow stem cell-derived macrophage delivery of genes for gene therapy
|
|
CN105168250B
(zh)
|
2004-10-25 |
2019-02-05 |
塞勒兰特治疗公司 |
增殖骨髓细胞群体的方法及其应用
|
|
GB2421948A
(en)
*
|
2004-12-30 |
2006-07-12 |
Ist Superiore Sanita |
Retrotransposon inhibition to treat cancer
|
|
US20060188891A1
(en)
|
2005-02-23 |
2006-08-24 |
Bickmore William D Jr |
Methods and apparatus for controlling DNA amplification
|
|
US20060257359A1
(en)
|
2005-02-28 |
2006-11-16 |
Cedric Francois |
Modifying macrophage phenotype for treatment of disease
|
|
US20090191202A1
(en)
|
2005-09-29 |
2009-07-30 |
Jamieson Catriona Helen M |
Methods for manipulating phagocytosis mediated by CD47
|
|
US7926300B2
(en)
|
2005-11-18 |
2011-04-19 |
Cree, Inc. |
Adaptive adjustment of light output of solid state lighting panels
|
|
EP2004237A1
(en)
|
2006-04-03 |
2008-12-24 |
Keele University |
Targeted therapy
|
|
JP2009535065A
(ja)
|
2006-05-04 |
2009-10-01 |
アブマクシス・インコーポレイテツド |
組換えタンパク質の高レベルを産生する安定した哺乳動物細胞系を作製するための方法
|
|
EP2046347A2
(en)
|
2006-07-20 |
2009-04-15 |
Gourmetceuticals, LLC |
Phosphorylated glucomannan polysaccharide for receptor mediated activation and maturation of monocyte-derived dendritic cells
|
|
US7833789B2
(en)
|
2006-08-01 |
2010-11-16 |
Fondazione Centro San Raffaele Del Monte Tabor |
Monocyte cell
|
|
CN1951499A
(zh)
|
2006-10-09 |
2007-04-25 |
中国农业大学 |
一种细胞免疫疫苗及其制备方法
|
|
US10155038B2
(en)
|
2007-02-02 |
2018-12-18 |
Yale University |
Cells prepared by transient transfection and methods of use thereof
|
|
EP2160461B1
(en)
|
2007-07-04 |
2012-08-08 |
Max-Delbrück-Centrum für Molekulare Medizin (MDC) |
Hyperactive variants of the transposase protein of the transposon system sleeping beauty
|
|
EP2055784A1
(en)
|
2007-10-31 |
2009-05-06 |
Bundesrepublik Deutschland, letztvertreten durch den Präsidenten des Paul-Ehrlich-Instituts Prof. Dr. Johannes Löwer |
Controlled activation of non-LTR retrotransposons in mammals
|
|
AU2009205665B2
(en)
|
2008-01-15 |
2013-12-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for manipulating phagocytosis mediated by CD47
|
|
WO2010010119A1
(en)
|
2008-07-22 |
2010-01-28 |
Ablynx Nv |
Amino acid sequences directed against multitarget scavenger receptors and polypeptides
|
|
MX2011000970A
(es)
|
2008-08-29 |
2011-03-15 |
Symphogen As |
Anticuerpos anti-cd5.
|
|
EP2331680B1
(en)
|
2008-09-22 |
2017-05-03 |
Baylor College Of Medicine |
Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters
|
|
US9080211B2
(en)
|
2008-10-24 |
2015-07-14 |
Epicentre Technologies Corporation |
Transposon end compositions and methods for modifying nucleic acids
|
|
EP2248903A1
(en)
*
|
2009-04-29 |
2010-11-10 |
Universitat Autònoma De Barcelona |
Methods and reagents for efficient and targeted gene transfer to monocytes and macrophages
|
|
US9101674B2
(en)
|
2010-03-29 |
2015-08-11 |
Vib Vzw |
Targeting and in vivo imaging of tumor-associated macrophages
|
|
AU2011239569B2
(en)
|
2010-04-16 |
2014-07-24 |
Baylor College Of Medicine |
Method for treating solid tumors
|
|
WO2012005763A1
(en)
|
2010-07-06 |
2012-01-12 |
The Scripps Research Institute |
Use of myeloid-like progenitor cell populations to treat tumors
|
|
ES2754394T3
(es)
|
2010-09-08 |
2020-04-17 |
Chemotherapeutisches Forschungsinstitut Georg Speyer Haus |
Receptores de antígenos quiméricos con una región bisagra optimizada
|
|
WO2012043651A1
(ja)
|
2010-09-30 |
2012-04-05 |
国立大学法人 熊本大学 |
ミエロイド系血液細胞の製造方法
|
|
US9206479B2
(en)
|
2011-02-09 |
2015-12-08 |
University Of Rochester |
Methods and compositions related to Staufen 1 binding sites formed by duplexing Alu elements
|
|
EP3792359A1
(en)
|
2011-03-30 |
2021-03-17 |
Transine Therapeutics Limited |
Functional nucleic acid molecule and use thereof
|
|
PL3586861T3
(pl)
|
2011-06-08 |
2022-05-23 |
Translate Bio, Inc. |
Kompozycje nanocząstek lipidowych i sposoby dostarczania mrna
|
|
JP6153526B2
(ja)
|
2011-09-06 |
2017-06-28 |
エージェンシー フォー サイエンス，テクノロジー アンド リサーチ |
ポリペプチドワクチン
|
|
WO2013051718A1
(ja)
|
2011-10-07 |
2013-04-11 |
国立大学法人三重大学 |
キメラ抗原受容体
|
|
US9149519B2
(en)
|
2012-01-17 |
2015-10-06 |
New York University |
Chimeric human immunodeficiency virus type 1 (HIV-1) with enhanced dendritic cell and macrophage tropism comprising the simian immunodeficiency virus (SIV) minimal Vpx packaging domain
|
|
KR102338833B1
(ko)
|
2012-02-06 |
2021-12-13 |
인히브릭스, 인크. |
Cd47 항체 및 그 사용 방법
|
|
US20140140989A1
(en)
|
2012-02-06 |
2014-05-22 |
Inhibrx Llc |
Non-Platelet Depleting and Non-Red Blood Cell Depleting CD47 Antibodies and Methods of Use Thereof
|
|
JP6850528B2
(ja)
|
2012-02-13 |
2021-03-31 |
シアトル チルドレンズ ホスピタル ドゥーイング ビジネス アズ シアトル チルドレンズ リサーチ インスティテュート |
二重特異性キメラ抗原受容体およびその治療的使用
|
|
WO2013123088A1
(en)
|
2012-02-14 |
2013-08-22 |
Loma Linda University |
Agents and method for treating inflammation-related conditions and diseases
|
|
EP2639313A1
(en)
|
2012-03-14 |
2013-09-18 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
High-resolution transcriptome of human macrophages
|
|
KR102437522B1
(ko)
|
2012-05-25 |
2022-08-26 |
셀렉티스 |
면역요법을 위한 동종이형 및 면역억제제 저항성인 ｔ 세포의 조작 방법
|
|
CN103483452B
(zh)
|
2012-06-12 |
2021-08-13 |
上海细胞治疗集团有限公司 |
双信号独立的嵌合抗原受体及其用途
|
|
ES2528892T3
(es)
|
2012-07-30 |
2015-02-13 |
Nbe-Therapeutics Llc |
Identificación mediada por trasposición de proteínas de unión o funcionales específicas
|
|
US20140037606A1
(en)
|
2012-08-06 |
2014-02-06 |
Eyal Amiel |
Cell-based, anti-cancer vaccines
|
|
AU2013327136A1
(en)
|
2012-10-02 |
2015-04-16 |
Memorial Sloan-Kettering Cancer Center |
Compositions and methods for immunotherapy
|
|
MX2015007446A
(es)
|
2012-12-12 |
2015-12-07 |
Vasculox Inc |
Anticuerpos terapeuticos para cd47.
|
|
US9221908B2
(en)
|
2012-12-12 |
2015-12-29 |
Vasculox, Inc. |
Therapeutic CD47 antibodies
|
|
CN105101997B
(zh)
|
2013-02-06 |
2018-11-09 |
印希彼有限合伙公司 |
不减少血小板和不减少血红细胞的cd47抗体及其使用方法
|
|
WO2014121840A1
(en)
|
2013-02-07 |
2014-08-14 |
Medizinische Hochschule Hannover |
Induced dendritic cells and uses thereof
|
|
PT2961831T
(pt)
|
2013-02-26 |
2020-10-12 |
Memorial Sloan Kettering Cancer Center |
Composições e métodos para imunoterapêutica
|
|
WO2014134412A1
(en)
|
2013-03-01 |
2014-09-04 |
Regents Of The University Of Minnesota |
Talen-based gene correction
|
|
WO2014153114A1
(en)
|
2013-03-14 |
2014-09-25 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to modify cells for therapeutic objectives
|
|
EP2970426B1
(en)
|
2013-03-15 |
2019-08-28 |
Michael C. Milone |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
MX389160B
(es)
|
2013-10-31 |
2025-03-20 |
Hutchinson Fred Cancer Res |
Células no t efectoras y madre/progenitoras hematopoyéticas modificadas y usos de estas.
|
|
LT3424955T
(lt)
|
2013-12-25 |
2025-06-25 |
Daiichi Sankyo Company, Limited |
Anti-trop2 antikūno ir vaisto konjugato gamybos būdas
|
|
EP3656864A1
(en)
|
2014-02-14 |
2020-05-27 |
Board of Regents, The University of Texas System |
Chimeric antigen receptors and methods of making
|
|
AU2015229448B2
(en)
|
2014-03-11 |
2020-09-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Anti SIRP-alpha antibodies and Bi-specific Macrophage Enhancing antibodies
|
|
WO2015164627A1
(en)
|
2014-04-23 |
2015-10-29 |
Discovery Genomics, Inc. |
Chimeric antigen receptors specific to avb6 integrin and methods of use thereof to treat cancer
|
|
CN104004095B
(zh)
|
2014-06-04 |
2016-11-23 |
博生吉医药科技(苏州)有限公司 |
一种cd7纳米抗体、其编码序列及应用
|
|
US10407683B2
(en)
|
2014-07-16 |
2019-09-10 |
Modernatx, Inc. |
Circular polynucleotides
|
|
TWI750110B
(zh)
|
2014-07-21 |
2021-12-21 |
瑞士商諾華公司 |
使用人類化抗-ｂｃｍａ嵌合抗原受體治療癌症
|
|
JP2017522893A
(ja)
|
2014-07-31 |
2017-08-17 |
セレクティスＣｅｌｌｅｃｔｉｓ |
Ｒｏｒ１特異的多重鎖キメラ抗原受容体
|
|
ES2791248T3
(es)
|
2014-08-19 |
2020-11-03 |
Novartis Ag |
Receptor antigénico quimérico (CAR) anti-CD123 para su uso en el tratamiento del cáncer
|
|
WO2016033331A1
(en)
|
2014-08-28 |
2016-03-03 |
Bioatla, Llc |
Conditionally active chimeric antigen receptors for modified t-cells
|
|
WO2016030501A1
(en)
*
|
2014-08-28 |
2016-03-03 |
Centre National De La Recherche Scientifique - Cnrs - |
Synthetic alu-retrotransposon vectors for gene therapy
|
|
US20180133252A9
(en)
|
2014-09-09 |
2018-05-17 |
Unum Therapeutics Inc. |
Chimeric receptors and uses thereof in immune therapy
|
|
ES2946697T3
(es)
|
2014-09-10 |
2023-07-24 |
Miltenyi Biotec Bv & Co Kg |
Una población celular para su uso en el tratamiento de cáncer
|
|
CA2961950A1
(en)
|
2014-09-28 |
2016-03-31 |
The Regents Of The University Of California |
Modulation of stimulatory and non-stimulatory myeloid cells
|
|
JP2017531430A
(ja)
|
2014-10-07 |
2017-10-26 |
セレクティスＣｅｌｌｅｃｔｉｓ |
Ｃａｒによって誘導される免疫細胞の活性を調節するための方法
|
|
MA41538A
(fr)
|
2014-10-17 |
2017-12-26 |
Baylor College Medicine |
Cellules immunitaires bipartites et tripartites de signalisation
|
|
JP7523203B2
(ja)
|
2014-10-31 |
2024-07-26 |
マサチューセッツ インスティテュート オブ テクノロジー |
生体分子の免疫細胞への送達
|
|
CA2967379A1
(en)
|
2014-11-18 |
2016-05-26 |
Janssen Pharmaceutica Nv |
Cd47 antibodies, methods, and uses
|
|
WO2016106184A1
(en)
|
2014-12-22 |
2016-06-30 |
AgBiome, Inc. |
Methods for making a synthetic gene
|
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
CN113713091A
(zh)
|
2015-02-06 |
2021-11-30 |
新加坡国立大学 |
工程免疫细胞及其用途和生产方法
|
|
WO2016130845A1
(en)
|
2015-02-11 |
2016-08-18 |
Loma Linda University |
A method for utilizing engineered dendritic cells to induce gut-homing regulatory t cells and treat gut inflammation
|
|
US20170151281A1
(en)
|
2015-02-19 |
2017-06-01 |
Batu Biologics, Inc. |
Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
|
|
WO2016138034A1
(en)
|
2015-02-24 |
2016-09-01 |
The Regents Of The University Of California |
Binding-triggered transcriptional switches and methods of use thereof
|
|
JP7237449B2
(ja)
|
2015-02-27 |
2023-03-13 |
アイセル・ジーン・セラピューティクス・エルエルシー |
血液系腫瘍を標的としたキメラ抗体受容体（ＣＡＲｓ）の構成およびその使用方法
|
|
WO2016149254A1
(en)
|
2015-03-17 |
2016-09-22 |
Chimera Bioengineering, Inc. |
Smart car devices, de car polypeptides, side cars and uses thereof
|
|
US10214591B1
(en)
*
|
2015-04-03 |
2019-02-26 |
Alienor Farma |
Monoclonal antibody to human line-1 ORF2 protein and method for early detection of transforming cells in pre-neoplastic tissues of a human subject
|
|
EP3286225B1
(en)
|
2015-04-23 |
2020-07-01 |
Baylor College of Medicine |
Cd5 chimeric antigen receptor for adoptive t cell therapy
|
|
CA2994935A1
(en)
|
2015-05-18 |
2016-11-24 |
Ab Initio Biotherapeutics, Inc. |
Sirp polypeptide compositions and methods of use
|
|
US10434153B1
(en)
|
2015-05-20 |
2019-10-08 |
Kim Leslie O'Neill |
Use of car and bite technology coupled with an scFv from an antibody against human thymidine kinase 1 to specifically target tumors
|
|
EP3302558A4
(en)
|
2015-06-01 |
2019-01-16 |
The Rockefeller University |
ANTI-TUMOR MEDIUM AND METHOD OF USE
|
|
GB201509413D0
(en)
|
2015-06-01 |
2015-07-15 |
Ucl Business Plc |
Fusion protein
|
|
CA3012607A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Crispr enzymes and systems
|
|
US20190008897A1
(en)
|
2015-07-22 |
2019-01-10 |
University Of Washington |
Compositions and methods for producing pro-inflammatory macrophages
|
|
RU2766690C2
(ru)
|
2015-07-28 |
2022-03-15 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Модифицированные моноциты/макрофаги, экспрессирующие химерные антигенные рецепторы, и их применения
|
|
GB2592821B
(en)
|
2015-07-31 |
2022-01-12 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
EP3328377A4
(en)
|
2015-07-31 |
2019-03-13 |
Tarveda Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR IMMUNE ONCOLOGY THERAPIES
|
|
WO2017027422A1
(en)
|
2015-08-07 |
2017-02-16 |
Alexo Therapeutics Inc. |
Constructs having a sirp-alpha domain or variant thereof
|
|
US11352439B2
(en)
|
2015-08-13 |
2022-06-07 |
Kim Leslie O'Neill |
Macrophage CAR (MOTO-CAR) in immunotherapy
|
|
CN108243607A
(zh)
|
2015-09-09 |
2018-07-03 |
西雅图儿童医院（Dba西雅图儿童研究所） |
用于免疫疗法的巨噬细胞的遗传工程
|
|
EP3350335B1
(en)
|
2015-09-16 |
2019-11-27 |
T-CURX GmbH |
Improved transposon system for gene delivery
|
|
EP4706680A3
(en)
|
2015-09-22 |
2026-03-25 |
Julius-Maximilians-Universität Würzburg |
A method for high level and stable gene transfer in lymphocytes
|
|
CN105154473B
(zh)
|
2015-09-30 |
2019-03-01 |
上海细胞治疗研究院 |
一种高效安全的转座子整合系统及其用途
|
|
KR20180054600A
(ko)
|
2015-10-13 |
2018-05-24 |
브라이엄 영 유니버시티 |
면역치료에서의 대식세포 키메라 항원 수용체(moto-car)
|
|
CA3004738A1
(en)
|
2015-11-09 |
2017-05-18 |
Aperisys, Inc. |
Modified immune cells and uses thereof
|
|
US10946042B2
(en)
|
2015-12-01 |
2021-03-16 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for selective phagocytosis of human cancer cells
|
|
EP3202783A1
(en)
|
2016-02-02 |
2017-08-09 |
Ecole Polytechnique Fédérale de Lausanne (EPFL) |
Engineered antigen presenting cells and uses thereof
|
|
WO2017133175A1
(en)
|
2016-02-04 |
2017-08-10 |
Nanjing Legend Biotech Co., Ltd. |
Engineered mammalian cells for cancer therapy
|
|
US12220451B2
(en)
|
2016-02-04 |
2025-02-11 |
Duke University |
Cell-based vaccine compositions and methods of use
|
|
GB201602473D0
(en)
|
2016-02-11 |
2016-03-30 |
Horizon Discovery Ltd |
Replicative transposon system
|
|
US9820350B2
(en)
|
2016-02-19 |
2017-11-14 |
Cooper Technologies Company |
Configurable lighting system
|
|
US10617749B1
(en)
|
2016-02-24 |
2020-04-14 |
Duke University |
Composition of matter and methods for alteration of dendritic cell metabolism to augment cancer vaccine efficacy
|
|
US20170275665A1
(en)
|
2016-02-24 |
2017-09-28 |
Board Of Regents, The University Of Texas System |
Direct crispr spacer acquisition from rna by a reverse-transcriptase-cas1 fusion protein
|
|
US20200063157A9
(en)
|
2016-02-26 |
2020-02-27 |
Poseida Therapeutics, Inc. |
Transposon system and methods of use
|
|
EP3219803A1
(en)
|
2016-03-15 |
2017-09-20 |
Max-Delbrück-Centrum für Molekulare Medizin |
Enhanced sleeping beauty transposons, kits and methods of transposition
|
|
US20180186855A1
(en)
|
2016-03-23 |
2018-07-05 |
Alector Llc |
Chimeric receptors and methods of use thereof
|
|
WO2017172981A2
(en)
|
2016-03-29 |
2017-10-05 |
University Of Southern California |
Chimeric antigen receptors targeting cancer
|
|
US11649284B2
(en)
|
2016-04-18 |
2023-05-16 |
Baylor College Of Medicine |
Cancer gene therapy targeting CD47
|
|
US10875919B2
(en)
|
2016-04-26 |
2020-12-29 |
Alector Llc |
Chimeric receptors and methods of use thereof
|
|
US11390658B2
(en)
|
2016-06-06 |
2022-07-19 |
St. Jude Children's Research Hospital |
Anti-CD7 chimeric antigen receptor and method of use thereof
|
|
WO2017214553A1
(en)
|
2016-06-09 |
2017-12-14 |
The General Hospital Corporation |
Modulating the cellular stress response
|
|
CA3028158A1
(en)
|
2016-06-17 |
2017-12-21 |
The Broad Institute, Inc. |
Type vi crispr orthologs and systems
|
|
CN107523545A
(zh)
|
2016-06-20 |
2017-12-29 |
上海细胞治疗研究院 |
一种高效稳定表达抗体的杀伤性细胞及其用途
|
|
EP3504244A4
(en)
|
2016-08-26 |
2020-08-19 |
Agency for Science, Technology and Research |
MACROPHAGE-STIMULATING PROTEIN RECEPTOR ANTIBODIES (OR OF NANTAIS ORIGINAL RON-RECEPTOR) AND THEIR USES
|
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
|
EP4089116A1
(en)
|
2016-09-27 |
2022-11-16 |
Cero Therapeutics, Inc. |
Chimeric engulfment receptor molecules
|
|
WO2018064626A1
(en)
|
2016-09-30 |
2018-04-05 |
Baylor College Of Medicine |
Adaptive chimeric antigen receptor t-cell design
|
|
WO2018071058A1
(en)
|
2016-10-15 |
2018-04-19 |
Baylor College Of Medicine |
Platform for enhanced targeted cell delivery
|
|
WO2018073394A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Cell death inducing chimeric antigen receptors
|
|
EP3529276A4
(en)
|
2016-10-21 |
2020-06-17 |
Arch Oncology, Inc. |
CD47 THERAPEUTIC ANTIBODIES
|
|
SG11201903693QA
(en)
|
2016-11-01 |
2019-05-30 |
Genmab Bv |
Polypeptide variants and uses thereof
|
|
KR102709829B1
(ko)
|
2016-11-11 |
2024-09-24 |
바이오 래드 래버러토리스 인코오포레이티드 |
핵산 샘플을 프로세싱하는 방법
|
|
CA3049961A1
(en)
|
2016-12-09 |
2018-06-14 |
The Broad Institute, Inc. |
Crispr effector system based diagnostics
|
|
CN118027200A
(zh)
|
2016-12-09 |
2024-05-14 |
艾利妥 |
抗SIRPα抗体及其使用方法
|
|
WO2018140831A2
(en)
|
2017-01-27 |
2018-08-02 |
Silverback Therapeutics, Inc. |
Tumor targeting conjugates and methods of use thereof
|
|
AU2018235756B2
(en)
|
2017-03-13 |
2024-08-08 |
Poseida Therapeutics, Inc. |
Compositions and methods for selective elimination and replacement of hematopoietic stem cells
|
|
CN111108220B
(zh)
|
2017-03-15 |
2024-11-19 |
博德研究所 |
用于病毒检测的基于crispr效应系统的诊断
|
|
WO2018191490A1
(en)
|
2017-04-13 |
2018-10-18 |
The Trustees Of The University Of Pennsylvania |
Use of gene editing to generate universal tcr re-directed t cells for adoptive immunotherapy
|
|
US10415017B2
(en)
|
2017-05-17 |
2019-09-17 |
Thunder Biotech, Inc. |
Transgenic macrophages, chimeric antigen receptors, and associated methods
|
|
JP2020525537A
(ja)
|
2017-06-12 |
2020-08-27 |
エモリー ユニバーシティー |
Ｔ細胞抗原標的キメラ抗原受容体（ｃａｒ）、及び細胞療法での使用
|
|
TWI828625B
(zh)
|
2017-06-25 |
2024-01-11 |
美商西雅圖免疫公司 |
引導及導航控制蛋白質以及彼之製造及使用方法
|
|
WO2019010551A1
(pt)
|
2017-07-10 |
2019-01-17 |
Instituto De Biologia Molecular Do Paraná - Ibmp |
Plataforma genética para superexpressão heteróloga associada à seleção de células altamente produtoras de proteínas
|
|
WO2019023347A1
(en)
|
2017-07-26 |
2019-01-31 |
Forty Seven, Inc. |
ANTI-SIRP-ALPHA ANTIBODIES AND ASSOCIATED METHODS
|
|
CN109306340B
(zh)
|
2017-07-27 |
2023-06-06 |
上海细胞治疗研究院 |
一种高效扩增全t细胞的人工抗原递呈细胞及其用途
|
|
CN109337872B
(zh)
|
2017-07-27 |
2023-06-23 |
上海细胞治疗研究院 |
高效扩增car-t细胞的人工抗原递呈细胞及其用途
|
|
WO2019032624A1
(en)
|
2017-08-08 |
2019-02-14 |
Pionyr Immunotherapeutics, Inc. |
COMPOSITIONS AND METHODS FOR DEACTIVATING TREM1-EXPRESSING MESHLOID CELLS
|
|
WO2019050948A1
(en)
|
2017-09-05 |
2019-03-14 |
Regeneron Pharmaceuticals, Inc. |
ADMINISTRATION OF A GENE EDITION SYSTEM HAVING ONLY ONE RETROVIRAL PARTICLE AND METHODS OF GENERATING AND USING
|
|
AU2018329741B2
(en)
|
2017-09-08 |
2025-02-20 |
Poseida Therapeutics, Inc. |
Compositions and methods for chimeric ligand receptor (CLR)-mediated conditional gene expression
|
|
CN111479921B
(zh)
|
2017-09-18 |
2024-08-02 |
埃克苏马生物技术公司 |
用于以基因方式修饰且扩增淋巴细胞以及调节其活性的方法及组合物
|
|
EP3688032B1
(en)
|
2017-09-26 |
2025-11-05 |
Cero Therapeutics Holdings, Inc. |
Chimeric engulfment receptor molecules and methods of use
|
|
US12467050B2
(en)
|
2017-10-02 |
2025-11-11 |
Georgia Tech Research Corporation |
Methods and compositions for engineering synthetic bioswitches for remote control of biological activity
|
|
US11352611B2
(en)
|
2017-10-03 |
2022-06-07 |
Board Of Regents, The University Of Texas System |
Non-LTR-retroelement reverse transcriptase and uses thereof
|
|
GB201717974D0
(en)
|
2017-10-31 |
2017-12-13 |
Univ Court Of The Univ Of Aberdeen |
Modified receptors
|
|
WO2019090175A1
(en)
|
2017-11-02 |
2019-05-09 |
Arbor Biotechnologies, Inc. |
Novel crispr-associated transposon systems and components
|
|
CN109971716B
(zh)
|
2017-12-28 |
2023-08-01 |
上海细胞治疗研究院 |
自分泌cd47抗体的egfr特异性car-t细胞及其用途
|
|
US11572557B2
(en)
|
2018-01-29 |
2023-02-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Photoreversible acylation reagents
|
|
KR20200120917A
(ko)
|
2018-02-02 |
2020-10-22 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
키메라 항원 수용체를 발현하는 변형된 단핵구/대식세포/수지상 세포 및 단백질 응집체와 연관이 있는 질환 및 장애에서의 용도
|
|
AU2019226526B2
(en)
|
2018-03-02 |
2025-12-04 |
Generation Bio Co. |
Identifying and characterizing genomic safe harbors (GSH) in humans and murine genomes, and viral and non-viral vector compositions for targeted integration at an identified GSH loci
|
|
GB2572005A
(en)
|
2018-03-16 |
2019-09-18 |
Univ Court Univ Of Edinburgh |
Macrophage-based therapy
|
|
US20210015865A1
(en)
|
2018-03-28 |
2021-01-21 |
Cero Therapeutics, Inc. |
Chimeric engulfment receptors and uses thereof for neurodegenerative diseases
|
|
JP7444781B2
(ja)
|
2018-03-28 |
2024-03-06 |
セロ・セラピューティクス・インコーポレイテッド |
細胞免疫療法組成物およびその使用
|
|
WO2019191334A1
(en)
|
2018-03-28 |
2019-10-03 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
|
SG11202009626QA
(en)
|
2018-04-20 |
2020-10-29 |
Medizinische Hochschule Hannover |
Chimeric antigen receptor and car-t cells that bind a herpes virus antigen
|
|
CA3098865A1
(en)
|
2018-05-02 |
2019-11-07 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of phospholipase a2 receptor chimeric autoantibody receptor t cells
|
|
SG11202011240YA
(en)
|
2018-06-26 |
2020-12-30 |
Broad Inst Inc |
Crispr/cas and transposase based amplification compositions, systems and methods
|
|
US20210222163A1
(en)
|
2018-07-11 |
2021-07-22 |
X Gen Us Co. |
Transposome enabled dna/rna-sequencing (ted rna-seq)
|
|
JP2021530212A
(ja)
|
2018-07-13 |
2021-11-11 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California |
レトロトランスポゾンベースの送達媒体及びその使用方法
|
|
CN113286880A
(zh)
*
|
2018-08-28 |
2021-08-20 |
旗舰先锋创新Vi有限责任公司 |
调控基因组的方法和组合物
|
|
EP3628309A1
(en)
|
2018-09-28 |
2020-04-01 |
Universität Heidelberg |
Method of making oral dosage forms
|
|
EP3876977A1
(en)
|
2018-11-06 |
2021-09-15 |
The Regents Of The University Of California |
Chimeric antigen receptors for phagocytosis
|
|
GB201818110D0
(en)
|
2018-11-06 |
2018-12-19 |
Macrophox Ltd |
Monocytes for cancer targeting
|
|
CA3124110A1
(en)
*
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Crispr-associated transposase systems and methods of use thereof
|
|
WO2020132327A1
(en)
|
2018-12-19 |
2020-06-25 |
The Trustees Of The University Of Pennsylvania |
Use of cd2/5/7 knock-out anti-cd2/5/7 chimeric antigen receptor t cells against t cell lymphomas and leukemias
|
|
CA3117950A1
(en)
|
2018-12-19 |
2020-06-25 |
Amgen Inc. |
Apparatus for resolving imaging problems caused by the meniscus
|
|
US20220133790A1
(en)
*
|
2019-01-16 |
2022-05-05 |
Beam Therapeutics Inc. |
Modified immune cells having enhanced anti-neoplasia activity and immunosuppression resistance
|
|
CA3135531A1
(en)
|
2019-04-30 |
2020-11-05 |
Daniel Getts |
Engineered chimeric fusion protein compositions and methods of use thereof
|
|
US20220001031A1
(en)
|
2019-04-30 |
2022-01-06 |
Myeloid Therapeutics, Inc. |
Engineered chimeric fusion protein compositions and methods of use thereof
|
|
US11013764B2
(en)
|
2019-04-30 |
2021-05-25 |
Myeloid Therapeutics, Inc. |
Engineered phagocytic receptor compositions and methods of use thereof
|
|
US20220378824A1
(en)
|
2019-04-30 |
2022-12-01 |
Myeloid Therapeutics, Inc. |
Engineered chimeric fusion protein compositions and methods of use thereof
|
|
MX2021015411A
(es)
|
2019-06-11 |
2022-04-18 |
Myeloid Therapeutics Inc |
Composiciones acopladoras especificas de macrofagos y metodos de uso de las mismas.
|
|
JP2022536951A
(ja)
|
2019-06-19 |
2022-08-22 |
フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー |
環状ポリリボヌクレオチドを投与する方法
|
|
WO2021016075A1
(en)
|
2019-07-19 |
2021-01-28 |
Flagship Pioneering Innovations Vi, Llc |
Recombinase compositions and methods of use
|
|
JP7831937B2
(ja)
|
2019-09-03 |
2026-03-17 |
クリエイト・メディシンズ，インコーポレーテッド |
ゲノム組込みのための方法および組成物
|
|
US20230040216A1
(en)
|
2019-11-19 |
2023-02-09 |
The Broad Institute, Inc. |
Retrotransposons and use thereof
|
|
BR112022011339A2
(pt)
|
2019-12-11 |
2022-10-04 |
Myeloid Therapeutics Inc |
Composições de células terapêuticas e métodos para fabricação e usos das mesmas
|
|
US10980836B1
(en)
|
2019-12-11 |
2021-04-20 |
Myeloid Therapeutics, Inc. |
Therapeutic cell compositions and methods of manufacturing and use thereof
|
|
JP2023516692A
(ja)
|
2020-03-04 |
2023-04-20 |
フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー |
ゲノムを調節するための方法及び組成物
|
|
IL296024A
(en)
|
2020-03-04 |
2022-10-01 |
Flagship Pioneering Innovations Vi Llc |
Methods and compositions for modulating a genome
|
|
CA3174483A1
(en)
|
2020-03-04 |
2021-09-10 |
Flagship Pioneering Innovations Vi, Llc |
Improved methods and compositions for modulating a genome
|
|
AU2021232069A1
(en)
|
2020-03-05 |
2022-11-03 |
Flagship Pioneering Innovations Vi, Llc |
Host defense suppressing methods and compositions for modulating a genome
|
|
CN115867294A
(zh)
|
2020-06-04 |
2023-03-28 |
凯瑞斯马治疗公司 |
嵌合抗原受体的新型构建体
|
|
CA3187138A1
(en)
|
2020-06-26 |
2021-12-30 |
Carisma Therapeutics Inc. |
Mrna transfection of immune cells
|
|
WO2022036265A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim receptors and uses thereof
|
|
AU2021350024A1
(en)
|
2020-09-24 |
2023-05-04 |
Flagship Pioneering Innovations V, Inc. |
Compositions and methods for inhibiting gene expression
|
|
CA3197423A1
(en)
|
2020-11-04 |
2022-05-12 |
Daniel Getts |
Engineered chimeric fusion protein compositions and methods of use thereof
|
|
AU2022272235A1
(en)
|
2021-05-11 |
2023-12-21 |
Create Medicines, Inc. |
Methods and compositions for genomic integration
|