JP2024521444A5 - - Google Patents
Info
- Publication number
- JP2024521444A5 JP2024521444A5 JP2023576064A JP2023576064A JP2024521444A5 JP 2024521444 A5 JP2024521444 A5 JP 2024521444A5 JP 2023576064 A JP2023576064 A JP 2023576064A JP 2023576064 A JP2023576064 A JP 2023576064A JP 2024521444 A5 JP2024521444 A5 JP 2024521444A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- cancer
- sequence
- rna
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163209271P | 2021-06-10 | 2021-06-10 | |
| US63/209,271 | 2021-06-10 | ||
| US202263311923P | 2022-02-18 | 2022-02-18 | |
| US63/311,923 | 2022-02-18 | ||
| PCT/US2022/033091 WO2022261490A2 (en) | 2021-06-10 | 2022-06-10 | Circular rna compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024521444A JP2024521444A (ja) | 2024-05-31 |
| JP2024521444A5 true JP2024521444A5 (https=) | 2025-06-06 |
Family
ID=83081188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023576064A Pending JP2024521444A (ja) | 2021-06-10 | 2022-06-10 | 環状ｒｎａ組成物及び方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250283073A1 (https=) |
| EP (1) | EP4352234A2 (https=) |
| JP (1) | JP2024521444A (https=) |
| KR (1) | KR20240019791A (https=) |
| AU (1) | AU2022288705A1 (https=) |
| BR (1) | BR112023025515A2 (https=) |
| CA (1) | CA3219932A1 (https=) |
| IL (1) | IL308746A (https=) |
| MX (1) | MX2023014702A (https=) |
| TW (1) | TW202317767A (https=) |
| WO (1) | WO2022261490A2 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2024003262A (es) | 2021-09-17 | 2024-06-19 | Flagship Pioneering Innovations Vi Llc | Composiciones y metodos para producir poliribonucleotidos circulares. |
| CN114214237B (zh) * | 2021-12-23 | 2023-06-16 | 南京大学 | 一种洗脱细胞表面吸附纳米颗粒的方法 |
| CN119110847A (zh) * | 2022-01-11 | 2024-12-10 | 北京大学 | 针对sars-cov-2变体的环状rna疫苗及其使用方法 |
| EP4466029A1 (en) * | 2022-01-21 | 2024-11-27 | Orna Therapeutics, Inc. | Systemic administration of circular rna polynucleotides encoding muscle proteins or protein complexes |
| WO2023182948A1 (en) * | 2022-03-21 | 2023-09-28 | Bio Adventure Co., Ltd. | Internal ribosome entry site (ires), plasmid vector and circular mrna for enhancing protein expression |
| US12297285B2 (en) * | 2022-06-24 | 2025-05-13 | Orna Therapeutics, Inc. | Circular RNA encoding chimeric antigen receptors targeting BCMA |
| CN116064531B (zh) * | 2022-09-07 | 2024-04-02 | 昆明理工大学 | 一种抑制cvb5病毒复制的长链非编码rna及应用 |
| WO2024102677A1 (en) | 2022-11-08 | 2024-05-16 | Orna Therapeutics, Inc. | Circular rna compositions |
| AU2023398825A1 (en) | 2022-12-15 | 2025-06-26 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| CN121358494A (zh) | 2023-03-15 | 2026-01-16 | 旗舰创业创新第六有限责任公司 | 免疫原性组合物及其用途 |
| EP4680750A1 (en) | 2023-03-15 | 2026-01-21 | Flagship Pioneering Innovations VI, LLC | Compositions comprising polyribonucleotides and uses thereof |
| KR20240159310A (ko) * | 2023-04-28 | 2024-11-05 | 주식회사 메디치바이오 | 신규한 이온화지질을 이용한 지질나노입자 조성물 |
| WO2024205657A2 (en) * | 2023-03-29 | 2024-10-03 | Orna Therapeutics, Inc. | Lipids and lipid nanoparticle compositions for delivering polynucleotides |
| WO2024200820A1 (en) | 2023-03-30 | 2024-10-03 | Ose Immunotherapeutics | Method of synthesis of targeted lipid nanoparticle and uses thereof |
| EP4687991A1 (en) | 2023-03-30 | 2026-02-11 | Ose Immunotherapeutics | Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof |
| WO2024220752A2 (en) | 2023-04-19 | 2024-10-24 | Sail Biomedicines, Inc. | Rna therapeutic compositions |
| WO2024220625A1 (en) | 2023-04-19 | 2024-10-24 | Sail Biomedicines, Inc. | Delivery of polynucleotides from lipid nanoparticles comprising rna and ionizable lipids |
| WO2024220712A2 (en) | 2023-04-19 | 2024-10-24 | Sail Biomedicines, Inc. | Vaccine compositions |
| EP4705481A2 (en) | 2023-05-05 | 2026-03-11 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025006613A1 (en) * | 2023-06-27 | 2025-01-02 | Hopewell Therapeutics, Inc. | Lipid nanoparticles for cancer immunotherapy |
| WO2025007148A1 (en) | 2023-06-30 | 2025-01-02 | Orna Therapeutics, Inc. | Polymer lipid nanoparticle compositions for delivering circular polynucleotides |
| WO2025036467A1 (en) * | 2023-08-17 | 2025-02-20 | Wuhan University | Circular rna with increased stability and expression |
| WO2025049690A1 (en) | 2023-08-29 | 2025-03-06 | Orna Therapeutics, Inc. | Circular polyethylene glycol lipids |
| AU2024335327A1 (en) | 2023-09-01 | 2026-03-26 | Renagade Therapeutics Management Inc. | Gene editing systems, compositions, and methods for treatment of vexas syndrome |
| WO2025101501A1 (en) | 2023-11-07 | 2025-05-15 | Orna Therapeutics, Inc. | Circular rna compositions |
| WO2025106930A1 (en) | 2023-11-17 | 2025-05-22 | Sail Biomedicines, Inc. | Circular polyribonucleotides encoding glucagon-like peptide 2 (glp-2) and uses thereof |
| WO2025106915A1 (en) | 2023-11-17 | 2025-05-22 | Sail Biomedicines, Inc. | Circular polyribonucleotides encoding glucagon-like peptide 1 (glp-1) and uses thereof |
| WO2025117969A1 (en) | 2023-12-01 | 2025-06-05 | Orna Therapeutics, Inc. | Process for manufacturing lipid nanoparticles |
| WO2025128871A2 (en) | 2023-12-13 | 2025-06-19 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2025133115A1 (en) | 2023-12-21 | 2025-06-26 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising il-35 |
| WO2025149040A1 (zh) * | 2024-01-11 | 2025-07-17 | 深圳近邻生物科技有限公司 | 一种通用的且无"scar"的RNA环化方法 |
| WO2025155753A2 (en) | 2024-01-17 | 2025-07-24 | Renagade Therapeutics Management Inc. | Improved gene editing system, guides, and methods |
| WO2025166238A1 (en) | 2024-01-31 | 2025-08-07 | Orna Therapeutics, Inc. | Fast-shedding polyethylene glycol lipids |
| WO2025179198A1 (en) | 2024-02-23 | 2025-08-28 | Sail Biomedicines, Inc. | Circular polyribonucleotides and unmodified linear rnas with reduced immunogenicity |
| WO2025218812A1 (en) * | 2024-04-19 | 2025-10-23 | Shanghai Circode Biomed Co., Ltd. | Novel internal ribosome entry sites and uses thereof |
| WO2025250751A1 (en) | 2024-05-31 | 2025-12-04 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| CN118703488A (zh) * | 2024-06-20 | 2024-09-27 | 毕昇(北京)生物科技有限公司 | 一种环状rna的纯化方法 |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2026006593A1 (en) | 2024-06-28 | 2026-01-02 | Orna Therapeutics, Inc. | Synthetic internal ribosome entry sites |
| WO2026072709A1 (en) | 2024-09-25 | 2026-04-02 | Orna Therapeutics, Inc. | Chimeric antigen receptors targeting bcma |
| WO2026068705A1 (en) | 2024-09-26 | 2026-04-02 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof |
| CN119876152A (zh) * | 2025-02-10 | 2025-04-25 | 毕昇(北京)生物科技有限公司 | 一种环状rna、嵌合抗原受体t细胞和构建方法及应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6319494B1 (en) | 1990-12-14 | 2001-11-20 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| IL135578A0 (en) | 1997-10-29 | 2001-05-20 | Genzyme Corp | Compositions and methods for treating lysosomal storage disease |
| US5948902A (en) | 1997-11-20 | 1999-09-07 | South Alabama Medical Science Foundation | Antisense oligonucleotides to human serine/threonine protein phosphatase genes |
| WO2001060414A2 (en) | 2000-02-17 | 2001-08-23 | Genzyme Corporation | Genetic modification of the lung as a portal for gene delivery |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| US20040014194A1 (en) | 2002-03-27 | 2004-01-22 | Schering Corporation | Beta-secretase crystals and methods for preparing and using the same |
| ATE475669T1 (de) | 2004-06-29 | 2010-08-15 | Immunocore Ltd | Einen modifizierten t-zellen-rezeptor exprimierende zellen |
| EP3083556B1 (en) | 2013-12-19 | 2019-12-25 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
| JP6948313B6 (ja) | 2015-09-17 | 2022-01-14 | モデルナティエックス インコーポレイテッド | 治療剤の細胞内送達のための化合物および組成物 |
| HRP20230209T1 (hr) | 2015-10-28 | 2023-04-14 | Acuitas Therapeutics Inc. | Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina |
| WO2017222911A1 (en) * | 2016-06-20 | 2017-12-28 | The Board Of Trustees Of The Leland Stanford Junior University | Circular rnas and their use in immunomodulation |
| WO2019081383A1 (en) | 2017-10-25 | 2019-05-02 | Universität Zürich | EUCARYOTE 4 INITIATION FACTOR RECRUITMENT APTAMERS FOR ENHANCED TRANSLATION |
| US20190314291A1 (en) | 2018-01-30 | 2019-10-17 | Modernatx, Inc. | Compositions and methods for delivery of agents to immune cells |
| MX2020007944A (es) | 2018-02-01 | 2020-11-24 | Tufts College | Nanocomplejos similares a los lípidos y sus usos. |
| WO2019191780A1 (en) | 2018-03-30 | 2019-10-03 | Arcturus Therapeutics, Inc. | Lipid particles for nucleic acid delivery |
| CN112399860B (zh) * | 2018-06-06 | 2024-08-16 | 麻省理工学院 | 用于在真核细胞中翻译的环状rna |
| BR112021023411A2 (pt) * | 2019-05-22 | 2022-02-01 | Massachusetts Inst Technology | Composições e métodos de rna circular |
-
2022
- 2022-06-10 TW TW111121745A patent/TW202317767A/zh unknown
- 2022-06-10 MX MX2023014702A patent/MX2023014702A/es unknown
- 2022-06-10 WO PCT/US2022/033091 patent/WO2022261490A2/en not_active Ceased
- 2022-06-10 EP EP22760801.5A patent/EP4352234A2/en active Pending
- 2022-06-10 US US18/567,469 patent/US20250283073A1/en active Pending
- 2022-06-10 JP JP2023576064A patent/JP2024521444A/ja active Pending
- 2022-06-10 KR KR1020247000046A patent/KR20240019791A/ko active Pending
- 2022-06-10 IL IL308746A patent/IL308746A/en unknown
- 2022-06-10 BR BR112023025515A patent/BR112023025515A2/pt unknown
- 2022-06-10 CA CA3219932A patent/CA3219932A1/en active Pending
- 2022-06-10 AU AU2022288705A patent/AU2022288705A1/en active Pending
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