JP2020040952A5 - - Google Patents
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- Publication number
- JP2020040952A5 JP2020040952A5 JP2019193276A JP2019193276A JP2020040952A5 JP 2020040952 A5 JP2020040952 A5 JP 2020040952A5 JP 2019193276 A JP2019193276 A JP 2019193276A JP 2019193276 A JP2019193276 A JP 2019193276A JP 2020040952 A5 JP2020040952 A5 JP 2020040952A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- membrane
- chromatography
- ion exchange
- exchange membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021102974A JP7359807B2 (ja) | 2011-12-22 | 2021-06-22 | イオン交換膜クロマトグラフィー |
| JP2022050501A JP2022101557A (ja) | 2011-12-22 | 2022-03-25 | イオン交換膜クロマトグラフィー |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579285P | 2011-12-22 | 2011-12-22 | |
| US61/579,285 | 2011-12-22 | ||
| JP2018023128A JP2018109024A (ja) | 2011-12-22 | 2018-02-13 | イオン交換膜クロマトグラフィー |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018023128A Division JP2018109024A (ja) | 2011-12-22 | 2018-02-13 | イオン交換膜クロマトグラフィー |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021102974A Division JP7359807B2 (ja) | 2011-12-22 | 2021-06-22 | イオン交換膜クロマトグラフィー |
| JP2022050501A Division JP2022101557A (ja) | 2011-12-22 | 2022-03-25 | イオン交換膜クロマトグラフィー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020040952A JP2020040952A (ja) | 2020-03-19 |
| JP2020040952A5 true JP2020040952A5 (enExample) | 2021-09-09 |
| JP7402011B2 JP7402011B2 (ja) | 2023-12-20 |
Family
ID=47430154
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014549204A Active JP6605202B2 (ja) | 2011-12-22 | 2012-12-18 | イオン交換膜クロマトグラフィー |
| JP2018023128A Withdrawn JP2018109024A (ja) | 2011-12-22 | 2018-02-13 | イオン交換膜クロマトグラフィー |
| JP2019193276A Active JP7402011B2 (ja) | 2011-12-22 | 2019-10-24 | イオン交換膜クロマトグラフィー |
| JP2021102974A Active JP7359807B2 (ja) | 2011-12-22 | 2021-06-22 | イオン交換膜クロマトグラフィー |
| JP2022050501A Pending JP2022101557A (ja) | 2011-12-22 | 2022-03-25 | イオン交換膜クロマトグラフィー |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014549204A Active JP6605202B2 (ja) | 2011-12-22 | 2012-12-18 | イオン交換膜クロマトグラフィー |
| JP2018023128A Withdrawn JP2018109024A (ja) | 2011-12-22 | 2018-02-13 | イオン交換膜クロマトグラフィー |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021102974A Active JP7359807B2 (ja) | 2011-12-22 | 2021-06-22 | イオン交換膜クロマトグラフィー |
| JP2022050501A Pending JP2022101557A (ja) | 2011-12-22 | 2022-03-25 | イオン交換膜クロマトグラフィー |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US10364268B2 (enExample) |
| EP (2) | EP3492486A1 (enExample) |
| JP (5) | JP6605202B2 (enExample) |
| KR (3) | KR20210025692A (enExample) |
| CN (2) | CN108892706A (enExample) |
| AR (1) | AR089362A1 (enExample) |
| AU (3) | AU2012355356B2 (enExample) |
| BR (1) | BR112014015101A8 (enExample) |
| CA (1) | CA2859376C (enExample) |
| ES (1) | ES2697676T3 (enExample) |
| HR (1) | HRP20181846T1 (enExample) |
| IL (2) | IL267585B (enExample) |
| MX (2) | MX360453B (enExample) |
| MY (1) | MY172426A (enExample) |
| PL (1) | PL2794635T3 (enExample) |
| RU (1) | RU2648999C2 (enExample) |
| SG (1) | SG11201403437TA (enExample) |
| SI (1) | SI2794635T1 (enExample) |
| TR (1) | TR201815709T4 (enExample) |
| WO (1) | WO2013096322A1 (enExample) |
| ZA (2) | ZA201404593B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL267585B (en) * | 2011-12-22 | 2022-09-01 | Genentech Inc | Ion exchange membrane chromatography |
| CN110054661A (zh) | 2013-12-12 | 2019-07-26 | Emd密理博公司 | 使用含丙烯酰胺的过滤器分离蛋白 |
| CN106029682B (zh) | 2013-12-27 | 2021-04-13 | 中外制药株式会社 | 等电点低的抗体的纯化方法 |
| CN104693303B (zh) * | 2015-02-28 | 2018-03-13 | 苏州金盟生物技术有限公司 | 一种蛋白制品中的核酸去除方法 |
| EP3334747B1 (en) | 2015-08-13 | 2023-09-27 | Amgen Inc. | Charged depth filtration of antigen-binding proteins |
| GB201711481D0 (en) | 2017-07-17 | 2017-08-30 | Ucb Biopharma Sprl | Protein purification |
| EP3546475A1 (en) * | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
| US10792618B2 (en) | 2018-06-19 | 2020-10-06 | Sartorius Stedim Biotech Gmbh | Particle separation and/or purification of a fluid |
| KR102140531B1 (ko) * | 2018-08-07 | 2020-08-04 | (주)휴온스 | Gly-Tβ4의 제조방법 |
| EP3837273B1 (en) * | 2018-08-14 | 2025-09-24 | Bristol-Myers Squibb Company | Improved protein recovery |
| GB201815405D0 (en) * | 2018-09-21 | 2018-11-07 | Fujifilm Mfg Europe Bv | Membranes suitable for detecting, filtering and/or purifying biomolecules |
| US12306152B2 (en) | 2018-12-21 | 2025-05-20 | Solventum Intellectual Properties Company | Method for testing a chromatography device used for ion exchange |
| AR119264A1 (es) * | 2019-06-05 | 2021-12-09 | Genentech Inc | Método para reutilización de cromatografía |
| CN115335394A (zh) * | 2020-01-24 | 2022-11-11 | 奥克梅斯制药爱尔兰有限公司 | 纯化方法 |
| US11416468B2 (en) * | 2020-07-21 | 2022-08-16 | International Business Machines Corporation | Active-active system index management |
| CN116371011B (zh) * | 2023-05-26 | 2023-08-18 | 湖南杰萃生物技术有限公司 | 一种从桑叶中提取黄酮和生物碱的方法 |
| CN117866038B (zh) * | 2024-03-11 | 2024-05-28 | 北京百力格生物科技有限公司 | 纯化含有宿主核酸的带亲和标签的酸性蛋白的方法 |
Family Cites Families (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE266710C (enExample) | ||||
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4515893A (en) | 1979-04-26 | 1985-05-07 | Ortho Pharmaceutical Corporation | Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| JPS6150925A (ja) | 1984-08-17 | 1986-03-13 | Toray Ind Inc | 抗原または抗体の精製方法 |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US5091178A (en) | 1986-02-21 | 1992-02-25 | Oncogen | Tumor therapy with biologically active anti-tumor antibodies |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| EP0391934A1 (en) * | 1987-10-23 | 1990-10-17 | Schering Corporation | Method of purifying protein |
| US5091313A (en) | 1988-08-05 | 1992-02-25 | Tanox Biosystems, Inc. | Antigenic epitopes of IgE present on B cell but not basophil surface |
| US5720937A (en) | 1988-01-12 | 1998-02-24 | Genentech, Inc. | In vivo tumor detection assay |
| WO1989012463A1 (en) | 1988-06-21 | 1989-12-28 | Genentech, Inc. | Method and therapeutic compositions for the treatment of myocardial infarction |
| EP0435911B1 (en) | 1988-09-23 | 1996-03-13 | Cetus Oncology Corporation | Cell culture medium for enhanced cell growth, culture longevity and product expression |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| JP2844346B2 (ja) | 1989-05-31 | 1999-01-06 | 昭 梶 | 新規ペプチドならびに新規ｄｎａ |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| ES2193136T3 (es) | 1991-08-14 | 2003-11-01 | Genentech Inc | Variantes de inmunoglubina para receptores especificos de fc epsilon. |
| AU3178993A (en) | 1991-11-25 | 1993-06-28 | Enzon, Inc. | Multivalent antigen-binding proteins |
| ATE419355T1 (de) | 1992-02-06 | 2009-01-15 | Novartis Vaccines & Diagnostic | Marker für krebs und biosynthetisches bindeprotein dafür |
| EP0656789B1 (en) | 1992-08-21 | 1997-12-17 | Genentech, Inc. | Method for treating a lfa-1-mediated disorder |
| US5736137A (en) | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| US5595721A (en) | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| DE69416103T2 (de) | 1993-09-21 | 1999-08-05 | Hemosol Inc., Etobicoke, Ontario | Verdrängungschromatographisches verfahren und gereinigtes hämoglobin |
| US5714338A (en) | 1993-12-10 | 1998-02-03 | Genentech, Inc. | Methods for diagnosis of allergy |
| EP0739214B1 (en) | 1994-01-18 | 1998-03-18 | Genentech, Inc. | A METHOD OF TREATMENT OF PARASITIC INFECTION USING IgE ANTAGONISTS |
| EP0749488A1 (en) | 1994-03-03 | 1996-12-27 | Genentech, Inc. | Anti-il-8 monoclonal antibodies for treatment of inflammatory disorders |
| US5534615A (en) | 1994-04-25 | 1996-07-09 | Genentech, Inc. | Cardiac hypertrophy factor and uses therefor |
| IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
| US5641870A (en) * | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| AU6267896A (en) | 1995-06-07 | 1996-12-30 | Imclone Systems Incorporated | Antibody and antibody fragments for inhibiting the growth oftumors |
| EP1297847A3 (en) | 1996-01-23 | 2003-05-07 | Genentech, Inc. | Anti-CD18 antibodies in stroke |
| US6592905B1 (en) | 1996-01-31 | 2003-07-15 | Massey University | Production of an immunoglobulin enriched fraction from whey protein solutions |
| US7147851B1 (en) | 1996-08-15 | 2006-12-12 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with α4β7 integrin |
| KR100532178B1 (ko) | 1996-11-27 | 2005-12-01 | 제넨테크, 인크. | 인간화 항-ＣＤ11ａ 항체 |
| ES2236634T3 (es) | 1997-04-07 | 2005-07-16 | Genentech, Inc. | Anticuerpos anti-vegf. |
| ES2293682T5 (es) | 1997-05-15 | 2011-11-17 | Genentech, Inc. | Anticuerpo anti-apo2. |
| US6054293A (en) | 1997-07-08 | 2000-04-25 | The Regents Of The University Of California | Semaphorin receptors |
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| GEP20104998B (en) | 1999-06-25 | 2010-06-10 | Genentech Inc | Humanized antibody which binds erbb2 and blocks activation by ligand receptor of erbb2 (variants) and use of the composition comprising these antibodies methods for treating cancer |
| DK1226177T3 (da) | 1999-10-29 | 2008-10-06 | Genentech Inc | Antistofsammensætninger mod anti-prostata stamcelle-antigen (PSCA) og anvendelser deraf |
| US20020012982A1 (en) | 2000-07-13 | 2002-01-31 | Invitrogen Corporation | Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix |
| UA83458C2 (uk) | 2000-09-18 | 2008-07-25 | Байоджен Айдек Ма Інк. | Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf) |
| US7321026B2 (en) | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
| WO2003025156A2 (en) | 2001-09-18 | 2003-03-27 | Affinium Pharmaceuticals, Inc. | Methods and apparatuses for purification |
| AU2002332130A1 (en) | 2001-10-16 | 2003-04-28 | Exelixis, Inc. | Msrebps as modifiers of the srebp pathway and methods of use |
| WO2003033658A2 (en) | 2001-10-17 | 2003-04-24 | Human Genome Sciences, Inc. | Neutrokine-alpha and neutrokine-alpha splice variant |
| US20040093621A1 (en) | 2001-12-25 | 2004-05-13 | Kyowa Hakko Kogyo Co., Ltd | Antibody composition which specifically binds to CD20 |
| CN100522999C (zh) | 2002-02-14 | 2009-08-05 | 免疫医疗公司 | 抗cd20抗体及其融合蛋白和使用方法 |
| WO2004035607A2 (en) | 2002-10-17 | 2004-04-29 | Genmab A/S | Human monoclonal antibodies against cd20 |
| PT1572744E (pt) | 2002-12-16 | 2010-09-07 | Genentech Inc | Variantes de imunoglobulina e utilizações destas |
| CN1206240C (zh) * | 2003-04-07 | 2005-06-15 | 中国科学院生态环境研究中心 | 高效离子交换膜色谱纯化卵黄蛋白原技术 |
| NZ543960A (en) | 2003-05-09 | 2008-11-28 | Univ Duke | CD20-specific antibodies and methods of employing same |
| AR044388A1 (es) | 2003-05-20 | 2005-09-07 | Applied Molecular Evolution | Moleculas de union a cd20 |
| JP4818917B2 (ja) | 2003-08-08 | 2011-11-16 | イミューノメディクス、インコーポレイテッド | 腫瘍および罹患細胞のアポトーシスを誘発するための二重特異性抗体 |
| US8147832B2 (en) | 2003-08-14 | 2012-04-03 | Merck Patent Gmbh | CD20-binding polypeptide compositions and methods |
| US20080274501A1 (en) * | 2007-05-02 | 2008-11-06 | Chenming Zhang | Method of purifying acidic proteins expressed in plants |
| US9433922B2 (en) | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
| US8653246B2 (en) | 2007-10-26 | 2014-02-18 | Asahi Kasei Chemicals Corporation | Method for purifying protein |
| CL2008003218A1 (es) | 2007-10-30 | 2009-03-06 | Genentech Inc | Método para la purificación de un anticuerpo a partir de una composición que comprende el anticuerpo y al menos un contaminante. |
| WO2009135656A1 (en) * | 2008-05-06 | 2009-11-12 | Lonza Biologics Plc. | A method for the purification of antibodies using displacement chromatography |
| KR101843915B1 (ko) | 2008-08-14 | 2018-04-02 | 제넨테크, 인크. | 고유 단백질 대체 이온 교환 막 크로마토그래피를 이용한 오염물의 제거 방법 |
| GB0816242D0 (en) | 2008-09-05 | 2008-10-15 | Immunobiology Ltd | Method of purifying protien complexes |
| KR101844859B1 (ko) | 2009-08-06 | 2018-05-18 | 제넨테크, 인크. | 단백질 정제 시의 바이러스 제거의 개선방법 |
| CA2772653C (en) * | 2009-09-01 | 2019-06-25 | Genentech, Inc. | Enhanced protein purification through a modified protein a elution |
| DK2560683T4 (da) * | 2010-04-23 | 2022-08-29 | Hoffmann La Roche | Fremstilling af heteromultimeriske proteiner |
| MY161534A (en) | 2010-05-25 | 2017-04-28 | Genentech Inc | Methods of purifying polypeptides |
| KR20140084125A (ko) * | 2011-10-03 | 2014-07-04 | 사켐,인코포레이티드 | 소수성 치환 크로마토그래피용 중성 양쪽성 이온 디스플레이서 분자 |
| IL267585B (en) | 2011-12-22 | 2022-09-01 | Genentech Inc | Ion exchange membrane chromatography |
| JP5731726B1 (ja) | 2014-06-26 | 2015-06-10 | 楽天株式会社 | 情報処理装置、情報処理方法及び情報処理プログラム |
-
2012
- 2012-12-18 IL IL267585A patent/IL267585B/en unknown
- 2012-12-18 EP EP18193475.3A patent/EP3492486A1/en active Pending
- 2012-12-18 SI SI201231443T patent/SI2794635T1/sl unknown
- 2012-12-18 SG SG11201403437TA patent/SG11201403437TA/en unknown
- 2012-12-18 KR KR1020217005616A patent/KR20210025692A/ko not_active Ceased
- 2012-12-18 PL PL12806322T patent/PL2794635T3/pl unknown
- 2012-12-18 BR BR112014015101A patent/BR112014015101A8/pt not_active Application Discontinuation
- 2012-12-18 WO PCT/US2012/070373 patent/WO2013096322A1/en not_active Ceased
- 2012-12-18 MY MYPI2014701665A patent/MY172426A/en unknown
- 2012-12-18 CN CN201810818291.3A patent/CN108892706A/zh active Pending
- 2012-12-18 MX MX2014007622A patent/MX360453B/es active IP Right Grant
- 2012-12-18 EP EP12806322.9A patent/EP2794635B8/en active Active
- 2012-12-18 US US14/365,449 patent/US10364268B2/en active Active
- 2012-12-18 AU AU2012355356A patent/AU2012355356B2/en active Active
- 2012-12-18 CA CA2859376A patent/CA2859376C/en active Active
- 2012-12-18 KR KR1020147019968A patent/KR102067075B1/ko active Active
- 2012-12-18 ES ES12806322T patent/ES2697676T3/es active Active
- 2012-12-18 TR TR2018/15709T patent/TR201815709T4/tr unknown
- 2012-12-18 JP JP2014549204A patent/JP6605202B2/ja active Active
- 2012-12-18 KR KR1020207000846A patent/KR20200008022A/ko not_active Ceased
- 2012-12-18 HR HRP20181846TT patent/HRP20181846T1/hr unknown
- 2012-12-18 CN CN201280070369.9A patent/CN104125963B/zh active Active
- 2012-12-18 RU RU2014130017A patent/RU2648999C2/ru active
- 2012-12-20 AR ARP120104862A patent/AR089362A1/es not_active Application Discontinuation
-
2014
- 2014-06-16 IL IL233158A patent/IL233158B/en active IP Right Grant
- 2014-06-20 MX MX2018013356A patent/MX2018013356A/es unknown
- 2014-06-23 ZA ZA2014/04593A patent/ZA201404593B/en unknown
-
2018
- 2018-01-10 AU AU2018200194A patent/AU2018200194B2/en active Active
- 2018-02-13 JP JP2018023128A patent/JP2018109024A/ja not_active Withdrawn
-
2019
- 2019-06-06 US US16/433,763 patent/US11945837B2/en active Active
- 2019-06-20 ZA ZA2019/03994A patent/ZA201903994B/en unknown
- 2019-10-24 JP JP2019193276A patent/JP7402011B2/ja active Active
-
2020
- 2020-02-14 AU AU2020201070A patent/AU2020201070A1/en not_active Abandoned
-
2021
- 2021-06-22 JP JP2021102974A patent/JP7359807B2/ja active Active
-
2022
- 2022-03-25 JP JP2022050501A patent/JP2022101557A/ja active Pending
-
2024
- 2024-03-01 US US18/593,665 patent/US20240247027A1/en active Pending
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