ES2697676T3 - Cromatografía de membrana de intercambio iónico - Google Patents
Cromatografía de membrana de intercambio iónico Download PDFInfo
- Publication number
- ES2697676T3 ES2697676T3 ES12806322T ES12806322T ES2697676T3 ES 2697676 T3 ES2697676 T3 ES 2697676T3 ES 12806322 T ES12806322 T ES 12806322T ES 12806322 T ES12806322 T ES 12806322T ES 2697676 T3 ES2697676 T3 ES 2697676T3
- Authority
- ES
- Spain
- Prior art keywords
- antibody
- membrane
- ion exchange
- antibodies
- interest
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579285P | 2011-12-22 | 2011-12-22 | |
| PCT/US2012/070373 WO2013096322A1 (en) | 2011-12-22 | 2012-12-18 | Ion exchange membrane chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2697676T3 true ES2697676T3 (es) | 2019-01-25 |
Family
ID=47430154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12806322T Active ES2697676T3 (es) | 2011-12-22 | 2012-12-18 | Cromatografía de membrana de intercambio iónico |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US10364268B2 (enExample) |
| EP (2) | EP3492486A1 (enExample) |
| JP (5) | JP6605202B2 (enExample) |
| KR (3) | KR20200008022A (enExample) |
| CN (2) | CN104125963B (enExample) |
| AR (1) | AR089362A1 (enExample) |
| AU (3) | AU2012355356B2 (enExample) |
| BR (1) | BR112014015101A8 (enExample) |
| CA (1) | CA2859376C (enExample) |
| ES (1) | ES2697676T3 (enExample) |
| HR (1) | HRP20181846T1 (enExample) |
| IL (2) | IL267585B (enExample) |
| MX (2) | MX360453B (enExample) |
| MY (1) | MY172426A (enExample) |
| PL (1) | PL2794635T3 (enExample) |
| RU (1) | RU2648999C2 (enExample) |
| SG (1) | SG11201403437TA (enExample) |
| SI (1) | SI2794635T1 (enExample) |
| TR (1) | TR201815709T4 (enExample) |
| WO (1) | WO2013096322A1 (enExample) |
| ZA (2) | ZA201404593B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20181846T1 (hr) | 2011-12-22 | 2018-12-28 | Genentech, Inc. | Kromatografija membranom za ionsku izmjenu |
| KR101891522B1 (ko) | 2013-12-12 | 2018-08-24 | 이엠디 밀리포어 코포레이션 | 아크릴아미드 함유 필터를 사용한 단백질 분리 |
| EP3088411B1 (en) * | 2013-12-27 | 2025-09-24 | Chugai Seiyaku Kabushiki Kaisha | Method for purifying antibody having low isoelectric point |
| CN104693303B (zh) * | 2015-02-28 | 2018-03-13 | 苏州金盟生物技术有限公司 | 一种蛋白制品中的核酸去除方法 |
| DK3334747T5 (da) | 2015-08-13 | 2024-10-07 | Amgen Inc | Ladet dybdefiltrering af antigenbindende proteiner |
| GB201711481D0 (en) | 2017-07-17 | 2017-08-30 | Ucb Biopharma Sprl | Protein purification |
| EP3546475A1 (en) * | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
| US10792618B2 (en) | 2018-06-19 | 2020-10-06 | Sartorius Stedim Biotech Gmbh | Particle separation and/or purification of a fluid |
| KR102140531B1 (ko) * | 2018-08-07 | 2020-08-04 | (주)휴온스 | Gly-Tβ4의 제조방법 |
| PT3837273T (pt) * | 2018-08-14 | 2025-12-26 | Bristol Myers Squibb Co | Recuperação melhorada de proteínas |
| GB201815405D0 (en) * | 2018-09-21 | 2018-11-07 | Fujifilm Mfg Europe Bv | Membranes suitable for detecting, filtering and/or purifying biomolecules |
| WO2020128797A1 (en) * | 2018-12-21 | 2020-06-25 | 3M Innovative Properties Company | Method for testing a chromatography device used for ion exchange |
| AR119264A1 (es) * | 2019-06-05 | 2021-12-09 | Genentech Inc | Método para reutilización de cromatografía |
| MX2022009134A (es) * | 2020-01-24 | 2022-10-21 | Alkermes Pharma Ireland Ltd | Metodos de purificacion. |
| US11416468B2 (en) * | 2020-07-21 | 2022-08-16 | International Business Machines Corporation | Active-active system index management |
| CN116371011B (zh) * | 2023-05-26 | 2023-08-18 | 湖南杰萃生物技术有限公司 | 一种从桑叶中提取黄酮和生物碱的方法 |
| CN117866038B (zh) * | 2024-03-11 | 2024-05-28 | 北京百力格生物科技有限公司 | 纯化含有宿主核酸的带亲和标签的酸性蛋白的方法 |
Family Cites Families (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE266710C (enExample) | ||||
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4515893A (en) | 1979-04-26 | 1985-05-07 | Ortho Pharmaceutical Corporation | Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| JPS6150925A (ja) * | 1984-08-17 | 1986-03-13 | Toray Ind Inc | 抗原または抗体の精製方法 |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US5091178A (en) | 1986-02-21 | 1992-02-25 | Oncogen | Tumor therapy with biologically active anti-tumor antibodies |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| JPH0788395B2 (ja) * | 1987-10-23 | 1995-09-27 | シェリング・コーポレーション | タンパク質の精製方法 |
| US5091313A (en) | 1988-08-05 | 1992-02-25 | Tanox Biosystems, Inc. | Antigenic epitopes of IgE present on B cell but not basophil surface |
| US5720937A (en) | 1988-01-12 | 1998-02-24 | Genentech, Inc. | In vivo tumor detection assay |
| EP0420937B1 (en) | 1988-06-21 | 1994-11-09 | Genentech, Inc. | Therapeutic compositions for the treatment of myocardial infarction |
| DE68925971T2 (de) | 1988-09-23 | 1996-09-05 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| JP2844346B2 (ja) * | 1989-05-31 | 1999-01-06 | 昭 梶 | 新規ペプチドならびに新規dna |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| ATE233813T1 (de) | 1991-08-14 | 2003-03-15 | Genentech Inc | Veränderte immunglobuline für spezifische fc- epsilon rezeptoren |
| ATE297465T1 (de) | 1991-11-25 | 2005-06-15 | Enzon Inc | Verfahren zur herstellung von multivalenten antigenbindenden proteinen |
| ATE503496T1 (de) | 1992-02-06 | 2011-04-15 | Novartis Vaccines & Diagnostic | Biosynthetisches bindeprotein für tumormarker |
| JPH08500826A (ja) | 1992-08-21 | 1996-01-30 | ジェネンテク,インコーポレイテッド | Lfa−1仲介疾患を処置する方法 |
| US5736137A (en) | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| US5595721A (en) | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| HU218159B (hu) | 1993-09-21 | 2000-06-28 | Hemosol Inc. | Kiszorításos kromatográfiás eljárás tisztított hemoglobintermék előállítására |
| US5714338A (en) | 1993-12-10 | 1998-02-03 | Genentech, Inc. | Methods for diagnosis of allergy |
| EP0739214B1 (en) | 1994-01-18 | 1998-03-18 | Genentech, Inc. | A METHOD OF TREATMENT OF PARASITIC INFECTION USING IgE ANTAGONISTS |
| CA2181787A1 (en) | 1994-03-03 | 1995-09-08 | Claire M. Doerschuk | Anti-il-8 monoclonal antibodies for treatment of inflammatory disorders |
| US5534615A (en) | 1994-04-25 | 1996-07-09 | Genentech, Inc. | Cardiac hypertrophy factor and uses therefor |
| IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| EP0831880A4 (en) | 1995-06-07 | 2004-12-01 | Imclone Systems Inc | ANTIBODIES AND FRAGMENTS OF ANTIBODIES INHIBITING TUMOR GROWTH |
| ES2183131T3 (es) | 1996-01-23 | 2003-03-16 | Genentech Inc | Anticuerpos anti-cd18 utilizados contra el ictus cerebral. |
| AU1458497A (en) * | 1996-01-31 | 1997-08-22 | John Stephen Ayers | Production of an immunoglobulin enriched fraction from whey protein solutions |
| US7147851B1 (en) | 1996-08-15 | 2006-12-12 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with α4β7 integrin |
| IL130143A0 (en) | 1996-11-27 | 2000-06-01 | Genentech Inc | Humanized anti-CD11a antibodies |
| DE69836729T2 (de) | 1997-04-07 | 2007-12-13 | Genentech, Inc., South San Francisco | Anti-vefg antibodies |
| PT981618E (pt) | 1997-05-15 | 2007-11-23 | Genentech Inc | ''anticorpo anti-apo-2'' |
| US6054293A (en) | 1997-07-08 | 2000-04-25 | The Regents Of The University Of California | Semaphorin receptors |
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| NZ516830A (en) | 1999-06-25 | 2004-07-30 | Genentech Inc | Humanized anti-ErbB2 antibodies conjugated with a cytotoxic or chemotherapeutic agent for treating cancer |
| CN1413220A (zh) | 1999-10-29 | 2003-04-23 | 杰南技术公司 | 抗前列腺干细胞抗原(psca)抗体组合物及其应用方法 |
| WO2002006456A1 (en) * | 2000-07-13 | 2002-01-24 | Invitrogen Corporation | Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix |
| UA83458C2 (uk) | 2000-09-18 | 2008-07-25 | Байоджен Айдек Ма Інк. | Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf) |
| US7321026B2 (en) | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
| US20030170810A1 (en) | 2001-09-18 | 2003-09-11 | Masoud Vedadi | Methods and apparatuses for purification |
| AU2002332130A1 (en) | 2001-10-16 | 2003-04-28 | Exelixis, Inc. | Msrebps as modifiers of the srebp pathway and methods of use |
| CA2476675A1 (en) | 2001-10-17 | 2003-04-24 | Human Genome Sciences, Inc. | Neutrokine-alpha and neutrokine-alpha splice variant |
| US20040093621A1 (en) | 2001-12-25 | 2004-05-13 | Kyowa Hakko Kogyo Co., Ltd | Antibody composition which specifically binds to CD20 |
| EP1519959B1 (en) | 2002-02-14 | 2014-04-02 | Immunomedics, Inc. | Anti-cd20 antibodies and fusion proteins thereof and methods of use |
| ATE540978T1 (de) | 2002-10-17 | 2012-01-15 | Genmab As | Humane monoklonale antikörper gegen cd20 |
| BRPI0316779B1 (pt) | 2002-12-16 | 2020-04-28 | Genentech Inc | anticorpo humanizado que liga cd20 humano, composição, artigo manufaturado, método de indução da apoptose, método de tratamento de câncer cd20 positivo, métodos de tratamento de doenças autoimunes, ácidos nucléicos isolados, vetores de expressão, células hospedeiras, método para a produção de um anticorpo 2h7 humanizado, polipeptídeo isolado, formulação líquida, método de tratamento de artrite reumatóide (ra) e anticorpos de ligação de cd20 humanizados |
| CN1206240C (zh) * | 2003-04-07 | 2005-06-15 | 中国科学院生态环境研究中心 | 高效离子交换膜色谱纯化卵黄蛋白原技术 |
| JP5416338B2 (ja) | 2003-05-09 | 2014-02-12 | デューク ユニバーシティ | Cd20特異的抗体およびその使用方法 |
| AR044388A1 (es) | 2003-05-20 | 2005-09-07 | Applied Molecular Evolution | Moleculas de union a cd20 |
| US20050079184A1 (en) | 2003-08-08 | 2005-04-14 | Immunomedics, Inc. | Bispecific antibodies for inducing apoptosis of tumor and diseased cells |
| US8147832B2 (en) | 2003-08-14 | 2012-04-03 | Merck Patent Gmbh | CD20-binding polypeptide compositions and methods |
| US20080274501A1 (en) * | 2007-05-02 | 2008-11-06 | Chenming Zhang | Method of purifying acidic proteins expressed in plants |
| US9433922B2 (en) | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
| AU2008315124B2 (en) | 2007-10-26 | 2012-06-21 | Asahi Kasei Chemicals Corporation | Method for purifying protein |
| PL2215117T5 (pl) | 2007-10-30 | 2018-06-29 | Genentech, Inc. | Oczyszczanie przeciwciał za pomocą chromatografii kationowymiennej |
| WO2009135656A1 (en) * | 2008-05-06 | 2009-11-12 | Lonza Biologics Plc. | A method for the purification of antibodies using displacement chromatography |
| PT2848625T (pt) | 2008-08-14 | 2019-10-25 | Genentech Inc | Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena. |
| GB0816242D0 (en) | 2008-09-05 | 2008-10-15 | Immunobiology Ltd | Method of purifying protien complexes |
| NO2462158T3 (enExample) | 2009-08-06 | 2018-06-09 | ||
| CN108409829A (zh) * | 2009-09-01 | 2018-08-17 | 弗·哈夫曼-拉罗切有限公司 | 通过改进的a蛋白洗脱增强的蛋白质纯化 |
| CN102946906B (zh) * | 2010-04-23 | 2015-07-15 | 弗·哈夫曼-拉罗切有限公司 | 生产异源多聚体蛋白质 |
| HRP20241463T1 (hr) | 2010-05-25 | 2025-01-03 | F. Hoffmann - La Roche Ag | Metode pročišćavanja polipeptida |
| CA2850765A1 (en) * | 2011-10-03 | 2013-04-11 | Sachem, Inc. | Anionic displacer molecules for hydrophobic displacement chromatography |
| HRP20181846T1 (hr) | 2011-12-22 | 2018-12-28 | Genentech, Inc. | Kromatografija membranom za ionsku izmjenu |
| US9813410B2 (en) | 2014-06-26 | 2017-11-07 | Rakuten, Inc. | Information processing apparatus, information processing method, and information processing program |
-
2012
- 2012-12-18 HR HRP20181846TT patent/HRP20181846T1/hr unknown
- 2012-12-18 BR BR112014015101A patent/BR112014015101A8/pt not_active Application Discontinuation
- 2012-12-18 EP EP18193475.3A patent/EP3492486A1/en active Pending
- 2012-12-18 US US14/365,449 patent/US10364268B2/en active Active
- 2012-12-18 CN CN201280070369.9A patent/CN104125963B/zh active Active
- 2012-12-18 KR KR1020207000846A patent/KR20200008022A/ko not_active Ceased
- 2012-12-18 MX MX2014007622A patent/MX360453B/es active IP Right Grant
- 2012-12-18 CN CN201810818291.3A patent/CN108892706A/zh active Pending
- 2012-12-18 TR TR2018/15709T patent/TR201815709T4/tr unknown
- 2012-12-18 CA CA2859376A patent/CA2859376C/en active Active
- 2012-12-18 MY MYPI2014701665A patent/MY172426A/en unknown
- 2012-12-18 ES ES12806322T patent/ES2697676T3/es active Active
- 2012-12-18 IL IL267585A patent/IL267585B/en unknown
- 2012-12-18 EP EP12806322.9A patent/EP2794635B8/en active Active
- 2012-12-18 KR KR1020217005616A patent/KR20210025692A/ko not_active Ceased
- 2012-12-18 JP JP2014549204A patent/JP6605202B2/ja active Active
- 2012-12-18 AU AU2012355356A patent/AU2012355356B2/en active Active
- 2012-12-18 RU RU2014130017A patent/RU2648999C2/ru active
- 2012-12-18 SG SG11201403437TA patent/SG11201403437TA/en unknown
- 2012-12-18 KR KR1020147019968A patent/KR102067075B1/ko active Active
- 2012-12-18 SI SI201231443T patent/SI2794635T1/sl unknown
- 2012-12-18 PL PL12806322T patent/PL2794635T3/pl unknown
- 2012-12-18 WO PCT/US2012/070373 patent/WO2013096322A1/en not_active Ceased
- 2012-12-20 AR ARP120104862A patent/AR089362A1/es not_active Application Discontinuation
-
2014
- 2014-06-16 IL IL233158A patent/IL233158B/en active IP Right Grant
- 2014-06-20 MX MX2018013356A patent/MX2018013356A/es unknown
- 2014-06-23 ZA ZA2014/04593A patent/ZA201404593B/en unknown
-
2018
- 2018-01-10 AU AU2018200194A patent/AU2018200194B2/en active Active
- 2018-02-13 JP JP2018023128A patent/JP2018109024A/ja not_active Withdrawn
-
2019
- 2019-06-06 US US16/433,763 patent/US11945837B2/en active Active
- 2019-06-20 ZA ZA2019/03994A patent/ZA201903994B/en unknown
- 2019-10-24 JP JP2019193276A patent/JP7402011B2/ja active Active
-
2020
- 2020-02-14 AU AU2020201070A patent/AU2020201070A1/en not_active Abandoned
-
2021
- 2021-06-22 JP JP2021102974A patent/JP7359807B2/ja active Active
-
2022
- 2022-03-25 JP JP2022050501A patent/JP2022101557A/ja active Pending
-
2024
- 2024-03-01 US US18/593,665 patent/US20240247027A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2697676T3 (es) | Cromatografía de membrana de intercambio iónico | |
| ES2978373T3 (es) | Métodos para eliminar un contaminante usando cromatografía de membrana de intercambio iónico de desplazamiento de proteínas indígenas | |
| HK40006174A (en) | Methods of enhancing efficiency of downstream chromatography steps for purification of proteins using ion exchange membrane chromatography | |
| HK1203526B (zh) | 使用离子交换膜层析改进下游蛋白质纯化步骤的方法 | |
| NZ626949B2 (en) | Ion exchange membrane chromatography | |
| HK1210181B (en) | Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography |