SI2794635T1 - Ionskoizmenjevalna membranska kromatografija - Google Patents

Ionskoizmenjevalna membranska kromatografija

Info

Publication number
SI2794635T1
SI2794635T1 SI201231443T SI201231443T SI2794635T1 SI 2794635 T1 SI2794635 T1 SI 2794635T1 SI 201231443 T SI201231443 T SI 201231443T SI 201231443 T SI201231443 T SI 201231443T SI 2794635 T1 SI2794635 T1 SI 2794635T1
Authority
SI
Slovenia
Prior art keywords
ion exchange
exchange membrane
membrane chromatography
chromatography
ion
Prior art date
Application number
SI201231443T
Other languages
English (en)
Slovenian (sl)
Inventor
Jerome Joseph Bill Jr.
Arick Michael Brown
Christopher John Dowd
Brooke Ellen Thayer
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47430154&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2794635(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of SI2794635T1 publication Critical patent/SI2794635T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
SI201231443T 2011-12-22 2012-12-18 Ionskoizmenjevalna membranska kromatografija SI2794635T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161579285P 2011-12-22 2011-12-22
PCT/US2012/070373 WO2013096322A1 (en) 2011-12-22 2012-12-18 Ion exchange membrane chromatography
EP12806322.9A EP2794635B8 (en) 2011-12-22 2012-12-18 Ion exchange membrane chromatography

Publications (1)

Publication Number Publication Date
SI2794635T1 true SI2794635T1 (sl) 2018-12-31

Family

ID=47430154

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201231443T SI2794635T1 (sl) 2011-12-22 2012-12-18 Ionskoizmenjevalna membranska kromatografija

Country Status (21)

Country Link
US (3) US10364268B2 (enExample)
EP (2) EP3492486A1 (enExample)
JP (5) JP6605202B2 (enExample)
KR (3) KR102067075B1 (enExample)
CN (2) CN104125963B (enExample)
AR (1) AR089362A1 (enExample)
AU (3) AU2012355356B2 (enExample)
BR (1) BR112014015101A8 (enExample)
CA (1) CA2859376C (enExample)
ES (1) ES2697676T3 (enExample)
HR (1) HRP20181846T1 (enExample)
IL (2) IL267585B (enExample)
MX (2) MX360453B (enExample)
MY (1) MY172426A (enExample)
PL (1) PL2794635T3 (enExample)
RU (1) RU2648999C2 (enExample)
SG (1) SG11201403437TA (enExample)
SI (1) SI2794635T1 (enExample)
TR (1) TR201815709T4 (enExample)
WO (1) WO2013096322A1 (enExample)
ZA (2) ZA201404593B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10364268B2 (en) * 2011-12-22 2019-07-30 Genentech, Inc. Ion exchange membrane chromatography
WO2015088677A1 (en) 2013-12-12 2015-06-18 Emd Millipore Corporation Protein separations using an acrylamide containing filter
KR102344170B1 (ko) * 2013-12-27 2021-12-27 추가이 세이야쿠 가부시키가이샤 등전점이 낮은 항체의 정제방법
CN104693303B (zh) * 2015-02-28 2018-03-13 苏州金盟生物技术有限公司 一种蛋白制品中的核酸去除方法
MA42613A (fr) 2015-08-13 2018-06-20 Amgen Inc Filtration en profondeur chargée de protéines de liaison à un antigène
GB201711481D0 (en) 2017-07-17 2017-08-30 Ucb Biopharma Sprl Protein purification
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
US10792618B2 (en) 2018-06-19 2020-10-06 Sartorius Stedim Biotech Gmbh Particle separation and/or purification of a fluid
KR102140531B1 (ko) * 2018-08-07 2020-08-04 (주)휴온스 Gly-Tβ4의 제조방법
KR102893280B1 (ko) * 2018-08-14 2025-12-01 브리스톨-마이어스 스큅 컴퍼니 개선된 단백질 회수
GB201815405D0 (en) * 2018-09-21 2018-11-07 Fujifilm Mfg Europe Bv Membranes suitable for detecting, filtering and/or purifying biomolecules
WO2020128797A1 (en) * 2018-12-21 2020-06-25 3M Innovative Properties Company Method for testing a chromatography device used for ion exchange
AR119264A1 (es) * 2019-06-05 2021-12-09 Genentech Inc Método para reutilización de cromatografía
JP2023511946A (ja) * 2020-01-24 2023-03-23 アルカームス ファーマ アイルランド リミテッド 精製方法
US11416468B2 (en) * 2020-07-21 2022-08-16 International Business Machines Corporation Active-active system index management
CN116425826A (zh) * 2021-12-30 2023-07-14 广州百济神州生物制药有限公司 一种快速纯化质量样品的方法
CN116371011B (zh) * 2023-05-26 2023-08-18 湖南杰萃生物技术有限公司 一种从桑叶中提取黄酮和生物碱的方法
CN117866038B (zh) * 2024-03-11 2024-05-28 北京百力格生物科技有限公司 纯化含有宿主核酸的带亲和标签的酸性蛋白的方法

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE266710C (enExample)
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DD266710A3 (de) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
JPS6150925A (ja) 1984-08-17 1986-03-13 Toray Ind Inc 抗原または抗体の精製方法
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US5091178A (en) 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
AU626008B2 (en) * 1987-10-23 1992-07-23 Schering Corporation Method of purifying protein
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
WO1989012463A1 (en) 1988-06-21 1989-12-28 Genentech, Inc. Method and therapeutic compositions for the treatment of myocardial infarction
DE68925971T2 (de) 1988-09-23 1996-09-05 Cetus Oncology Corp Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
JP2844346B2 (ja) 1989-05-31 1999-01-06 昭 梶 新規ペプチドならびに新規ｄｎａ
EP0402226A1 (en) 1989-06-06 1990-12-12 Institut National De La Recherche Agronomique Transformation vectors for yeast yarrowia
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
DK0602126T3 (da) 1991-08-14 2003-06-16 Genentech Inc Immunoglobulinvarianter til specifikke FC epsilon-receptorer
DE69233528T2 (de) 1991-11-25 2006-03-16 Enzon, Inc. Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
WO1993016185A2 (en) 1992-02-06 1993-08-19 Creative Biomolecules, Inc. Biosynthetic binding protein for cancer marker
AU687755B2 (en) 1992-08-21 1998-03-05 Genentech Inc. Method for treating an LFA-1-mediated disorder
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US5595721A (en) 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
DK0668877T3 (da) 1993-09-21 1999-09-13 Hemosol Inc Fortrængningschromatografisk fremgangsmåde og oprenset hæmoglobinprodukt
EP0733207B1 (en) 1993-12-10 1997-08-27 Genentech, Inc. Methods for diagnosis of allergy and screening of anti-allergy therapeutics
JP3825798B2 (ja) 1994-01-18 2006-09-27 ジェネンテク，インコーポレイテッド ＩｇＥアンタゴニストを用いる寄生虫感染症の治療法
US5702946A (en) 1994-03-03 1997-12-30 Genentech, Inc. Anti-IL-8 monoclonal antibodies for treatment of inflammatory disorders
US5534615A (en) 1994-04-25 1996-07-09 Genentech, Inc. Cardiac hypertrophy factor and uses therefor
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
US5641870A (en) * 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
JPH11507535A (ja) 1995-06-07 1999-07-06 イムクローン システムズ インコーポレイテッド 腫瘍の成長を抑制する抗体および抗体フラグメント類
ES2183131T3 (es) 1996-01-23 2003-03-16 Genentech Inc Anticuerpos anti-cd18 utilizados contra el ictus cerebral.
CA2242931A1 (en) 1996-01-31 1997-08-07 David Francis Elgar Production of an immunoglobulin enriched fraction from whey protein solutions
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
DK0941344T3 (da) 1996-11-27 2004-09-27 Genentech Inc Humaniserede anti-CD11a-antistoffer
IL132240A0 (en) 1997-04-07 2001-03-19 Genentech Inc Anti-vegf antibodies
EP1860187B1 (en) 1997-05-15 2011-07-13 Genentech, Inc. Apo-2 receptor
US6054293A (en) 1997-07-08 2000-04-25 The Regents Of The University Of California Semaphorin receptors
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
AT500848B1 (de) 1999-06-25 2008-01-15 Genentech Inc Humanisierte anti-erbb2-antikörper
BR0015224A (pt) 1999-10-29 2002-07-09 Genentech Inc Anticorpo anti-antìgeno de célula estaminal prostática (psca) isolado, anticorpo monoclonal anti-psca, ácido nucleico isolado, vetor de expressão, célula, célula hospedeira, método de produção de anticorpo, composição método in vitro para matar uma célula cancerosa que expresse psca, uso de uma anticorpo monoclonal anti-psca e artigo industrializado
EP1301591A4 (en) 2000-07-13 2004-05-26 Invitrogen Corp METHODS AND COMPOSITIONS FOR RAPID EXTRACTION AND ISOLATION OF PROTEINS AND PEPTIDES USING LYING MATRIX
UA83458C2 (uk) 2000-09-18 2008-07-25 Байоджен Айдек Ма Інк. Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
US7321026B2 (en) 2001-06-27 2008-01-22 Skytech Technology Limited Framework-patched immunoglobulins
CA2460819A1 (en) 2001-09-18 2003-03-27 Affinium Pharmaceuticals, Inc. Methods and apparatuses for purification
WO2003033656A2 (en) 2001-10-16 2003-04-24 Exelixis, Inc. MSREBPs AS MODIFIERS OF THE SREBP PATHWAY AND METHODS OF USE
EP1507793A4 (en) 2001-10-17 2006-02-01 Human Genome Sciences Inc NEUTROKIN ALPHA AND NEUTROKIN ALPHA SPLICE VERSION
US20040093621A1 (en) 2001-12-25 2004-05-13 Kyowa Hakko Kogyo Co., Ltd Antibody composition which specifically binds to CD20
RU2004127458A (ru) 2002-02-14 2005-10-27 Иммуномедикс, Инк. (Us) Анти-cd20 антитела, их гибридные белки и способы их использования
KR20110017020A (ko) 2002-10-17 2011-02-18 젠맵 에이/에스 Ｃｄ20에 대한 인간 모노클로날 항체
EP1944320A1 (en) 2002-12-16 2008-07-16 Genentech, Inc. Immunoglobulin variants and uses thereof
CN1206240C (zh) * 2003-04-07 2005-06-15 中国科学院生态环境研究中心 高效离子交换膜色谱纯化卵黄蛋白原技术
KR101351122B1 (ko) 2003-05-09 2014-01-14 듀크 유니버시티 Ｃｄ２０-특이적 항체 및 이를 이용한 방법
AR044388A1 (es) 2003-05-20 2005-09-07 Applied Molecular Evolution Moleculas de union a cd20
US20050079184A1 (en) 2003-08-08 2005-04-14 Immunomedics, Inc. Bispecific antibodies for inducing apoptosis of tumor and diseased cells
US8147832B2 (en) 2003-08-14 2012-04-03 Merck Patent Gmbh CD20-binding polypeptide compositions and methods
US20080274501A1 (en) * 2007-05-02 2008-11-06 Chenming Zhang Method of purifying acidic proteins expressed in plants
US9433922B2 (en) 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
WO2009054226A1 (ja) 2007-10-26 2009-04-30 Asahi Kasei Chemicals Corporation たんぱく質の精製方法
CN105315323A (zh) 2007-10-30 2016-02-10 健泰科生物技术公司 通过阳离子交换层析进行的抗体纯化
WO2009135656A1 (en) * 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
ES2978373T3 (es) * 2008-08-14 2024-09-11 Genentech Inc Métodos para eliminar un contaminante usando cromatografía de membrana de intercambio iónico de desplazamiento de proteínas indígenas
GB0816242D0 (en) 2008-09-05 2008-10-15 Immunobiology Ltd Method of purifying protien complexes
AU2010292897B2 (en) 2009-08-06 2016-01-07 Genentech, Inc. Method to improve virus removal in protein purification
EP3736338A1 (en) * 2009-09-01 2020-11-11 F. Hoffmann-La Roche AG Enhanced protein purification through a modified protein a elution
CA2796633C (en) * 2010-04-23 2020-10-27 Genentech, Inc. Production of heteromultimeric proteins
EP4492053A3 (en) 2010-05-25 2025-03-19 F. Hoffmann-La Roche AG Methods of purifying polypeptides
CN103958017B (zh) * 2011-10-03 2016-01-13 塞克姆公司 用于疏水性置换色谱法的阴离子置换剂分子
US10364268B2 (en) 2011-12-22 2019-07-30 Genentech, Inc. Ion exchange membrane chromatography
WO2015198451A1 (ja) 2014-06-26 2015-12-30 楽天株式会社 情報処理装置、情報処理方法及び情報処理プログラム

Also Published As

Publication number Publication date
US11945837B2 (en) 2024-04-02
AR089362A1 (es) 2014-08-20
IL267585A (en) 2019-08-29
HK1203526A1 (en) 2015-10-30
CN104125963A (zh) 2014-10-29
JP2022101557A (ja) 2022-07-06
US20240247027A1 (en) 2024-07-25
JP2021169454A (ja) 2021-10-28
ZA201903994B (en) 2023-12-20
ZA201404593B (en) 2022-12-21
JP2018109024A (ja) 2018-07-12
MX2014007622A (es) 2014-09-22
AU2020201070A1 (en) 2020-03-05
SG11201403437TA (en) 2014-07-30
BR112014015101A2 (pt) 2017-06-13
BR112014015101A8 (pt) 2021-06-08
JP6605202B2 (ja) 2019-11-13
EP2794635A1 (en) 2014-10-29
WO2013096322A8 (en) 2014-02-27
EP2794635B8 (en) 2018-11-14
JP7402011B2 (ja) 2023-12-20
KR20200008022A (ko) 2020-01-22
NZ626949A (en) 2016-11-25
CA2859376C (en) 2022-04-19
RU2648999C2 (ru) 2018-03-29
TR201815709T4 (tr) 2018-11-21
JP7359807B2 (ja) 2023-10-11
CA2859376A1 (en) 2013-06-27
AU2012355356B2 (en) 2017-10-12
AU2012355356A1 (en) 2014-07-10
ES2697676T3 (es) 2019-01-25
KR20210025692A (ko) 2021-03-09
WO2013096322A9 (en) 2013-08-22
US20200102346A1 (en) 2020-04-02
IL233158A0 (en) 2014-07-31
JP2020040952A (ja) 2020-03-19
MX360453B (es) 2018-11-01
AU2018200194A1 (en) 2018-02-01
WO2013096322A1 (en) 2013-06-27
MY172426A (en) 2019-11-25
CN108892706A (zh) 2018-11-27
EP3492486A1 (en) 2019-06-05
RU2014130017A (ru) 2016-02-10
HRP20181846T1 (hr) 2018-12-28
IL233158B (en) 2019-07-31
MX2018013356A (es) 2020-09-14
PL2794635T3 (pl) 2019-02-28
AU2018200194B2 (en) 2019-11-14
US10364268B2 (en) 2019-07-30
KR20140114834A (ko) 2014-09-29
CN104125963B (zh) 2018-08-17
KR102067075B1 (ko) 2020-01-17
EP2794635B1 (en) 2018-09-12
JP2015503524A (ja) 2015-02-02
IL267585B (en) 2022-09-01
US20140348845A1 (en) 2014-11-27

Similar Documents

Publication Publication Date Title
IL267585A (en) Ion exchange membrane chromatography
PL2734473T3 (pl) Związki typu granatu przewodzące jony litu
GB201107849D0 (en) Cooperative positioning
EP2667919A4 (en) Humidifier
AP2013007300A0 (en) Fused benzoxazepinones as ion modulators
EP2920586A4 (en) IONIC STRENGTH-MEDIATED pH GRADIENT ION EXCHANGE CHROMATOGRAPHY
IL238131B (en) Coated membranes for ion exchange
EP2692782A4 (en) ION EXCHANGE MEMBRANE
IL225720A0 (en) Antibody purification in one ion exchange chromatography unit
EP2707886A4 (en) ELECTROLYTE
GB2532391B (en) Diaphragm
GB201102347D0 (en) Positioning system
EP2709203A4 (en) CELL SYSTEM
GB201118288D0 (en) Ion-conducting membrane
SG10201701383VA (en) Methods for manufacturing ion exchange membranes
GB201109281D0 (en) Membrane
EP2787567A4 (en) FUEL CELL SYSTEM
GB2494304B (en) Spacer
SG11201400765SA (en) Electrochemical processor alignment system
GB2499313B (en) Ion exchange
ZA201102777B (en) Spacer
GB201120948D0 (en) Flooring membrane
GB201102400D0 (en) Sorbent
GB201109603D0 (en) Spacer for multi-glazed units
AU2011901960A0 (en) Humidifier