ATE121418T1 - Verfahren zur proteinreinigung. - Google Patents

Verfahren zur proteinreinigung.

Info

Publication number
ATE121418T1
ATE121418T1 AT88309824T AT88309824T ATE121418T1 AT E121418 T1 ATE121418 T1 AT E121418T1 AT 88309824 T AT88309824 T AT 88309824T AT 88309824 T AT88309824 T AT 88309824T AT E121418 T1 ATE121418 T1 AT E121418T1
Authority
AT
Austria
Prior art keywords
purification process
protein purification
disclosed
technique
impurities
Prior art date
Application number
AT88309824T
Other languages
English (en)
Inventor
David Naveh
John Chu-Tay Tang
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22340970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE121418(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE121418T1 publication Critical patent/ATE121418T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
AT88309824T 1987-10-23 1988-10-19 Verfahren zur proteinreinigung. ATE121418T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11188687A 1987-10-23 1987-10-23

Publications (1)

Publication Number Publication Date
ATE121418T1 true ATE121418T1 (de) 1995-05-15

Family

ID=22340970

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88309824T ATE121418T1 (de) 1987-10-23 1988-10-19 Verfahren zur proteinreinigung.

Country Status (21)

Country Link
EP (2) EP0391934A1 (de)
JP (1) JPH0788395B2 (de)
KR (1) KR930008447B1 (de)
CN (1) CN1031943C (de)
AT (1) ATE121418T1 (de)
AU (1) AU626008B2 (de)
DE (1) DE3853610T3 (de)
DK (1) DK99690D0 (de)
ES (1) ES2070855T5 (de)
FI (1) FI103974B1 (de)
HU (1) HU204537B (de)
IE (1) IE72219B1 (de)
IL (1) IL88118A (de)
MY (1) MY108512A (de)
NO (1) NO303451B1 (de)
NZ (1) NZ226651A (de)
OA (1) OA09787A (de)
PT (1) PT88813B (de)
TN (1) TNSN88111A1 (de)
WO (1) WO1989003840A1 (de)
ZA (1) ZA887862B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68929566D1 (de) * 1988-05-13 2010-01-28 Amgen Inc Verfahren zur Isolierung und Reinigung von G-CSF
US7217689B1 (en) 1989-10-13 2007-05-15 Amgen Inc. Glycosylation analogs of erythropoietin
US5110913A (en) * 1990-05-25 1992-05-05 Miles Inc. Antibody purification method
US5463029A (en) * 1992-11-23 1995-10-31 Immunex Corporation Purification of fusion proteins comprising GM-CSF and IL-3
WO1995007703A1 (en) * 1993-09-15 1995-03-23 Alpha Therapeutic Corp. Alpha1-acid glycoprotein purification process and product
US5808011A (en) * 1996-07-01 1998-09-15 Biopure Corporation Method for chromatographic removal of prions
US7304150B1 (en) 1998-10-23 2007-12-04 Amgen Inc. Methods and compositions for the prevention and treatment of anemia
IL145597A0 (en) 1999-04-08 2002-06-30 Genentech Inc Composition based on oppositely-charged polypeptides
CA2497364C (en) 2002-09-11 2013-03-19 Chugai Seiyaku Kabushiki Kaisha Protein purification method
DE10360841A1 (de) * 2003-12-20 2005-07-14 Henkel Kgaa Helle, stabile, staub- und geruchsarme Enzymgranulate
KR101660575B1 (ko) * 2005-03-11 2016-09-27 와이어쓰 엘엘씨 약한 분배성 크로마토그래피법
SE529259C2 (sv) * 2005-08-31 2007-06-12 Ge Healthcare Bio Sciences Ab Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi
JP5276004B2 (ja) * 2006-11-10 2013-08-28 マリー ゴールバーン シーオー−オペレイティブ シーオー．リミテッド アンギオゲニンの調製方法
CN101556260B (zh) * 2009-05-25 2012-01-11 北京理工大学 固定化pH梯度毛细管等电聚焦测定微生物等电点的方法
CN101556261B (zh) * 2009-05-25 2012-01-11 北京理工大学 微管内等电聚焦和剪断吹出培养测定微生物等电点的方法
WO2013075740A1 (en) * 2011-11-23 2013-05-30 Sanofi Antibody purification method
AU2012355356B2 (en) * 2011-12-22 2017-10-12 Genentech, Inc. Ion exchange membrane chromatography
TWI675041B (zh) 2013-05-06 2019-10-21 法商賽諾菲公司 用於純化抗體之連續多步驟方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4658018A (en) * 1984-03-13 1987-04-14 Immunex Corporation Process for producing homogeneous colony stimulating factor
IL76360A0 (en) * 1984-09-26 1986-01-31 Takeda Chemical Industries Ltd Mutual separation of proteins
ZA872781B (en) * 1986-05-19 1987-10-05 Immunology Ventures B-cell stimulating factor

Also Published As

Publication number Publication date
MY108512A (en) 1996-10-31
NZ226651A (en) 1990-09-26
IE883168L (en) 1989-04-23
ES2070855T3 (es) 1995-06-16
HUT52783A (en) 1990-08-28
DK99690A (da) 1990-04-23
HU886264D0 (en) 1990-07-28
CN1031943C (zh) 1996-06-05
WO1989003840A1 (en) 1989-05-05
EP0313343A1 (de) 1989-04-26
ZA887862B (en) 1989-06-28
PT88813B (pt) 1993-01-29
KR930008447B1 (ko) 1993-09-04
FI103974B (fi) 1999-10-29
AU626008B2 (en) 1992-07-23
NO901769D0 (no) 1990-04-20
TNSN88111A1 (fr) 1990-07-10
DE3853610T3 (de) 2004-05-13
EP0313343B2 (de) 2003-07-23
OA09787A (en) 1994-04-15
DE3853610T2 (de) 1995-08-31
JPH0788395B2 (ja) 1995-09-27
IL88118A (en) 1993-06-10
AU2624788A (en) 1989-05-23
ES2070855T5 (es) 2004-03-01
EP0391934A1 (de) 1990-10-17
FI902017A0 (fi) 1990-04-23
EP0313343B1 (de) 1995-04-19
HU204537B (en) 1992-01-28
IE72219B1 (en) 1997-04-09
CN1032661A (zh) 1989-05-03
NO303451B1 (no) 1998-07-13
FI103974B1 (fi) 1999-10-29
JPH03500649A (ja) 1991-02-14
IL88118A0 (en) 1989-06-30
NO901769L (no) 1990-04-20
KR890701618A (ko) 1989-12-22
DE3853610D1 (de) 1995-05-24
DK99690D0 (da) 1990-04-23

Similar Documents

Publication Publication Date Title
DE3853610D1 (de) Verfahren zur Proteinreinigung.
PT81754A (en) Processes for purifying tumor necrosis factors and for producing recombinant dna molecules coding for tumor necrosis factor-like compounds and tumor necrosis factors
HUT39462A (en) Process for the purification of proteins
FR2603581B1 (fr) Procede pour isoler et purifier des aminoacides par chromatographie
DE3587422D1 (de) Fuer ein hirudinaehnliches protein kodierende dns-sequenz und verfahren zur herstellung eines solchen proteins.
DE69027818D1 (de) Verfahren zur Reinigung von Aminomethylenphosphonsäuren
DE69025961D1 (de) Verfahren zur Reinigung von Interleukin-4
ATE173272T1 (de) Verfahren zur reaktivierung von gereinigten membranproteinen
ATE97449T1 (de) Methode zur reinigung und isolierung von zwei ionischen formen von somatomedin.
DE69001309T2 (de) Verfahren zur herstellung von antihaemophilem faktor (faktor viii), der eine hohe reinheit aufweist.
DE3580007D1 (de) Verfahren zur reinigung von rohem beta-phenylethylalkohol.
DD267619A3 (de) Verfahren zur herstellung von proteinkonzentraten
AT385995B (de) Verfahren zur herstellung von substituierten alpha-aminosaeuren
ATE38660T1 (de) Verfahren zur reinigung von rohem trifluranil.
DE3486319D1 (de) Verfahren zur Herstellung eines Proteins.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee