JP2019514581A - 眼の薬物送達のためのシステムおよび方法 - Google Patents

眼の薬物送達のためのシステムおよび方法 Download PDF

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Publication number
JP2019514581A
JP2019514581A JP2018557826A JP2018557826A JP2019514581A JP 2019514581 A JP2019514581 A JP 2019514581A JP 2018557826 A JP2018557826 A JP 2018557826A JP 2018557826 A JP2018557826 A JP 2018557826A JP 2019514581 A JP2019514581 A JP 2019514581A
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JP
Japan
Prior art keywords
eye
drug
housing
end portion
distal end
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2018557826A
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English (en)
Japanese (ja)
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JP2019514581A5 (enExample
Inventor
ラファエル ブイ． アンディノ，
ラファエル ブイ． アンディノ，
トーマス エドワード ゴッドフリー，
トーマス エドワード ゴッドフリー，
シェリー エッカート ハンコック，
シェリー エッカート ハンコック，
サミルクマール パテル，
サミルクマール パテル，
ケリー ジョー ストラドホフ，
ケリー ジョー ストラドホフ，
ジェシー ヨー，
ジェシー ヨー，
ブラディミール ザルニトシン，
ブラディミール ザルニトシン，
Original Assignee
クリアサイド バイオメディカル，インコーポレイテッド
クリアサイド バイオメディカル，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of JP2019514581A publication Critical patent/JP2019514581A/ja
Publication of JP2019514581A5 publication Critical patent/JP2019514581A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Electrotherapy Devices (AREA)
JP2018557826A 2016-05-02 2017-05-02 眼の薬物送達のためのシステムおよび方法 Pending JP2019514581A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662330501P 2016-05-02 2016-05-02
US62/330,501 2016-05-02
US201662341149P 2016-05-25 2016-05-25
US62/341,149 2016-05-25
US201662359752P 2016-07-08 2016-07-08
US62/359,752 2016-07-08
US201662378401P 2016-08-23 2016-08-23
US62/378,401 2016-08-23
PCT/US2017/030609 WO2017192565A1 (en) 2016-05-02 2017-05-02 Systems and methods for ocular drug delivery

Publications (2)

Publication Number Publication Date
JP2019514581A true JP2019514581A (ja) 2019-06-06
JP2019514581A5 JP2019514581A5 (enExample) 2020-07-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018557826A Pending JP2019514581A (ja) 2016-05-02 2017-05-02 眼の薬物送達のためのシステムおよび方法

Country Status (5)

Country Link
US (1) US11596545B2 (enExample)
EP (1) EP3452165A1 (enExample)
JP (1) JP2019514581A (enExample)
CA (1) CA3062845A1 (enExample)
WO (1) WO2017192565A1 (enExample)

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WO2011044175A2 (en) 2009-10-06 2011-04-14 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
BR112013009205A2 (pt) 2010-10-15 2016-07-26 Iscience Interventional Corp dispositivo para colocação na esclera de um olho, método para acessar o espaço supracoroidal de um olho, para acessar o espaço subretinal de um olho e para colocar um orifício dentro de um trato escleral em um olho.
AU2012230701B2 (en) 2011-03-24 2016-09-29 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents
CA3240136A1 (en) 2012-11-08 2014-05-15 Clearside Biomedical, Inc. Methods and devices for the treatment of ocular diseases in human subjects
SG10201702674PA (en) 2013-05-03 2017-06-29 Clearside Biomedical Inc Apparatus and methods for ocular injection
EP3003454B1 (en) 2013-06-03 2020-01-08 Clearside Biomedical, Inc. Apparatus for drug delivery using multiple reservoirs
JP2019514581A (ja) 2016-05-02 2019-06-06 クリアサイド バイオメディカル，インコーポレイテッド 眼の薬物送達のためのシステムおよび方法
IL264764B2 (en) 2016-08-12 2024-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a drug administration needle
WO2018204515A1 (en) 2017-05-02 2018-11-08 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
US11517473B2 (en) * 2017-08-27 2022-12-06 Solana Hesith, Inc. Multi-modal thermal therapy for blepharitis, meibomian gland dysfunction and dry eye syndrome
US20200316225A1 (en) 2017-11-29 2020-10-08 Copernicus Therapeutics, Inc. Gene Therapy For Ocular Improvement
AU2019234675A1 (en) 2018-03-13 2020-10-01 Vertex Pharmaceuticals Incorporated Implantation devices, system, and methods
WO2020037294A1 (en) * 2018-08-17 2020-02-20 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of diclophenac and other therapeutic agents
WO2020161342A1 (en) 2019-02-08 2020-08-13 Curevac Ag Coding rna administered into the suprachoroidal space in the treatment of ophtalmic diseases
EP4190395A4 (en) * 2020-08-28 2024-02-21 TERUMO Kabushiki Kaisha DRUG DELIVERY TOOL
US20220313491A1 (en) * 2021-04-02 2022-10-06 Twenty Twenty Therapeutics Llc Passive intraocular pressure control and associated systems, devices, and methods
US20220323254A1 (en) * 2021-04-09 2022-10-13 Innovative Drive Corporation Ablation device for the reduction of intraocular pressure and methods of use
KR20240033230A (ko) * 2021-07-22 2024-03-12 청두 오리젠 바이오테크놀로지 씨오., 엘티디. 안구용 주사 어셈블리, 주사 장치 및 사용 방법
US12310883B2 (en) 2021-07-23 2025-05-27 Ocusci, Inc. Continuous thermal therapy
USD1075029S1 (en) 2021-07-23 2025-05-13 Ocusci, Inc. Thermal therapy instrument
USD1037439S1 (en) 2022-01-17 2024-07-30 EyePoint Pharamaceuticals, Inc. Ocular injector
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